Ocular adnexal lymphomas: a review.

Abstract:

:Ocular adnexal lymphomas comprise 1% to 2% of all non-Hodgkin lymphomas and about 8% of extranodal lymphomas. They are a heterogeneous group of malignancies, the majority of which are primary extranodal lymphoma with most (up to 80%) of the marginal zone of mucosa associated lymphoid tissue type (MALT lymphoma). This review will encompass the incidence, histology, immunophenotyping, recent advances in molecular and cytogenetics, clinical features including outcome, and prognostic factors. The association with Chlamydia psittaci and the very recently recognized occurrence in the context of IgG4-related sclerosing disease will be discussed. Finally, traditional (surgery, radiotherapy, chemotherapy) and newer forms of therapy (immunotherapy and radioimmunotherapy) will be reviewed.

journal_name

Adv Anat Pathol

authors

McKelvie PA

doi

10.1097/PAP.0b013e3181e4abdb

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

251-61

issue

4

eissn

1072-4109

issn

1533-4031

pii

00125480-201007000-00002

journal_volume

17

pub_type

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