Global impact of rotavirus vaccines.

abstract：:As pregnant women are considered a high-risk group for severe influenza illness, current recommendations advise vaccination of all pregnant women with inactivated influenza vaccine. Nevertheless, rates of maternal influenza vaccination have historically been low, possibly reflecting ongoing concerns about vaccine safe...

journal_title：Expert review of vaccines

authors： Fell DB,Dodds L,MacDonald NE,Allen VM,McNeil S

更新日期：2013-12-01 00:00:00

abstract：:Interview by Jenaid Rees, Commissioning Editor Jeffrey Schlom obtained his PhD from Rutgers University (NJ, USA). After obtaining his PhD, he worked at Columbia University (NY, USA) before moving in 1973 to the National Cancer Institute, National Institutes of Health (MD, USA). Since then he has served as the Chief of...

journal_title：Expert review of vaccines

authors： Schlom J

更新日期：2013-10-01 00:00:00

abstract：:Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune adjuvants, improving the immune response elicited by coadministered vaccines. Combining CpG ODN with anthrax vaccine adsorbed (AVA), the licensed human vaccine, can increase the speed, magnitude and avidity of the resultant anti-ant...

journal_title：Expert review of vaccines

authors： Klinman DM

更新日期：2006-06-01 00:00:00

abstract：:The 11th Annual Conference on Vaccine Research, hosted by the National Foundation for Infectious Disease, attracted approximately 450 leaders in the fields of epidemiology, health economics, immunology and vaccinology, making it the largest scientific meeting devoted exclusively to vaccine research and technology. The...

journal_title：Expert review of vaccines

authors： O'Brien J

更新日期：2008-08-01 00:00:00

abstract：:Humanitarian aid workers regularly encounter the challenge of setting up functioning surveillance systems immediately after a disaster. Detecting potential outbreaks of diseases, such as cholera, that might arise from disturbed living conditions, displacement and lack of clean water and sanitation is, therefore, extre...

journal_title：Expert review of vaccines

authors： Chaignat CL,Monti V,Soepardi J,Petersen G,Sorensen E,Narain J,Kieny MP

更新日期：2008-05-01 00:00:00

abstract：:Buruli disease, caused by Mycobacterium ulcerans, is an emerging infectious disease in tropical areas, particularly West Africa, which can cause deep necrotizing skin lesions, called Buruli ulcer. Buruli disease affects all age groups but about 50% of the cases are diagnosed in children. There is no evidence that Buru...

journal_title：Expert review of vaccines

authors： Huygen K

更新日期：2003-08-01 00:00:00

abstract：:Newborns and infants are highly susceptible to infectious diseases, resulting in high mortality and morbidity, particularly in resource-poor settings. Many vaccines require several booster doses, resulting in an extensive vaccine schedule, and yet there is still inadequate protection from some of these diseases. This ...

journal_title：Expert review of vaccines

authors： Flanagan KL,Burl S,Lohman-Payne BL,Plebanski M

更新日期：2010-06-01 00:00:00

abstract：:Many vaccine candidates are highly purified, sometimes monomeric antigens and as a result, not very immunogenic. Antigen delivery systems optimize the presentation of antigens. They also play a major role in solving the problem of there being an increasing number of vaccines but limited opportunities in which to inclu...

journal_title：Expert review of vaccines

authors： Kersten G,Hirschberg H

更新日期：2004-08-01 00:00:00

abstract：:In addition to the use of traditional vaccines in the National Immunization Program, the introduction: of additional vaccines in Indonesia appears to be important to further reduce rates of childhood mortality. However, it typically takes at least two decades for additional vaccines to be introduced into the National ...

journal_title：Expert review of vaccines

authors： Suwantika AA,Postma MJ

更新日期：2014-12-01 00:00:00

abstract：:Several studies have identified an association between Pandemrix(TM), an AS03 adjuvanted pandemic influenza A(H1N1) vaccine, and narcolepsy, a rare and under-diagnosed sleep disorder with a median onset-to-diagnosis interval of ten years. This paper reviews potential sources of bias in published studies and aims to pr...

