Abstract：
OBJECTIVES:Effective delivery of active agents to dental hard tissues is critical to product performance and pertinent to biofilm control, caries, erosion, hypersensitivity and tooth bleaching. The aim of this study was to investigate in vitro the bioadhesion and retention behaviour of non-aqueous delivery systems (NADS) based on glycerol, PEG 400, Carbopol 974P and triclosan. METHODS:Tensile testing was employed to calculate the work of adhesion (WOA) and maximum force of detachment (F(max)) for formulations applied to hydroxyapatite (HA) and pellicle-coated HA surfaces (HAP). Formulation substantivity under conditions of dynamic flow was studied by monitoring the release of incorporated triclosan. The release data were fitted to a first-order model to generate a removal half-life (t(1/2)). RESULTS:Tensile testing showed a clear positive relationship between Carbopol concentration and bioadhesion. Increasing the PEG 400 concentration in formulations containing glycerol, 2% (w/w) Carbopol and 0.30% triclosan produced a local minimum for both WOA and F(max) at 10% (w/w). Values for WOA and F(max) decreased threefold in the presence of a salivary pellicle. Good correlations were obtained between (i) WOA and F(max) and (ii) WOA and t(1/2) and (iii) the elastic modulus of the formulations and t(1/2). CONCLUSION:The presence of a salivary pellicle markedly reduced the bioadhesive interaction between the NADS and the substrate. Increased Carbopol content appeared to be the dominant factor in promoting the WOA, elasticity and retention of NADS to HA surfaces. Such formulations might provide a suitable platform for developing systems suitable for promoting retention to hard surfaces within the oral cavity.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Zaman MA,Martin GP,Rees GDdoi
10.1016/j.jdent.2010.06.005subject
Has Abstractpub_date
2010-09-01 00:00:00pages
757-64issue
9eissn
0300-5712issn
1879-176Xpii
S0300-5712(10)00153-3journal_volume
38pub_type
杂志文章abstract：OBJECTIVE:This randomized controlled trial compared the survival of glass fibre and cast metal dental posts used to restore endodontically treated teeth with no remaining coronal wall. METHODS:Fifty-four participants (45 women) and 72 teeth were evaluated during a follow-up period of up to 3 years. Teeth were randomly...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2014.02.003
更新日期：2014-05-01 00:00:00
abstract：:Enamel blocks bearing artificial caries are used in intra-oral appliances for cariogenicity tests. These blocks are often sterilised to prevent the possibility of cross-infection via this route. This study therefore aimed to determine the effect of sterilisation methods on the structural integrity of artificial enamel...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(98)00064-5
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVES:To compare the accuracies of 4 laboratory scanners using a new custom-made block for complete-arch implant rehabilitation. MATERIALS AND METHODS:A block comprised 4 cylinders, with 2 in the anterior (0° angulation) and 2 in the posterior region (45° distal angulation) (Experimental group) and a standard blo...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2020.103476
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate the influence of different titanium zirconium (TiZr) alloy surfaces on primary human gingival fibroblasts (HGF) for improved soft tissue integration of dental implants. METHODS:TiZr polished, machined and machined+HCl/H2SO4 acid-etched surfaces were modified by cathodic...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2013.11.003
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:This study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ. METHODS:Volunteers (n=10) wore palatal devices holding four bovine enamel blocks. The treatments involved 5 experimental phases of 3 days each according to the followi...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2014.09.001
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:The fracture of bonded ceramic to metal restorations remains a problem in clinical dental practice. The use of resin based composites to repair such fractures is generally unsatisfactory. Tribochemical technology creates a surface layer of small silica particles fused to the surface substrate. Such a layer po...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(00)00006-3
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVE:To investigate whether bleaching prior to placement of a composite veneer had an effect on the final shade of the restoration and whether this was affected by the thickness or shade of the veneer. METHODS:Twenty bovine teeth were collected, sectioned and divided into two groups. One group was the non-bleache...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.04.004
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:The demand for restoration of root dentine defects such as cervical erosion and root caries has significantly increased recently, but there is limited information on the performance of the adhesive resins to radicular dentine. The purpose of this study was to measure the regional tensile bond strength (TBS) ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(95)00102-6
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVE:This study compared the effect of water sorption on the extent of marginal gap reduction in a compomer (Dyract AP, Dentsply) and a composite (Spectrum, Dentsply) over a 12-week storage period. MATERIALS AND METHODS:Artificial gaps were created in 40 borosilicate glass cylinders, each 5mm deep and with an int...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(01)00053-7
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the influence of different surface treatments on the microtensile bond strength of a dual-cured resin composite to fiber posts. METHODS:Thirty-two glass methacrylate-based fiber posts (GC Corp.) were used in the study. Posts were divided into two groups, according to the surface pretreatment per...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2007.01.009
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVE:The shear bond strengths of an autopolymerizing denture base resin to cast Ti-6Al-7Nb and Co-Cr alloys using three metal conditioners were investigated. METHODS:Ti-6Al-7Nb alloy and Co-Cr alloy discs were cast. The disc surfaces were air-abraded with 50 microm alumina particles and treated with three metal c...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.05.002
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVES:The main objective is the characterisation of the setting reaction in glass ionomer cements based on experimental ionomer glasses with different fluorine content and a commercial glass ionomer cement liquid by using 13C CP/MAS-NMR, 29Si, 27Al and 31P MAS-NMR spectroscopy in order to receive information speci...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.08.006
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVES:In some studies gap formation has been evaluated in just one section of the restorative. This in vitro study aimed to design a quantitative three-dimensional method for evaluation of the contraction gap in restoratives. METHODS:Cervical cavities were prepared on buccal, palatal or lingual surfaces in human ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2004.10.001
更新日期：2005-04-01 00:00:00
abstract：:In a previous study concerning oral function with shortened dental arches, it was found that approximately 10 per cent of the patients investigated complained of impaired masticatory ability despite a substantial reduction in arch length and, as a consequence, food platform area. This finding differs from those of stu...
