Endothelial progenitor cells--an evolving story.

abstract：:The maturational changes in tissue water spaces and in the fractional exclusion of albumin from the interstitial gel were studied in the developing rabbit using multiple radioactive tracers. Total tissue water and extracellular water decrease with age in all organs studied. Intracellular water decreases in the heart a...

journal_title：Microvascular research

authors： Kwong MS,Egan EA,Ferguson W

更新日期：1986-05-01 00:00:00

abstract：:The retina provides a window to study the pathophysiology of cerebrovascular diseases. Pathological retinal microvascular changes may reflect microangiopathic processes in the brain. Recent advances in optical imaging techniques have enabled the imaging of the retinal microvasculature at the capillary level, and the g...

journal_title：Microvascular research

authors： Jiang H,Debuc DC,Rundek T,Lam BL,Wright CB,Shen M,Tao A,Wang J

更新日期：2013-09-01 00:00:00

abstract：:Innate immunity is characterized by the coordinated activity of multiple leukocytes mobilizing at or near the site of tissue injury. Slow rolling and/or adherent leukocytes have been shown to hydrodynamically recruit free-stream leukocytes to a model of inflamed tissue. In this paper, we numerically investigate the hy...

journal_title：Microvascular research

authors： Subramaniam DR,Gee DJ

更新日期：2018-01-01 00:00:00

abstract：:Methods currently available for the examination of the retinal vasculature of laboratory animals have significant drawbacks. Fluorescein angiography of rodent eyes is hampered by a poor view of the peripheral retina and difficulty in performing fundus photography. Methods of staining or filling retinal vessels are unr...

journal_title：Microvascular research

authors： D'Amato R,Wesolowski E,Smith LE

更新日期：1993-09-01 00:00:00

abstract：:Alterations in the reactivity of arterioles to vasodilator agonists were assessed in the skeletal muscle microcirculation of age-matched, normotensive male Sprague-Dawley rats fed either a high salt (4% NaCl, HS) or a low salt (0.4% NaCl, LS) diet and in reduced renal mass hypertensive rats on a high salt diet (HSRRM)...

journal_title：Microvascular research

authors： Frisbee JC,Lombard JH

更新日期：1998-11-01 00:00:00

abstract：:Using the laser-Doppler method we measured blood flow on the nailfold skin to compare the reactivity of cutaneous microcirculation in three groups of normotensive subjects: 11 subjects with a familial predisposition to hypertension without a previous record of high blood pressure, 6 predisposed subjects with a previou...

journal_title：Microvascular research

authors： Maver J,Strucl M

更新日期：2000-11-01 00:00:00

abstract：:Nitrate supplementation in the form of beetroot juice has been shown to increase nitric oxide (NO) where nitrate can be reduced to nitrite and, subsequently, to NO through both nitric oxide synthase (NOS)-dependent and -independent pathways. We tested the hypothesis that nitrate supplementation would augment the NO co...

journal_title：Microvascular research

authors： Keen JT,Levitt EL,Hodges GJ,Wong BJ

更新日期：2015-03-01 00:00:00

abstract：:Immunological studies of human endothelial cells have been performed almost entirely on endothelial cells (EC) derived from foetal (umbilical vein) or adult (aorta) large vessels. Immunologically these EC have in common the fact that they are negative for major histocompatibility complex (MHC) class II antigens (HLA-D...

journal_title：Microvascular research

authors： McDouall RM,Yacoub M,Rose ML

更新日期：1996-03-01 00:00:00

abstract：:Diabetes mellitus (DM) leads to the development of microvascular diseases and is associated with impaired angiogenesis. The presence of vascular endothelial growth factor (VEGF) can block PDGF-BB dependent regulation of neovascularization and vessel normalization. We tested the hypothesis that the inhibition of VEGF i...

journal_title：Microvascular research

authors： Xiao L,Yan K,Yang Y,Chen N,Li Y,Deng X,Wang L,Liu Y,Mu L,Li R,Luo M,Ren M,Wu J

更新日期：2016-05-01 00:00:00

abstract：UNLABELLED:Metabolic syndrome (MetS) increases the risk of the subsequent development of cardiovascular disease. This study aimed to determine if the harmonic indexes of finger photoplethysmography (PPG) waveforms can be used to discriminate different arterial pulse transmission conditions between MetS and healthy subj...

