当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Regulation of the equilibrium between G-quadruplex and duplex DNA in promoter of human c-myc oncogene by a pyrene derivative.

Regulation of the equilibrium between G-quadruplex and duplex DNA in promoter of human c-myc oncogene by a pyrene derivative.

Abstract：

:It has been established that the equilibrium between duplex and G-quadruplex of the nuclease hypersensitivity element III1 (NHE III1) in human c-myc promoter is linked with this gene's transcription. Using NMR and ESI-MS, we have found a pyrene derivative, DMAPP, is able to modulate this equilibrium and, thus, might have the potential to regulate this oncogene's transcription. DMAPP has shown as a G-quadruplex binding agent and could induce c-myc G-quadruplex formation out of duplex. These results provide new clue for rational drug design to target transcription control of c-myc.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Zhang Z,He X,Yuan G

doi

10.1016/j.ijbiomac.2011.05.024

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1173-6

issue

5

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(11)00219-4

journal_volume

49

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Effect of high energy ball milling on organic pollutant adsorption properties of chitosan.

    abstract：:In the present work, chitosan physicochemical transformations that occur during high energy ball milling are investigated and correlated with adsorption capacity of organic pollutants (using azo-dye reactive red 2 as molecular probe). Experimental results reveal that chitosan ball milled for 1 h shows a 70% increase o...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.01.171

    authors： Qiu W,Vakili M,Cagnetta G,Huang J,Yu G

    更新日期：2020-04-01 00:00:00

  • Decolorization affects the structural characteristics and antioxidant activity of polysaccharides from Thesium chinense Turcz: Comparison of activated carbon and hydrogen peroxide decolorization.

    abstract：:Different decolorization methods have different effects on the properties of polysaccharides. In this study, polysaccharides extracted from Thesium chinense Turcz (T. chinense) were decolorized using either hydrogen peroxide (H2O2), which has been previously reported, or activated carbon. To begin, the conditions for ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.11.074

    authors： Shao L,Sun Y,Liang J,Li M,Li X

    更新日期：2020-07-15 00:00:00

  • Sulfated modification of the polysaccharides from Crassostrea gigas and their antioxidant and hepatoprotective activities through metabolomics analysis.

    abstract：:Sulfated polysaccharides from Crassostrea gigas (SCGP) were successfully prepared using chlorosulfonic acid-pyridine method. The structure of SCGP was determined by high performance liquid chromatography (HPLC), Fourier transform infrared spectrometry (FT-IR) and nuclear magnetic resonance (NMR). The results of spectr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.02.053

    authors： Zhao G,Zhai X,Qu M,Tong C,Li W

    更新日期：2019-05-15 00:00:00

  • Preparation of Ag-cellulose nanocomposite for the selective detection and quantification of mercury at nanomolar level and the evaluation of its photocatalytic performance.

    abstract：:Mercury is a toxic heavy metal that reaches to the water bodies mainly by coal burning, mining and petrol refining. The study was focused to investigate the application of Ag-cellulose nanocomposite to detect and quantify mercury colorimetrically. The Ag-cellulose nanocomposite was characterized by X-ray diffraction, ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.07.119

    authors： Balasurya S,Syed A,Thomas AM,Bahkali AH,Al-Rashed S,Elgorban AM,Raju LL,Das A,Khan SS

    更新日期：2020-12-01 00:00:00

  • Isolation and processing of silk proteins for biomedical applications.

    abstract：:Silk proteins of silkworms are chiefly composed of core fibroin protein and glycoprotein sericin that glues fibroin. Unique mechanical properties, cyto-compatibility and controllable biodegradability facilitate the use of fibroin in biomedical applications. Sericin serves as additive in cosmetic and food industries, a...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.06.022

    authors： Kundu B,Kurland NE,Yadavalli VK,Kundu SC

    更新日期：2014-09-01 00:00:00

  • Use of cellulose nanofibril (CNF)/silver nanoparticles (AgNPs) composite in salt hydrate phase change material for efficient thermal energy storage.

    abstract：:Salt hydrate phase change materials (PCMs) possess the challenge of supercooling, which must be addressed to allow more efficient energy storage and utilisation. In this work, cellulose nanofibril (CNF), a versatile biopolymer was used to support and disperse silver nanoparticles (AgNPs), and the synthesised CNF/AgNPs...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2021.01.183

    authors： Shen Z,Oh K,Kwon S,Toivakka M,Lee HL

    更新日期：2021-01-30 00:00:00

  • Cu2+, Ca2+, and methionine oxidation expose the hydrophobic α-synuclein NAC domain.

