Detection of Hodgkin lymphoma within ovarian tissue.

Abstract:

OBJECTIVE:To describe the detection of Hodgkin lymphoma within ovarian tissue taken at the time of harvest for cryopreservation. DESIGN:Case report. SETTING:University-affiliated women's hospital. PATIENT(S):A 19-year-old woman diagnosed with Hodgkin lymphoma. INTERVENTION(S):Laparoscopic removal of ovarian tissue for cryopreservation. MAIN OUTCOME MEASURE(S):Histologic and immunohistochemical evaluation of ovarian tissue harvested for fertility preservation. RESULT(S):Histologic and immunohistochemical identification of Hodgkin lymphoma within ovarian tissue harvested for cryopreservation. CONCLUSION(S):Ovarian cryopreservation and subsequent autografting is a procedure still in an experimental phase that has yielded promising findings. This option is frequently offered to young women with neoplasms such as Hodgkin lymphoma. Although the risk of Hodgkin lymphoma infiltration into the ovary may be low, the identification of lymphoma in this case emphasizes the importance of histologic examination of ovarian tissue before freezing and indicates that there is a possibility of reintroducing tumor.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Bittinger SE,Nazaretian SP,Gook DA,Parmar C,Harrup RA,Stern CJ

doi

10.1016/j.fertnstert.2010.07.1068

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

803.e3-6

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)02181-3

journal_volume

95

pub_type

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