journal_title：Microvascular research

authors： Chang YW,Hsiu H,Yang SH,Fang WH,Tsai HC

更新日期：2016-07-01 00:00:00

abstract：:Electrophysiological characteristics of cultured human umbilical vein endothelial cells (HUVEC) were determined using the patch-clamp technique in the whole cell configuration. In isolated cells, membrane potential, capacitance, and input resistance were (Mean +/- SD) - 16.3 +/- 12.7 mV, 53.9 +/- 26 pF, and 2.3 +/- 1....

journal_title：Microvascular research

authors： Vargas FF,Caviedes PF,Grant DS

更新日期：1994-03-01 00:00:00

abstract：:Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis in the mammalian eye, suggesting that loss of PEDF is implicated in the pathogenesis of proliferative diabetic retinopathy. However, a role for PEDF in early diabetic retinopathy remains to be elucidated. Since oxidative stress is thought t...

journal_title：Microvascular research

authors： Amano S,Yamagishi S,Inagaki Y,Nakamura K,Takeuchi M,Inoue H,Imaizumi T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Angiogenin levels are increased in children and adolescent patients with type 1 diabetes, regardless of the extent of diabetic microangiopathy. However, little is known about the angiogenin concentrations in adults with type 1 diabetes. Thus we studied its level in middle aged subjects with the presence of d...

journal_title：Microvascular research

authors： Neubauer-Geryk J,Kozera GM,Wolnik B,Szczyrba S,Nyka WM,Bieniaszewski L

更新日期：2012-11-01 00:00:00

abstract：:It is generally assumed that when a muscle is shortened or extended the total length of capillaries does not change, implying that capillaries are nondistensible, longitudinally. On the basis of stereological estimates of capillary anisotropy versus sarcomere length, we propose that as long as capillaries are in a tor...

journal_title：Microvascular research

authors： Ellis CG,Mathieu-Costello O,Potter RF,MacDonald IC,Groom AC

更新日期：1990-07-01 00:00:00

abstract：:The role of VEGF during development and in pathology is well known, but its function in normal adult tissues is poorly understood. Adverse effects associated with the use of anti-angiogenic therapies targeting VEGF in human pathologies have begun to reveal potential functions of VEGF in quiescent vasculature. Further ...

journal_title：Microvascular research

authors： Maharaj AS,D'Amore PA

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Understanding the differences in skin blood flow (SBF) on the plantar and dorsal foot in people with diabetes mellitus (DM) may help to assess the influence of diabetes and neuropathy on microvascular dysfunction and risks of diabetic foot ulcers in this population. However, there is no study comparing SBF o...

journal_title：Microvascular research

authors： Jan YK,Liao F,Cheing GLY,Pu F,Ren W,Choi HMC

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Vascular hyporeactivity in severe hemorrhagic shock could induce refractory hypotension and is an important cause of death. The global acute inflammatory response induced in shock triggers the over-expression of reactive oxygen species, NO, ET1 and TNF-α, which play essential roles in the pathology of vascul...

journal_title：Microvascular research

authors： Chen D,Song MQ,Liu YJ,Xue YK,Cheng P,Zheng H,Chen LB

更新日期：2016-05-01 00:00:00

abstract：:Endothelial cells represent one of the critical cellular elements in tumor microenvironment playing a crucial role in the growth and progression of cancer through controlling angiogenesis. Vascular endothelial growth factor (VEGF) produced from tumor cells is essential for the expansion of breast cancer and may functi...

journal_title：Microvascular research

authors： Alvarez-García V,González A,Alonso-González C,Martínez-Campa C,Cos S

更新日期：2013-05-01 00:00:00

abstract：:The Raynaud's phenomenon often accompanies systemic rheumatic diseases and is also known as a vascular side effect of chemotherapy. Therapy of the Raynaud's phenomenon with nitrates or calcium-channel-blockers is rarely beneficial. In contrast, the PDE-V-inhibitor sildenafil seems to be effective in these patients. Fo...

journal_title：Microvascular research

authors： Baumhaekel M,Scheffler P,Boehm M

更新日期：2005-05-01 00:00:00

abstract：:We tested the hypothesis that the endothelial nitric oxide (NO)-soluble guanylyl cyclase system is involved in atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) mediated regulation of coronary and peripheral vascular resistance. Rat hearts were perfused via the aorta at constant flow and the effect...

journal_title：Microvascular research

authors： Brunner F,Wölkart G

更新日期：2001-01-01 00:00:00

abstract：:This study aims to assess the relationship between spontaneous oscillations in changes in cerebral tissue oxyhemoglobin concentrations (Delta [HbO2]) and arterial blood pressure (ABP) signals in healthy elderly subjects during the resting state using wavelet coherence analysis. Continuous recordings of near-infrared s...

