Abstract：
OBJECTIVE:Fibromyalgia (FM) is a chronic pain syndrome of unknown etiology, which affects predominantly women. Among the alterations that have been implicated in the pathophysiology of FM, there have been postulated disturbances in serotonin levels and metabolism, and their implication in symptoms. The aim of the present study was to assess the correlation levels between low levels of serotonin and severity of symptoms in FM. PATIENTS AND METHODS:We determined serotonin levels using an ELISA kit in serum from 38 FM patients and 25 healthy individual. Results were correlated with symptoms regarding pain, depression, impact of disease (FIQ) and age. RESULTS:Serotonin levels were decreased by 45% compared to healthy individual. An important correlation was observed between serotonin levels and predetermined parameters of pain, depression, FIQ and age. CONCLUSION:Serotonin levels are correlated with severity of FM. In addition, there is an interesting correlation between serotonin levels and age of patients.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Cordero MD,Alcocer-Gómez E,Cano-García FJ,de Miguel M,Sánchez-Alcázar JA,Moreno Fernández AMdoi
10.1016/j.medcli.2010.05.009subject
Has Abstractpub_date
2010-11-13 00:00:00pages
644-6issue
14eissn
0025-7753issn
1578-8989pii
S0025-7753(10)00612-3journal_volume
135pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：BACKGROUND AND OBJECTIVE:Patients identified as risk drinkers usually fill a questionnaire in order to assess their alcohol dependence. In our setting, the Münchner Alkoholismus Test (MALT) has been recommended, but there are not enough data about its validity and accuracy, particularly in women. The aim of this study ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13079611
更新日期：2005-10-08 00:00:00
abstract：:The gastric emptying of solids was evaluated with radionuclide techniques in 16 patients with reflux esophagitis, demonstrated by two of the following methods: endoscopy, pathology, and/or pH measurement. The percentage of radionuclide remaining within the stomach was 80.8 +/- 17% after 45 minutes, 63.3 +/- 10% after ...
journal_title：Medicina clinica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-09-30 00:00:00
abstract：:We assessed whether theophylline or budesonide (an inhaled corticosteroid) is the most adequate drug to be added to the treatment of patients insufficiently controlled with beta agonists (procaterol). Two comparable groups of nonatopic asthmatic adults (n = 24), aged between 16 and 66 years (42 +/- 17), were investiga...
journal_title：Medicina clinica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-11-24 00:00:00
abstract：BACKGROUND:The aim of the present was to study the cytohistology of the bone marrow in intravenous drug addicts (IVDA) and to analyze the possible differences according to the period of drug addiction. METHODS:A prospective study was performed in 60 IVDA patients previously untreated and distributed into three groups:...
journal_title：Medicina clinica
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-01-28 00:00:00
abstract：:In pseudohypoparathyroidism there is a resistance to the action of the parathormone in its target organs. Patients with this disease show clinical and laboratory data of hypoparathyroidism with normal or high levels of parathormone. Three types of pseudohypoparathyroidism are known according to the site in which the d...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-09-18 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Due to recent medical advances, patients with cystic fibrosis (CF) can expect longer survival rates and, as a result, face previously unreported complications such as osteoporosis. Our goal was to determine the mineral bone density in young adult patients with CF attended in the adult CF Unit, ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(04)74420-6
更新日期：2004-06-19 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To study the factors associated with prolonged hospitalization in patients admitted for acute heart failure (AHF) in Spanish short-stay units (SSUs). PATIENTS AND METHODS:This was a multicentre, multipurpose cohort study with prospective follow-up including all patients admitted for AHF in the...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medcli.2013.06.028
更新日期：2014-09-15 00:00:00
abstract：BACKGROUND:In the last few years a marked increase has been observed in the use of statistical techniques in biomedical publications. Some characteristics of the statistical quality of the first 100 articles consecutively published in 1993 in the section of originals and surveys of the journal MEDICINA CLINICA are pres...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1995-06-03 00:00:00
abstract：:The follow-up of the Mediterranean Diet (MD) has been associated with lower mortality and morbidity from cardiovascular diseases. However, it is important to evaluate the scientific evidence provided by published articles. Therefore, in order to analyze the literature on the overall effects of MD on intermediate and f...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2009.01.033
更新日期：2010-01-23 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Functional assessment is especially relevant in patients with cognitive impairment (CI). The Disability Assessment for Dementia (DAD) scale assesses functional ability and its use is becoming increasingly popular. This study aims to perform the translation and cultural adaptation of the DAD sca...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.03.029
更新日期：2017-09-20 00:00:00
abstract：BACKGROUND:Elevated blood urea nitrogen to serum albumin (BUN/ALB) ratio had been identified as an independent risk factor related to mortality in community-acquired and hospital-acquired pneumonia. This study aimed to investigate whether this clinical index can predict the clinical outcomes of E. coli bacteraemia. MA...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2020.06.060
更新日期：2020-10-12 00:00:00
abstract：:The electrocardiogram as a diagnostic aid in acute myocardial infarction of the right ventricle (AMI-RV) was studied prospectively in a group of 66 patients in our coronary unit. Diagnosis was AMI in all cases, divided into 29 (44%) with posterior-descending and 35 (53%) with anterior location. Electrocardiography was...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1981-09-25 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyz...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(06)72232-1
更新日期：2006-09-02 00:00:00
abstract：:We describe the experience of the Maxillofacial Surgery Service of the Gregorio Maranon University Hospital in attending the victims of the terrorist attack of 11 March, 2004 in Madrid. The most important types of cranio-maxillofacial injury treated that day, their mechanisms of production, and the organization of the...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13072640
