Abstract:
BACKGROUND:Contamination from fecal bacteria in recreational waters is a major health concern since bacteria capable of causing human disease can be found in animal feces. The Dog Beach area of Ocean Beach in San Diego, California is a beach prone to closures due to high levels of fecal indicator bacteria (FIB). A potential source of these FIB could be the canine feces left behind by owners who do not clean up after their pets. We tested this hypothesis by screening the DNA isolated from canine feces for the bacteriophage-encoded stx gene normally found in the virulent strains of the fecal bacterium Escherichia coli. RESULTS:Twenty canine fecal samples were collected, processed for total and bacterial fraction DNA, and screened by PCR for the stx gene. The stx gene was detected in the total and bacterial fraction DNA of one fecal sample. Bacterial isolates were then cultivated from the stx-positive fecal sample. Eighty nine of these canine fecal bacterial isolates were screened by PCR for the stx gene. The stx gene was detected in five of these isolates. Sequencing and phylogenetic analyses of 16S rRNA gene PCR products from the canine fecal bacterial isolates indicated that they were Enterococcus and not E. coli. CONCLUSIONS:The bacteriophage-encoded stx gene was found in multiple species of bacteria cultivated from canine fecal samples gathered at the shoreline of the Dog Beach area of Ocean Beach in San Diego, California. The canine fecal bacteria carrying the stx gene were not the typical E. coli host and were instead identified through phylogenetic analyses as Enterococcus. This suggests a large degree of horizontal gene transfer of exotoxin genes in recreational waters.
journal_name
Gut Pathogjournal_title
Gut pathogensauthors
Casas V,Sobrepeña G,Rodriguez-Mueller B,Ahtye J,Maloy SRdoi
10.1186/1757-4749-3-10subject
Has Abstractpub_date
2011-07-07 00:00:00pages
10issue
1issn
1757-4749pii
1757-4749-3-10journal_volume
3pub_type
杂志文章相关文献
Gut Pathogens文献大全abstract::Of 19 environmental Escherichia coli (n = 12) and Klebsiella pneumoniae (n = 7) tested for quinolone resistance-related genes qnrA, qnrB, qnrC, qnrS and qepA, four each of E. coli and K. pneumoniae possessed qnrS, and another E. coli isolate possessed a new variant of qepA. This is the first detection of qepA in envir...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0207-8
更新日期:2017-10-23 00:00:00
abstract:BACKGROUND:Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the binary toxin (CDT), which is generally found in C. difficile 027 (ST1) and/or 078 (ST11) in clinic. However, we isolated a bi...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0191-z
更新日期:2017-08-07 00:00:00
abstract:BACKGROUND:Multidrug resistance and, in particular, carbapenem resistance is spreading worldwide at an alarming rate, comprehending a variety of bacterial species and causing both nosocomial and community acquired outbursts. Early and efficient detection of infected patients or colonized carriers are mandatory steps in...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-13
更新日期:2014-05-19 00:00:00
abstract:BACKGROUND:Klebsiella pneumoniae is the most common pathogen of community-acquired pyogenic liver abscess in East Asia. Diabetes mellitus (DM) is a well-established risk factor for K. pneumoniae liver abscess (KPLA). However, reports regarding the emergence of KPLA in non-diabetic patients are limited. RESULTS:A total...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-016-0128-y
更新日期:2016-10-18 00:00:00
abstract:BACKGROUND:The human and animal intestinal tract harbors a complex community of microbes which enables bacteria to inherit antibiotic resistance genes. The aims of this study were to investigate clonality, antimicrobial resistance, prevalence and gene cassette arrays of class I and II integrons among commensal Escheric...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-016-0123-3
更新日期:2016-08-30 00:00:00
abstract:Background:Shigella has evolved as a result of acquiring extragenetic material through horizontal gene exchange. These aid in the rapid emergence of bacterial inter-strain diversity in virulence factors and serotype variants through O-antigenic switching. Plasmid incompatibility typing of isolates is insightful in unde...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-019-0314-9
更新日期:2019-06-14 00:00:00
abstract:BACKGROUND:The putative H. pylori pathogenicity-associated factor dupA has been associated with IL-8 induction in vitro, and duodenal ulcer (DU) and gastric cancer (GC) development in certain populations, but this association is inconsistent between studies. We aimed to investigate dupA prevalence in clinical isolates ...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-1-5
