Phase I/II trial of concurrent use of S-1 and radiation therapy for T2 glottic cancer.

abstract：BACKGROUND:The serum erythropoietin level increases markedly during chemotherapy for leukemia. A number of hypotheses have been built for the mechanism, none of them satisfactory. Difficulty in evaluating bone marrow activity hampers the elucidation. Therefore, we focused on patients who had non-hematological cancer an...

journal_title：Japanese journal of clinical oncology

authors： Sawabe Y,Takiguchi Y,Kikuno K,Iseki T,Ito J,Iida S,Kuriyama T,Yonemitsu H

更新日期：1998-03-01 00:00:00

abstract：:Cancer is already a well-recognized global phenomenon. The traditional approaches to cancer therapy have been surgery, radiotherapy and chemotherapy. These modalities have shown considerable promise and presently form cornerstones of management of most malignancies. However, these conventional approaches have associat...

journal_title：Japanese journal of clinical oncology

authors： Munshi A,Ni LH,Tiwana MS

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Chromosomal numerical abnormality (CNA) is a characteristic of breast cancer as with other common solid cancers. Multiple mammary carcinomas are also sometimes encountered in the ipsilateral breast. Deciding whether they are multicentric (arising independently) or multifocal (of the same origin) has been a c...

journal_title：Japanese journal of clinical oncology

authors： Nakamura R,Song JP,Isogaki J,Kitayama Y,Sugimura H

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma is a malignant bone tumor mainly affecting teenagers and young adults. Its main driver mutation, the EWS-FLI1 fusion gene, has been identified more than 20 years ago, whereas its other somatic mutations have been just recently reported. METHODS:In this study, we organized the somatic mutations...

journal_title：Japanese journal of clinical oncology

authors： Zhang Y,Song J,Shi Q,Song X,Shen L,Zhou J,Shao J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Apocrine carcinoma, a subtype of invasive ductal carcinoma of the breast, expresses androgen receptor (AR), but often lacks estrogen receptor (ER) and progesterone receptor (PgR). In the present study, the author immunohistochemically defined apocrine-type carcinoma as ER-/PgR-/AR+ invasive ductal carcinoma a...

journal_title：Japanese journal of clinical oncology

authors： Tsutsumi Y

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The consultation fee for outpatient radiotherapy was newly introduced in the national health insurance system in Japan in April 2012. We conducted a survey on the use of this consultation fee and its effect on clinical practices. METHODS:The health insurance committee of the Japanese Society of Therapeutic R...

journal_title：Japanese journal of clinical oncology

authors： Igaki H,Onishi H,Nakagawa K,Dokiya T,Nemoto K,Shigematsu N,Nishimura Y,Hiraoka M,Japanese Society for Therapeutic Radiology and Oncology Health Insurance Committee.

更新日期：2013-12-01 00:00:00

abstract：:Bone marrow transplantation (BMT) was started in Hokkaido in 1985. In the present report we have reviewed the clinical outcome of patients treated with BMT for hematological diseases in Hokkaido. Fifty-eight allogeneic and 19 autologous transplants were registered by December 1991. The underlying diseases consisted of...

journal_title：Japanese journal of clinical oncology

authors： Hashino S,Imamura M,Kasai M,Higa T,Naohara T,Sakamaki S,Matsunaga T,Kohgo Y,Kohda K,Nakazawa O

更新日期：1993-06-01 00:00:00

abstract：:The incidence of follicular lymphoma in Japan is far lower than that in western countries, and no large-scale clinicopathologic studies on this neoplasm have been conducted in Japan. We reviewed histopathological specimens from 118 of 135 patients who had been diagnosed as having follicular lymphoma between 1968 and 1...

journal_title：Japanese journal of clinical oncology

authors： Katsumata N,Matsuno Y,Nakayama H,Takenaka T,Kobayashi Y,Takeyama K,Narabayashi M,Fukushima T,Yokozawa T,Nakata M,Tajima K,Ikeda H,Tobinai K

更新日期：1996-12-01 00:00:00

abstract：:To evaluate the efficacy and toxicity of high-dose epirubicin (EPI) plus cyclophosphamide (CPA) therapy, a phase II study of EPI, 130 mg/m2, plus CPA, 1000 mg/m2, with G-CSF every 3 weeks was carried out for 51 advanced or recurrent breast cancer patients by the Japan Clinical Oncology Group (JCOG). Fifty out of the 5...

journal_title：Japanese journal of clinical oncology

authors： Takashima S,Saeki T,Adachi I,Watanabe T,Sasaki Y,Murai H,Tabei T,Ogita M,Sano M,Kanda K,Shimoyama M