journal_title：Expert review of vaccines

authors： Wijnans L,Dodd C,de Ridder M,Romio S,Weibel D,Overeem S,Lammers GJ,Bonhoeffer J,Black S,Sturkenboom M

更新日期：2016-05-01 00:00:00

abstract：:With approximately 2.4 billion people at risk, Plasmodium falciparum malaria infection caused by an infectious bite of an Anopheles mosquito continues to be a major cause of mortality and morbidity, mainly in the tropics and subtropics. Measures to control the mosquito vector on a broad scale are expensive and need to...

journal_title：Expert review of vaccines

authors： Walther M

更新日期：2006-02-01 00:00:00

abstract：:Invasive meningococcal disease is a global public-health concern, with infants and adolescents bearing the majority of the disease burden. Vaccination is the most rational strategy to prevent meningococcal disease. Control of serogroup C disease has largely been achieved by the introduction of glycoconjugate meningoco...

journal_title：Expert review of vaccines

authors： Pace D

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:Syphilis, caused by the spirochete Treponema pallidum subspecies pallidum, continues to be a globally prevalent disease despite remaining susceptible to penicillin treatment. Syphilis vaccine development is a viable preventative approach that will serve to complement public health-oriented syphilis prevent...

journal_title：Expert review of vaccines

authors： Lithgow KV,Cameron CE

更新日期：2017-01-01 00:00:00

abstract：:The leishmaniases are a group of diseases caused by protozoa of the genus Leishmania which affects millions of people worldwide. The leishmaniases are transmitted to the vertebrate hosts by phlebotomine sand flies. In this review, we focus on clinical aspects of the leishmaniases and on the immune response against the...

journal_title：Expert review of vaccines

authors： Brodskyn C,de Oliveira CI,Barral A,Barral-Netto M

更新日期：2003-10-01 00:00:00

abstract：:To control the worldwide spread of HIV, a safe and effective prophylactic vaccine is urgently needed. Studies with the simian immunodeficiency virus demonstrated that a live attenuated virus can be effective as a vaccine, but serious concerns about the safety of such a vaccine virus have arisen. We propose a condition...

journal_title：Expert review of vaccines

authors： Das AT,Zhou X,Vink M,Klaver B,Berkhout B

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Patent and proprietary medicine vendors (PPMVs) are widespread in communities and can potentially be used to expand access to routine immunization especially in underserved areas. In this study, we aimed to assess their readiness to implement routine immunization in Kano, Nigeria and identify factors associa...

journal_title：Expert review of vaccines

authors： Adamu AA,Gadanya MA,Jalo RI,Uthman OA,Nnaji CA,Bello IW,Wiysonge CS

更新日期：2020-04-01 00:00:00

abstract：:This review deals with specific immunotherapy performed with pollen vaccines. Pollen allergens, the immunological mechanism of allergic inflammation and the mechanisms behind successful specific immunotherapy treatment of seasonal pollen allergy shall be discussed. The different approaches to develop improved regimes ...

journal_title：Expert review of vaccines

authors： Movérare R

更新日期：2003-02-01 00:00:00

abstract：:Psychological stress has been shown to be associated with poorer antibody levels following vaccination in both animals and humans, although the mechanisms underlying this relationship remain unclear. However, animal research has enabled investigation of how this relationship may be affected by the influence of individ...

journal_title：Expert review of vaccines

authors： Burns V

更新日期：2004-04-01 00:00:00

abstract：:Introduction Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), has quickly spread around the world. Areas covered This review will discuss the available immunologic and clinical evidence to support the benefit of the influenza, pneumococcal, and tuberculosis vaccines...

journal_title：Expert review of vaccines

authors： Sultana J,Mazzaglia G,Luxi N,Cancellieri A,Capuano A,Ferrajolo C,de Waure C,Ferlazzo G,Trifirò G

更新日期：2020-10-01 00:00:00

abstract：:Cancer immunotherapy has recently emerged as an important treatment modality. FDA approval of provenge, ipilimumab and pembrolizumab has started to deliver on the long awaited promise of cancer immunotherapy. Many new modalities of immunotherapies targeting cytotoxic T lymphocytes (CTLs) responses, such as adoptive ce...