    abstract：:α-Synuclein is an intrinsically disordered protein whose aggregation is related to Parkinson's disease and other neurodegenerative disorders. Metal cations are one of the main factors affecting the propensity of α-synuclein to aggregate, either by directly binding to it or by catalyzing the production of reactive oxyg...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.12.018

    authors： Ramis R,Ortega-Castro J,Vilanova B,Adrover M,Frau J

    更新日期：2021-02-01 00:00:00

  • Selective regulation of RANKL/RANK/OPG pathway by heparan sulfate through the binding with estrogen receptor β in MC3T3-E1 cells.

    abstract：:Heparan sulfate (HS) is a linear anionic polysaccharide with repeating sulfated disaccharide units, which has been proven with various regulatory osteogenesis effects through multi-pathway signaling, but its impacts on receptor-activator of nuclear factor kappa beta ligand/receptor-activator of nuclear factor kappa be...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.07.308

    authors： Liu Y,Xu Z,Wang Q,Jiang Y,Wang R,Chen S,Zhu J,Zhang Y,Chen J

    更新日期：2020-10-15 00:00:00

  • In situ preparation of glycoconjugate hollow microspheres mimics the extracellular matrix via interfacial polymerization.

    abstract：:A novel chitin-graft-polyleucine microsphere with hollow construction was prepared via ring-opening polymerization initiated with chitin based on interfacial protocol. The FT-IR and (1)H NMR analysis demonstrated the conjugation with regulated graft length. The study provided a facile one-step route to obtain microsph...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2008.02.007

    authors： Wang J,Liu C,Chi P

    更新日期：2008-06-01 00:00:00

  • A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannai Ino: purification, structure identification and anticoagulant activity.

    abstract：:A novel glycosaminoglycan-like sulfated polysaccharide (AAP) from the pleopods of Haliotis discus hannai Ino was purified by DEAE ion exchange chromatography followed with S-300 HR geltrion chromatography. Chemical composition analysis indicated that AAP was composed of galactosamine, glucuronic acid, fucose, galactos...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2011.09.017

    authors： Li G,Chen S,Wang Y,Xue Y,Chang Y,Li Z,Wang J,Xue C

    更新日期：2011-12-01 00:00:00

  • Pasting and paste properties of waxy rice starch as affected by hydroxypropyl methylcellulose and its viscosity.

    abstract：:The objective of this study was to investigate the impacts of hydroxypropyl methylcellulose (HPMC) and its viscosity on the pasting and paste properties of waxy rice starch (WRS). HPMC with different viscosities (low, BN50; medium, BN40M; high, BN40H) but similar substituted group contents was used. Although the total...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.10.250

    authors： Lee H,Kim HS

    更新日期：2020-06-15 00:00:00

  • Distribution of solvent and ligand molecules around aromatic side chains in proteins and its implication on carbonic anhydrase catalytic mechanism.

    abstract：:Interactions between aromatic phenylalanine, tyrosine and tryptophan residues and water as well as ligand molecules were analyzed by a computer search of a large number of high resolution structures in the protein data bank. Water molecules and oxygen ligands have a preference for the edges of the aromatic residues, b...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(95)01068-8

    authors： Håkansson K

    更新日期：1996-04-01 00:00:00

  • Purification and partial characterization of coxsackievirus B3 2A protease expressed in Escherichia coli.

    abstract：:Reported here is the overexpression, purification and partial characterization of recombinant coxsakievirus B3 2A protease (CVB3 2Apro) from bacterial cells transformed with a plasmid containing the CVB3 2Apro cDNA sequences. The structural investigation showed that the protein contains mostly beta-strand elements and...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2008.05.008

    authors： Maghsoudi N,Khodagholi F,Sadjadi M,Zeinodini M,Sabbaghian M

    更新日期：2008-10-01 00:00:00

  • Development of composite hydrogel based on hydroxyapatite mineralization over pectin reinforced with cellulose nanocrystal.

    abstract：:Hydrogels based on pectin and cellulose nanocrystals (CNC) were used in our study to nucleation and growth of hydroxyapatite (HAp) by the biomimetic method. In this study, we evaluated the direct impact of the different percentages of CNC on pectin hydrogel and the influence of HAp obtained through two methods. CNC we...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.12.012

    authors： Catori DM,Fragal EH,Messias I,Garcia FP,Nakamura CV,Rubira AF

    更新日期：2021-01-15 00:00:00

  • Polysaccharides and proteins-based nanogenerator for energy harvesting and sensing: A review.

