Establishment of a poisoned animal model of toxic encephalopathy induced by 1,2-dichloroethane.

abstract：:More and more studies have demonstrated the anti-inflammatory effects of heparin. However, in the aspect of allergic airway inflammation, data about its daily use in animal model is scarce. To evaluate the efficacy of 22-day intranasal heparin administration in mite-induced airway allergic inflammation in BALB/c mice,...

journal_title：International journal of immunopathology and pharmacology

authors： Fu LS,Tsai JJ,Chen YJ,Lin HK,Tsai MC,Chang MD

更新日期：2013-04-01 00:00:00

abstract：:Cyclosporine A (CsA) has been in clinical use for some decades, primarily for the prevention and treatment of organ transplant rejection and graft-versus-host disease. In more recent years, Cyclosporine has been recognized as beneficial in the treatment of dermatologic diseases, such as: psoriasis, lichen planus, Behc...

journal_title：International journal of immunopathology and pharmacology

authors： Feliciani C,Tulli A

更新日期：2002-05-01 00:00:00

abstract：:Blockade of the interactions between CD28/CTLA-4 and their ligands, CD80 (B7, B7.1)/CD86 (B70, B7.2), is an attractive means to induce antigen-specific peripheral tolerance in autoimmune disease and organ transplantation. In this study, we generated and characterized a monoclonal antibody (Clone 4E5) against human CD8...

journal_title：International journal of immunopathology and pharmacology

authors： Shi Q,Gao ZY,Xie F,Wang LF,Gu YP,Yang TJ,Huang L,Qian QH,Qiu YH

更新日期：2011-07-01 00:00:00

abstract：:Biological and technical failures of implants have already been reported. Mechanical factors are certainly of importance in implant failures, even if their exact nature has not yet been established. The abutment screw fracture or loosening represents a rare, but quite unpleasant failure. The aim of the present researc...

journal_title：International journal of immunopathology and pharmacology

authors： Scarano A,Murmura G,Sinjiari B,Sollazzo V,Spinelli G,Carinci F

更新日期：2011-04-01 00:00:00

abstract：:Capsular contracture is a highly distressing, difficult complication after breast augmentation for both the patient and the surgeon. Although capsular contracture is a multifactorial process, one common denominator in the successful treatment of this complication is believed to be the abatement of inflammation. Leukot...

journal_title：International journal of immunopathology and pharmacology

authors： Scuderi N,Mazzocchi M,Rubino C

更新日期：2007-07-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective effects of diallyl trisulfide (DATS) against naphthalene-induced oxidative and inflammatory damage in the livers and lungs of mice. Elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels showed significant hepatic damag...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang F,Zhang Y,Wang K,Liu G,Yang M,Zhao Z,Li S,Cai J,Cao J

更新日期：2016-06-01 00:00:00

abstract：:Antimuscarinic drugs are the first line pharmacotherapy for overactive bladder, but they are not always effective to achieve complete continence. Nevertheless in some patients urodynamic investigations reveal insufficient effects with continuing incontinence events even with dose optimization. The aim of this study is...

journal_title：International journal of immunopathology and pharmacology

authors： Nardulli R,Losavio E,Ranieri M,Fiore P,Megna G,Bellomo RG,Cristella G,Megna M

更新日期：2012-01-01 00:00:00

abstract：:Polysensitization is a feature of allergic rhinitis (AR) that significantly impairs the quality of life (QoL) of AR patients. Allergen-specific immunotherapy is the only causal therapy for AR. However, the polysensitization phenomenon may represent a crucial obstacle as far as it concerns the choice of the allergen ex...

journal_title：International journal of immunopathology and pharmacology

authors： Ciprandi G,Incorvaia C,Puccinelli P,Scurati S,Masieri S,Frati F

更新日期：2010-04-01 00:00:00

abstract：:It is of significance to alleviate oxidative damages for the treatment of spinal cord injury (SCI). Studies have ascertained that green tea polyphenols (GTPs) exert protective activities against oxidative damages. In this study, we aimed to investigate the protective effects of GTP against H2O2-caused injuries in PC12...

journal_title：International journal of immunopathology and pharmacology

authors： Liu S,Yu G,Song G,Zhang Q

更新日期：2019-01-01 00:00:00

abstract：:Ticks are obligate hematophagous arthropods that are parasites in every class of vertebrates in most regions of the world. They are also considered to be important vectors for the transmission of human infectious diseases. In the present study we used polymer chain reaction (PCR) amplification analysis to determine th...

