解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Acid treatment is commonly used for controlling or killing pathogenic microorganisms on medical devices and environments; however, inadequate acid treatment may cause acid tolerance response (ATR) and offer cross-protection against environmental stresses, including antimicrobials. This study aimed to charact...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00390-5
更新日期:2020-12-01 00:00:00
abstract:Introduction:Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP. Yet, the impact of long-term antibiotic prophylaxis on the microbiome of these patients is poorly characterized. Methods:Patients with liver cirrhosis receiv...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00389-y
更新日期:2020-10-30 00:00:00
abstract:Background:Acute gastroenteritis (AGE) is diagnosed with a presentation of > 1 episode of vomiting and > 3 episodes of diarrhea in a 24-h period. Treatment is supportive, however, in severe cases antibacterial treatment may be indicated. Stool cultures can detect the responsible pathogenic bacteria and can guide antibi...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00369-2
更新日期:2020-06-22 00:00:00
abstract::The World Health Organisation, in its 2019 progress report on HIV, viral hepatitis and STDs indicates that 257 million people are afflicted with chronic HBV infections, of which, 1 million patients lose their lives every year due to HBV related chronic liver diseases including serious complications such as liver cirrh...
journal_title:Gut pathogens
pub_type: 杂志文章,评审
doi:10.1186/s13099-020-00353-w
更新日期:2020-04-24 00:00:00
abstract:Background:The human gut microbiome has an important role in health and disease. There is extensive geographical variation in the composition of the gut microbiome, however, little is known about the gut microbiome composition of people from the Arabian Peninsula. In this study, we describe the gut microbiome of Arab K...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-020-00351-y
更新日期:2020-02-26 00:00:00
abstract::As the associations between the gut microbiota and numerous health outcomes become more evident, it is important to conduct longitudinal microbiome research to advance the field beyond the identification of associations. It is also necessary to include individuals who have historically been underrepresented in biomedi...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-019-0324-7
更新日期:2019-08-26 00:00:00
abstract:Background:Shigella has evolved as a result of acquiring extragenetic material through horizontal gene exchange. These aid in the rapid emergence of bacterial inter-strain diversity in virulence factors and serotype variants through O-antigenic switching. Plasmid incompatibility typing of isolates is insightful in unde...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-019-0314-9
更新日期:2019-06-14 00:00:00
abstract:Background:Enterobacter hormaechei is an important emerging pathogen and a key member of the highly diverse Enterobacter cloacae complex. E. hormaechei strains can persist and spread in nosocomial environments, and often exhibit resistance to multiple clinically important antibiotics. However, the genomic regions that ...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-019-0288-7
更新日期:2019-02-13 00:00:00
abstract:Background:Extended spectrum beta lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli infections are of global interest because of their clinical and economic impact. The ESBL resistance genes disseminate through plasmids, and are found in successful global lineages such as ST131 and ST648. The carri...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-018-0243-z
更新日期:2018-06-15 00:00:00
abstract:Background:Campylobacter jejuni is considered as a chicken commensal. The gut microbiota and the immune status of the host may affect its colonization. Infectious bursal disease virus (IBDV) is an immunosuppressive virus of chickens, which allows secondary pathogens to invade or exacerbates their pathogenesis. To inves...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-018-0241-1
更新日期:2018-03-30 00:00:00
abstract:Background:The root extract of Rhodiola rosea has historically been used in Europe and Asia as an adaptogen, and similar to ginseng and Shisandra, shown to display numerous health benefits in humans, such as decreasing fatigue and anxiety while improving mood, memory, and stamina. A similar extract in the Rhodiola fami...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-018-0239-8
更新日期:2018-03-20 00:00:00
abstract:Background:After an environmental disaster, the affected community is at increased risk for persistent abdominal pain but mechanisms are unclear. Therefore, our study aimed to determine association between abdominal pain and poor water, sanitation and hygiene (WaSH) practices, and if small intestinal bacterial overgrow...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0224-7
更新日期:2017-12-14 00:00:00
abstract:Background:Recent advances in next-generation sequencing technologies have enabled comprehensive analysis of the gut microbiota, which is closely linked to the health of the host. Consequently, several studies have explored the factors affecting gut microbiota composition. In recent years, increasing number of dog owne...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0218-5
更新日期:2017-11-21 00:00:00
abstract::Of 19 environmental Escherichia coli (n = 12) and Klebsiella pneumoniae (n = 7) tested for quinolone resistance-related genes qnrA, qnrB, qnrC, qnrS and qepA, four each of E. coli and K. pneumoniae possessed qnrS, and another E. coli isolate possessed a new variant of qepA. This is the first detection of qepA in envir...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0207-8
更新日期:2017-10-23 00:00:00
abstract:BACKGROUND:Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the binary toxin (CDT), which is generally found in C. difficile 027 (ST1) and/or 078 (ST11) in clinic. However, we isolated a bi...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0191-z