    abstract：:Nanogenerator is a promising energy harvesting device that can scavenge tiny mechanical energy from the surrounding environment, and then convert it into electricity. Natural bio-polymers are the potential candidates for the design of nanogenerators due to their excellent characteristics like piezoelectricity, triboel...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2021.01.109

    authors： Cao L,Qiu X,Jiao Q,Zhao P,Li J,Wei Y

    更新日期：2021-01-20 00:00:00

  • Understanding the adhesion mechanism of a mucin binding domain from Lactobacillus fermentum and its role in enteropathogen exclusion.

    abstract：:Lactobacillus species possesses surface exposed Mucin Binding Protein (MucBP) which plays a role in adhesion to gastrointestinal mucin. MucBP contains one or more mucin binding domain (MBD), the functionality of which has yet not been characterized thoroughly. Here, we have characterized a 93-amino acid MBD (MBD93) of...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.10.107

    authors： Chatterjee M,Pushkaran AC,Vasudevan AK,Menon KKN,Biswas R,Mohan CG

    更新日期：2018-04-15 00:00:00

  • Overexpression of secreted sucrose isomerase in Yarrowia lipolytica and its application in isomaltulose production after immobilization.

    abstract：:Isomaltulose production by bacterial fermentation was limited, due to generation of undesirable products and reduced yields. Isomaltulose production using sucrose isomerase (SIase) catalyzed methods was expected to be more applicable, but was hampered by low SIase activity and lack of a secreted SIase producer. Here, ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.10.010

    authors： Zhang P,Wang ZP,Liu S,Wang YL,Zhang ZF,Liu XM,Du YM,Yuan XL

    更新日期：2019-01-01 00:00:00

  • Characterization of a novel exopolysaccharide produced by Lactobacillus gasseri FR4 and demonstration of its in vitro biological properties.

    abstract：:In this study, hetero-exopolysaccharide of Lactobacillus gasseri FR4 isolated from native chicken was produced and purified. The molecular weight of LgEPS was found to be 1.86×105Da. The gas chromatographic analysis revealed that the LgEPS was majorly composed of glucose (65.31%), mannose (16.51%), galactose (8.45%), ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.11.062

    authors： Rani RP,Anandharaj M,David Ravindran A

    更新日期：2018-04-01 00:00:00

  • Oriented covalent immobilization of recombinant protein A on the glutaraldehyde activated agarose support.

    abstract：:High IgG-binding capacity of protein A affinity chromatography is crucial to its application in the antibody purification and autoantibody-associated disease treatment. An oriented immobilization strategy was used to covalently conjugate the recombinant protein A (rSpA) on the glutaraldehyde activated agarose. By cont...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.074

    authors： Wang Y,Zhang X,Han N,Wu Y,Wei D

    更新日期：2018-12-01 00:00:00

  • Amphiphilic graft copolymeric micelle using dextrin and poly (N-vinyl caprolactam) via RAFT polymerization: Development and application.

    abstract：:Dextrin and poly (N-vinyl caprolactam) based amphiphilic graft copolymer has recently been developed using RAFT polymerization. The prepared graft copolymer has been characterized in details using FTIR and 1H NMR spectral analyses, GPC, TGA, FESEM, TEM and DLS analyses. GPC analysis results indicate that the polymeriz...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.07.198

    authors： Pal A,Sarkar AN,Karmakar PD,Pal S

    更新日期：2018-11-01 00:00:00

  • Solubility and rheological behavior of silk fibroin (Bombyx mori) in N-methyl morpholine N-oxide.

    abstract：:As an important direct solvent for cellulose, N-methyl morpholine N-oxide (NMMO) is environmentally friendly, and potentially very economical. Silk fibroin (SF) (Bombyx mori) can also be dissolved directly in NMMO.H2O. However, it is unexpectedly difficult to obtain a silk fibroin solution with a concentration higher ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2004.11.008

    authors： Xu Y,Zhang Y,Shao H,Hu X

    更新日期：2005-04-01 00:00:00

  • Isolation and structural characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its arrest of cell cycle at S-phage in colon cancer cells.

    abstract：:The fruiting body of Hericium erinaceus has been used to treat digestive system disorder-related diseases for over 2000 years in China. A novel polysaccharide, HEFP-2b, was obtained from H. erinaceus fruiting bodies. Physical and chemical analysis showed that HEFP-2b consisted of fucose, galactose, glucose, and mannos...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.162

    authors： Liu JY,Hou XX,Li ZY,Shan SH,Chang MC,Feng CP,Wei Y

    更新日期：2020-08-15 00:00:00

  • Thermo-sensitive chitosan copolymer-gold hybrid nanoparticles as a nanocarrier for delivery of erlotinib.

