The brain pattern of c-fos induction by two doses of amphetamine suggests different brain processing pathways and minor contribution of behavioural traits.

abstract：:Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and affects the CNS. Dystrophin is absent in muscle and CNS of both DMD patients and mdx mouse, a model of DMD. While the involvement of vascular compartment in DMD was poorly investigated, some studies suggested a role for mast cells (MC). Tryp...

journal_title：Neuroscience

authors： Nico B,Marzullo A,Corsi P,Vacca A,Roncali L,Ribatti D

更新日期：2004-01-01 00:00:00

abstract：:Olvanil ((N-vanillyl)-9-oleamide), a non-pungent transient receptor potential vanilloid type 1 agonist, desensitizes nociceptors and alleviates pain. But its molecular targets and signaling mechanisms are little known. Calcium influx through voltage-activated Ca(2+) channels plays an important role in neurotransmitter...

journal_title：Neuroscience

authors： Wu ZZ,Chen SR,Pan HL

更新日期：2006-08-11 00:00:00

abstract：:Compelling lines of evidence indicate that overexpression of dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) in subjects with trisomy 21 (Down syndrome[DS]) contributes to the abnormal structure and function of the DS brain. In the present study, we used a novel, phospho-dependent antibody r...

journal_title：Neuroscience

authors： Kida E,Walus M,Jarząbek K,Palminiello S,Albertini G,Rabe A,Hwang YW,Golabek AA

更新日期：2011-11-10 00:00:00

abstract：:NADPH-diaphorase histochemical staining demonstrated a distinct neural group that might synthesize nitric oxide in the lower brainstem of rats. The NADPH-diaphorase stain revealed a Golgi-like network in the dorsomedial spinal trigeminal nucleus oralis and rostrolateral solitary tract nucleus, whereas this network was...

journal_title：Neuroscience

authors： Takemura M,Wakisaka S,Yoshida A,Nagase Y,Bae YC,Shigenaga Y

更新日期：1994-08-01 00:00:00

abstract：:Inflammatory processes may play a critical role in the degeneration of basal forebrain cholinergic cells that underlies some of the cognitive impairments associated with Alzheimer's disease. In the present study, the proinflammagen lipopolysaccharide, from the cell wall of Gram-negative bacteria, was used to produce i...

journal_title：Neuroscience

authors： Willard LB,Hauss-Wegrzyniak B,Wenk GL

更新日期：1999-01-01 00:00:00

abstract：:Peripheral neuropathy represents an important complication of diabetes involving a spectrum of structural, functional and biochemical alterations in peripheral nerves. Recent observations obtained in our laboratory have shown that the levels of neuroactive steroids present in the sciatic nerve of rat raised diabetic b...

journal_title：Neuroscience

authors： Giatti S,Pesaresi M,Cavaletti G,Bianchi R,Carozzi V,Lombardi R,Maschi O,Lauria G,Garcia-Segura LM,Caruso D,Melcangi RC

更新日期：2009-12-01 00:00:00

abstract：:Recombinant human erythropoietin (EPO) has been successfully tested as neuroprotectant in brain injury models. The first large clinical trial with stroke patients, however, revealed negative results. Reasons are manifold and may include side-effects such as thrombotic complications or interactions with other medicatio...

journal_title：Neuroscience

authors： Rahimi Nedjat M,Wähmann M,Bächli H,Güresir E,Vatter H,Raabe A,Heimann A,Kempski O,Alessandri B

更新日期：2013-05-15 00:00:00

abstract：:The present study utilized an in vitro preparation of the rabbit carotid body, with tissue catecholamine stores labeled by incubation with 3H-tyrosine. The goal was to characterize pharmacologically the voltage-dependent Ca2+ channels present in the type I (glomus) cells of this arterial chemoreceptor organ, and to el...

journal_title：Neuroscience

authors： Obeso A,Rocher A,Fidone S,Gonzalez C

更新日期：1992-01-01 00:00:00

abstract：:The cerebral peptidergic caudodorsal cells of the freshwater snail Lymnaea stagnalis control egg laying and egg-laying behaviour by releasing peptides into (1) the haemolymph, from neurohaemal axon terminals in the periphery of the cerebral commissure and (2) the intercellular space of the central nervous system, from...

journal_title：Neuroscience

authors： Schmidt ED,Roubos EW

更新日期：1988-07-01 00:00:00

abstract：:In vivo microdialysis was used to measure the effects of partial deafferentation of cortical cholinergic inputs on acetylcholine efflux in young (four to seven months) and aged (24-28 months) male F344/BNNIA rats. Partial deafferentation was produced by bilateral infusions of the immunotoxin 192 immunoglobulin G-sapor...