journal_title：Journal of dentistry
pub_type： 杂志文章,评审
doi：10.1016/0300-5712(90)90107-p
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVES:Tooth shade is crucial to patient satisfaction in aesthetic dentistry. Two-dimensional (2D) clinical photographs have been widely used to record patients' tooth shade for creation of beautiful smile. However, in the digital workflow, 3D virtual teeth models in open file format contain only mesh information w...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.09.009
更新日期：2018-12-01 00:00:00
abstract：AIM:The aim of this study is to report the subsequent treatment provided, over the 11 years' data available, when a re-intervention was considered clinically necessary on a glass ionomer (GI) restoration. METHODS:A detailed sample of treatment records of patients has been established at the Dental Practice Division of...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.07.008
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:To investigate, in a sample of probable sleep bruxers with and without temporomandibular disorder (TMD) pain, the presence and relationships between clinical jaw-muscle symptoms, and test their associations with jaw-muscle electromyographic (EMG) activity during sleep. METHODS:Pain, unpleasantness, tirednes...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2019.05.016
更新日期：2019-06-01 00:00:00
abstract：:Ultrasound in the kHz frequency range is used widely in clinical dentistry. The most common uses are in the fields of periodontology and endodontics. The ultrasonic scaler works by the vibratory chipping action of the oscillating tip and is assisted by the presence of cavitational activity in the associated cooling wa...
journal_title：Journal of dentistry
pub_type： 杂志文章,评审
doi：10.1016/0300-5712(92)90003-u
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to evaluate the intra- and inter-examiner variability of a panel of examiners using a 'glance and grade' marking system when assessing Class II preparations. METHODS:The examination panel consisted of five university staff with varying clinical and teaching experience. The panel...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(97)00033-x
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVES:All-ceramic crowns have become increasingly used also in the posterior regions, but there are only few studies documenting the clinical outcome of these restorations. The aim was therefore to present the 3-year outcome of zirconia (NobelProcera) single crowns. METHODS:All patients treated with porcelain-ven...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2009.06.002
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:Evaluate the dentine bond strength using different methods of application of opaque resins to mask dentine discoloration. MATERIALS AND METHODS:Dentine was exposed on 21 extracted molars which were assigned to 3 groups: G1: immediate dentine sealing (IDS). G2: IDS+opaque. G3: IDS with adhesive resin mixed with...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2011.07.005
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVES:Systemic conditions may affect host susceptibility, disease progression and severity as well as treatment response. Previously, low oestrogen (E(2)) levels were associated with increased bone resorption, due to increased osteoclastogenesis and decreased osteoclast apoptosis. Osteoprotegerin (OPG) is an essen...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.01.013
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:To compare a silver-reinforced glass ionomer material (cermet) with a resin-modified glass ionomer in minimal Class II preparations in primary teeth. METHODS:Matched pairs of primary molars with approximal caries that required operative treatment were used. Each cavity was filled with either Vitremer or Keta...
journal_title：Journal of dentistry
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0300-5712(99)00004-4
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVE:This study aims to analyze the addition of niobium silicate particles to dental adhesive resins and evaluate its physicomechanical and biological properties. METHODS:The SiNb particles were produced by the sol-gel route and presented a mean particle size of 2.1 μm and a specific surface area of 616,96m2/g. A...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2020.103449
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVES:The tooth-resin bond is the weak link of restoration, with secondary caries as a main reason for failure. Calcium phosphate-containing resins are promising for remineralization; however, calcium (Ca) and phosphate (P) ion releases last only a couple of months. The objectives of this study were to develop the...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2015.06.009
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:To examine the effect of incorporating arginine in a 5% sodium fluoride (NaF) varnish on its remineralization potential and HGF-1 cytotoxicity. METHODS:Experimental varnishes were prepared using two arginine variants: l-arginine (Arg) and l-arginine monohydrochloride (Arg.HCl) at 2%, 4%, & 8% w/v. with cont...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2020.103411
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to compare the fracture strength of three techniques used to re-attach tooth fragments in sound and endodontically treated fractured teeth with or without fiber post placement. MATERIAL AND METHODS:Ninety human lower incisors were randomly divided into three groups of 30 teeth each...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.01.001
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to investigate the correlation between fit accuracy and fracture resistance of zirconia abutments, as well as its feasibility for clinical applications. METHODS:Twenty self-made zirconia abutments were tested with 30 Osstem GSII implants. First, 10 Osstem GSII implants were cut ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2014.02.008
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the kinetics of protein interactions with a novel hydroxyapatite-polylactide (HA-PLA) composite membrane material. METHODS:Trilayer PLA and HA-PLA composite membranes reinforced with PLA fibres were used to absorb and release protein which was measured by a BioRad as...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2009.06.014
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVES:A meta-analysis was conducted to assess the relationship between parental age and the occurrence of non-syndromic oral clefts. The questions addressed if younger or older mothers and fathers have an increased risk of having a child with non-syndromic oral clefts. DATA:Data from cohort studies, case-control,...
journal_title：Journal of dentistry
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jdent.2011.10.002
更新日期：2012-01-01 00:00:00