更新日期:2009-03-11 00:00:00
abstract:BACKGROUND:Ruminants serve as one of the most important reservoirs for pathogenic Escherichia coli. Infection with E. coli, a foodborne enteropathogen, can lead to asymptomatic infections that can cause life-threatening complications in humans. Therefore, from a clinical and human health perspective, it is important to...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0174-0
更新日期:2017-04-28 00:00:00
abstract:BACKGROUND:Acid treatment is commonly used for controlling or killing pathogenic microorganisms on medical devices and environments; however, inadequate acid treatment may cause acid tolerance response (ATR) and offer cross-protection against environmental stresses, including antimicrobials. This study aimed to charact...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00390-5
更新日期:2020-12-01 00:00:00
abstract:Background:The human gut microbiome has an important role in health and disease. There is extensive geographical variation in the composition of the gut microbiome, however, little is known about the gut microbiome composition of people from the Arabian Peninsula. In this study, we describe the gut microbiome of Arab K...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00351-y
更新日期:2020-02-26 00:00:00
abstract:BACKGROUND:Inflammatory bowel disease (comprising ulcerative colitis and Crohn's disease) is a multifactorial disease that is extensively associated with stool microbiome changes (dysbiosis). Appendicitis and appendectomy limits subsequent colitis, clinically, and in animal models. We wanted to examine how the appendic...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-25
更新日期:2014-06-21 00:00:00
abstract:BACKGROUND:Ruminants, in particular bovines, are the primary reservoir of Shiga toxin-producing E. coli (STEC), but whole genome analyses of the current German ESBL-producing O104:H4 outbreak strain of sequence type (ST) 678 showed this strain to be highly similar to enteroaggregative E. coli (EAEC). Strains of the EAE...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-3-17
更新日期:2011-11-03 00:00:00
abstract:BACKGROUND:One mechanism utilized by bacterial pathogens for host adaptation and immune evasion is the generation of phenotypic diversity by the phasevarion that results from the differential expression of a suite of genes regulated by the activity of a phase-variable methyltransferase within a restriction modification...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-014-0035-z
更新日期:2014-09-05 00:00:00
abstract:BACKGROUND:Recent epidemiological analyses have implicated acute Campylobacter enteritis as a factor that may incite or exacerbate inflammatory bowel disease (IBD) in susceptible individuals. We have demonstrated previously that C. jejuni disrupts the intestinal barrier function by rapidly inducing epithelial transloca...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-2-14
更新日期:2010-11-01 00:00:00
abstract:Background:Extended spectrum beta lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli infections are of global interest because of their clinical and economic impact. The ESBL resistance genes disseminate through plasmids, and are found in successful global lineages such as ST131 and ST648. The carri...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-018-0243-z
更新日期:2018-06-15 00:00:00
abstract::The ability to adhere to host surfaces is by far the most vital step in the successful colonization by microbial pathogens. Colonization begins with the attachment of the bacterium to receptors expressed by cells forming the lining of the mucosa. Long hair like extracellular appendages called fimbriae, produced by mos...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-1-22
更新日期:2009-12-10 00:00:00
abstract:BACKGROUND:We investigated the interaction of Mycobacterium avium subspecies paratuberculosis, M. bovis and M. tuberculosis and different glial cells (enteric glial and microglial cells) in order to evaluate the infecting ability of these microorganisms and the effects produced on these cells, such as the evaluation of...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-3-19
更新日期:2011-12-09 00:00:00
abstract:BACKGROUND:Salmonella enterica serovar Typhi (S. Typhi) exhibits unique characteristics as an intracellular human pathogen. It causes both acute and chronic infection with various disease manifestations in the human host only. The principal factors underlying the unique lifestyle of motility and biofilm forming ability...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-2
更新日期:2014-02-05 00:00:00
