Abstract：
OBJECTIVES:The aim of this study was to investigate the kinetics of protein interactions with a novel hydroxyapatite-polylactide (HA-PLA) composite membrane material. METHODS:Trilayer PLA and HA-PLA composite membranes reinforced with PLA fibres were used to absorb and release protein which was measured by a BioRad assay. The proteins used were fetal calf serum and bovine serum albumin. PLA and HA-PLA composite films were manufactured to test permeability. RESULTS:Maximal protein absorption was seen within 5min of treating materials; a nearly 8-fold increase in total absorption was seen with HA-containing composites compared to those without HA. These also exhibited a more gradual and sustained release of protein for periods of up to 96h, for example at 24h protein concentrations released were 2.20+/-2.80 and 0.49+/-5.38microg/ml for membranes with and without HA respectively. In addition low pressure and temperature used during production of membranes also allowed greater and more sustained protein release. HA-PLA composite films also showed marked increased permeability compared to plain PLA films, for example after 24h PLA only films 3.64+/-1.01microg/ml, PLA film with 25% HA: 44.99+/-35.61microg/ml, PLA film with 75% HA: 153.12+/-65.57microg/ml. CONCLUSIONS:The results demonstrate that these composite membranes rapidly absorb protein and that the absorbed protein is released slowly for periods of up to 96h, dependent on constituents of the material and the manufacturing conditions. Incorporation of HA into these membranes was the key factor for improved protein kinetics and membrane permeability.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Talal A,Waheed N,Al-Masri M,McKay IJ,Tanner KE,Hughes FJdoi
10.1016/j.jdent.2009.06.014subject
Has Abstractpub_date
2009-11-01 00:00:00pages
820-6issue
11eissn
0300-5712issn
1879-176Xpii
S0300-5712(09)00158-4journal_volume
37pub_type
杂志文章abstract：OBJECTIVES:The study evaluated the antibacterial effect of VIOlight (VL) Personal Travel Toothbrush Sanitizer on biofilms after toothbrush exposure to human saliva compared to Listerine Antiseptic (LA), 3% hydrogen peroxide (3%HP) and water. METHODS:Twenty toothbrush heads (n=5/Gp) were immersed in saliva and to allow...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2009.08.011
更新日期：2010-08-01 00:00:00
abstract：:A significant correlation was found between the number of mutans streptococci in saliva and the proportional distribution of these microorganisms in pooled plaque from the margins of all restorations. At high salivary numbers there was a tendency towards a higher porportion of mutans streptococci in plaque from the ma...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(92)90130-5
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVES:To determine the correlation between fracture toughness and leucite content in dental porcelains. The mechanisms by which leucite influences the fracture toughness of dental porcelains were also investigated. METHODS:Six porcelains were tested: A (Ceramco I/Dentsply), B (Ceramco II/Dentsitply), C (Finesse/D...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.02.001
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:Silver compounds have been used for their medical properties for centuries and in dentistry for more than a century. The aim of this review is to examine the evidence supporting the therapeutic use of silver in dentistry and the outcomes from the clinical trials, as well as mode of action and biocompatibility...
