Abstract：
BACKGROUND:Bacillus cereus is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of B. cereus FORC_013 isolated from fried eel in South Korea. To extend our understanding of the genomic characteristics of FORC_013, we conducted a comparative analysis with the published genomes of other B. cereus strains. RESULTS:We fully assembled the single circular chromosome (5,418,913 bp) and one plasmid (259,749 bp); 5511 open reading frames (ORFs) and 283 ORFs were predicted for the chromosome and plasmid, respectively. Moreover, we detected that the enterotoxin (NHE, HBL, CytK) induces food-borne illness with diarrheal symptom, and that the pleiotropic regulator, along with other virulence factors, plays a role in surviving and biofilm formation. Through comparative analysis using the complete genome sequence of B. cereus FORC_013, we identified both positively selected genes related to virulence regulation and 224 strain-specific genes of FORC_013. CONCLUSIONS:Through genome analysis of B. cereus FORC_013, we identified multiple virulence factors that may contribute to pathogenicity. These results will provide insight into further studies regarding B. cereus pathogenesis mechanism at the genomic level.
journal_name
Gut Pathogjournal_title
Gut pathogensauthors
Koo HJ,Ahn S,Chung HY,Kim S,Kim K,Ryu S,Lee JH,Choi SH,Kim Hdoi
10.1186/s13099-017-0175-zsubject
Has Abstractpub_date
2017-05-15 00:00:00pages
29issn
1757-4749pii
175journal_volume
9pub_type
相关文献
Gut Pathogens文献大全abstract：Background:Campylobacter jejuni is considered as a chicken commensal. The gut microbiota and the immune status of the host may affect its colonization. Infectious bursal disease virus (IBDV) is an immunosuppressive virus of chickens, which allows secondary pathogens to invade or exacerbates their pathogenesis. To inves...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-018-0241-1
更新日期：2018-03-30 00:00:00
abstract：BACKGROUND:The development of efficacious alternatives to antimicrobial growth promoters (AGP) in livestock production is an urgent issue, but is hampered by a lack of knowledge regarding the mode of action of AGP. The belief that AGP modulate the intestinal microbiota has become prominent in the literature; however, t...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-3-14
更新日期：2011-09-25 00:00:00
abstract：BACKGROUND:We investigated the interaction of Mycobacterium avium subspecies paratuberculosis, M. bovis and M. tuberculosis and different glial cells (enteric glial and microglial cells) in order to evaluate the infecting ability of these microorganisms and the effects produced on these cells, such as the evaluation of...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-3-19
更新日期：2011-12-09 00:00:00
abstract：BACKGROUND:Thermotolerant Campylobacter jejuni, coli and lari are recognized as leading food-borne pathogens causing an acute bacterial enteritis worldwide. Due to narrow spectrum of their biochemical activity, it is very complicated to distinguish between individual species. For reliable risk assessment, proper incide...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-6-12
更新日期：2014-05-09 00:00:00
abstract：Background:Acute gastroenteritis (AGE) is diagnosed with a presentation of > 1 episode of vomiting and > 3 episodes of diarrhea in a 24-h period. Treatment is supportive, however, in severe cases antibacterial treatment may be indicated. Stool cultures can detect the responsible pathogenic bacteria and can guide antibi...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-020-00369-2
更新日期：2020-06-22 00:00:00
abstract：Background:The human gut microbiome has an important role in health and disease. There is extensive geographical variation in the composition of the gut microbiome, however, little is known about the gut microbiome composition of people from the Arabian Peninsula. In this study, we describe the gut microbiome of Arab K...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-020-00351-y
更新日期：2020-02-26 00:00:00
abstract：BACKGROUND:Acid treatment is commonly used for controlling or killing pathogenic microorganisms on medical devices and environments; however, inadequate acid treatment may cause acid tolerance response (ATR) and offer cross-protection against environmental stresses, including antimicrobials. This study aimed to charact...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-020-00390-5
更新日期：2020-12-01 00:00:00
abstract：Background:After an environmental disaster, the affected community is at increased risk for persistent abdominal pain but mechanisms are unclear. Therefore, our study aimed to determine association between abdominal pain and poor water, sanitation and hygiene (WaSH) practices, and if small intestinal bacterial overgrow...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-017-0224-7
更新日期：2017-12-14 00:00:00
