Abstract:
OBJECTIVE:The aim of this study was to analyze changes in the prevalence and incidence of antidepressant use among children and adolescents in Finland post October, 2003. METHOD:The sample comprised all children and adolescents in Finland aged < or =19.0 years (n = 27,676) who collected one or more reimbursed prescriptions for an antidepressant in noninstitutional and nonhospital settings between January, 1998, and December, 2005. Time-series models were used to compare antidepressant use 60 months before and 24 months after the health advisory issued by the Food and Drug Administration (FDA) in October, 2003. RESULTS:The annual prevalence (users/1,000 youths) of antidepressant use increased from 5.24 in 2002 to 5.93 in 2005. There was an increase in the monthly incidence (users = 1,000 youths) of selective serotonin reuptake inhibitors (SSRIs) use (+0.02498), fluoxetine use (+0.00691), and sertraline use (+0.00727) post October, 2003. When considering preadvisory trends in antidepressant use, only fluoxetine use was higher than the predicted post October 2003, use (<0.001). The use of all other SSRIs was significantly lower than predicted. CONCLUSIONS:In contrast to many other countries, the use of antidepressants continued to increase among children and adolescents in Finland post October, 2003. While the rate of fluoxetine use increased, there was a decline in the rate at which all other SSRIs were used.
journal_name
J Child Adolesc Psychopharmacoljournal_title
Journal of child and adolescent psychopharmacologyauthors
Foulon V,Svala A,Koskinen H,Chen TF,Saastamoinen LK,Bell JSdoi
10.1089/cap.2009.0040subject
Has Abstractpub_date
2010-04-01 00:00:00pages
145-50issue
2eissn
1044-5463issn
1557-8992journal_volume
20pub_type
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journal_title:Journal of child and adolescent psychopharmacology
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2009-04-01 00:00:00
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更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2017-08-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Journal of child and adolescent psychopharmacology
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更新日期:1992-07-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2014-05-01 00:00:00