Abstract：
:Whole body vibration (WBV) is a novel modality that has been demonstrated to enhance muscular and cardiovascular functions reported to increase fibrinolytic activity. The purpose of this study was to examine the fibrinolytic response to WBV and exercise in men. Twenty healthy males (23.8 ± 0.9 years, 25.6 ± 0.2 kg m(-2)) participated in the study. Each subject performed three trials in randomized order separated by 1 week: exercise (X), vibration (V) and vibration + exercise (VX). Exercise sessions consisted of 15 min of unloaded squatting at a rate of 20 per minute. Vibration sessions were conducted on a WBV platform vibrating for 15 min. Tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI-1) were assessed at baseline and immediately after each condition. The increase in tPA activity was significantly greater in VX (0.87 ± 0.35 to 3.21 ± 1.06 IU ml(-1)) compared to X (0.71 ± 0.36 to 2.4 ± 1.13 IU ml(-1)) or V (0.83 ± 0.25 to 1.00 ± 0.37 IU ml(-1)) conditions, and greater in the X condition compared to the V condition. PAI-1 activity decreased significantly more in the VX (6.54 ± 5.53 to 4.89 ± 4.13 IU ml(-1)) and X (9.76 ± 8.19 to 7.48 ± 7.11 IU ml(-1)) conditions compared to the V (5.68 ± 3.53 to 5.84 ± 3.52 IU ml(-1)) condition. WBV does not augment fibrinolytic activity in healthy men. However, WBV combined with squatting exercise increases fibrinolytic activity more than exercise alone.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Boyle LJ,Nagelkirk PRdoi
10.1007/s00421-010-1590-8subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1057-61issue
5eissn
1439-6319issn
1439-6327journal_volume
110pub_type
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