A case of myxedema coma presenting as a brain stem infarct in a 74-year-old Korean woman.

Abstract:

:Myxedema coma is the extreme form of untreated hypothyroidism. In reality, few patients present comatose with severe myxedema. We describe a patient with myxedema coma which was initially misdiagnosed as a brain stem infarct. She presented to the hospital with alteration of the mental status, generalized edema, hypothermia, hypoventilation, and hypotension. Initially her brain stem reflexes were absent. After respiratory and circulatory support, her neurologic status was not improved soon. The diagnosis of myxedema coma was often missed or delayed due to various clinical findings and concomitant medical condition and precipitating factors. It is more difficult to diagnose when a patient has no medical history of hypothyroidism. A high index of clinical suspicion can make a timely diagnosis and initiate appropriate treatment. We report this case to alert clinicians considering diagnosis of myxedema coma in patients with severe decompensated metabolic state including mental change.

journal_name

J Korean Med Sci

authors

Ahn JY,Kwon HS,Ahn HC,Sohn YD

doi

10.3346/jkms.2010.25.9.1394

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

1394-7

issue

9

eissn

1011-8934

issn

1598-6357

journal_volume

25

pub_type

杂志文章
  • Varying effects of intravenous immunoglobulin on mononuclear cell proliferation in vitro.

    abstract::Intravenous immunoglobulin (IVIG) is being increasingly used to treat numerous immune-mediated diseases. However, there is a paucity of knowledge on the specific mode of action of IVIG in vivo. In this study, the in vitro effects of IVIG on peripheral blood mononuclear cell (PBMC) proliferation using phytohemagglutini...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.5.544

    authors: Lee KY,Koh DK,Lee JS,Whang KT

    更新日期:2001-10-01 00:00:00

  • 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis.

    abstract:BACKGROUND:Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity has been reported. Therefore, we aimed to investigate if the sufficient serum vit D level is helpful to control disease a...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2020.35.e40

    authors: Kim H,Baek S,Hong SM,Lee J,Jung SM,Lee J,Cho M,Kwok SK,Park SH

    更新日期:2020-02-17 00:00:00

  • Neurologic Manifestations of Enterovirus 71 Infection in Korea.

    abstract::Enterovirus 71 frequently involves the central nervous system and may present with a variety of neurologic manifestations. Here, we aimed to describe the clinical features, magnetic resonance imaging (MRI) findings, and cerebrospinal fluid (CSF) profiles of patients presenting with neurologic complications of enterovi...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2016.31.4.561

    authors: Lee KY,Lee MS,Kim DB

    更新日期:2016-04-01 00:00:00

  • Solid mesenchymal hamartoma of the liver in adult.

    abstract::This paper presents an unusual solid mesenchymal hamartoma of the liver (MHL) in adult. A well defined solid mass in the left lobe of the liver was found in a 57-year-old female. Preoperative radiologic examinations demonstrated solid mass with multifocal calcifications abutting the gallbladder. By light microscopy, t...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.3.335

    authors: Chung JH,Cho KJ,Choi DW,Lee BH,Chi JG

    更新日期:1999-06-01 00:00:00

  • Large subcutaneous calcification in systemic lupus erythematosus: treatment with oral aluminum hydroxide administration followed by surgical excision.

    abstract::A 32-year-old woman with a long-standing systemic lupus erythematosus had multiple subcutaneous nodules on her axillae, iliac crests and limbs. Three years ago, these nodules began to appear and slowly became larger. Some of them amassed to form a large, fungating, lobulated mass on her right iliac crest. Roentgenogra...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.5.589

    authors: Park YM,Lee SJ,Kang H,Cho SH

    更新日期:1999-10-01 00:00:00

  • Impacts of the quinazoline-based alpha1-antagonist, terazosin, and of the sulfonamide derivative, tamsulosin, on serum prostate-specific antigen and prostate volume.

    abstract::The aim of this study was to compare the impacts of terazosin and tamsulosin, on prostate activity, i.e., serum prostate-specific antigen, total prostate volume (TPV), and transition zone volume (TZV). A total of 90 patients who presented with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplas...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2008.23.3.509

    authors: Paick JS,Cho MC,Song SH,Kim SW,Ku JH

    更新日期:2008-06-01 00:00:00

  • A case of torsade de pointes associated with hypopituitarism due to hemorrhagic fever with renal syndrome.