journal_title：Expert review of vaccines

authors： Sharma RK,Chheda ZS,Jala VR,Haribabu B

更新日期：2015-04-01 00:00:00

abstract：:Baculovirus and insect cell culture technologies have mostly been limited to research laboratories for the transient expression of target proteins for drug development purposes. With the renaissance of the vaccine field and the regulatory acceptance of recombinant DNA technology, the baculovirus expression system has ...

journal_title：Expert review of vaccines

authors： Mena JA,Kamen AA

更新日期：2011-07-01 00:00:00

abstract：:The management of advanced prostate cancer, specifically metastatic castrate-resistant prostate cancer (mCRPC), remains a therapeutic challenge. Sipuleucel-T (Provenge; APC8015) was approved by the FDA in 2010 for the treatment of asymptomatic or minimally symptomatic mCRPC patients, and it remains the only FDA-approv...

journal_title：Expert review of vaccines

authors： Wei XX,Fong L,Small EJ

更新日期：2015-01-01 00:00:00

abstract：:Vaccine manufacturing processes are designed to meet present and upcoming challenges associated with a growing vaccine market and to include multi-use facilities offering a broad portfolio and faster reaction times in case of pandemics and emerging diseases. The final products, from whole viruses to recombinant viral ...

journal_title：Expert review of vaccines

authors： Gallo-Ramírez LE,Nikolay A,Genzel Y,Reichl U

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Streptococcus pneumoniae causes mucosal and invasive diseases with high morbidity and mortality. Introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) into routine infant immunization programs worldwide resulted in serotype 19A becoming a leading cause of the remaining pneumococcal disease bur...

journal_title：Expert review of vaccines

authors： Isturiz R,Sings HL,Hilton B,Arguedas A,Reinert RR,Jodar L

更新日期：2017-10-01 00:00:00

abstract：:Tumor vaccine has been studied extensively as an alternative or adjuvant therapy in the treatment of malignant tumors in the hope of prolonging the overall survival rates of cancer patients. The efficacy largely relies on the specificity of the target. In the last decade, many antibody epitopes, called mimotopes, have...

journal_title：Expert review of vaccines

authors： Zhao L,Liu Z,Fan D

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) regulate mucosal T-cell immunity and encounter several distinct bacteria of the gut flora, including lactobacilli. Gram-positive lactobacilli have been suggested to play an important role in exerting adjuvanticity effects on innate immune cells at mucosal sites. AIMS & METHODS:In the p...

journal_title：Expert review of vaccines

authors： Mohamadzadeh M,Klaenhammer TR

更新日期：2008-10-01 00:00:00

abstract：:Current influenza vaccines are primarily targeted to induce immunity to the influenza virus strain-specific hemagglutinin antigen and are not effective in controlling outbreaks of new pandemic viruses. An approach for developing universal vaccines is to present highly conserved antigenic epitopes in an immunogenic con...

journal_title：Expert review of vaccines

authors： Kang SM,Kim MC,Compans RW

更新日期：2012-08-01 00:00:00

abstract：:The aging process in humans is associated with a decrease in immune function (immunosenescence) and an increase in comorbid disorders. When combined with environmental factors this can lead to an increased risk and severity of infectious diseases. Diseases in older adults (>/=70 years) tend to be more severe and have ...

journal_title：Expert review of vaccines

authors： Maggi S

更新日期：2010-03-01 00:00:00

abstract：:Lassa virus (LASV) is the most prevalent arenavirus in West Africa and is responsible for several hundred thousand infections and thousands of deaths annually. The sizeable disease burden, numerous imported cases of Lassa fever (LF) and the possibility that LASV can be used as an agent of biological warfare make a str...

journal_title：Expert review of vaccines

authors： Lukashevich IS

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:There is a growing interest in developing curative strategies for HIV infection. Therapeutic vaccines are one of the most promising approaches. We will review the current knowledge and the new challenges in this research field. Areas covered: PubMed and ClinicalTrial.gov databases were searched to review t...

journal_title：Expert review of vaccines

authors： Leal L,Lucero C,Gatell JM,Gallart T,Plana M,García F

更新日期：2017-06-01 00:00:00