Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.

abstract：BACKGROUND:Bacteria belonging to the Rhodococcus genus play an important role in the degradation of many contaminants, including methylbenzenes. These bacteria, widely distributed in the environment, are known to be a powerhouse of numerous degradation functions, due to their ability to metabolize a wide range of organ...

journal_title：BMC genomics

authors： Di Canito A,Zampolli J,Orro A,D'Ursi P,Milanesi L,Sello G,Steinbüchel A,Di Gennaro P

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:Understanding syntentic relationship between two species is critical to assessing the potential for comparative genomic analysis. Common bean (Phaseolus vulgaris L.) and soybean (Glycine max L.), the two most important members of the Phaseoleae legumes, appear to have a diploid and polyploidy recent past, re...

journal_title：BMC genomics

authors： McClean PE,Mamidi S,McConnell M,Chikara S,Lee R

更新日期：2010-03-18 00:00:00

abstract：BACKGROUND:In the model legume Medicago truncatula, the near saturation genome-wide Tnt1 insertion mutant population in ecotype R108 is a valuable tool in functional genomics studies. Forward genetic screens have identified many Tnt1 mutants defective in nodule development and symbiotic nitrogen fixation (SNF). However...

journal_title：BMC genomics

authors： Veerappan V,Jani M,Kadel K,Troiani T,Gale R,Mayes T,Shulaev E,Wen J,Mysore KS,Azad RK,Dickstein R

更新日期：2016-02-27 00:00:00

abstract：BACKGROUND:Transposable elements are selfish genetic sequences which only occasionally provide useful functions to their host species. In addition, models of mobile element evolution assume a second type of selfishness: elements of different families do not cooperate, but they independently fight for their survival in ...

journal_title：BMC genomics

authors： Marco A,Marín I

更新日期：2008-05-14 00:00:00

abstract：BACKGROUND:Exosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in cell-cell communication. These RNA transcripts have great potential as disease biomarkers. To characterize exosomal RNA profiles systemically, we performed RNA sequencing analysis using thre...

journal_title：BMC genomics

authors： Huang X,Yuan T,Tschannen M,Sun Z,Jacob H,Du M,Liang M,Dittmar RL,Liu Y,Liang M,Kohli M,Thibodeau SN,Boardman L,Wang L

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:Initial interest in Dechloromonas aromatica strain RCB arose from its ability to anaerobically degrade benzene. It is also able to reduce perchlorate and oxidize chlorobenzoate, toluene, and xylene, creating interest in using this organism for bioremediation. Little physiological data has been published for ...

journal_title：BMC genomics

authors： Salinero KK,Keller K,Feil WS,Feil H,Trong S,Di Bartolo G,Lapidus A

更新日期：2009-08-03 00:00:00

abstract：BACKGROUND:Yellow-feathered chickens (YFCs) have a long history in China. They are well-known for the nutritional and commercial importance attributable to their yellow color phenotype. Currently, there is a huge paucity in knowledge of the genetic determinants responsible for phenotypic and biochemical properties of t...

journal_title：BMC genomics

authors： Huang X,Otecko NO,Peng M,Weng Z,Li W,Chen J,Zhong M,Zhong F,Jin S,Geng Z,Luo W,He D,Ma C,Han J,Ommeh SC,Zhang Y,Zhang X,Du B

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Species of the crenarchaeon Sulfolobus harbour three replication origins in their single circular chromosome that are synchronously initiated during replication. RESULTS:We demonstrate that global gene expression in two Sulfolobus species is highly biased, such that early replicating genome regions are more...

journal_title：BMC genomics

authors： Andersson AF,Pelve EA,Lindeberg S,Lundgren M,Nilsson P,Bernander R

更新日期：2010-07-28 00:00:00

abstract：BACKGROUND:gammadelta T cells differ from alphabeta T cells with regard to the types of antigen with which their T cell receptors interact; gammadelta T cell antigens are not necessarily peptides nor are they presented on MHC. Cattle are considered a "gammadelta T cell high" species indicating they have an increased pr...

journal_title：BMC genomics

authors： Herzig CT,Lefranc MP,Baldwin CL

更新日期：2010-02-09 00:00:00

abstract：BACKGROUND:Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the presence of specific T-cell epitopes (9-mer peptides; CD epitopes) that mediate the stimulation of HL...

journal_title：BMC genomics

authors： Salentijn EM,Mitea DC,Goryunova SV,van der Meer IM,Padioleau I,Gilissen LJ,Koning F,Smulders MJ

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:The term pan-genome was proposed to denominate collections of genomic sequences jointly analyzed or used as a reference. The constant growth of genomic data intensifies development of data structures and algorithms to investigate pan-genomes efficiently. RESULTS:This work focuses on providing a tool for dis...

journal_title：BMC genomics

authors： Dziadkiewicz P,Dojer N

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Intergenic splicing resulting in the combination of mRNAs sequences from distinct genes is a newly identified mechanism likely to contribute to protein diversity. Few cases have been described, most of them involving neighboring genes and thus suggesting a cotranscription event presumably due to transcriptio...

