Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study.

abstract：:Risperidone has been shown to improve serious behavioral problems in children with autism. Here we asked whether risperidone-associated improvement was related to changes in concentrations of inflammatory molecules in the serum of these subjects. Seven molecules were identified as worthy of further assessment by perfo...

journal_title：Journal of child and adolescent psychopharmacology

authors： Tobiasova Z,van der Lingen KH,Scahill L,Leckman JF,Zhang Y,Chae W,McCracken JT,McDougle CJ,Vitiello B,Tierney E,Aman MG,Arnold LE,Katsovich L,Hoekstra PJ,Volkmar F,Bothwell AL,Kawikova I

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to retrospectively review a large sample of children and adolescents with pervasive developmental disorders (PDDs) treated with open-label guanfacine in order to gather preliminary data as to its effectiveness and safety. METHOD:Eighty (80) subjects with PDDs (10 females, 70 males) ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Posey DJ,Puntney JI,Sasher TM,Kem DL,McDougle CJ

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Few studies of psychotropic medication use among children and adolescents address the effectiveness of this medication, as it is typically used in naturalistic treatment settings. The objective of this study was to investigate psychotropic medication use among children and adolescents treated in system of car...

journal_title：Journal of child and adolescent psychopharmacology

authors： Drilea SK,Jowers K,Lichtenstein C,Hale M,Blau G,Stromberg S

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:This study examines cardiovascular (CV) effects of guanfacine immediate-release (GUAN-IR), dexmethylphenidate extended-release (DMPH), and their combination (COMB) during acute and long-term treatment of youth with attention-deficit/hyperactivity disorder. METHODS:Two hundred seven participants aged 7-14 ye...

journal_title：Journal of child and adolescent psychopharmacology

authors： Sayer GR,McGough JJ,Levitt J,Cowen J,Sturm A,Castelo E,McCracken JT

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To evaluate measures of sleep (exploratory endpoints) in two pivotal studies of a multilayer bead extended-release methylphenidate (MPH-MLR) treatment of attention-deficit/hyperactivity disorder in children. METHODS:Study 1 evaluated the time course of response to MPH-MLR (n = 26) patients in an analog class...

journal_title：Journal of child and adolescent psychopharmacology

authors： Owens J,Weiss M,Nordbrock E,Mattingly G,Wigal S,Greenhill LL,Chang WW,Childress A,Kupper RJ,Adjei A

更新日期：2016-12-01 00:00:00

abstract：:A 10-year-old boy with a history of heart transplantation had a potentially life-threatening decrease in his cyclosporine (CSA) blood levels during administration of bupropion. Subsequently he had an increase in CSA levels while receiving methylphenidate. These occurrences represent potential drug-drug interactions in...

journal_title：Journal of child and adolescent psychopharmacology

authors： Lewis BR,Aoun SL,Bernstein GA,Crow SJ

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Although recent studies and meta-analyses confirm the efficacy of antidepressants in the acute phase of treatment for adolescent depression, there are few data available to allow assessment of the value of continued use of antidepressants in depressed adolescents after acute response. This study examines the ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cheung A,Kusumakar V,Kutcher S,Dubo E,Garland J,Weiss M,Kiss A,Levitt A

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:Studies have primarily focused on adverse life events (ALEs) as potential causes rather than as outcomes of pediatric depression. The current study prospectively examines ALEs in a sample of youth with attention-deficit/hyperactivity disorders (ADHD) to determine whether having a major depressive disorder (M...

journal_title：Journal of child and adolescent psychopharmacology

authors： Daviss WB,Diler R

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:The expanded use of antidepressants in youth has been the subject of numerous studies and some concerns in recent years. This study describes prescription patterns of antidepressants (ATD) for youths in Germany for the years 2000-2003 and includes prescription use of St. John's Wort. METHODS:Prescription dat...

journal_title：Journal of child and adolescent psychopharmacology

authors： Fegert JM,Kölch M,Zito JM,Glaeske G,Janhsen K

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To describe the methodological challenges and decisions made in developing a multisite, controlled study of risperidone in children and adolescents with autism. METHODS:Review the design considerations for clinical trials in children with autistic disorder accompanied by severe tantrums, aggressive and/or se...

