Abstract:
:Lipids extracted from Halocynthia roretzi contain n-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid, as well as carotenoids. The aim of the present study was to evaluate the effect of H. roretzi lipids on white adipose tissue (WAT) weight and high blood glucose levels in diabetic/obese KK-Ay mice. H. roretzi lipids were fed to the diabetic/obese KK-Ay mice for 5 weeks. In the mice treated with the H. roretzi lipids compared to control mice, WAT weight was reduced, blood glucose levels and leptin mRNA expression in the epididymal WAT were significantly decreased, serum leptin levels also tended to decrease, and serum adiponectin levels tended to increase. These results demonstrate that H. roretzi lipids have beneficial health effects on diabetic/obese KK-Ay mice.
journal_name
Mol Med Repjournal_title
Molecular medicine reportsauthors
Mikami N,Hosokawa M,Miyashita Kdoi
10.3892/mmr_00000278subject
Has Abstractpub_date
2010-05-01 00:00:00pages
449-53issue
3eissn
1791-2997issn
1791-3004journal_volume
3pub_type
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