Temazepam 'Planpak', a fixed-dose reduction regimen for withdrawing benzodiazepine hypnotics: results of a general practice survey.

Abstract:

:In a general practice survey of the use of Temazepam 'Planpak' ('Planpak'), 31 participating doctors completed questionnaires on 250 patients. Of these, 228 patients had been taking a variety of 8 benzodiazepine hypnotics prior to 'Planpak' therapy while 22 (8.8%) patients received 'Planpak' as a short course, without prior hypnotic therapy. Of the patients being weaned off benzodiazepines with 'Planpak', the majority had been on therapy for longer than 1 year (mean 5.36 +/- 5.58 years, range 0.08 to 22.9 years). Success (68%) or partial success (13%) was achieved in 81% of patients (95% confidence interval 77% to 86%) in terms of total abstinence from or reduced use of hypnotic for at least 1 month after 'Planpak' therapy. Outcome was not related statistically to gender, type, or duration of previous hypnotic therapy. Twenty-six patients received from one to three additional courses of 'Planpak' and 177 (71%) were not taking hypnotics at the time of the survey which represented a mean follow-up of 9.19 +/- 5.36 months (range 1.7 to 36.5 months).

journal_name

Curr Med Res Opin

authors

Drake J

doi

10.1185/03007999109111510

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

394-400

issue

6

eissn

0300-7995

issn

1473-4877

journal_volume

12

pub_type

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