journal_title：Journal of child and adolescent psychopharmacology

authors： Scahill L,McCracken J,McDougle CJ,Aman M,Arnold LE,Tierney E,Cronin P,Davies M,Ghuman J,Gonzalez N,Koenig K,Lindsay R,Martin A,McGough J,Posey DJ,Swiezy N,Volkmar F,Ritz L,Vitiello B

更新日期：2001-01-01 00:00:00

abstract：:The prevalence and treatment of behavioral and mental illnesses in the adolescent population are increasing, and many of the medications used are continued into adulthood. Increased vigilance is necessary when caring for this population to prevent side effects and drug interactions. In this short communication, we pre...

journal_title：Journal of child and adolescent psychopharmacology

authors： George AK,Kunwar AR,Awasthi A

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to describe the special considerations for building rapport and establishing a therapeutic alliance when conducting mental health evaluations for children and adolescents via videoconferencing. METHODS:The authors review the literature and describe their experience in conducting...

journal_title：Journal of child and adolescent psychopharmacology

authors： Goldstein F,Glueck D

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:In the four-site Treatment of Severe Childhood Aggression (TOSCA) study, addition of risperidone to stimulant and parent training moderately improved parent-rated disruptive behavior disorder (DBD) symptoms. This secondary study explores outcomes other than DBD and attention-deficit/hyperactivity disorder (AD...

journal_title：Journal of child and adolescent psychopharmacology

authors： Arnold LE,Gadow KD,Farmer CA,Findling RL,Bukstein O,Molina BS,Brown NV,Li X,Rundberg-Rivera EV,Bangalore S,Buchan-Page K,Hurt EA,Rice R,McNamara NK,Aman MG

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperkinetic conduct disorder (HCD) has been identified as a common psychiatric diagnosis among children and adolescents. This disorder affects many life aspects of both child and family. The aim of this study was to examine the efficacy of the selective norepinephrine reuptake inhibitor (SNRI), ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Mozes T,Meiri G,Ben-Amity G,Sabbagh M,Weizman A

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this article was to systematically review the literature on stimulant and atomoxetine combination therapy, in particular: 1) Characteristics of patients with attention-deficit/hyperactivity disorder (ADHD) given combination therapy, 2) treatment strategies used, 3) efficacy and effectiveness, a...

journal_title：Journal of child and adolescent psychopharmacology

authors： Treuer T,Gau SS,Méndez L,Montgomery W,Monk JA,Altin M,Wu S,Lin CC,Dueñas HJ

更新日期：2013-04-01 00:00:00

abstract：:The autism spectrum disorders (ASDs) can present with symptoms commonly found in mood and anxiety disorders. The Social Communication Questionnaire (SCQ), Children's Communication Checklist (CCC-2), and the Social Reciprocity Scale (SRS) were used to screen children in a mood disorders research clinic setting for symp...

journal_title：Journal of child and adolescent psychopharmacology

authors： Towbin KE,Pradella A,Gorrindo T,Pine DS,Leibenluft E

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Recent research suggests that not only parental psychopathology, but also parenting practices, have a role to play in the development of child posttraumatic stress symptoms (PTSS) following a natural disaster. The current study aimed to investigate the relationship between parents' perceptions of their parent...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cobham VE,McDermott B

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:This study examined the effects of pediatric anxiety and its interaction with gender on reward processes. Based on the purported greater sensitivity to risk in females than males and the propensity for risk aversion in anxiety, clinical anxiety and female gender were hypothesized to act synergistically in red...

journal_title：Journal of child and adolescent psychopharmacology

authors： Dorfman J,Rosen D,Pine D,Ernst M

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze changes in the prevalence and incidence of antidepressant use among children and adolescents in Finland post October, 2003. METHOD:The sample comprised all children and adolescents in Finland aged < or =19.0 years (n = 27,676) who collected one or more reimbursed prescrip...

journal_title：Journal of child and adolescent psychopharmacology

authors： Foulon V,Svala A,Koskinen H,Chen TF,Saastamoinen LK,Bell JS

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group. METHOD:Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Mayes TL,Bernstein IH,Haley CL,Kennard BD,Emslie GJ

