Abstract：
INTRODUCTION:Glucagonomas are rare, frequently malignant tumours, arising from the Langerhans' islets of the pancreas. They usually secrete large amounts of glucagon that can cause a characteristic "glucagonoma syndrome", which includes necrolytic migratory erythema, glucose intolerance or diabetes, weight loss and sometimes, normochromic normocytic anaemia, stomatitis or cheilitis, diarrhoea or other digestive symptoms, thoromboembolism, hepatosplenomegaly, depression or other psychiatric and paraneoplastic symptoms. In certain cases, some or all glucagonoma symptoms may appear late, or even may be completely absent. CASE OUTLINE:The authors present a 43-year-old woman in whom an investigation for abdominal pain revealed a tumour of the body of the pancreas. During operation, the tumour of the body of the pancreas extending to the mesentery measuring 85 x 55 x 55 mm was excised. Histology and immunohistochemistry showed malignant glucagonoma, with co-expression of somatostatin in about 5% and pancreatic polypeptide in a few tumour cells. The recovery was uneventful. The patient stayed symptom-free with no signs of local recurrence or distant diseases 15 years after surgery. CONCLUSION:Glucagonoma syndrome may be absent in glucagonoma tumour patients so that in unclear pancreatic tumours the clinician should frequently request the serum hormone level (including glucagon) measurement by radioimmunoassay and the pathologist should perform immunohistochemistry investigation. Those two would probably result in discovery of more glucagonomas and other neuroendocrine tumours without characteristic clinical syndromes.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Colović R,Matić S,Micev M,Grubor N,Latincić Sdoi
10.2298/sarh1004244csubject
Has Abstractpub_date
2010-03-01 00:00:00pages
244-7issue
3-4eissn
0370-8179issn
2406-0895journal_volume
138pub_type
杂志文章abstract：:The study included 1,825 persons, aged from 18 to 65 years. A representative sample was formed of 1,325 persons who donated blood for the first time, and of 500 persons who donated blood five or more times till the moment of investigation. Among blood donors in the Republic of Serbia, regardless the number of blood do...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：INTRODUCTION:Neurofibromatosis type 1 is one of the most common genetically transmitted diseases with a high index of spontaneous mutations and extremely varied and unpredictable clinical manifestations. It is diagnosed by the existence of certain clinical criteria. The presence of numerous localised cutaneous neurofib...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0806295t
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:According to the literature, a fusiform aneurysm located in the cerebellopontine angle (CPA) is an extremely rare condition. CASE OUTLINE:We report a case of a 59-year-old patient with initial dizziness and left-sided sensorineural hearing loss that had gradually developed over six months. Vertebrobasilar...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1512731z
更新日期：2015-11-01 00:00:00
abstract：INTRODUCTION:Dyspnoea is a characteristic symptom of chronic obstructive pulmonary disease (COPD), which impairs everyday functioning of patients. OBJECTIVE:The aim of our study was to evaluate the relationship between the degree of dyspnoea of COPD patients and their health-related quality of life. METHOD:We measure...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0710547g
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:The obstruction of blood vessels or heart chambers with fat globules, reached by circulation, is fat embolism [1, 2]. Clinical manifestation of the presence of fat emboli in vital organs is Fat Embolism Syndrome (FES). This syndrome is characterized by neurologic, respiratory and cutaneous signs and differ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:In order to standardize language of medicine, it is essential to have a good command of ancient Greek and Latin. We cannot deny a huge impact of ancient Greek medicine on medical terminology. Compounds of Greek origin related to terms for organs, illnesses, inflammations, surgical procedures etc. have been listed as e...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0710606m
更新日期：2007-09-01 00:00:00
abstract：:Pharmacotherapy of autoimmune thyroid disease (AITD) is complex. Apart from the replacement hormone therapy, antithyroid agents, beta adrenoceptor blockers and other drugs, in regard to the present symptoms, it also includes the administration of glucocorticoids and immunosuppressive agents. Physiological actions of g...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh05s1067g
更新日期：2005-10-01 00:00:00
abstract：:In line with the fact that there is little information regarding drug facilitated sexual assault in national medical literature, the authors aimed to prepare a review of the phenomenon based on available international references. Therefore we offered a definition of the concept of sexual assault, and rape in particula...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：2007-03-01 00:00:00
abstract：:Etiopathogenesis of inflammatory processes of the urinary tract, mainly of obstructive uropathy and chronic pyelonephritis, is reviewed. The most frequent cause of obstruction is renal calculosis; in the pathogenesis of chronic pyelonephritis the following factors are of great importance: renal and urethral anomalies,...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：:Neurological diseases occur frequently in patients infected with human immunodeficiency virus (HIV). There are three main groups of central nervous system (CNS) dysfunction: (1) direct effects of HIV; (2) opportunistic infections; (3) opportunistic neoplasms. On the basis of clinical characteristics it is possible to ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1992-11-01 00:00:00
abstract：INTRODUCTION:Successful riddle solving requires recognition of the meaning of words, attention, concentration, memory, connectivity and analysis of riddle content, and sufficiently developed associative thinking. OBJECTIVE:The aim of the study was to determine the ability to solve riddles in stroke patients who do or ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2016-03-01 00:00:00
abstract：:The aim of our study was to examine the frequency of Chlamydia trachomatis infection in newborns by detecting specific antibodies, and to examine the Apgar score and the birth weight of Chlamydia trachomatis-antibody positive children. Fifty-two newborn infants were tested. High serum IgG chlamydial specific antibody ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION:Carotid endarterectomy is a safe and reliable surgical procedure to treat the narrowing of the internal carotid artery greater than 70%. One of the most serious complications of surgical wound after endarterectomy is an infection caused by methicillin-resistant Staphylococcus aureus (MRSA) which is accompa...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1104225p
