Abstract:
:Aim. To evaluate whether body fat distribution, birth weight, and family history for diabetes (FHD) were associated with metabolic syndrome (MetS) in children and adolescents. Methods. A total of 439 Italian obese children and adolescents (5-18 years) were enrolled. Subjects were divided into 2 groups: prepubertal and pubertal. MetS was diagnosed according to the adapted National Cholesterol Education Program criteria. Birth weight percentile, central obesity index (measured by dual-energy X-ray absorptiometry), insulin sensitivity (ISI), and disposition index were evaluated. Multivariate logistic regression models were used to determine variables associated with MetS. Results. The prevalence of MetS was 17%, with higher percentage in adolescents than in children (21 versus 12%). In the overall population, central obesity index was a stronger predictor of MetS than insulin sensitivity and low birth weight. When the two groups were considered, central fat depot remained the strongest predictor of MetS, with ISI similarly influencing the probability of MetS in the two groups and birth weight being negatively associated to MetS only in pubertal individuals. Neither FHD nor degree of fatness was a significant predictor of MetS. Conclusion. Simple clinical parameters like increased abdominal adiposity and low birth weight could be useful tools to identify European obese adolescents at risk for metabolic complications.
journal_name
Int J Hypertensjournal_title
International journal of hypertensionauthors
Brufani C,Fintini D,Giordano U,Tozzi AE,Barbetti F,Cappa Mdoi
10.4061/2011/257168subject
Has Abstractpub_date
2011-02-22 00:00:00pages
257168eissn
2090-0384issn
2090-0392journal_volume
2011pub_type
杂志文章abstract::Organic nitrates are a group of very effective anti-ischemic drugs. They are used for the treatment of patients with stable angina, acute myocardial infarction, and chronic congestive heart failure. A major therapeutic limitation inherent to organic nitrates is the development of tolerance, which occurs during chronic...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/842632
更新日期:2012-01-01 00:00:00
abstract::Great efforts to advance the diagnosis and treatment of hypertension for controlling hypertension have been made; however, the rates of uncontrolled blood pressure are still high. This study explored the rate of uncontrolled hypertension in patients with hypertension managed in an urban hospital of Vietnam and identif...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/5710281
更新日期:2020-09-10 00:00:00
abstract:Objective:There is poor adherence to antihypertensive therapies among women in India. To determine its socioeconomic barriers we performed a qualitative study on Indian rural women with hypertension. Methods:In-depth interviews with women having hypertension and presenting to outpatient department at a teaching hospit...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/5749648
更新日期:2019-01-23 00:00:00
abstract::Background. Effective antihypertensive treatment depends on patient compliance regarding prescribed medications. We assessed the impact of beliefs related towards antihypertensive medication on blood pressure control in a population-based sample treated for hypertension. Methods. We used data from the Characteristics ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/9385397
更新日期:2019-07-28 00:00:00
abstract::Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the researches in recent years, myocardial fibrosis, as the pathological basis of various cardiovascular diseases, has been proven to be a co...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2020/3014693
更新日期:2020-01-31 00:00:00
abstract::We investigated the relationship between renal function, blood pressure variability (BPV), and nitric oxide (NO) in a group of African Americans with normal or mildly impaired renal function. 24-hour ambulatory blood pressure monitoring was performed, NO measured, and glomerular filtration rate (GFR) calculated in 38 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/137206
更新日期:2011-01-09 00:00:00
abstract::Angiotensin II increases blood pressure and stimulates thirst and sodium appetite in the brain. It also stimulates secretion of aldosterone from the adrenal zona glomerulosa and epinephrine from the adrenal medulla. The rat has 3 subtypes of angiotensin II receptors: AT1a, AT1b, and AT2. mRNAs for all three subtypes o...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/175428
更新日期:2013-01-01 00:00:00
abstract::Accumulating evidence from animal models and human studies of essential hypertension suggest that brain regulation of the vasculature is impacted by the disease. Human neuroimaging findings suggest that the brain may be an early target of the disease. This observation reinforces earlier research suggesting that psycho...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/701385
更新日期:2012-01-01 00:00:00
abstract::This study aimed to determine the prevalence of Self-Monitoring Blood Pressure amongst people with hypertension using a cross-sectional survey. Of the 955 who replied (53%), 293 (31%) reported that they self-monitored blood pressure. Nearly 60% (198/331) self-monitored at least monthly. Diabetic patients monitoring th...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/582068
更新日期:2012-01-01 00:00:00
abstract:Background:Epoxide hydrolase 2 (EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of hypertension. Objectives:We aimed to assess the association of a missense mutation, R287Q, in EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2351547
更新日期:2020-02-28 00:00:00
abstract:Objectives:Prevalence of hypertension has not been studied in the Ethiopian HIV-infected population, which represents 60% of the patients in our AIDS unit. Our aim was to identify risk factors and characterize the prevalence of hypertension in the population monitored at our unit. Methods:A retrospective chart review ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8637101
更新日期:2018-01-29 00:00:00
abstract::Primary aldosteronism is a main cause of secondary hypertension which can be effectively treated. The screening test for primary aldosteronism is benefit for minimizing damage to the patient. In the previous retrospective study, we obtained the optimal cutoff value of aldosterone-to-renin ratio detected by chemilumine...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/3934212
