Abstract:
OBJECTIVE:To determine optimal management with one or two mature follicles after stimulation. DESIGN:Retrospective analysis. SETTING:Lister fertility clinic. PATIENT(S):A total of 1,350 IVF/intracytoplasmic sperm injection cycles (7.3% of total) during 1998-2009 were found to have one or two mature follicles. INTERVENTION(S):Group 1 (n = 807) comprised those who proceeded to vaginal egg collection (VEC) (59.8%; outcome per egg collection), group 2 (n=248) those who converted to IUI (18.4%; outcome per insemination) and group 3 (n=259) those who abandoned the current cycle (21.9%; outcome per abandoned cycle in first subsequent cycle). MAIN OUTCOME MEASURE(S):Live birth rate, clinical pregnancy rate, and biochemical pregnancy rate. RESULT(S):Biochemical pregnancy rates of 13.1%, 4.9%, and 9.7%, clinical pregnancy rates of 8.1%, 3.6%, and 7.2%, and ongoing pregnancy rates of 6.8%, 2.0%, and 5.5% were achieved in groups 1, 2, and 3, respectively. All pregnancy outcomes were significantly higher after VEC (group 1) than for those converted to IUI (group 2), and all pregnancy outcomes were higher with borderline significance in group 3 vs. group 2. There was no significant difference in outcome between groups 1 and 3. CONCLUSION(S):Our data suggest that for such poor responders, proceeding to VEC may represent their best chance of successful outcome. Conversion to IUI offers the poorest outcome, and despite the potential for improvements in cycle protocol, abandoning and a further attempt does not improve outcome (using abandoned cycle as the denominator).
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Nicopoullos JD,Abdalla Hdoi
10.1016/j.fertnstert.2010.05.030subject
Has Abstractpub_date
2011-01-01 00:00:00pages
68-71issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(10)00820-4journal_volume
95pub_type
杂志文章abstract::The serial measurement of serum hCG concentrations is an important clinical tool used to differentiate normal from abnormal pregnancies. At hCG values below which ultrasonography can be diagnostic, the comparison of a patient's hCG dynamics to those of established expected curves of rise or fall can aid the clinician ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2012.09.014
更新日期:2012-11-01 00:00:00
abstract::In a qualitative interview study of 77 families with stored frozen embryos, we found that while embryo disposition decision making was influenced by individual life circumstances, embryo quantity/quality, personal values, embryo conceptualization, and clinic information, it was a stepwise process that could be represe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.06.027
更新日期:2009-12-01 00:00:00
abstract::Reportedly, gamete intrafallopian transfer and zygote intrafallopian transfer are successful methods in assisted conception. This pilot study describes the experiences and results of a recently developed technique of vaginal transcervical intrafallopian transfer. In a group of 38 women with unexplained infertility, oo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53704-2
更新日期:1990-08-01 00:00:00
abstract::The incidence of transient hyperprolactinemia and its impact on in vitro fertilization (IVF) were determined in 151 euprolactinemic women with tubal infertility undergoing an identical gonadotropin stimulation for IVF. Prolactin (PRL) levels were measured on the morning of cycle day 3, days of human chorionic gonadotr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60975-5
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that adrenal androgen (AA) secretion is an inherited trait in PCOS and that serum DHEAS concentrations, as a marker of AA secretion, will be correlated between women with PCOS and their sisters. DESIGN:Prospective case-control. SETTING:Tertiary care center. PATIENT(S):Sixty-two PCOS ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.05.045
更新日期:2006-12-01 00:00:00
abstract::A specially designed rigid salpingoscope has been developed to allow inspection of the tubal mucosa during laparoscopy. The presence and extent of intratubal adhesion formation can be evaluated more accurately by this technique than by either HSG or laparoscopy. In 22 patients with bilateral hydrosalpinges, an intraut...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60501-0
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of L-carnitine (LC) or L-acetyl-carnitine (LAC) or combined LC and LAC treatment in improving semen kinetic parameters and the total oxyradical scavenging capacity in semen. DESIGN:Placebo-controlled, double-blind, randomized trial. SETTING:Andrology unit, Department of Interna...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2005.03.064
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To assess whether trophectoderm biopsy has any impact on the level of serum β-human chorionic gonadotropin (β-hCG) in early pregnancies. DESIGN:Retrospective cohort study. SETTING:University-affiliated reproductive medical center. PATIENT(S):Three hundred and eighty-three women undergoing 396 frozen embryo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.05.015
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:To evaluate whether circulating levels of antimüllerian hormone (AMH) predict fecundability in young healthy women. DESIGN:Prospective cohort study. SETTING:General community. PATIENT(S):A total of 186 couples who intended to discontinue contraception to become pregnant were followed until pregnancy or for...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.08.008
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To present two cases of ectopic twin pregnancy in a Cesarean section scar following IVF-embryo transfer. DESIGN:Case report. SETTING:Tertiary referral case center. PATIENT(S):Two women who had ectopic twin pregnancy in a Cesarean section scar, in both cases following IVF and embryo transfer. INTERVENTION(...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.11.091
更新日期:2008-11-01 00:00:00
abstract::This study was initiated to determine whether factors are present in human sperm-free seminal plasma (HSP) that regulate the uptake and release of carnitine from sperm. Bovine caput epididymal sperm cells accumulated more carnitine than caudal sperm cells. A significant reduction in carnitine uptake by caput sperm was...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00
abstract::The comprehensive "one-stop shop" ultrasound evaluation of an infertile woman, performed around cycle days 5 to 9, will reveal abundant information about the anatomy and morphology of the pelvic organs and thereby avoid costly radiation and iodinated contrast exposure. We propose a two-dimensional and three-dimensiona...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2016.03.026
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To assess the potential involvement of vascular endothelial growth factor in the hyperpermeability characterizing the ovarian hyperstimulation syndrome (OHSS). DESIGN:A controlled clinical study that followed the kinetics of vascular endothelial growth factor in the plasma of patients with severe OHSS from t...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/S0015-0282(97)81908-5