更新日期:2017-08-07 00:00:00
abstract:BACKGROUND:Shiga toxin (Stx) producing Escherichia coli (E. coli) (STEC) is the most frequent cause of diarrhoea-positive haemolytic uraemic syndrome (D + HUS) in humans. In 2011, a huge outbreak with an STEC O104:H4 strain in Germany highlighted the limited possibilities for causative treatment of this syndrome. The r...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0179-8
更新日期:2017-05-25 00:00:00
abstract:BACKGROUND:Bacillus cereus is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of B. cereus FORC_013 isolated from fried eel in South Korea. To extend our understanding of the genomic characteristics of FORC_013, we conducted a comparative ...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-017-0175-z
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Coeliac disease is an autoimmune disorder resulting from an interaction between diet, genome and immunity. The treatment of CoeD is lifelong adherence to a gluten free diet, which is associated with clinical and histological improvements. However, a substantive number of individuals report only partial sympt...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0173-1
更新日期:2017-05-05 00:00:00
abstract:BACKGROUND:In 2007, a nationwide Salmonella Tennessee outbreak occurred via contaminated peanut butter. Here, we developed a single-nucleotide polymorphism (SNP)-typing method for S. Tennessee to determine the clonal subtypes of S. Tennessee that were associated with the peanut butter outbreak. METHODS AND RESULTS:One...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0176-y
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Ruminants serve as one of the most important reservoirs for pathogenic Escherichia coli. Infection with E. coli, a foodborne enteropathogen, can lead to asymptomatic infections that can cause life-threatening complications in humans. Therefore, from a clinical and human health perspective, it is important to...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0174-0
更新日期:2017-04-28 00:00:00
abstract:BACKGROUND:Helicobacter pylori infection is associated with risk for chronic gastritis (CG), gastric ulcer (GU), duodenal ulcer (DU), and gastric cancer (GC). The H. pylori Cag type IV secretion system (TFSS) translocates the virulence factor cytotoxin-associated gene A protein into host cells and plays an important ro...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0165-1
更新日期:2017-04-21 00:00:00
abstract:BACKGROUND:There are multiple etiologies responsible for infectious gastroenteritis causing acute diarrhea which are often under diagnosed. Also acute diarrhea is one of the major causes of morbidity and mortality among children less than 5 years of age. METHODS:In our study, fecal samples (n = 130) were collected fro...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0166-0
更新日期:2017-04-11 00:00:00
abstract:BACKGROUND:One of the working mechanisms of probiotic bacteria is their ability to compete with pathogens. To define the probiotic properties of seven Lactic Acid Bacteria (LAB) strains, we tested them for survival in simulated gastro-intestinal conditions, antimicrobial activities, co-aggregative abilities, and interf...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0162-4
更新日期:2017-03-06 00:00:00
abstract:BACKGROUND:Toll-like receptors (TLRs) are the major pattern recognition receptors that mediate sensing of a wide range of microorganisms. TLR2 forms heterodimers with either TLR1 or TLR6, broadening its ligand diversity against pathogens. TLR1, TLR2 and TLR6 have been implicated in the recognition of Candida albicans, ...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-017-0158-0
更新日期:2017-02-15 00:00:00
abstract:BACKGROUND:Cronobacter sakazakii is an emerging opportunistic pathogen that is associated with rare but life-threatening cases of severe diseases: meningitis, necrotizing enterocolitis, and sepsis in premature and full-term infants. However, the pathogenesis mechanism of this pathogen remains largely unknown. To determ...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-016-0150-0
更新日期:2017-01-04 00:00:00
abstract::We evaluated the effects of the probiotic Escherichia coli Nissle 1917 (EcN) and the antibiotic Ciprofloxacin (Cipro) on mRNA expression of intestinal epithelial cells (IEC) in gnotobiotic (Gn) piglets colonized with a defined commensal microflora (DMF) and inoculated with human rotavirus (HRV) that infects IECs. We a...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-016-0148-7
更新日期:2016-12-13 00:00:00
abstract:BACKGROUND:Human parechovirus (HPeV) is a genus of virus in the family Picornaviridae, having two species A and B. HPeVs are common infectious agents, usually causing mild diarrhea and respiratory disease in young children. RESULTS:Here, we collected and sequenced the near complete genome sequences of 17 novel HPeVs f...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-016-0135-z
更新日期:2016-11-08 00:00:00
abstract:BACKGROUND:Klebsiella pneumoniae is the most common pathogen of community-acquired pyogenic liver abscess in East Asia. Diabetes mellitus (DM) is a well-established risk factor for K. pneumoniae liver abscess (KPLA). However, reports regarding the emergence of KPLA in non-diabetic patients are limited. RESULTS:A total...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-016-0128-y
更新日期:2016-10-18 00:00:00
abstract:BACKGROUND:The human and animal intestinal tract harbors a complex community of microbes which enables bacteria to inherit antibiotic resistance genes. The aims of this study were to investigate clonality, antimicrobial resistance, prevalence and gene cassette arrays of class I and II integrons among commensal Escheric...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-016-0123-3
更新日期:2016-08-30 00:00:00
abstract::[This corrects the article DOI: 10.1186/1757-4749-6-28.]. ...