更新日期：2011-03-01 00:00:00
abstract：:Doctor Svetislav Sp. Barjaktarovitsh (1893-1971), full professor of University School of Medicine in Belgrade, Head of the Department of Gynaecology and Obstetrics since its foundation, Director of the University Teaching Hospital of Gynaecology and Obstetrics from 1937 to 1948, was dismissed from University for polit...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:Reduced compound glutathione (GSH) in the lens has the function to protect the thiol group of lens proteins, and as a substrate of glutathione peroxidase (GPx) and glutathione S-transferase (GST). Protein containing thiol groups is significant for the normal function of lens epithelium, i.e. enzymes Na-K-A...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1210563k
更新日期：2012-09-01 00:00:00
abstract：:During the last several decades, cochlear implant has been fully recognized in treatment of severe hearing loss. Development of modern technology enabled inconceivable possibilities of technical qualities of the device as well as development of usable coding strategies, which led to extraordinary results in patient re...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0410302k
更新日期：2004-09-01 00:00:00
abstract：INTRODUCTION:Hemodynamic instability is a common occurrence during liver transplantation (LT). Hypotension and hemodynamic instability during graft reperfusion are most commonly consequences of the postreperfusion syndrome (PRS). CASE OUTLINE:In this report, we present a case of severe cardiovascular collapse leading ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1508467a
更新日期：2015-07-01 00:00:00
abstract：INTRODUCTION:More and more survival of newborns with small or extremely small body mass at birth, as well as increasing percent of prematurely born babies, have emphasized the significance of intracranial haemorrhage problem. Prematurely born infants are under increased risk for strabismus, amblyopia, blinding and hear...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1102006v
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:Despite numerous advances in medicine, the mortality rate of severe sepsis and septic shock remains high, 30-50%. New therapy strategies include: early goal-directed therapy, fluid replacement, early and appropriate antimicrobials, source of infection control, use of corticosteroids, vasopressors and inotr...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0806248j
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:Hepatic veno-occlusive disease (VOD) is a life threatening complication after stem cells transplantation (SCT). Its prediction, precise diagnosis and treatment remain unclear. OBJECTIVE:Our goals were to determine the incidence, outcome and changes in haemostatic parameters in patients with VOD. Also, we ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh10s1033j
更新日期：2010-01-01 00:00:00
abstract：:The recent data about the treatment of advanced breast cancer patients with synthetic LH-RH analogues are presented. Although synthetized 20 years ago, the agonistic analogues of LH-RH were introduced in clinical oncology recently. The inhibition of pituitary and gonadal function that occurs after chronic administrati...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Rubinstein-Taybi syndrome is a malformation occurring with approximate incidence of 1 per 10,000 live-born children. The diagnosis is usually based on specific facial dysmorphism in neonatal period, as well as on characteristic deformities of the hands and feet. Our study presents a male child who was diagnosed to hav...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh04s1109g
更新日期：2004-10-01 00:00:00
abstract：:The article deals with a successfull extirpation of femoral pseudotumour in a 53-year-old patient with severe haemophilia A (F VIII: C less than 1%) and an inhibitor to factor VIII. Such case is the first one reported in Yugoslavia. A combination of ultrasonography, computed axial tomography, angiography and Tc-99m la...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：INTRODUCTION:Considering operative treatment of various pathological conditions and traumatic injuries of extremities latissimus dorsi flap presents the most frequently used flap in reconstructive surgery. OBJECTIVE:The aim of this paper was to analyze anatomical characteristics of the vascular pedicle of the latissim...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1008449i
更新日期：2010-07-01 00:00:00
abstract：:During the space flight the cosmonaut is exposed to many stressogenic factors. The science is especially interested in microgravitation as an environmental element affecting the life of the crew in a cosmic vehicle, which is in contrast with human physiology in terrestrial conditions. The space medicine is interested ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：INTRODUCTION:Retinopathy of prematurity (ROP) is a multifactorial disease that occurs most frequently in very small and very sick preterm infants, and it has been identified as the major cause of childhood blindness. OBJECTIVE:The aim of this study was to evaluate ROP incidence and risk factors associated with varying...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：INTRODUCTION:It has been suggested that asthmatic patients may have a higher risk for oral diseases, both as a result of the medical condition and effects of medications. OBJECTIVE:The aim of the study was to determine the oral health status of children with asthma and to evaluate the oral health parameters according ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1510539m
更新日期：2015-09-01 00:00:00
abstract：:The drugs which are used today in medical treatment of asthma can be divided into two groups. The first group contains corticosteroides, as antiinflammatory agents. The second group contains bronchodilatators, usually used as symptomatic medicaments, and the third group are asthma--profilactics. The mechanism of activ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
abstract：INTRODUCTION:Root coverage supported with complete regeneration of lost periodontal tissues represents the ultimate goal of gingival recession treatment. OBJECTIVE:This study was designed to evaluate clinical effectiveness of platelet rich plasma gel (PRP) with connective tissue graft (CTG) in the treatment of gingiva...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0804095a
更新日期：2008-03-01 00:00:00