更新日期：1997-10-01 00:00:00

abstract：:Immunohistochemical studies using antisera to keratin and secretory component (SC) and monoclonal antibody against leukocyte common antigen (LCA) were performed on 92 biopsy and autopsy specimens taken from 65 patients with nasopharyngeal carcinoma. Five biopsy specimens from malignant lymphoma of the nasopharynx and ...

journal_title：Japanese journal of clinical oncology

authors： Nomori H,Kameya T,Shimosato Y,Saito H,Ebihara S,Ono I

更新日期：1985-03-01 00:00:00

abstract：:Primary cardiac angiosarcoma is a rare, diagnostically elusive disease with a poor prognosis. In this report, we describe the case of a 56-year-old woman with a right atrial angiosarcoma. The patient presented with impending cardiac tamponade caused by right atrial perforation, but was misdiagnosed as a ruptured aneur...

journal_title：Japanese journal of clinical oncology

authors： Yoshitake I,Hata M,Sezai A,Niino T,Unosawa S,Shimura K,Kasamaki Y,Minami K

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. METHODS:Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular sc...

journal_title：Japanese journal of clinical oncology

authors： Morimoto M,Yoshioka Y,Kotsuma T,Adachi K,Shiomi H,Suzuki O,Seo Y,Koizumi M,Kagawa N,Kinoshita M,Hashimoto N,Ogawa K

更新日期：2013-08-01 00:00:00

abstract：:New drug delivery systems for cis-diamminedichloroplatinum (CDDP) incorporated into vehicles, such as polymethylmethacrylate (PMMA), fibrin glue (F.G.), alpha-tricalciumphosphate (TCP) and ethylenevinyleacetate copolymer (Polymer) were examined using a rat osteosarcoma model. The materials containing CDDP were directl...

journal_title：Japanese journal of clinical oncology

authors： Miura S,Mii Y,Miyauchi Y,Ohgushi H,Morishita T,Hohnoki K,Aoki M,Tamai S,Konishi Y

更新日期：1995-06-01 00:00:00

abstract：:This is a review regarding the current therapeutic strategies in the management of multiple myeloma. Due to the introduction of several new effective therapeutic agents, multiple myeloma is one of the most active and changing fields in clinical oncology. Multiple myeloma is caused by the expansion of monoclonal plasma...

journal_title：Japanese journal of clinical oncology

authors： Suzuki K

更新日期：2013-02-01 00:00:00

abstract：:We retrospectively analyzed the efficacy of chemotherapy in patients whose gastric cancer recurred after adjuvant chemotherapy with S-1. A total of 51 patients were evaluated. Twenty-one patients received S-1-containing chemotherapy as first-line treatment after recurrence [cohort A: S-1 plus cisplatin (n = 10), S-1 m...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Muro K,Ura T,Takahari D,Yokota T,Sawaki A,Kawai H,Ito S,Yamamura Y

更新日期：2008-11-01 00:00:00

abstract：:An analysis is presented of the histopathologic, clinical and prognostic features of malignant lymphomas (MLs) treated at the University of the Philippines-Philippine General Hospital Medical Center, Manila, between 1975 and 1981. There were 434 malignant lymphomas, constituting 3.86% of all cancers studied at this in...

journal_title：Japanese journal of clinical oncology

authors： Calderon B,Villalon A,Augustin B,Javier B,Zamuco J,Mori S

更新日期：1986-03-01 00:00:00

abstract：:Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-type lymphoma) is a rare thymic tumor, with only seven previous cases described worldwide to date. We describe the only case to have presented with pulmonary amyloid nodules. A 63-year-old Japanese female was found to have an anterior mediastinal tum...

journal_title：Japanese journal of clinical oncology

authors： Moriyama E,Yokose T,Kodama T,Matsuno Y,Hojo F,Takahashi K,Nagai K,Nishiwaki Y,Ochiai A

更新日期：2000-08-01 00:00:00

abstract：:Radical cystectomy with lymphadenectomy is the gold standard for treatment of invasive bladder cancer. However, the treatment alone does not always provide a satisfactory result for the disease extending outside the bladder. In this review we discuss several clinical issues in the diagnosis and treatment of this invas...

journal_title：Japanese journal of clinical oncology

authors： Tsukamoto T,Kitamura H,Takahashi A,Masumori N

更新日期：2004-06-01 00:00:00

abstract：Background:Stathmin has been found to be involved in malignant tumors; the aim of this study was to investigate the relationship between serum stathmin and clinico-pathological features of lung cancer. Methods:In three lung cancer cell lines, stathmin expression and its secretion level in the supernatant were examined...