abstract：BACKGROUND:In 2005, the first disease-specific Helicobacter pylori virulence factor that induced duodenal ulcer and had a suppressive action on gastric cancer has been identified, and was named duodenal ulcer promoting gene (dupA). However, the importance of the dupA gene on clinical outcomes is conflicting in subseque...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-2-13
更新日期：2010-10-31 00:00:00
abstract：BACKGROUND:Probiotics and prebiotics are promising strategies to counteract Salmonella prevalence in swine. In the present study, we investigated the effects of prebiotics (fructo- (FOS), galacto- (GOS) and mannan- (MOS) oligosaccharides) and the bacteriocinogenic Bifidobacterium thermophilum RBL67 (RBL67) on Salmonell...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-014-0044-y
更新日期：2014-10-24 00:00:00
abstract：BACKGROUND:Salmonella enterica serovar Typhi (S. Typhi) exhibits unique characteristics as an intracellular human pathogen. It causes both acute and chronic infection with various disease manifestations in the human host only. The principal factors underlying the unique lifestyle of motility and biofilm forming ability...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-6-2
更新日期：2014-02-05 00:00:00
abstract：UNLABELLED: BACKGROUND:Following Helicobacter pylori eradication in idiopathic parkinsonism (IP), hypokinesia improved but flexor-rigidity increased. Small intestinal bacterial-overgrowth (SIBO) is a candidate driver of the rigidity: hydrogen-breath-test-positivity is common in IP and case histories suggest that Helic...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-4-12
更新日期：2012-10-19 00:00:00
abstract：BACKGROUND:Campylobacter enteritis represents a risk factor for the development of inflammatory bowel disease (IBD) via unknown mechanisms. As IBD patients exhibit inflammatory responses to their commensal intestinal microflora, factors that induce translocation of commensal bacteria across the intestinal epithelium ma...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-1-2
更新日期：2009-02-03 00:00:00
abstract：BACKGROUND:Intestinal microorganisms affect host physiology, including ageing. Given the difficulty in controlling for human studies of the gut microbiome, mouse models provide an alternative avenue to study such relationships. In this study, we report on the complete genome of "Faecalibaculum rodentium" ALO17, a bacte...
journal_title：Gut pathogens
pub_type：
doi：10.1186/s13099-016-0087-3
更新日期：2016-02-12 00:00:00
abstract：BACKGROUND:Klebsiella pneumoniae is the most common pathogen of community-acquired pyogenic liver abscess in East Asia. Diabetes mellitus (DM) is a well-established risk factor for K. pneumoniae liver abscess (KPLA). However, reports regarding the emergence of KPLA in non-diabetic patients are limited. RESULTS:A total...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-016-0128-y
更新日期：2016-10-18 00:00:00
abstract：BACKGROUND:In 2007, a nationwide Salmonella Tennessee outbreak occurred via contaminated peanut butter. Here, we developed a single-nucleotide polymorphism (SNP)-typing method for S. Tennessee to determine the clonal subtypes of S. Tennessee that were associated with the peanut butter outbreak. METHODS AND RESULTS:One...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-017-0176-y
更新日期：2017-05-01 00:00:00
abstract：Background:Extended spectrum beta lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli infections are of global interest because of their clinical and economic impact. The ESBL resistance genes disseminate through plasmids, and are found in successful global lineages such as ST131 and ST648. The carri...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-018-0243-z
更新日期：2018-06-15 00:00:00
abstract：BACKGROUND:Widely considered probiotic organisms, Bifidobacteria are common inhabitants of the alimentary tract of animals including insects. Bifidobacteria identified from the honey bee are found in larval guts and throughout the alimentary tract, but attain their greatest abundance in the adult hind gut. To further u...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-5-42
更新日期：2013-12-18 00:00:00
abstract：BACKGROUND:Recently, we found that the probiotic strain Bacillus coagulans GBI-30, 6086 (GanedenBC30) improved indices of Clostridium difficile (C. difficile)-induced colitis in mice (Fitzpatrick et al., Gut Pathogens, 2011). Our goal was to determine if BC30 could also prevent the recurrence of C. difficile-induced co...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-4-13
更新日期：2012-10-22 00:00:00
abstract：BACKGROUND:Ruminants, in particular bovines, are the primary reservoir of Shiga toxin-producing E. coli (STEC), but whole genome analyses of the current German ESBL-producing O104:H4 outbreak strain of sequence type (ST) 678 showed this strain to be highly similar to enteroaggregative E. coli (EAEC). Strains of the EAE...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-3-17
更新日期：2011-11-03 00:00:00
abstract：:[This corrects the article DOI: 10.1186/1757-4749-6-28.]. ...