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The use of atypical antipsychotics is increasing in adolescent populations, but little is known about adherence with these treatments. This study examined postdischarge adherence of adolescents treated as inpatients with either olanzapine or risperidone. METHODS:Eighty-six (86) adolescent inpatients (43 per...

journal_title：Journal of child and adolescent psychopharmacology

authors： Pogge DL,Singer MB,Harvey PD

更新日期：2005-12-01 00:00:00

abstract：:ABSTRACT The sudden collapse and death in three prepubertal children during routine treatment with desipramine was recently reported in brief statements. Insufficient clinical information is available to infer a cause-and-effect relationship between the therapeutic use of desipramine and sudden death in these children...

journal_title：Journal of child and adolescent psychopharmacology

authors： Popper CW,Elliott GR

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To compare fast versus slow switching from stimulants to atomoxetine (ATX) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). METHODS:This was a randomized, controlled, open-label study in 6-16-year-old ADHD patients, previously treated with stimulants and cross-titrated (fast ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cardo E,Porsdal V,Quail D,Fuentes J,Steer C,Montoya A,Anand E,Escobar R

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the 52-week safety/tolerability of oral olanzapine for adolescents with schizophrenia or bipolar mania and compare effectiveness of a standard versus intense behavioral weight intervention in mitigating risk of weight gain. METHODS:Patients 13-17 years old with schizophrenia (Brief Psychiatric R...

journal_title：Journal of child and adolescent psychopharmacology

authors： Detke HC,DelBello MP,Landry J,Hoffmann VP,Heinloth A,Dittmann RW

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the association between the CYP2D6 and CYP2C19 genotype-predicted combined phenotypes and short-term measures of psychotropic efficacy and toxicity. METHODS:A rater-blinded, retrospective genotype association design examined a cohort of hospitalized pediatric psychiatric ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Prows CA,Nick TG,Saldaña SN,Pathak S,Liu C,Zhang K,Daniels ZS,Vinks AA,Glauser TA

更新日期：2009-08-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) and related conditions including Tourette's disorder (TD) are chronic, relapsing disorders of unknown etiology associated with marked impairment and disability. Associated immune dysfunction has been reported and debated in the literature since the late 80s. The immunologic culprit ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Murphy TK,Kurlan R,Leckman J

更新日期：2010-08-01 00:00:00

abstract：:ABSTRACT The pertinent literature was reviewed on cardiovascular changes induced by psychostimulant medication treatment of hyperactive children. An assessment of 15 controlled studies using test doses of methylphenidate revealed a significant elevation of the resting heart rate in previously unmedicated children (mea...

journal_title：Journal of child and adolescent psychopharmacology

authors： Safer DJ

更新日期：1992-01-01 00:00:00

abstract：:ABSTRACT Current concerns about antidepressant efficacy in children and adolescents are reminiscent of the history of adult studies. Such awareness should temper these concerns, especially in view of the enormous progress in the last two decades of studies of adult depression. A number of methodologie, nosologie, deve...

journal_title：Journal of child and adolescent psychopharmacology

authors： Jensen PS,Ryan ND,Prien R

更新日期：1992-04-01 00:00:00

abstract：:ABSTRACT Neuroleptic malignant syndrome (NMS) is a potentially fatal disorder associated with the use of neuroleptics. Clinical research on NMS to date has focused exclusively on adults, but increasing numbers of juvenile cases have been reported. Two cases of juvenile NMS treated by the authors are discussed to demon...

journal_title：Journal of child and adolescent psychopharmacology

authors： Latz SR,McCracken JT

更新日期：1992-07-01 00:00:00

abstract：:A preliminary clinical observation suggests the possibility of changes in valproate level when coadministered with guanfacine. Two pediatric inpatients (8 and 9 years of age) were treated with valproic acid and guanfacine concurrently. In one child, when guanfacine was tapered and discontinued, the plasma valproate co...

journal_title：Journal of child and adolescent psychopharmacology

authors： Ambrosini PJ,Sheikh RM

更新日期：1998-01-01 00:00:00