更新日期：2005-03-01 00:00:00
abstract：:The REACH registry allows the degree of control of risk factors associated with atherothrombosis to be evaluated. Although 90% were taking at least one antihypertensive agent, hypertension was controlled in only 42.9% of the patients with vascular disease. This inadequate control may have multiple causes but the main ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(09)71754-3
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Self-care of health problems including self-medication, constitutes the most frequent response to the most common acute symptoms in several studies carried out in other countries. Indeed there are few data concerning the scope of self-care in Spain. METHODS:A telephone survey was carried out by a questionna...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-10-10 00:00:00
abstract：OBJECTIVES:To assess the immunological and virological markers as potential predictors of progression to death in HIV-1 infected < 12 months of age. PATIENTS AND METHODS:Forty-three HIV-1 infants < 12 months of age were evaluated. None of the children received antiviral treatment, neither their mothers during pregnanc...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-11-06 00:00:00
abstract：BACKGROUND:Our goal was to analyze the relationship of lipids and lipoproteins, APOE genotype and mutations of the LDL receptor gene with the prevalence of myocardial infarction (MI) in patients with familial hypercholesterolemia (FH) from a Southern European FH population. PATIENTS AND METHOD:We studied 108 heterozyg...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(02)72496-2
更新日期：2002-05-18 00:00:00
abstract：:Chronic kidney disease is common in people >65years of age. The development and improvement of dialysis techniques has allowed its generalisation to the entire population, when there is a situation of terminal nephropathy, without limit of use due to chronological age. Decision making in elderly patients with advanced...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2018.07.011
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Although elder abuse is not a new phenomenon, it remains hidden. There have been carried out various preliminary studies about the prevalence of elder abuse in different countries. The aim of this study is to estimate the prevalence of suspicion of elder abuse in old persons without cognitive i...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medcli.2012.09.048
更新日期：2013-12-21 00:00:00
abstract：:Heart failure (HF) is a cardiovascular disease with a permanent increase in prevalence, incidence and mortality. Current optimal therapies for HF are effective only for slowing, but not stopping, its progression. HF-related mortality is high, even at the time of the disease onset. Approximately 40% of HF-attributable ...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/s0025-7753(07)72555-1
更新日期：2007-02-24 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Fibromyalgia is considered as a combination of physical, psychological and social disabilities. The purpose of the present study was to determine the benefits of aerobic exercise program and progressive relaxation techniques on anxiety, quality of sleep, depression and quality of life in patien...
journal_title：Medicina clinica
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.medcli.2010.09.045
更新日期：2011-10-08 00:00:00
abstract：BACKGROUND AND OBJECTIVE:We aimed to test a new telerehabilitation device for stress urinary incontinence (SUI) in order to make an initial assessment of its effectiveness. PATIENTS AND METHOD:Randomized, controlled pilot study. INTERVENTION:experimental group (10 patients): pelvic floor muscle training, device train...
journal_title：Medicina clinica
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.medcli.2014.05.036
更新日期：2015-05-21 00:00:00
abstract：BACKGROUND AND OBJECTIVE:We aimed to determine whether measuring the hyperacute lipid profile helps to start a cholesterol-lowering therapy soon after an ischemic stroke. PATIENTS AND METHOD:72 ischemic stroke patients underwent lipid determinations at three times (hyperacute phase or arrival, second day and the third...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13072322
更新日期：2005-03-05 00:00:00
abstract：:We have evaluated 100 biopsies of temporal artery carried out in the Hospital La Paz from 1972 to 1986. On the basis of the histological result and the final diagnosis we divided the patients in five groups: I, temporal arteritis/polymyalgia rheumatica with positive biopsy, 11 cases; II, temporal arteritis without pol...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-01-28 00:00:00
abstract：BACKGROUND:To determine carboxyhemoglobin levels and to investigate carbon monoxide poisoning risk in children. PATIENTS AND METHODS:We determine carboxyhemoglobin blood levels by cooximetry in 65 children, between 15 days and 15 years attended in a pediatric emergency section. We analyze carbon monoxide risk factors ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1997-01-11 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The management of cardiac ischemic patients differs depending on their comorbidity. The Charlson Index (ChI) and its adaptations are well established and widely used tools to quantify a patient comorbidity. The aim of this study is to evaluate the influence of comorbidity quantified by the ChI ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13073218
更新日期：2005-04-02 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The REACH Registry is the largest worldwide designed to obtain information on cardiovascular risk factor control and preventive treatment in a population who have, or are at risk of having, symptoms of atherothrombosis. The objective of this study is to show the results of cardiovascular events...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2008.11.033
更新日期：2009-04-18 00:00:00
abstract：BACKGROUND:Using the data available from the Cancer Registry of Zaragoza, the incidence of breast cancer in women from 1961 to 1985 was analyzed with future evolution being predicted up to the year 2000. METHODS:The age, period and birth cohort effects, in addition to the place of residence (capital/rest of province) ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-05-29 00:00:00
abstract：:Bipolar disorder is a chronic and recurrent mood disorder, which may severely impact on the patient's global functioning. It has been estimated that approximately 1.6% of the population is affected. A long delay in diagnosis and an excessive disparity in the treatment of these patients have been detected. Within the Q...
journal_title：Medicina clinica
pub_type： 杂志文章,实务指引
doi：10.1016/j.medcli.2013.05.023
更新日期：2013-10-05 00:00:00