    abstract：:Here, using (poly(N-isopropylacrylamide)-co-oleic acid)-g-chitosan ((PNIPAAm-co-OA)-g-CS), CS copolymer-gold hybrid nanoparticles (CGH NPs) were synthesized by autoreduction of auric cations (HAuCl4) in aqueous solution in the absence of any other reducing agent. The engineered thermo-sensitive CS copolymer with free ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.08.020

    authors： Fathi M,Sahandi Zangabad P,Barar J,Aghanejad A,Erfan-Niya H,Omidi Y

    更新日期：2018-01-01 00:00:00

  • Using pullulan-based edible coatings to extend shelf-life of fresh-cut 'Fuji' apples.

    abstract：:Pullulan is a thickener that can form semipermeable films, and glutathione is an effective reducing agent, while chitooligosaccharide has antibacterial activity. In this study, effect of pullulan-based coatings in combination with antibrowning and antibacterial agents (1% pullulan; 0.8% glutathione+1% chitooligosaccha...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.01.012

    authors： Wu S,Chen J

    更新日期：2013-04-01 00:00:00

  • Antitumor activity of polysaccharides from Lepista sordida against laryngocarcinoma in vitro and in vivo.

    abstract：:Four water-soluble polysaccharides (LSPa1, LSPb1, LSPb2 and LSPc1) extracted from the fruiting bodies of Lepista sordida were prepared by DEAE cellulose-52 anion-exchange and Sepharose 6 Fast Flow gel-permeation chromatography. LSPa1 was composed of Glc, Man and Gal with a molar ratio of 3.2: 1.3: 0.6. LSPb1, LSPb2 an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.05.033

    authors： Miao S,Mao X,Pei R,Miao S,Xiang C,Lv Y,Yang X,Sun J,Jia S,Liu Y

    更新日期：2013-09-01 00:00:00

  • Computational study of the conformational profiles of model bis-cystine cyclic peptides.

    abstract：:Bis-cystine cyclic peptides are a new kind of molecules with potential use as cavitands, transporters or antagonists of target ligands. Studies aimed at establishing their conformational profiles may prove useful in understanding their characteristics and potentiate their use in molecular design. The present investiga...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(95)01083-1

    authors： Fernandez Y,Ricart JM,Perez JJ

    更新日期：1996-06-01 00:00:00

  • Influence of the method of purification on some solution properties of welan gum.

    abstract：:The origin and some consequences of the presence of aggregates and impurities (deriving from the fermentation procedure) on the solution properties of welan gum have been studied. For this purpose, a method of purification was developed for a fermentation welan broth. It was verified that this method is ineffective fo...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(94)90030-2

    authors： Lopes L,Milas M,Rinaudo M

    更新日期：1994-10-01 00:00:00

  • Purification and characterization of two polyhydroxyalcanoates from Bacillus cereus.

    abstract：:This work aimed to study the potential of 155 strains of Bacillus sp., isolated from a collection of Tunisian microorganisms, for polyhydroxyalcanoates production. The strains were submitted to a battery of standard tests commonly used for determining bioplastic properties. The findings revealed that two of the isolat...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.06.043

    authors： Zribi-Maaloul E,Trabelsi I,Elleuch L,Chouayekh H,Ben Salah R

    更新日期：2013-10-01 00:00:00

  • Effect of duration of sonication during gelatinization on properties of tapioca starch water hyacinth fiber biocomposite.

    abstract：:This paper characterizes properties of biocomposite sonicated during gelatinization. The biocomposite consisted of tapioca starch based plastic reinforced by 10% volume fraction of water hyacinth fiber (WHF). During gelatinization, the biocomposite was poured into a rectangular glass mold then vibrated in an ultrasoni...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.11.165

    authors： Asrofi M,Abral H,Putra YK,Sapuan SM,Kim HJ

    更新日期：2018-03-01 00:00:00

  • Synthesis and characterization of diethoxy phosphoryl chitosan.

    abstract：:A novel diethoxy phosphoryl chitosan was successfully synthesized via Atherton-Todd reaction of chitosan with diethyl phosphite, and the characterization was carried out by FT IR, NMR, ICP, XRD, TG and SEM, respectively. The FT IR, (13)C NMR and (31)P NMR results showed that diethoxy phosphoryl group was grafted onto ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2010.06.014

    authors： Ma L,Li G,Li L,Liu P

    更新日期：2010-11-01 00:00:00