Abstract:
OBJECTIVE:The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group. METHOD:Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after 12 weeks of fluoxetine treatment. Global improvement was also assessed at week 12 (or exit). Reliability and validity were analyzed using Classical Test Theory (item-total correlations and internal consistency) and correlations between the CDRS-R and other outcomes. RESULTS:Adolescents (n = 145) were evaluated at screening; 113 (77.9%) met criteria for major depressive disorder, 8 (5.5%) had subthreshold depressive symptoms, and 24 (16.6%) had minimal depressive symptoms. Ninety-four adolescents had a baseline visit after 1 week, and 88 were treated with fluoxetine. Internal consistency for the CDRS-R was good at all three visits (screening: 0.79; baseline: 0.74; exit: 0.92), and total score was highly correlated with global severity (r = 0.87, 0.80, and 0.93; p < 0.01). Only exit CDRS-R score was significantly correlated with global functioning (Children's Global Assessment Scale; r = -0.77; p < 0.01). Reductions on the CDRS-R total score were highly correlated with improvement scores at exit (Clinical Global Impressions-Improvement; r = -0.83; p < 0.01). CONCLUSIONS:The results demonstrate good reliability and validity in adolescents with depression.
journal_name
J Child Adolesc Psychopharmacoljournal_title
Journal of child and adolescent psychopharmacologyauthors
Mayes TL,Bernstein IH,Haley CL,Kennard BD,Emslie GJdoi
10.1089/cap.2010.0063subject
Has Abstractpub_date
2010-12-01 00:00:00pages
513-6issue
6eissn
1044-5463issn
1557-8992journal_volume
20pub_type
杂志文章abstract::The increasing use of olanzapine for treating adolescent patients has brought with it greater awareness of the recognized side effects of this medication, especially weight gain. Of the reports of glucose dysregulation related to olanzapine therapy, only a few pertain to adolescents. We present five cases: two youths ...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/104454603321666234
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abstract:OBJECTIVE:Patterns of benzodiazepine (BZD) use and long-term use among young adults are not well known. Our aim was to study trends in BZD use and long-term use among 18-25-year-old young adults by gender and active substance in a nationwide retrospective longitudinal register-based setting. METHODS:All Finns aged 18-...
journal_title:Journal of child and adolescent psychopharmacology
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doi:10.1089/cap.2017.0140
更新日期:2018-05-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
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doi:10.1089/cap.2007.0100
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abstract:OBJECTIVE:To examine the persistence of three newly initiated stimulant preparations among Medicaid children and adolescents with attention-deficit/hyperactivity disorder (ADHD) diagnosis. METHODS:A retrospective longitudinal claims analysis was conducted by using Medicaid analytical eXtract data of four states. The s...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2011.0028
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The rate-corrected QT interval (QTc) prolongation is a risk factor for sudden cardiac death and may be induced by antipsychotic drugs. OBJECTIVE:To determine the clinical characteristics associated with QTc prolongation (440 msec or greater) in children and adolescents hospitalized for treatment of psychiat...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 临床试验,杂志文章
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更新日期:2011-08-01 00:00:00
abstract::Attention-deficit hyperactivity disorder (ADHD) and major depression are common ailments that can cause significant dysfunction throughout the life cycle. These two disorders may occur comorbidly. This case series describes 7 pediatric patients (aged 10-16 years) and 4 adults (aged 38-44 years) whose ADHD and comorbid...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.1996.6.165
更新日期:1996-10-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2017.0050
更新日期:2018-06-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1089/cap.1998.8.61
更新日期:1998-01-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
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更新日期:2014-02-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/104454602760219153
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this article was to examine whether injuries in early childhood and gender predict prescriptions of stimulant medication in three groups of children: With attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and other psychiatric disorders (OPD). METHODS:This was a ...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2013.0101
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Evening-dosed HLD200 is a delayed-release and extended-release methylphenidate (DR/ER-MPH) formulation consisting of uniform, dual-layered microbeads with an inner drug-loaded core. DR/ER-MPH is designed to delay the initial release of drug by 8-10 hours, and thereafter, provide a controlled, extended drug re...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1089/cap.2017.0084
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the preliminary effectiveness and safety of lamotrigine for the treatment of depressive episodes in adolescents. METHODS:This was a 12 week retrospective chart review of lamotrigine treatment among 37 adolescents (mean age 16.3±1.3 years) with depressive episodes ...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2013.0121
更新日期:2014-06-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2004.14.582
更新日期:2004-01-01 00:00:00
abstract::Treatment with psychostimulant medication has been shown to improve scholastic functioning in children with attention-deficit/hyperactivity disorder (ADHD). However, the extent to which long-term academic gains are apparent in those having received such treatment remains elusive. This study examined prospectively the ...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2008.021
更新日期:2008-10-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1089/cap.2009.0059
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to describe the special considerations for building rapport and establishing a therapeutic alliance when conducting mental health evaluations for children and adolescents via videoconferencing. METHODS:The authors review the literature and describe their experience in conducting...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2015.0022
更新日期:2016-04-01 00:00:00
abstract:: Objective: To guide clinicians in selecting the "next line" selective serotonin reuptake inhibitor (SSRI) for adolescents with treatment-resistant major depressive disorder, we sought to compare response rates among SSRIs in the Treatment of SSRI-Resistant Depression in Ad...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2018.0145
更新日期:2019-05-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2014-05-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
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更新日期:1992-10-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2009.0105
更新日期:2010-10-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1089/cap.2016.0123
更新日期:2017-04-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章,评审
doi:10.1089/cap.2012.0093
更新日期:2013-04-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.1999.9.169
更新日期:1999-01-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2016.0182
更新日期:2017-06-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/cap.2000.10.295
更新日期:2000-01-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2005.15.693
更新日期:2005-08-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2006.16.456
更新日期:2006-08-01 00:00:00
abstract::Obsessive-compulsive disorder (OCD) and related conditions including Tourette's disorder (TD) are chronic, relapsing disorders of unknown etiology associated with marked impairment and disability. Associated immune dysfunction has been reported and debated in the literature since the late 80s. The immunologic culprit ...
journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章,评审
doi:10.1089/cap.2010.0043
更新日期:2010-08-01 00:00:00
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journal_title:Journal of child and adolescent psychopharmacology
pub_type: 杂志文章
doi:10.1089/cap.2014.0055
更新日期:2014-11-01 00:00:00