    abstract::We describe a 51-yr-old man presenting with syncope due to torsade de pointes. The torsade de pointes was refractory to conventional medical therapy, including infusion of isoproterenol, MgSO4, potassium, lidocaine, and amiodarone. His past history, physical findings, and hormone study confirmed that QT prolongation w...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.3.355

    authors: Kim NH,Cho JG,Ahn YK,Lee SU,Kim KH,Cho JH,Kim HG,Kim W,Jeong MH,Park JC,Kang JC

    更新日期:2001-06-01 00:00:00

  • Antiviral Efficacy of Tenofovir Monotherapy in Children with Nucleos(t)ide-naive Chronic Hepatitis B.

    abstract:BACKGROUND:The purpose was to compare the efficacy between tenofovir disoproxil fumarate (TDF) and lamivudine (LMV) in children with nucleos(t)ide-naive chronic hepatitis B (CHB) infection. Patients with CHB were treated with TDF in the immune-reactive phase and compared with a historical control group of patients trea...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e11

    authors: Choe JY,Ko JS,Choe BH,Kim JE,Kang B,Lee KJ,Yang HR

    更新日期:2018-01-08 00:00:00

  • Role of healthcare in Korean long-term care insurance.

    abstract::With the rapid aging of the population, Korea introduced public long-term care insurance for older people in 2008. The long-term care insurance was designed as a separate scheme from the national health insurance, with eligibility qualifications and the certification process based on functional disability, benefits an...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2012.27.S.S41

    authors: Kang IO,Park CY,Lee Y

    更新日期:2012-05-01 00:00:00

  • Secretory meningioma--a case report with histopathological, immunohistochemical and ultrastructural analysis.

    abstract::Secretory meningioma have been described as a distinct variant of meningioma based on their histologic, immunohistochemical and ultrastructural features of epithelial and secretory differentiation of meningothelial cells with accumulation of secretory material in the form of hyaline inclusion. Secretory meningioma is ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1996.11.4.369

    authors: Jeong HS,Lee GK

    更新日期:1996-08-01 00:00:00

  • Transcatheter closure of fenestration with detachable coils after the Fontan operation.

    abstract::We report our experience in 13 patients who underwent transcatheter closure of Fontan fenestration with the Cook detachable coils. These patients underwent the extracardiac type Fontan operation with a short conduit fenestration (n=7) or lateral tunnel type with a punch-hole fenestration (n=6). Fenestration closure wa...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2006.21.5.859

    authors: Kim SH,Kang IS,Huh J,Lee HJ,Yang JH,Jun TG

    更新日期:2006-10-01 00:00:00

  • An infrarenal aortic hypoplasia presented with claudication.

    abstract::We describe a case of infrarenal aortic hypoplasia in a 52-yr-old woman who presented with claudication. Computed tomographic angiography revealed an abrupt absence of the infrarenal aorta, with collateral flow reconstituting the iliofemoral systems. After a polytetrafluoroethylene graft was interposed between the aor...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2010.25.6.950

    authors: Sung SA,Hwang YH,Lee SY,Cho YK,Kwon TW

    更新日期:2010-06-01 00:00:00

  • Effect of growth factors on the expression of proto-oncogenes c-fos and c-myc in FRTL-5 cell line.

    abstract::This study was performed to prove the hypothesis that oncogene expressions would have the same patterns with those of cellular growth to growth factors in FRTL-5 cells. Ribonucleic acids of FRTL-5 were extracted at 15', 30', 60' and 120' after administration of growth factors to quiescent FRTL-5, and blotted to the ni...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1995.10.3.155

    authors: Yoo HY,Oh SK,Yi KH,Cho BY,Koh CS

    更新日期:1995-06-01 00:00:00

  • Safety and efficacy of a novel, fenestrated aortic arch stent graft with a preloaded catheter for supraaortic arch vessels: an experimental study in Swine.

    abstract::Thoracic endovascular aortic repair (TEVAR) shows limitations in cases in which the aortic pathology involves the aortic arch. The study aims were to test a fenestrated aortic arch stent graft (FASG) with a preloaded catheter for the supraaortic arch vessels and to perform a preclinical study in swine to evaluate the ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2015.30.4.426

    authors: Kim SP,Lee HC,Park TS,Ahn JH,Lee HW,Park JH,Oh J,Choi JH,Cha KS

    更新日期:2015-04-01 00:00:00

  • Intake of dietary fat and vitamin in relation to breast cancer risk in Korean women: a case-control study.

