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In situ preparation of glycoconjugate hollow microspheres mimics the extracellular matrix via interfacial polymerization.

Abstract：

:A novel chitin-graft-polyleucine microsphere with hollow construction was prepared via ring-opening polymerization initiated with chitin based on interfacial protocol. The FT-IR and (1)H NMR analysis demonstrated the conjugation with regulated graft length. The study provided a facile one-step route to obtain microsphere with glycoconjugation structure. This hybrid polysaccharide-polypeptide microsphere may give promising application in drug delivery and tissue engineering.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Wang J,Liu C,Chi P

doi

10.1016/j.ijbiomac.2008.02.007

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

450-4

issue

5

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(08)00051-2

journal_volume

42

pub_type

杂志文章

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