journal_title：Journal of dentistry
pub_type： 杂志文章,评审
doi：10.1016/j.jdent.2012.03.009
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVES:The dysbiotic oral microbiome plays a key role in the pathogenesis of caries in children. Topical application of casein phosphopeptide-amorphous calcium phosphate containing fluoride (CPP-ACP/F) is an effective treatment modality for children with caries (CC). Hitherto the mechanism by which CPP-ACP/F module...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2021.103582
更新日期：2021-01-12 00:00:00
abstract：:OBJECTIVES.: To compare the safety and plaque removal efficacy of two oscillating/rotating/pulsating toothbrushes (Oral-B ProfessionalCaretrade mark 7000 [PC 7000] and Oral-B 3D Excel [3DE]) and a high-frequency toothbrush (Sonicare(R) Advance, Philips Oral Healthcare; SA) in a single-use, examiner-blind, three period...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVES:Manufacturers are adding fluoride (F) to calcium-containing chewing gums to further promote enamel remineralization. The aim of this study was to assess the effect of a chewing gum containing phosphoryl oligosaccharides of calcium (POs-Ca) and fluoride on remineralization of enamel subsurface lesions, in a d...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2011.08.009
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to investigate: (1) the antibacterial activity of two antibacterial monomers, dimethylaminododecyl methacrylate (DMADDM) and dimethylammoniumethyl dimethacrylate (DMAEDM), against eight different species of oral pathogens for the first time; (2) the cytotoxicity of DMAEDM an...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2013.07.006
更新日期：2013-10-01 00:00:00
abstract：:Meta-analysis is a formalized method of combining results of different studies to provide conclusions about the effectiveness of a treatment modality. The aims of this study were to use meta-analysis to determine the clinical performance of posterior composite restorations using the assessment criteria of the USPHS gu...
journal_title：Journal of dentistry
pub_type： 杂志文章,meta分析
doi：10.1016/0300-5712(94)90143-0
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVES:Health condition of the gingival tissues contacting the surfaces of fixed prostheses is a result of multiple etiologic factors. The aim of the investigation discussed here was to evaluate the attachment and proliferation rate of cultured human epithelial cells on three commonly used restorative materials und...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2013.11.008
更新日期：2014-01-01 00:00:00
abstract：UNLABELLED:Soy beverages are water extracts of whole soybeans and are often promoted as a healthy alternative to bovine milk. Little analysis has been carried out to determine the effects of soy beverages on oral health, especially their potential acidogenicity. OBJECTIVES:The aim of this study was to determine the po...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.05.004
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVES:To investigate the influence of matrix and filler content on degradation resistance of an experimental pure-ormocer and an dimethacrylate-based composite derived from a commercially available material. MATERIALS AND METHODS:A dimethacrylate- Grandio (GR) and a model pure ormocer-based-matrix ORMOCER (ORM) w...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2011.10.012
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:Verify the influence of curing methods on contraction stress, stress rate, and degree of conversion (DC) of a restorative composite and on bond strength of composite restoratives. METHODS:For the stress test, composite (0.84 mm thick) was applied between two 5-mm diameter glass rods, mounted in a servohydra...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2006.10.003
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVES:To detect any differences in the propensity of unstimulated and stimulated, individual whole saliva to cause in vitro staining by chlorhexidine and tea. METHODS:Unstimulated and stimulated human saliva was collected on a daily basis and used to coat optically clear acrylic specimens. Specimens were subjecte...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(02)00053-2
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of shading technique and thickness on the color stability and translucency of translucent zirconia after coffee thermocycling. METHODS:Specimens in different thicknesses (1; 1.5; 2 mm) (n = 4 for each thickness) were sectioned from translucent preshaded zirconia (Pre) and externally sh...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.03.011
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:Evaluate erosive potential of beverages, using exposure times from 3 to 30 min, and to analyse the relationship between erosion and several drink parameters. METHODS:pH, calcium, phosphate and fluoride concentration, saturation, titratable-acidity to pH 5.5 and the viscosity of sixteen beverages were measur...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.09.004
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVES:To investigate, in a sample of probable sleep bruxers with and without temporomandibular disorder (TMD) pain, the presence and relationships between clinical jaw-muscle symptoms, and test their associations with jaw-muscle electromyographic (EMG) activity during sleep. METHODS:Pain, unpleasantness, tirednes...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2019.05.016
