Abstract:
UNLABELLED:Metabolic syndrome (MetS) increases the risk of the subsequent development of cardiovascular disease. This study aimed to determine if the harmonic indexes of finger photoplethysmography (PPG) waveforms can be used to discriminate different arterial pulse transmission conditions between MetS and healthy subjects. Three-minute PPG signals were obtained in 65 subjects, who were assigned to 3 age-matched groups (MS, with no less than three MetS factors; pre-MS, with one or two MetS factors; CONTROL:with no MetS factor). FDT (foot delay time) and amplitude proportions (Cn) and their standard deviations (SDn) and coefficients of variations (CVn) were calculated for harmonics 1 to 10 of the PPG waveform. FDT was smaller in MS than in CONTROL. C1 and C2 values were significantly smaller, whereas C4-C9 values were significantly or appeared to be larger in MS than in pre-MS. Most of the SDn and CVn values were largest in MS. This study is the first to demonstrate that harmonic-analysis indexes of the beat-to-beat PPG waveform can provide information about MetS-induced changes in the arterial pulse transmission and cardiovascular regulatory activities. The present findings may therefore be useful in developing a noninvasive and easy-to-perform technique that could improve the early detection of cardiovascular diseases.
journal_name
Microvasc Resjournal_title
Microvascular researchauthors
Chang YW,Hsiu H,Yang SH,Fang WH,Tsai HCdoi
10.1016/j.mvr.2016.04.001subject
Has Abstractpub_date
2016-07-01 00:00:00pages
80-7eissn
0026-2862issn
1095-9319pii
S0026-2862(16)30025-5journal_volume
106pub_type
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