journal_title：Neuroscience

authors： Fadel J,Sarter M,Bruno JP

更新日期：1999-03-01 00:00:00

abstract：:The functional changes of astrocytes are deeply involved in neurodegenerating processes of various CNS diseases. ATP is released during various neuronal damages such as brain ischemia and may control astrocyte functions. We examined the effect of ATP on the production of nitric oxide in the cultured astrocytes from ra...

journal_title：Neuroscience

authors： Murakami K,Nakamura Y,Yoneda Y

更新日期：2003-01-01 00:00:00

abstract：:The majority of work examining the nucleus accumbens core (NAc) has focused on functions pertaining to behaviors guided by appetitive outcomes. These studies have pointed to the NAc as being critical for motivating behavior toward desirable outcomes. For example, we have recently shown that lesions of the NAc impaired...

journal_title：Neuroscience

authors： Lichtenberg NT,Kashtelyan V,Burton AC,Bissonette GB,Roesch MR

更新日期：2014-01-31 00:00:00

abstract：:The efferent connections of the thalamic nucleus dorsointermedius posterior were studied in the pigeon. In pigeons, this thalamic nucleus receives both paleostriatal (basal ganglia) and cerebellar input and has been compared to nuclei of the mammalian thalamic ventral tier on this basis. The present results show that ...

journal_title：Neuroscience

authors： Kitt CA,Brauth SE

更新日期：1982-01-01 00:00:00

abstract：:Oxytocin-binding sites were detected by autoradiography on rat brain sections incubated in the presence of the [3H]oxytocin. These sites were characterized pharmacologically using quantitative autoradiography. High pressure liquid chromatography controls of the incubation media indicated that labelling was due to the ...

journal_title：Neuroscience

authors： Freund-Mercier MJ,Stoeckel ME,Palacios JM,Pazos A,Reichhart JM,Porte A,Richard P

更新日期：1987-02-01 00:00:00

abstract：:Cognitive aging affects episodic memory and executive functions, and these vulnerable domains are postulated to be modulated by endogenous and exogenous estrogen exposures. In midlife and late-life women without dementia, estrogen effects on cognition can be examined through associations with concentrations of serum e...

journal_title：Neuroscience

authors： Henderson VW,Popat RA

更新日期：2011-09-15 00:00:00

abstract：:We have recently shown that the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate enhances the depolarization induced, calcium dependent release of [3H]dopamine from cultured brain neurons in the rat. In the present study the effects of 12-O-tetradecanoyl-phorbol-13-acetate on the kinetic parameters of depolarizatio...

journal_title：Neuroscience

authors： Zurgil N,Yarom M,Zisapel N

更新日期：1986-12-01 00:00:00

abstract：:The extracellular matrix is a complex network of macromolecules including glycoproteins, polysaccharides and proteoglycans. Tenascin-R and chondroitin sulfate proteoglycans are essential components of hippocampal extracellular matrix co-localised in perineuronal nets on interneurons. Mutant mice deficient in expressio...

journal_title：Neuroscience

authors： Bukalo O,Schachner M,Dityatev A

更新日期：2001-01-01 00:00:00

abstract：:Specific high-affinity neurotensin binding sites were labeled in sections of the rat caudal brainstem using a monoiodinated ligand, and their distribution was examined by light microscopic radioautography after fixation with glutaraldehyde. In the medulla, labeled binding sites were mainly concentrated within the dors...

journal_title：Neuroscience

authors： Kessler JP,Moyse E,Kitabgi P,Vincent JP,Beaudet A

更新日期：1987-10-01 00:00:00

abstract：:Neurons containing melanin-concentrating hormone (MCH) in the lateral hypothalamic area (LH) have been shown to promote rapid eye movement sleep (REMs) in mice. However, the downstream neural pathways through which MCH neurons influence REMs remained unclear. Because MCH neurons are considered to be primarily inhibito...

journal_title：Neuroscience

authors： Kroeger D,Bandaru SS,Madara JC,Vetrivelan R

更新日期：2019-05-15 00:00:00

abstract：:This study was designed to examine the effect of voluntary exercise on hippocampal long-term potentiation (LTP) in morphine-dependent rats. The rats were randomly distributed into the saline-sedentary (Sal/Sed), the dependent-sedentary, the saline-exercise (Sal/Exc), and the dependent-exercise (D/Exc) groups. The Sal/...