    abstract::To investigate association between breast cancer risk and nutrients intake in Korean women, a case-control study was carried out, at Seoul, Korea. Incident cases (n=224) were identified through the cancer biopsy between February 1999 and December 2000 at two University hospitals in Seoul. Hospital-based controls (n=25...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.4.534

    authors: Do MH,Lee SS,Jung PJ,Lee MH

    更新日期:2003-08-01 00:00:00

  • Seasonal Variations and Associated Factors of Gout Attacks: a Prospective Multicenter Study in Korea.

    abstract:BACKGROUND:We purposed to evaluate the seasonality and associated factors of the incidence of gout attacks in Korea. METHODS:We prospectively enrolled patients with gout attacks who were treated at nine rheumatology clinics between January 2015 and July 2018 and followed them for 1-year. Demographic data, clinical and...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,多中心研究

    doi:10.3346/jkms.2020.35.e133

    authors: Choi HJ,Moon KW,Kim HO,Lee YA,Hong SJ,Jung JY,Kim HA,Suh CH,Ha YJ,Kim IJ,Lee J,Park EK,Lee SG,Seo MR,Baek HJ,Choi ST,Song JS

    更新日期:2020-05-25 00:00:00

  • The tumor necrosis factor beta * 1 allele is linked significantly to HLA-DR8 in Koreans with atrophic autoimmune thyroiditis who are positive for thyrotropin receptor blocking antibody.

    abstract::The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a TNF beta gene polymorphism is associated with autoimmune thyroiditis, we analyzed the TNF beta gene polymo...

    journal_title:Journal of Korean medical science

    pub_type: 临床试验,杂志文章

    doi:10.3346/jkms.1994.9.2.155

    authors: Chung JH,Cho BY,Lee HK,Kim TG,Han H,Koh CS

    更新日期:1994-04-01 00:00:00

  • Expression of cyclin dependent kinase inhibitor p21WAF1 alone and in combination with p27KIP1 shows prognostic value in gastric carcinoma.

    abstract::Evidence suggests that multiple molecular events, including alteration of cell cycle regulators are involved in the development and progression of gastric carcinoma. Recently, it has been reported that the expression of p21 and p27, integrating the effects of one or more cell cycle regulators, consequently, acting as ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1998.13.4.369

    authors: Jang SJ,Ahn MJ,Paik SS,Kong G,Keum JS,Park YW,Lee JD

    更新日期:1998-08-01 00:00:00

  • Giant cystic chondroid hamartoma.

    abstract::We report a case of huge pulmonary chondroid hamartoma with multilocular cysts in a 38-yr-old male patient. The lobectomy specimen of the left lower lobe showed a large multilocular cystic mass, 11.5 x 10 cm in size. The mass had thin-walled, variable-sized cysts and areas of solid cartilaginous small nodules in the i...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.3.509

    authors: Kim GY,Han J,Kim DH,Kim J,Lee KS

    更新日期:2005-06-01 00:00:00

  • Changes of Epidemiological Characteristics of Japanese Encephalitis Viral Infection and Birds as a Potential Viral Transmitter in Korea.

    abstract::Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity. Pigs are known as amplifying host of JE virus (JEV), but do not play an important role in these recent events because pig-breeding is not common in Seoul. The distribution and the density of migratory birds ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e70

    authors: Bae W,Kim JH,Kim J,Lee J,Hwang ES

    更新日期:2018-02-26 00:00:00

  • Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. II. Kinetic properties of AP DNA endonucleases in rat liver chromatin.

    abstract::An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about optimal activities of AP DNA endonucleases and N-ethylmaleimide or HgCl2 in...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1990.5.3.137

    authors: Kim YS,Kim JW,Lee SE,Oh SH

    更新日期:1990-09-01 00:00:00

  • Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More.

    abstract:BACKGROUND:The purpose of this study was to evaluate whether institutional case volume affects clinical outcomes in patients receiving mechanical ventilation for 48 hours or more. METHODS:We conducted a nationwide retrospective cohort study using the database of Korean National Healthcare Insurance Service. Between Ja...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2019.34.e212

    authors: Lee H,Choi S,Jang EJ,Lee J,Kim D,Yoo S,Oh SY,Ryu HG

    更新日期:2019-09-02 00:00:00

  • Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists.