journal_title：Japanese journal of clinical oncology

authors： Biaoxue R,Hua L,Tian F,Wenlong G

更新日期：2017-04-01 00:00:00

abstract：Background:Fluid collection (FC) of lymph or blood may accumulate at the site of excision after surgery for soft tissue sarcoma, with reported incidence rates from 10% to 36%. The purpose of this study is to analyze the impact of FC on local recurrence (LR) and wound complication rates after adjuvant postoperative radi...

journal_title：Japanese journal of clinical oncology

authors： Choi N,Kim JY,Yu T,Kang HC,Kim HS,Kim HJ,Kim IH

更新日期：2018-02-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：:Following a simple cholecystectomy, a 63-year-old woman with gallstones was histologically diagnosed as having minute squamous cell carcinoma of the gallbladder. A laparotomy revealed a small, firm nodule that appeared to be an adenoma, which was palpated in the fundus of the gallbladder. The resected gallbladder cont...

journal_title：Japanese journal of clinical oncology

authors： Roppongi T,Takeyoshi I,Ohwada S,Sato Y,Fujii T,Honma M,Morishita Y

更新日期：2000-01-01 00:00:00

abstract：:Reduced intensity stem cell transplantation (RIST) is a new approach of stem cell transplantation, which has shown promising features as reported in multiple phase I and II studies. Elderly patients, who are not eligible for conventional myeloablative hematopoietic stem cell transplantation (HSCT), are now treatable w...

journal_title：Japanese journal of clinical oncology

authors： Kami M,Makimoto A,Heike Y,Takaue Y

更新日期：2004-12-01 00:00:00

abstract：:In conclusion, a review of the epidemiology and pathology of latent prostatic cancer suggests this tumor to be the probable initial phase of a biological continuum that ends with metastatic cancer. Histological grade and tumor volume are highly correlated, as are histological grade and mitotic index. It has also been ...

journal_title：Japanese journal of clinical oncology

authors： Yatani R,Kusano I,Shiraishi T,Hayashi T,Stemmermann GN

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:To report the results of radiotherapy for patients with failure, adverse reactions or relative contraindications to the use of steroids or immunosuppressants, by using newly developed quantitative indexes. METHODS:Fourteen female and six male patients with Graves' ophthalmopathy were treated with radiothera...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Hareyama M,Oouchi A,Shidou M,Nagakura H,Morita K,Osanai H,Ohtsuka K,Hinoda Y

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Most cancer patients become increasingly anxious toward the end of their life. The objective of this study was to identify predictors of increased opioid dosage in the last week of a terminal cancer patient's life. METHODS:We retrospectively reviewed charts of patients who died in our palliative care unit. W...

journal_title：Japanese journal of clinical oncology

authors： Miura T,Matsumoto Y,Motonaga S,Hasuo H,Abe K,Kinoshita H

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:To improve palliative care practice, the need for patients-reported outcome measures is increasing globally. The Integrated Palliative care Outcome Scale (IPOS) is a streamlined outcome scale developed to comprehensively evaluate patients' distress. The goal of this study is to assess the reliability and val...

journal_title：Japanese journal of clinical oncology

authors： Sakurai H,Miyashita M,Imai K,Miyamoto S,Otani H,Oishi A,Kizawa Y,Matsushima E

更新日期：2019-03-01 00:00:00

abstract：:A 63-year-old man was admitted to the National Cancer Center Hospital on December 20, 1983 for a close examination of the abnormal shadows found in chest roentgenograms. Chest radiographs showed a massive right pleural effusion, a large tumor in the right hilar region and swelling of the left hilar nodes. Transcutaneo...

journal_title：Japanese journal of clinical oncology

authors： Akiba T,Saijo N,Miyamoto K,Sakurai M,Tamura T,Sasaki Y,Eguchi K,Shinkai T,Uei Y,Fujiwara Y

更新日期：1987-06-01 00:00:00

abstract：:During the period 1962-1986, 43 lung cancer patients, 2.3% of the 1,832 patients who underwent pulmonary resections at the National Cancer Center Hospital, Tokyo, had tumors greater than 10 cm in diameter. These 43 cancers were classified postsurgically according to the 1987 guidelines for TNM classification of malign...

journal_title：Japanese journal of clinical oncology

authors： Sano T,Naruke T,Kondo H,Goya T,Tsuchiya R,Suemasu K

更新日期：1990-12-01 00:00:00