Abstract：
:Malaria, caused by parasites of the genus Plasmodium, is one of the leading infectious diseases in many tropical regions, including Nigeria, a West African country where transmission occurs all year round. Many of the inhabitants use plants as remedies against fever and other symptoms of acute malaria, as reported herein. Some of these plants have their antimalarial efficacies scientifically demonstrated and the active compounds isolated with their probable mechanisms of action studied. Medicinal plants are used to treat diseases also where the biodiversity of plants occur in parallel with endemic transmission of malaria. This review focuses on medicinal plants which are used to treat malaria in Nigeria, and on antimalarial testing of extracts and purified compounds from plants. Some show intense activity against malaria parasites in vitro and in experimentally infected mice. The search for new drugs based on plants is important due to the emergence and widespread of chloroquine-resistant and multiple drug-resistant malaria parasites, which require the development of new antimalarials. An acquaintance with antimalarial plants may be a springboard for new phytotherapies that could be affordable to treat malaria, especially among the less privileged native people living in endemic areas of the tropics, mostly at risk of this devastating disease.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Adebayo JO,Krettli AUdoi
10.1016/j.jep.2010.11.024subject
Has Abstractpub_date
2011-01-27 00:00:00pages
289-302issue
2eissn
0378-8741issn
1872-7573pii
S0378-8741(10)00809-3journal_volume
133pub_type
杂志文章,评审abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sanmiao wan (SMW) is widely used for the treatment of gout and hyperuricemia in traditional Chinese medicine. AIM OF THE STUDY:The aim of the present study was to investigate the hypouricemic effects of SMW and its possible mechanism in potassium oxonate-induced hyperuricemic mice. MATE...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.12.035
更新日期：2010-03-02 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Saussurea involucrate (Kar. et Kir.) Sch. -Bip is an endangered species of the Compositae family, and this species has long been used for the treatment of rheumatoid arthritis, dysmenorrhea, stomachache, and altitude sickness in Uighur folk and Chinese medicine. AIM OF THE STUDY:This stu...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2016.09.008
更新日期：2016-12-24 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The rhizomes of Boesenbergia longiflora (Wall.) Kuntze (Zingiberaceae) have been traditionally used for treatment of inflammatory bowel disease, ulcerative colitis, aphthous ulcer and abscess by decoction with alcohol. AIM OF THE STUDY:The rhizomes of Boesenbergia longiflora were carried...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.08.038
更新日期：2013-10-28 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Most cardiovascular diseases ultimately result in heart failure, an intractable problem in modern medicine. Yangxinshi tablet (YXS) is a Chinese medicine formula that is used clinically to treat coronary heart disease. However, the active compounds, potential targets, and pharmacological ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112227
更新日期：2020-01-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Jiao-Tai-Wan (JTW), an important herbal formula consists of Rhizoma coptidis and Cortex cinnamomi powder, is a famous prescription which has been used for centuries to treat insomnia in Traditional Chinese Medicine. The purpose of this study is to compare the pharmacokinetic properties of...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.04.040
更新日期：2014-07-03 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Melicope lunu-ankenda leaves are used to treat diabetes in folklore medicinal practices in India and Malaysia. Here we report the isolation of an O-prenylated flavonoid (3,5,4'-trihydroxy-8,3'-dimethoxy-7-(3-methylbut-2-enoxy)flavone; OPF) from the leaves of M. lunu-ankenda and its antidi...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.03.060
更新日期：2015-06-20 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Laurus nobilis L. (Lauraceae) has been used for folk medicines in the Mediterranean area and Europe to treat various disorders including skin inflammation (dermatitis) and asthma. AIM OF THE STUDY:Our aim was to investigate the scientific evaluation of the compounds from Laurus nobilis L...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.07.015
更新日期：2013-09-16 00:00:00
abstract：:Traditional livestock healers from Samburu and Turkana communities in Samburu District of Kenya were identified and recruited for participation in this study. Sheep with mixed gastrointestinal helminthosis were purchased from nomadic livestock owners in the area. Three herbal anthelmintic remedies, viz. Myrsine africa...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2003.11.007
更新日期：2004-03-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tetrastigma hemsleyanum Diels et Gilg, known as Sanyeqing in China, was an extensively used folk Chinese herbal medicine. This plant had been validated to be highly effective for treating high fever, pneumonia, hepatitis, gastritis, cervicitis, lymphatic tuberculosis, septicemia, and vira...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2021.113836
更新日期：2021-01-16 00:00:00
abstract：AIM OF THE STUDY:Evaluations of the anti-snake venom efficacy of Mimosa pudica tannin isolate (MPT) obtained from root of the plant. MATERIALS AND METHOD:MPT was investigated in vitro and in vivo for its efficacy against the venom of Naja kaouthia snake. RESULTS:In vitro: (1) mice injected i.p. with MPT pre-incubated...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.05.013
更新日期：2011-09-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Xiao-Xu-Ming decoction (XXMD) has long been employed clinically to treat stroke in traditional Chinese Medicine. AIM OF THE STUDY:To investigate the neuroprotective effects of XXMD in vivo and in vitro stroke models and determine involved mechanisms. MATERIALS AND METHODS:Two models (fo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.09.054
更新日期：2010-01-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Casearia sylvestris Sw. is widely used in popular medicine to treat inflammatory conditions. AIM OF THE STUDY:To investigate the anti-inflammatory and antioxidant properties of hydroalcoholic crude extract (HCE) taken from Casearia sylvestris Sw. (Salicaceae). METHODS AND RESULTS:The ef...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.03.049
更新日期：2013-06-03 00:00:00
abstract：:By means of bioassay-guided separation methods, the cancer cell growth inhibitory constituents residing in the bark, stem and leaves of the Mauritius medicinal plant Terminalia arjuna (Combretaceae) were examined. The cancer cell line active components were found to be gallic acid, ethyl gallate, and the flavone luteo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/S0378-8741(96)01421-3
更新日期：1996-08-01 00:00:00