journal_title：Gut pathogens
pub_type： 已发布勘误
doi：10.1186/s13099-016-0120-6
更新日期：2016-08-10 00:00:00
abstract：:Rapid scientific and technological advances have allowed for a more detailed understanding of the relevance of intestinal microbiota, and the entire body-wide microbiome, to human health and well-being. Rodent studies have provided suggestive evidence that probiotics (e.g. lactobacillus and bifidobacteria) can influen...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-5-4
更新日期：2013-03-16 00:00:00
abstract：BACKGROUND:There are multiple etiologies responsible for infectious gastroenteritis causing acute diarrhea which are often under diagnosed. Also acute diarrhea is one of the major causes of morbidity and mortality among children less than 5 years of age. METHODS:In our study, fecal samples (n = 130) were collected fro...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-017-0166-0
更新日期：2017-04-11 00:00:00
abstract：BACKGROUND:Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the binary toxin (CDT), which is generally found in C. difficile 027 (ST1) and/or 078 (ST11) in clinic. However, we isolated a bi...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-017-0191-z
更新日期：2017-08-07 00:00:00
abstract：BACKGROUND:One mechanism utilized by bacterial pathogens for host adaptation and immune evasion is the generation of phenotypic diversity by the phasevarion that results from the differential expression of a suite of genes regulated by the activity of a phase-variable methyltransferase within a restriction modification...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-014-0035-z
更新日期：2014-09-05 00:00:00
abstract：BACKGROUND:The putative H. pylori pathogenicity-associated factor dupA has been associated with IL-8 induction in vitro, and duodenal ulcer (DU) and gastric cancer (GC) development in certain populations, but this association is inconsistent between studies. We aimed to investigate dupA prevalence in clinical isolates ...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-1-5
更新日期：2009-03-11 00:00:00
abstract：HYPOTHESIS:A healthy gut with normal intestinal microflora is completely disrupted by oral antibiotics. The byproducts of harmful gut bacteria can interfere with brain development and may contribute to autism. Strategies to improve the gut microflora profile through dietary modification may help to alleviate gut disord...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-015-0054-4
更新日期：2015-03-22 00:00:00
abstract：BACKGROUND:Contamination from fecal bacteria in recreational waters is a major health concern since bacteria capable of causing human disease can be found in animal feces. The Dog Beach area of Ocean Beach in San Diego, California is a beach prone to closures due to high levels of fecal indicator bacteria (FIB). A pote...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/1757-4749-3-10
更新日期：2011-07-07 00:00:00
abstract：:The World Health Organisation, in its 2019 progress report on HIV, viral hepatitis and STDs indicates that 257 million people are afflicted with chronic HBV infections, of which, 1 million patients lose their lives every year due to HBV related chronic liver diseases including serious complications such as liver cirrh...
journal_title：Gut pathogens
pub_type： 杂志文章,评审
doi：10.1186/s13099-020-00353-w
更新日期：2020-04-24 00:00:00
abstract：BACKGROUND:Ruminants serve as one of the most important reservoirs for pathogenic Escherichia coli. Infection with E. coli, a foodborne enteropathogen, can lead to asymptomatic infections that can cause life-threatening complications in humans. Therefore, from a clinical and human health perspective, it is important to...
journal_title：Gut pathogens
pub_type： 杂志文章
doi：10.1186/s13099-017-0174-0
更新日期：2017-04-28 00:00:00