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To establish the prevalence of endometriosis metastatic to pelvic sentinel lymph nodes (PSLN) in women with ovarian and/or peritoneal endometriosis. DESIGN:Prospective clinical study. SETTING:Academic research institution. PATIENT(S):Women with a laparoscopic diagnosis of ovarian and/or peritoneal endometr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.06.070
更新日期:2011-09-01 00:00:00
abstract::Four individuals with a complaint of infertility were evaluated after a semen analysis had demonstrated no motility. The semen analyses were otherwise normal, with the exception of a low count in one subject. All had normal percentages of living sperm. One of the individuals had chronic respiratory disease, and two ot...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47549-7
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To determine the prognostic impact of the nuclear status at the two-cell stage on intracytoplasmic sperm injection (ICSI) outcomes. DESIGN:Retrospective study. SETTING:Hospital. PATIENT(S):Only ICSI cycles with time-lapse monitoring of transferred embryos with known implantation/delivery data from November...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.09.022
更新日期:2017-01-01 00:00:00
abstract::The initial experience with the use of a portable infusion pump for the delivery of human menopausal gonadotropins (hMG) in the therapy of ovulation dysfunction of women who failed to conceive following (1) either clomiphene citrate (five patients with polycystic ovary syndrome) or danazol (three patients with mild en...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47352-8
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:To describe trends in age-specific incidence rates of female sterilization (FS) procedures in Western Australia and to evaluate the effects of the introduction of government-subsidized contraceptive methods and the implementation of the Australian government's baby bonus policy on FS rates. DESIGN:Population...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.04.035
更新日期:2016-09-01 00:00:00
abstract::Paternal aging is associated with increased risk of genetic disease transmission to the offspring. The changes associated with aging arise predominantly through formation of single nucleotide variation through DNA replication errors, as well as possibly chronic exposure to environmental toxins and reactive oxygen spec...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2016.12.021
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that danazol increases the impedance to uterine circulation and hence reduces the effective uterine blood flow after a predetermined period of therapy. DESIGN:Prospective, longitudinal study. SETTING:Reproductive medicine unit of a university teaching hospital. PATIENT(S):Eight preme...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00161-2
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVES:To study the effect of GnRH agonist (GnRH-a) treatment on memory and to assess the role of psychological factors. DESIGN:A randomized prospective study. SETTING:An academic teaching hospital. PARTICIPANTS:Women with endometriosis and infertility or endometriosis alone. MAIN OUTCOME MEASURES:Memory Observ...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)58351-4
更新日期:1996-06-01 00:00:00
abstract::The Ericsson albumin filtration technique was used to collect a fraction rich in Y sperm for selective insemination in couples desiring a male infant. Of 35 conceptions in which sex was known at delivery or spontaneous abortion, there were 28 males (80%). Twelve pregnancies were achieved after separation of sperm in a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of the second micro-testicular sperm extraction (TESE)in men with nonobstructive azoospermia in whom the first micro-TESE failed. DESIGN:Retrospective. SETTING:Private clinic. PATIENT(S):One hundred twenty-five men with nonobstructive azoospermia with failed previous micro-TESE. Th...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.10.005
更新日期:2020-12-23 00:00:00
abstract:OBJECTIVE:To define a therapeutic strategy adapted to acute urine retention resulting from uterine incarceration in early pregnancy. DESIGN:Case report and review of the literature. SETTING:University hospital. PATIENT(S):Two cases of acute urine retention induced by severe fibroid incarceration in first trimester. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2007.10.008
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To report an update on the role of vitamin D (VD) in ovarian physiology with a focus on genes involved in steroidogenesis, follicular development, and ovarian reserve, as well as ovulatory dysfunction associated with polycystic ovary syndrome (PCOS), and ovarian response to assisted reproductive technology (A...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2014.04.046
更新日期:2014-08-01 00:00:00
abstract::This article provides a summary of the biopsychosocial model and the assessment and treatment of male sexual dysfunction as manifested in cases of infertility. In couples trying to get pregnant, a unique set of psychosocial and behavioral changes may evolve that directly interferes with a couple's usual pattern of sex...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2015.07.1155
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To explore the value of serum vascular endothelial growth factor (VEGF) concentrations during IVF cycles in predicting the risk of ovarian hyperstimulation syndrome (OHSS). DESIGN:Prospective study. SETTING:London Women's Clinic. PATIENT(S):One hundred seven women undergoing IVF. Mild OHSS developed in 10 ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(98)00447-6
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVES:To evaluate sequential changes in fetal heart rate (FHR) during the first trimester of well-timed pregnancies resulting from infertility treatment and to correlate the data with fetal growth curve and beta-hCG levels. DESIGN:Serial measurements of FHR, crown-rump length (CRL) and beta-hCG at weekly interval...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)55971-8
更新日期:1993-06-01 00:00:00
abstract:OBJECTIVE:To evaluate whether adolescent obesity is associated with difficulties in becoming pregnant later in life. DESIGN:Cross-sectional analysis of baseline data from a longitudinal cohort. SETTING:Multiethnic, community-based observational study of U.S. women. PATIENT(S):Three thousand one hundred fifty-four mi...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2008.12.059
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the pregnancy and delivery outcome of robot-assisted tubal reanastomosis. DESIGN:Retrospective cohort study. SETTING:University hospital. PATIENT(S):Ninety-seven patients with available follow-up who underwent the reversal of tubal ligation, with a median age of 37 years (range, 24-47 years). ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.10.028
更新日期:2010-10-01 00:00:00