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to investigate the corrosion resistance of the prototype iron-platinum (FePt) magnets and non-encapsulated neodymium-iron-boron (NdFeB) magnets in three different pH environments. METHODS:The corrosion resistance of the magnets was studied using a corrosion indicator, the bre...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2004.02.007
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVES:Understanding the mechanical properties of dentine is of importance as adhesive restorative materials mainly achieve their bonding to the tooth structure through dentine. The current study measures the hardness and modulus of elasticity of primary molar dentine using an Ultra-Micro-Indentation System (UMIS),...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(03)00045-9
更新日期：2003-05-01 00:00:00
abstract：:An even fitting surface is essential to obtain and maintain a healthy oral mucosa in denture wearers. The present study was designed to clarify the relationship between the surface roughness of oral mucosa and its reproduction in the corresponding fitting surface of acrylic dentures. A silicone elastomer/epoxy replica...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(94)90201-1
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVES:The study aims at demonstrating the feasibility of a novel type of coupling-agent-free resin composite based on nano-porous fillers. METHODS:The fillers were obtained by ball-milling anodic alumina membranes. Composites were prepared with standard resin at maximum loading of 50% by weight. The resin matrix ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2013.12.001
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:This study compared the antibacterial activities of two dentin bonding systems (ABF, Kuraray and Reactmer Bond, Shofu) by a conventional agar well technique and a newly designed in vitro test using tooth model. METHODS:In the agar well technique, the test materials were filled in the wells of Muller Hinton a...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(03)00006-x
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:To evaluate a novel methodology using industrial scanners as a reference, and assess in vivo accuracy of 3 intraoral scanners (IOS) and conventional impressions. Further, to evaluate IOS precision in vivo. METHODS:Four reference-bodies were bonded to the buccal surfaces of upper premolars and incisors in fiv...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2017.12.006
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:To examine the removal rate of sound and carious dentine using bioactive glass air-abrasion and investigate abrasive particle retention of alumina and bioactive glass on abraded dentine. METHODS:Crushed bioactive glass was investigated as an alternative air-abrasive to alumina at air pressures of 138, 413 a...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2007.12.004
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:Quantification of collagen degradation is an important parameter to evaluate dentin caries progression or the efficacy of caries prevention aid. The aim of this study was to validate the simple light microscopic technique (LM) to evaluate collagen degradation by comparing with hydroxyproline assay techniqu...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2016.01.001
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVES:The aim of the present study is to investigate variables of the past caries experience as indicators of future caries in a Chinese child population. METHODS:Caries was recorded at baseline and 2 years later in 433, 6-7-year-old Chinese children. Correlation coefficients between variables of the past caries ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.12.010
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:to assess the expectations, perceptions and performance of different operators with varying backgrounds and training in the use of full-arch intraoral scanning (IOS). METHODS AND MATERIALS:Dentists (DENT), postgraduate dental students (DPG), and student prosthetists (PROS) were invited to join an IOS trainin...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2020.103572
更新日期：2020-12-29 00:00:00
abstract：UNLABELLED:Three types of fiber-reinforced composite (FRC) molar crowns were tested on their fracture resistance and marginal adaptation under simulated oral stress conditions. Two glass fiber systems, one processed with a vacuum/pressure system, the other by manual fiber adaptation, and a polyethylene fiber system wer...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(01)00007-0
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVES:This study evaluated the immediate and 6-month resin-dentin micro-bond strength (microTBS) of one-step self-etch systems (Adper Prompt L-Pop [AD] 3M ESPE; Xeno III [XE] Dentsply De Trey; iBond [iB] Heraeus Kulzer) under different application modes. MATERIALS AND METHODS:Dentin oclusal surfaces were exposed ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.01.018
更新日期：2008-05-01 00:00:00
abstract：UNLABELLED:Silver diammine fluoride (SDF) is used as an anticaries agent; however, its mode of action is uncertain, whether chemical, physical, mechanical or antibacterial. As a preliminary study, the effect of SDF on hydroxyapatite (HAp) and gelatin (as a chemically-representative protein) was examined. METHODS:2.5mg...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2011.06.008
更新日期：2011-09-01 00:00:00