journal_title：Neuroscience

authors： Miladi-Gorji H,Rashidy-Pour A,Fathollahi Y,Semnanian S,Jadidi M

更新日期：2014-01-03 00:00:00

abstract：:The neuromodulator adenosine maintains brain homeostasis and regulates complex behaviour via activation of inhibitory and excitatory adenosine receptors (ARs) in a brain region-specific manner. AR antagonists such as caffeine have been shown to ameliorate cognitive impairments in animal disease models but their effect...

journal_title：Neuroscience

authors： Singer P,McGarrity S,Shen HY,Boison D,Yee BK

更新日期：2012-06-28 00:00:00

abstract：:Experimental animal studies have demonstrated a number of receptor localizations on specific cortical afferents and neurons. The present study of human posterior cingulate cortex evaluates the laminar distributions of particular receptors and their likely association with components of the neuropil. Coverslip autoradi...

journal_title：Neuroscience

authors： Vogt BA,Plager MD,Crino PB,Bird ED

更新日期：1990-01-01 00:00:00

abstract：:Repeated nonreinforced preexposure to a stimulus interferes with the establishment of conditioned responding to this stimulus when it is subsequently paired with reinforcement. This stimulus-preexposure effect is known as latent inhibition (LI). Rather remarkably, LI appears to be resistant to the effects of numerous ...

journal_title：Neuroscience

authors： Schiller D,Weiner I

更新日期：2004-01-01 00:00:00

abstract：:Oscillatory activity is a prominent characteristic of electrophysiological recordings in the olfactory system and has been proposed to play a key role in encoding olfactory representations. Studies in several systems have shown that some aspects of information coding involve characteristics that intertwine spikes and ...

journal_title：Neuroscience

authors： Litaudon P,Garcia S,Buonviso N

更新日期：2008-10-15 00:00:00

abstract：:Recently, we reported that erythropoietin attenuates neonatal brain injury caused by focal cerebral ischemia. The long-term effects of erythropoietin on focal cerebral ischemia-induced injury to the developing brain and the potential gender differences in these long-term effects have not been studied in detail. The cu...

journal_title：Neuroscience

authors： Wen TC,Rogido M,Peng H,Genetta T,Moore J,Sola A

更新日期：2006-01-01 00:00:00

abstract：:We have examined the basic electrophysiology and pharmacology of cells in the anterior caudal lobe (CLa) of the mormyrid cerebellum. Intracellular recordings were performed in an in vitro slice preparation using the whole-cell patch recording method. The responses of cells to parallel fiber (PF) and climbing fiber (CF...

journal_title：Neuroscience

authors： Zhang Y,Magnus G,Han VZ

更新日期：2010-11-24 00:00:00

abstract：:Accumulating evidences indicate that ceramide is closely involved in apoptotic cell death in neurodegenerative disorders and aging. We examined ceramide levels in the cerebrospinal fluid (CSF) or brain tissues from patients with neurodegenerative disorders and the mechanism of how intra- and extracellular ceramide was...

journal_title：Neuroscience

authors： Satoi H,Tomimoto H,Ohtani R,Kitano T,Kondo T,Watanabe M,Oka N,Akiguchi I,Furuya S,Hirabayashi Y,Okazaki T

更新日期：2005-01-01 00:00:00

abstract：:Paclitaxel is one of the most commonly used anti-neoplastic drugs for the treatment of solid tumors. Unfortunately, its use is often associated with dose-limiting painful peripheral neuropathy and subsequent neuropathic pain that is resistant to standard analgesics. However, there are few clinically available drugs or...

journal_title：Neuroscience

authors： Kiya T,Kawamata T,Namiki A,Yamakage M

更新日期：2011-02-03 00:00:00

abstract：:In rat thalamic paraventricular nucleus of thalamus (PVT) neurons, activation of thyrotropin-releasing hormone (TRH) receptors enhances excitability via concurrent decrease in G protein-coupled inwardly-rectifying potassium (GIRK)-like and activation of transient receptor potential cation (TRPC)4/5-like cationic condu...

journal_title：Neuroscience

authors： Zhang L,Kolaj M,Renaud LP

更新日期：2015-12-17 00:00:00

abstract：:The purpose of this study was to determine the role of the axodendritic tree in the generation of bursting pacemaker activity in the identified Helix RPa1 neuron, which is homologous to the Aplysia R15 cell, and propagation of action potentials along the axons. In doing so, I used recording of RPa1 neuron electrical a...

journal_title：Neuroscience

authors： Kononenko NI

更新日期：2000-01-01 00:00:00