journal_title:Gut pathogens
pub_type: 已发布勘误
doi:10.1186/s13099-016-0120-6
更新日期:2016-08-10 00:00:00
abstract:BACKGROUND:Typhoid fever has caused severe epidemics in many Asian and African countries. The early detection of outbreaks and their sources may promote the prevention and control of typhoid fever, for which effective and timely molecular subtyping techniques are required. Pulsed field gel electrophoresis (PFGE) is rou...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-016-0094-4
更新日期:2016-04-04 00:00:00
abstract:BACKGROUND:Intestinal microorganisms affect host physiology, including ageing. Given the difficulty in controlling for human studies of the gut microbiome, mouse models provide an alternative avenue to study such relationships. In this study, we report on the complete genome of "Faecalibaculum rodentium" ALO17, a bacte...
journal_title:Gut pathogens
pub_type:
doi:10.1186/s13099-016-0087-3
更新日期:2016-02-12 00:00:00
abstract:BACKGROUND:How host cell glycosylation affects EPEC or EHEC O157:H7 invasion is unclear. This study investigated whether and how O-glycans were involved in EPEC or EHEC O157:H7 invasion into HT-29 cells. RESULTS:Lectin histochemical staining confirmed stronger staining with PNA, which labeled Galβ1, 3 GalNAc (core 1 s...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-015-0078-9
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:Enterotoxigenic Escherichia coli (ETEC) is an important pathogen that causes childhood and travelers' diarrhea. Here, we present the draft genomes of four ETEC isolates recovered from stool specimens of patients with diarrhea in Beijing, China and Dhaka, Bangladesh, respectively. RESULTS:We obtained the dra...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-015-0059-z
更新日期:2015-04-08 00:00:00
abstract:HYPOTHESIS:A healthy gut with normal intestinal microflora is completely disrupted by oral antibiotics. The byproducts of harmful gut bacteria can interfere with brain development and may contribute to autism. Strategies to improve the gut microflora profile through dietary modification may help to alleviate gut disord...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-015-0054-4
更新日期:2015-03-22 00:00:00
abstract:BACKGROUND:Probiotics and prebiotics are promising strategies to counteract Salmonella prevalence in swine. In the present study, we investigated the effects of prebiotics (fructo- (FOS), galacto- (GOS) and mannan- (MOS) oligosaccharides) and the bacteriocinogenic Bifidobacterium thermophilum RBL67 (RBL67) on Salmonell...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-014-0044-y
更新日期:2014-10-24 00:00:00
abstract:BACKGROUND:One mechanism utilized by bacterial pathogens for host adaptation and immune evasion is the generation of phenotypic diversity by the phasevarion that results from the differential expression of a suite of genes regulated by the activity of a phase-variable methyltransferase within a restriction modification...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/s13099-014-0035-z
更新日期:2014-09-05 00:00:00
abstract:BACKGROUND:Shigellosis is an acute form of gastroenteritis caused by the bacteria belonging to the genus Shigella. It is the most common cause of morbidity and mortality in children. Shigella belongs to the family Enterobactericeae, which is a Gram-negative and rod shaped bacterium. In the present study, we report the ...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-28
更新日期:2014-07-11 00:00:00
abstract:BACKGROUND:Inflammatory bowel disease (comprising ulcerative colitis and Crohn's disease) is a multifactorial disease that is extensively associated with stool microbiome changes (dysbiosis). Appendicitis and appendectomy limits subsequent colitis, clinically, and in animal models. We wanted to examine how the appendic...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-25
更新日期:2014-06-21 00:00:00
abstract:BACKGROUND:Multidrug resistance and, in particular, carbapenem resistance is spreading worldwide at an alarming rate, comprehending a variety of bacterial species and causing both nosocomial and community acquired outbursts. Early and efficient detection of infected patients or colonized carriers are mandatory steps in...
journal_title:Gut pathogens
pub_type: 杂志文章
doi:10.1186/1757-4749-6-13
更新日期:2014-05-19 00:00:00