journal_title：Microvascular research

authors： Cui R,Zhang M,Li Z,Xin Q,Lu L,Zhou W,Han Q,Gao Y

更新日期：2014-05-01 00:00:00

abstract：:The cytoskeleton is vital to the function of virtually all cell types in the organism as it is required for cell division, cell motility, endo- or exocytosis and the maintenance of cell shape. Endothelial cells, lining the inner surface of the blood vessels, exploit cytoskeletal elements to ensure the integrity of cel...

journal_title：Microvascular research

authors： Bogatcheva NV,Verin AD

更新日期：2008-11-01 00:00:00

abstract：:Reduced lung capillary expression of angiotensin I-converting enzyme (ACE), a key enzyme in cardiovascular pathophysiology, and of caveolin-1, an important regulator of endothelial cell signalling, has been demonstrated in various models of pulmonary arterial hypertension (PAH). We addressed the relationship between P...

journal_title：Microvascular research

authors： Maniatis NA,Balyasnikova IV,Metzger R,Castellon M,Visintine DJ,Schwartz DE,Minshall RD,Danilov SM

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Leukocytes play a key role in the early response to tissue injury/infection resulting from physical, chemical or biological stimuli. This process involves the initiation of the leukocyte adhesion cascade mediated by a series of interactions between receptors and ligands on the endothelium and the leukocytes. ...

journal_title：Microvascular research

authors： Lamberti G,Tang Y,Prabhakarpandian B,Wang Y,Pant K,Kiani MF,Wang B

更新日期：2013-09-01 00:00:00

abstract：:Patients with diabetic polyneuropathy are known to have an impaired neurovascular reflex arc compared to healthy controls. This is seen in a delayed decrease in microcirculation of the ipsilateral hand after cooling of the contralateral hand. The aim of this pilot study was to investigate whether intravenous alpha-lip...

journal_title：Microvascular research

authors： Haak ES,Usadel KH,Kohleisen M,Yilmaz A,Kusterer K,Haak T

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Tissue ischemia and reperfusion (I/R) affects blood flow restoration and oxygen delivery to the damaged tissues contributing to tissue morbidity and microcirculatory compromise. Pulsed acoustic cellular expression (PACE) technology is known to support tissue neovascularization. The aim of this study was to t...

journal_title：Microvascular research

authors： Krokowicz L,Klimczak A,Cwykiel J,Mielniczuk M,Grykien C,Siemionow M

更新日期：2012-03-01 00:00:00

abstract：:The purpose of this study was to elucidate the mechanism by which bradykinin (BK) enhances prostacyclin (PGI(2)) production in human umbilical vein endothelial cells (HUVEC). BK-induced enhancement of PGI(2) synthesis was observed in a dose- and time-dependent manner, and it also increased [Ca(2+)](i) followed by enha...

journal_title：Microvascular research

authors： Higaki T,Sawada S,Kono Y,Imamura H,Tada Y,Yamasaki S,Toratani A,Sato T,Komatsu S,Akamatsu N,Tamagaki T,Tsuda Y,Tsuji H,Nakagawa M

更新日期：1999-09-01 00:00:00

abstract：:A theoretical model, appropriate for data interpretation, is presented for the transcapillary fluid exchange and associated intraluminal hydrodynamic and solute transport occurring in the microocclusion of single capillaries. This analysis describes the spatial and temporal behavior of the intraluminal flow. A compari...

journal_title：Microvascular research

authors： Blake TR,Gross JF

更新日期：1983-03-01 00:00:00

abstract：:Local skin heating to 42°C causes rapid increases in cutaneous perfusion (initial peak), followed by a brief nadir and subsequent sustained elevation (plateau). Several studies have demonstrated that nitric oxide synthase (NOS) largely contributes to the plateau response during local heating. In this study, we tested ...

journal_title：Microvascular research

authors： Fujii N,Halili L,Nishiyasu T,Kenny GP

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The burden of type 1 diabetes (T1D) is growing worldwide, stressing the requirement to limit the threat of its long-term complications. In this regard, the development of methods for the early diagnosis and non-invasive monitoring of vascular abnormalities is widely recognized as one of the greatest prioriti...

journal_title：Microvascular research

authors： Sorelli M,Francia P,Bocchi L,De Bellis A,Anichini R

更新日期：2019-07-01 00:00:00