    abstract::Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders. A range of NMS, particularly hyposmia, sleep disturbances...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.2020.35.e230

    authors: Choi JH,Kim JM,Yang HK,Lee HJ,Shin CM,Jeong SJ,Kim WS,Han JW,Yoon IY,Song YS,Bae YJ

    更新日期:2020-07-20 00:00:00

  • Serum level of interleukin-33 and soluble ST2 and their association with disease activity in patients with Behcet's disease.

    abstract::Interleukin (IL)-33 is an important mediator of innate immunity. Behcet's disease (BD) is an autoinflammatory disorder characterized by hyperactivity of the innate immune response. We measured serum levels of IL-33 and its receptor soluble ST2 (sST2) in patients with BD to investigate their association with disease ac...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2013.28.8.1145

    authors: Kim DJ,Baek SY,Park MK,Park KS,Lee JH,Park SH,Kim HY,Kwok SK

    更新日期:2013-08-01 00:00:00

  • Erysipelothrix rhusiopathiae peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis.

    abstract::Erysipelothrix rhusiopathiae is known as a pathogen of occupational diseases or a zoonosis. We report a case of E. rhusiopathiae peritonitis in a 50-yr-old male undergoing continuous ambulatory peritoneal dialysis (CAPD). He was suffered from mild abdominal pain with a distinctive erysipeloid skin lesion. E. rhusiopat...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2010.25.8.1234

    authors: Shin SJ,Gwak WG

    更新日期:2010-08-01 00:00:00

  • Polypoid endobronchial lung cyst with bronchoscopic removal: a case report.

    abstract::Pulmonary bronchogenic cyst in adults is rare and the typical appearance is a sharply circumscribed, round or oval nodule or mass, usually in the medial third of the lungs. Bronchial polyps are rare histopathologically distinct nonneoplastic endobronchial lesions and are classified as multiple papillomas, solitary pap...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.5.892

    authors: Kim JH,Jang AS,Park JS,Lee JH,Park SW,Koh ES,Park JS,Park CS

    更新日期:2005-10-01 00:00:00

  • Reliability and validity of the Korean version of the internet addiction test among college students.

    abstract::We developed a Korean translation of the Internet Addiction Test (KIAT), widely used self-report for internet addiction and tested its reliability and validity in a sample of college students. Two hundred seventy-nine college students at a national university completed the KIAT. Internal consistency and two week test-...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2013.28.5.763

    authors: Lee K,Lee HK,Gyeong H,Yu B,Song YM,Kim D

    更新日期:2013-05-01 00:00:00

  • Pediatric Deaths Attributed to Complex Chronic Conditions over 10 Years in Korea: Evidence for the Need to Provide Pediatric Palliative Care.

    abstract:BACKGROUND:Pediatric palliative care (PPC) is the active total care of children suffering from life-threatening illnesses. Palliative care includes symptom management, psychosocial support, and end-of-life care. Despite significant advances in disease diagnosis and treatment, resources for PPC of children with serious ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e1

    authors: Kim MS,Lim NG,Kim HJ,Kim C,Lee JY

    更新日期:2018-01-01 00:00:00

  • Identification of Downstream Genes of the mTOR Pathway that Predict Recurrence and Progression in Non-Muscle Invasive High-Grade Urothelial Carcinoma of the Bladder.

    abstract::Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the bladder, gene expression patterns, gene ontology, and gene clustering by triple (p70S6K, S6K, a...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2017.32.8.1327

    authors: Jin S,Chang IH,Kim JW,Whang YM,Kim HJ,Hong SA,Lee TJ

    更新日期:2017-08-01 00:00:00

  • TAP1 and TAP2 gene polymorphisms in Korean patients with allergic rhinitis.

    abstract::Antigen peptides are actively transported across the endoplasmic reticulum by the transporters associated with antigen presentation (TAP). TAP genes polymorphism could influence the selection process that determines which antigen peptides play a role in the pathogenesis of allergic rhinitis. The aim of this study was ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2007.22.5.825

    authors: Kim KR,Cho SH,Choi SJ,Jeong JH,Lee SH,Park CW,Tae K

    更新日期:2007-10-01 00:00:00