abstract：:A survey was conducted in southern Punjab, Pakistan, in order to document existing ethnobotanical knowledge by the herdsmen/key respondents about anthelmintics in ruminants. A 3-satge process was used to document the plants being used to treat and/or control helminthes. This paper describes 29 plants to treat helminth...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2006.04.015
更新日期：2006-11-03 00:00:00
abstract：:The alcoholic extract of Trewia polycarpa roots (TPE), which exhibited significant anti-inflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant-induced arthritic rats. The biological defence system constituting the superoxide dismutase, glutathione peroxid...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(03)00143-0
更新日期：2003-09-01 00:00:00
abstract：:An ethanol extract of Acorus calamus rhizomes was screened for CNS effects using a battery of 20 tests in rats and mice. The extract exhibited a large number of actions similar to alpha-asarone (an active principle of A. calamus) but differed from the latter in several other respects including the responses to electro...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(90)90065-2
更新日期：1990-02-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Salvia plebeia R. Brown has been used for the treatment of a variety of inflammatory diseases, cold and tumors in many countries, including Korea and China. AIM OF THE STUDY:This study aimed to assess anti-inflammatory and related activities of an ethanol extract (SPEE) prepared from the...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.08.031
更新日期：2009-11-12 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sarcopoterium spinosum is a Mediterranean plant, widely used by the Beduin traditional medicine. While its major use is for the treatment of diabetes, there are also documentations for its use as anti-inflammatory agent. This therapeutic potential of Sarcopoterium spinosum was not validat...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112391
更新日期：2020-03-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Hyptis fruticosa is a plant native to Brazil with antinociceptive and antiinflamatory properties. This study evaluated the antinociceptive activity of the hydroethanol extract of the plant leaves (CHEE) against orofacial pain as well as its in vitro effect against lipid peroxidation. MAT...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2012.12.031
更新日期：2013-03-07 00:00:00
abstract：:Through data mining a historic herbal text, we identified Atuna racemosa-Raf. as a plant with alleged antibacterial properties. We have shown that these purported antibacterial properties are most prominent in the kernel of the nut of the plant. While working with traditional healers in Samoa during a botanical collec...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.01.020
更新日期：2007-05-22 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cynanchi atrati Radix has been traditionally prescribed for patients with inflammatory fever or chronic tumoral disorders. Melanoma is one of the most devastating cancer types, in which overexpression of nuclear factor kappa B (NF-κB) enables the cancer to survive without apoptosis. To id...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.02.037
更新日期：2014-04-11 00:00:00
abstract：:Semecarpus anacardium nuts are used for variety of disorders in Ayurveda. A chloroform extract of the nut significantly reduced acute carrageenan-induced paw oedema in rats and was active against the secondary lesions of adjuvant-induced arthritis. Delayed hypersensitivity induced in mice by sheep red blood cells as a...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(89)90017-2
更新日期：1989-04-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Vinegar-baked Radix Bupleuri (VBRB) is a processed form of Bupleurum chinense DC. As a well-known meridian-guiding drug, it is traditionally used as a component of traditional Chinese medicine formulations indicated for the treatment of liver diseases. However, the liver targeting compone...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113471
更新日期：2021-03-01 00:00:00
abstract：AIM OF THE STUDY:The aim of this paper is to compare the changes in the utilization of species from various hemeroby categories (indicating the degree of sensitivity of the plant to human impact) using historical data concerning the years 1888-1994. MATERIALS AND METHODS:The authors digitised 8808 handwritten reports,...
journal_title：Journal of ethnopharmacology
pub_type： 历史文章,杂志文章
doi：10.1016/j.jep.2011.02.030
更新日期：2011-05-17 00:00:00
abstract：:The extractives, crude and pure, of Alepidea amatymbica (AA) and Xylopia aethiopica (XA) were subjected to bioassay-directed phytochemical examination for potential cardiovascular and diuretic activity. All extractives and derivatives (XA/O, AA/1, xylopic acid, AA/3, AA/4, AA/5, AA/6, XA/1, XA/2, XA/3) displayed low t...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00285-9
更新日期：2001-10-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Berberine is generally extracted from Rhizoma Coptidis (Coptis chinensis Franch), a traditional Chinese medicine, which can be used in the treatment of intestinal diseases, respiratory infections and cardiovascular diseases. Berberine is especially effective for the treatment of gastroint...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113206
更新日期：2021-01-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The term "traditional" is well established in European (human) medicine and even appears in recent European regulations on herbal medicinal products connected to a simplified registration. In contrast, a scientific discussion of a Traditional European Veterinary Herbal Medicine is still l...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.12.022
更新日期：2019-04-24 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Medicinal plants are widely used for treatment of oral/dental diseases in Uganda. AIM OF THE STUDY:To investigate antibacterial activities of 16 commonly used medicinal plants on microorganisms associated with periodontal diseases (PD) and dental caries (DC). MATERIALS AND METHODS:Pulp ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.06.027
更新日期：2014-08-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:To investigate the synergistic property of Platycodonis radix (PG) in a classic traditional Chinese medicine (TCM) prescription Shengxian decoction (SXT) by combining chemical profile with pharmacokinetic analysis strategy. The synergized prescription consisted of Astragali radix, Anemarr...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.01.033
更新日期：2014-03-28 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Gastrointestinal disorders cause morbidity and can lead to mortality, especially in the developing world where sanitation is deficient. A large part of the human population relies on medicinal plants for treating various diseases, including gastrointestinal disorders. The present review s...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2014.10.014
更新日期：2014-12-02 00:00:00