journal_title：International journal of immunopathology and pharmacology

authors： Santino I,Iori A,Nicoletti M,Valletta S,Cimmino C,Scoarughi GL,Santapaola D,Sessa R,Del Piano M

更新日期：2003-05-01 00:00:00

abstract：:Fibroblasts play a key role in tissue healing by producing the majority of extracellular matrix components, favouring granulation tissue formation, and stimulating re-epithelialization. Hyaluronan is a component of ECM and its anti-inflammatory effects and properties in enhancing wound closure are well known. In this ...

journal_title：International journal of immunopathology and pharmacology

authors： Mariggiò MA,Cassano A,Vinella A,Vincenti A,Fumarulo R,Lo Muzio L,Maiorano E,Ribatti D,Favia G

更新日期：2009-04-01 00:00:00

abstract：:Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its s...

journal_title：International journal of immunopathology and pharmacology

authors： Castellani ML,Felaco P,Galzio RJ,Tripodi D,Toniato E,De Lutiis MA,Fulcheri M,Caraffa A,Antinolfi P,Tetè S,Felaco M,Conti F,Pandolfi F,Theoharides TC,Shaik-Dasthagirisaheb YB

更新日期：2010-07-01 00:00:00

abstract：:Few studies have evaluated the occurrence of immediate adverse reactions in allergic patients after an ultra-rush regimen of different commercial allergen extracts for sublingual immunotherapy (SLIT) Methods: 679 patients took part in trials of specific ultra-rush SLIT for the treatment of IgE-mediated rhinitis and/or...

journal_title：International journal of immunopathology and pharmacology

authors： Rossi RE,Monasterolo G

更新日期：2005-04-01 00:00:00

abstract：:Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...

journal_title：International journal of immunopathology and pharmacology

authors： Carmignani M,Felaco M,Boscolo P,Di Gioacchino M,Di Giampaolo L,Niu Q,Cesare P,Volpe AR

更新日期：2004-05-01 00:00:00

abstract：:Salmonellosis-induced diarrhea, is one of the commonest cause of childhood mortality in developing countries. Using of probiotics is viewed as a promising means for reducing the pathogenic loads of bacterial infection. The current study aimed to evaluate the potential antimicrobial and immunomodulatory efficacy of iso...

journal_title：International journal of immunopathology and pharmacology

authors： Mazaya B,Hamzawy MA,Khalil MA,Tawkol WM,Sabit H

更新日期：2015-12-01 00:00:00

abstract：:We aimed to analyze the action of berberine on the neuropathic pain and neuroglia activation in experimental diabetes mellitus (DM) model. Diabetes in mice was induced by intraperitoneal injection of streptozotocin (STZ) followed by the administration of berberine. Mechanical allodynia and thermal hyperalgesia and act...

journal_title：International journal of immunopathology and pharmacology

authors： Liu M,Gao L,Zhang N

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...

journal_title：International journal of immunopathology and pharmacology

authors： Jiang X,Li X,Zheng S,Du G,Ma J,Zhang L,Wang H,Tian J

更新日期：2020-01-01 00:00:00

abstract：:United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persis...

journal_title：International journal of immunopathology and pharmacology

authors： Profita M,Montuschi P,Bonanno A,Riccobono L,Montalbano AM,Ciabattoni G,Albano GD,Liotta G,Bousquet J,Gjomarkaj M,La Grutta S

更新日期：2010-10-01 00:00:00

abstract：:Multiple sclerosis (MS) is thought to be an autoimmune T-cell-mediated disease directed at myelin antigens of the central nervous system. Besides myelin proteins, lipid components of CNS are supposed to play a role as antigens for T cells in MS. CD1 is a family of MHC-like glycoproteins specialized in capturing and pr...

journal_title：International journal of immunopathology and pharmacology

authors： Caporale CM,Notturno F,Pace M,Aureli A,Di Tommaso V,De Luca G,Farina D,Giovannini A,Uncini A

更新日期：2011-01-01 00:00:00

abstract：:Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development o...

journal_title：International journal of immunopathology and pharmacology

authors： Mastrangelo F,Piccirilli M,Dolci M,Teté S,Speranza L,Patruno A,Gizzi F,Felaco M,Artese L,De Lutiis MA