更新日期:2020-08-27 00:00:00
abstract::The human renin gene has been widely known to be involved in essential hypertension (EH) pathogenesis. Genetic variant C-5434T of REN enhancer contributed to renin gene transcription and serum renin regulation. However, the mechanism associated with the transcription level changes remains unknown, and only a few repor...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2015/486961
更新日期:2015-01-01 00:00:00
abstract::In 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025 subjects from the ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/951734
更新日期:2012-01-01 00:00:00
abstract::The distribution of the T29C TGFβ1 gene polymorphism was analyzed in 198 hypertensives with left ventricular hypertrophy (LVH) and in 235 hypertensives without LVH. Circulating TGFβ1 levels, procollagen type III levels, microalbuminuria, and left ventricular geometry and function were evaluated in all the hypertensive...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/647147
更新日期:2010-03-23 00:00:00
abstract::The spontaneously hypertensive rat model with reduced NO synthesis (SHRLN) shares features with aging and hypertension in humans, among other a severe aortic stiffening. The present in vivo study aimed to compare thoracic (TA) and abdominal (AA) aortic stiffness in the SHRLN (treated 5 weeks with L-NAME), SHR, and nor...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/8070198
更新日期:2019-03-19 00:00:00
abstract::Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and centra...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2015/742658
更新日期:2015-01-01 00:00:00
abstract::Sodium transport through various nephron segments is quite important in regulating sodium reabsorption and blood pressure. Among several regulators of this process, insulin acts on almost all the nephron segments and is a strong enhancer of sodium reabsorption. Sodium-proton exchanger type 3 (NHE3) is a main regulator...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/391762
更新日期:2011-01-01 00:00:00
abstract:Background:Hypertension is a major cardiovascular risk factor that is linked with fatal complications and is an overwhelming global challenge. Primary prevention is a key to control hypertension with identification of major risk factors. This study was aimed at assessing the prevalence and factors associated with hyper...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/9878437
更新日期:2019-05-15 00:00:00
abstract:Background:Hypertension remains a cause of morbidity and mortality in the Ashanti Region of Ghana. It has been featured in the top ten causes of OPD attendance, admissions, and deaths since 2012. We investigated the sociodemographic characteristics and spatial distribution of inpatient hypertensives and factors associa...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2017/6537956
更新日期:2017-01-01 00:00:00
abstract::The brain renin-angiotensin system (RAS) has been highlighted as having a pathological role in stroke, dementia, and neurodegenerative disease. Particularly, in dementia, epidemiological studies indicate a preventive effect of RAS blockade on cognitive impairment in Alzheimer disease (AD). Moreover, basic experiments ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/169649
更新日期:2012-01-01 00:00:00
abstract::Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of a...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8163824
更新日期:2018-09-18 00:00:00
abstract::Background. Developing interventions to improve medication adherence may depend upon discovery of novel behavioral risk factors for nonadherence. Objective. Explore the effects of emotional response (ER) on adherence to antihypertensive medication and on systolic blood pressure (SBP) improvement. Design. We studied 10...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/358562
更新日期:2013-01-01 00:00:00
abstract::Objectives. To determine the changes in blood pressure levels and antihypertensive medication use in the postrenal transplantation period compared to pretransplantation one. Methods. A comparative cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital, a national referra...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2016/8450596
更新日期:2016-01-01 00:00:00
abstract::Sympathetic activation in chronic renal failure (CRF) is a major mechanism leading to the progression of renal disease and hypertension. In the present study, we tested the hypothesis that in CRF increased reactive oxygen species (ROS) production in the RVLM mediated by enhanced circulating Angiotensin II (Ang II) is ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/219358
更新日期:2011-01-04 00:00:00
abstract::Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents in Germany in the context of hypertension risk factors. BP was measured and analyzed in 2542 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8429891
更新日期:2018-09-26 00:00:00
abstract::Introduction. Dahl salt-resistant (SR) animal models are similar to peritoneal dialysis patients with fluid volumes overload with normal blood pressure in hemodynamic profiles. We will verify the roles of UII in the regulation of blood pressure in these animal models. Methodology. The Dahl salt-sensitive (SS) and SR r...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2016/9146870
更新日期:2016-01-01 00:00:00
abstract::Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asymptomatic hypertensive ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/478710
更新日期:2011-01-01 00:00:00
abstract:Background:Angiopoietin-like protein 3 (ANGPTL3) plays a pivotal role in lipid metabolism and angiogenesis, and there is growing interest regarding the association between ANGPTL3 and coronary artery disease (CAD). This study aims to investigate whether ANGPTL3 levels can be used to predict the future occurrence of maj...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2980954
更新日期:2020-03-27 00:00:00
abstract:Purpose:To compare several anthropometric indices in the prediction of hypertension among adults. Methods:This is a cross-sectional study. Five hundred and eighteen adult men and women (40.9 ± 10.5 years; 1.62 ± .09 m; 72.3 ± 15.6 kg) volunteered to participate and underwent blood pressure and anthropometric measures....
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8396570
更新日期:2018-06-05 00:00:00