abstract:BACKGROUND:Bacillus cereus is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of B. cereus FORC_013 isolated from fried eel in South Korea. To extend our understanding of the genomic characteristics of FORC_013, we conducted a comparative ...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-017-0175-z
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Intestinal microorganisms affect host physiology, including ageing. Given the difficulty in controlling for human studies of the gut microbiome, mouse models provide an alternative avenue to study such relationships. In this study, we report on the complete genome of "Faecalibaculum rodentium" ALO17, a bacte...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-016-0087-3
更新日期:2016-02-12 00:00:00
abstract:BACKGROUND:How host cell glycosylation affects EPEC or EHEC O157:H7 invasion is unclear. This study investigated whether and how O-glycans were involved in EPEC or EHEC O157:H7 invasion into HT-29 cells. RESULTS:Lectin histochemical staining confirmed stronger staining with PNA, which labeled Galβ1, 3 GalNAc (core 1 s...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-015-0078-9
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:One of the working mechanisms of probiotic bacteria is their ability to compete with pathogens. To define the probiotic properties of seven Lactic Acid Bacteria (LAB) strains, we tested them for survival in simulated gastro-intestinal conditions, antimicrobial activities, co-aggregative abilities, and interf...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0162-4
更新日期:2017-03-06 00:00:00
abstract:BACKGROUND:Helicobacter pylori infection is associated with risk for chronic gastritis (CG), gastric ulcer (GU), duodenal ulcer (DU), and gastric cancer (GC). The H. pylori Cag type IV secretion system (TFSS) translocates the virulence factor cytotoxin-associated gene A protein into host cells and plays an important ro...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0165-1
更新日期:2017-04-21 00:00:00
abstract:Background:Acute gastroenteritis (AGE) is diagnosed with a presentation of > 1 episode of vomiting and > 3 episodes of diarrhea in a 24-h period. Treatment is supportive, however, in severe cases antibacterial treatment may be indicated. Stool cultures can detect the responsible pathogenic bacteria and can guide antibi...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00369-2
更新日期:2020-06-22 00:00:00
abstract::[This corrects the article DOI: 10.1186/1757-4749-6-28.]. ...
journal_title:Gut pathogens
pub_type: 已发布勘误
doi:10.1186/s13099-016-0120-6
更新日期:2016-08-10 00:00:00
abstract:BACKGROUND:Coeliac disease is an autoimmune disorder resulting from an interaction between diet, genome and immunity. The treatment of CoeD is lifelong adherence to a gluten free diet, which is associated with clinical and histological improvements. However, a substantive number of individuals report only partial sympt...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0173-1
更新日期:2017-05-05 00:00:00
abstract:BACKGROUND:Widely considered probiotic organisms, Bifidobacteria are common inhabitants of the alimentary tract of animals including insects. Bifidobacteria identified from the honey bee are found in larval guts and throughout the alimentary tract, but attain their greatest abundance in the adult hind gut. To further u...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-5-42
更新日期:2013-12-18 00:00:00
abstract:Background:The root extract of Rhodiola rosea has historically been used in Europe and Asia as an adaptogen, and similar to ginseng and Shisandra, shown to display numerous health benefits in humans, such as decreasing fatigue and anxiety while improving mood, memory, and stamina. A similar extract in the Rhodiola fami...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-018-0239-8
更新日期:2018-03-20 00:00:00
abstract:BACKGROUND:The development of efficacious alternatives to antimicrobial growth promoters (AGP) in livestock production is an urgent issue, but is hampered by a lack of knowledge regarding the mode of action of AGP. The belief that AGP modulate the intestinal microbiota has become prominent in the literature; however, t...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-3-14
更新日期:2011-09-25 00:00:00
abstract:Background:Enterobacter hormaechei is an important emerging pathogen and a key member of the highly diverse Enterobacter cloacae complex. E. hormaechei strains can persist and spread in nosocomial environments, and often exhibit resistance to multiple clinically important antibiotics. However, the genomic regions that ...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-019-0288-7
更新日期:2019-02-13 00:00:00