Abstract:
:In Brazil, the Unified National Health System (SUS) is responsible for the majority of kidney transplants. To maintain these interventions, the guidelines recommend the use of cyclosporine or tacrolimus, associated with corticosteroids and azathioprine or mycophenolate. Taking the perspective of the National Health System, an economic analysis was performed on the outpatient and hospital resources and medicines used by patient and therapeutic group. A cohort was constructed from 2000 to 2004, with 5,174 kidney transplant patients in use of cyclosporine or tacrolimus, identified by probabilistic record linkage from the National Health System. The cohort included 4,015 patients in use of cyclosporine and 1,159 using tacrolimus. The majority were males, age < 38 years, with nephritis, cardiovascular diseases, and indeterminate causes as the most frequent primary diagnoses. After 48 months of follow-up, the expenditures were higher for kidney transplants in hospitals in the Northeast, cadaver donors, patients in dialysis > 24 months before the transplant, and in the tacrolimus group. Total hospital and outpatient costs and expenditure on medication were higher in patients on tacrolimus as compared to the cyclosporine group.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Guerra Junior AA,Acúrcio Fde A,Andrade EI,Cherchiglia ML,Cesar CC,Queiroz OV,Silva GDdoi
10.1590/s0102-311x2010000100017subject
Has Abstractpub_date
2010-01-01 00:00:00pages
163-74issue
1eissn
0102-311Xissn
1678-4464pii
S0102-311X2010000100017journal_volume
26pub_type
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