更新日期：2005-07-01 00:00:00

abstract：:After birth various bacterial species, mainly streptococci, colonize the oral cavity and are frequently isolated from carious lesions in children. Previous studies suggest that an earlier colonization of a child's mouth by cariogenic organisms might be related to a higher risk of caries. The aim of this study is to as...

journal_title：International journal of immunopathology and pharmacology

authors： Duse M,Zicari AM,Berlutti F,Ernesti I,Occasi F,Leonardi L,Polimeni A

更新日期：2014-01-01 00:00:00

abstract：:In order to understand the immunogenicity of a tumor-associated antigen (TAA), Ras family small GTP binding protein (Ra1A) in hepatocellular carcinoma (HCC), autoantibody responses to RalA were evaluated by enzyme-linked immunosorbent assay (ELISA), Western blotting and indirect immunofluorescence assay in sera from p...

journal_title：International journal of immunopathology and pharmacology

authors： Wang K,Chen Y,Liu S,Qiu S,Gao S,Huang X,Zhang J,Peng X,Qiani W,Zhang JY

更新日期：2009-07-01 00:00:00

abstract：:Serum samples from Bulgarian patients with physician-diagnosed erythema migrans (EM) (n=105) were examined using Borrelia burgdorferi ELISA (Boehring, Germany) after previous absorption with Treponema phagedenis. For IgM antibody detection sera were additionally pretreated with anti-IgG serum (RF absorbent). Serum sam...

journal_title：International journal of immunopathology and pharmacology

authors： Christova I

更新日期：2003-09-01 00:00:00

abstract：:Interleukin (IL)-8 is a major factor in inflammatory response and the IL-8 levels in exhaled breath condensate (EBC) may be used as a marker of airway inflammation. Airway acidification is implicated in the pathophysiology of obstructive airway diseases and pH EBC values have been used as a marker of airway acidificat...

journal_title：International journal of immunopathology and pharmacology

authors： Bodini A,D'Orazio C,Peroni DG,Corradi M,Zerman L,Folesani G,Assael BM,Boner AL,Piacentini GL

更新日期：2007-07-01 00:00:00

abstract：:We examined the expression of human leukocyte antigen (HLA) and composition of differentiated T cells in the peripheral blood to understand the characteristics of the immune changes in patients with adult-onset Still's disease (AOSD). This study enrolled patients with AOSD (n = 14), patients with rheumatoid arthritis ...

journal_title：International journal of immunopathology and pharmacology

authors： Jung JY,Choi B,Sayeed HM,Suh CH,Kim YW,Kim HA,Sohn S

更新日期：2018-01-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and treatment involves antibiotics, mucoactive agents, and airway clearance techniques (ACTs). Traditional ACTs have four components: postural draina...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Fernandez Dominguez B,Calgaro S,Bertozzi I,Escribano Montaner A,Perilongo G,Barbato A

更新日期：2015-06-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:It is well known that change in apoptosis may modulate the natural story of illness, and that many drugs may act through modulation of apoptosis, but the role of steroids in acting through apoptosis in different settings, including renal diseases, has still to be elucidated. We studied the in vivo effects of steroids ...

journal_title：International journal of immunopathology and pharmacology

authors： Stratta P,Canavese C,Fenoglio R,Priolo G,Grillo A,Aimo G,Quaglia M,Pagni R

更新日期：2006-07-01 00:00:00

abstract：:Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by a progressive cognitive and memory decline. Among peripheral markers of AD, great interest has been focused on the amyloid precursor protein (APP). In this regard, platelets represent an important peripheral source of APP since it has be...

journal_title：International journal of immunopathology and pharmacology

authors： Vignini A,Sartini D,Morganti S,Nanetti L,Luzzi S,Provinciali L,Mazzanti L,Emanuelli M

更新日期：2011-04-01 00:00:00

abstract：:HSP60 has been implicated in chronic inflammatory disease pathogenesis, including chronic obstructive pulmonary disease (COPD), but the mechanisms by which this chaperonin would act are poorly understood. A number of studies suggest a role for extracellular HSP60, since it can be secreted from cells and bind Toll-like...

journal_title：International journal of immunopathology and pharmacology

authors： Sangiorgi C,Vallese D,Gnemmi I,Bucchieri F,Balbi B,Brun P,Leone A,Giordano A,Conway de Macario E,Macario AJ,Cappello F,Di Stefano A

更新日期：2017-12-01 00:00:00