journal_title：BMC genomics

authors： Roux M,Levéziel H,Amarger V

更新日期：2006-04-04 00:00:00

abstract：BACKGROUND:Transposable elements (TEs) are mobile genetic sequences that randomly propagate within their host's genome. This mobility has the potential to affect gene transcription and cause disease. However, TEs are technically challenging to identify, which complicates efforts to assess the impact of TE insertions on...

journal_title：BMC genomics

authors： Kvikstad EM,Piazza P,Taylor JC,Lunter G

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Bixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L. An enzymatic pathway for bixin biosynthesis was inferred from homology of putative proteins encoded by differentially expressed seed cDNAs. Some activities we...

journal_title：BMC genomics

authors： Cárdenas-Conejo Y,Carballo-Uicab V,Lieberman M,Aguilar-Espinosa M,Comai L,Rivera-Madrid R

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Maintaining maximum genetic diversity and preserving breed viability in conserved populations necessitates the rigorous evaluation of conservation schemes. Three chicken breeds (Baier Yellow Chicken (BEC), Beijing You Chicken (BYC) and Langshan Chicken (LSC)) are currently in conservation programs in China. ...

journal_title：BMC genomics

authors： Zhang M,Han W,Tang H,Li G,Zhang M,Xu R,Liu Y,Yang T,Li W,Zou J,Wu K

更新日期：2018-08-09 00:00:00

abstract：BACKGROUND:Spinal cord injury leads to neurological dysfunctions affecting the motor, sensory as well as the autonomic systems. Increased excitability of motor neurons has been implicated in injury-induced spasticity, where the reappearance of self-sustained plateau potentials in the absence of modulatory inputs from t...

journal_title：BMC genomics

authors： Ryge J,Winther O,Wienecke J,Sandelin A,Westerdahl AC,Hultborn H,Kiehn O

更新日期：2010-06-09 00:00:00

abstract：BACKGROUND:During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of genes in a genome. Our aim is to compute the evolutionary distance b...

journal_title：BMC genomics

authors： Cordonnier G,Lafond M

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:The hard clam or northern quahog, Mercenaria mercenaria, is one of the most valuable seafood products in the United States representing the first marine resource in some Northeastern states. Severe episodes of hard clam mortality have been consistently associated with infections caused by a thraustochytrid p...

journal_title：BMC genomics

authors： Rubin E,Tanguy A,Perrigault M,Pales Espinosa E,Allam B

更新日期：2014-03-28 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNAs that regulate genes at the post-transcriptional level in spatiotemporal manner. Several miRNAs are identified as prognostic and diagnostic markers in many human cancers. Estimation of the temporal activities of the miRNAs is an important step in the way to underst...

journal_title：BMC genomics

authors： Jayavelu ND,Bar N

更新日期：2015-12-18 00:00:00

abstract：BACKGROUND:Exiguobacterium antarcticum strain B7 is a Gram-positive psychrotrophic bacterial species isolated in Antarctica. Although this bacteria has been poorly studied, its genome has already been sequenced. Therefore, it is an appropriate model for the study of thermal adaptation. In the present study, we analyzed...

journal_title：BMC genomics

authors： Dall'Agnol HP,Baraúna RA,de Sá PH,Ramos RT,Nóbrega F,Nunes CI,das Graças DA,Carneiro AR,Santos DM,Pimenta AM,Carepo MS,Azevedo V,Pellizari VH,Schneider MP,Silva A

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Pectobacterium spp. are necrotrophic bacterial plant pathogens of the family Pectobacteriaceae, responsible for a wide spectrum of diseases of important crops and ornamental plants including soft rot, blackleg, and stem wilt. P. carotovorum is a genetically heterogeneous species consisting of three valid sub...

journal_title：BMC genomics

authors： Li X,Ma Y,Liang S,Tian Y,Yin S,Xie S,Xie H

更新日期：2018-12-07 00:00:00

abstract：MOTIVATION:Deciphering gene interaction networks (GINs) from time-course gene expression (TCGx) data is highly valuable to understand gene behaviors (e.g., activation, inhibition, time-lagged causality) at the system level. Existing methods usually use a global or local proximity measure to infer GINs from a single dat...

journal_title：BMC genomics

authors： Liu Q,Song R,Li J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The process of alternative splicing provides a unique mechanism by which eukaryotes are able to produce numerous protein products from the same gene. Heightened variability in the proteome has been thought to potentiate increased behavioral complexity and response flexibility to environmental stimuli, thus c...

journal_title：BMC genomics

authors： Lang AS,Austin SH,Harris RM,Calisi RM,MacManes MD

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Oxidative stress is a consequence of normal and abnormal cellular metabolism and is linked to the development of human diseases. The effective functioning of the pathway responding to oxidative stress protects the cellular DNA against oxidative damage; conversely the failure of the oxidative stress response ...

journal_title：BMC genomics

authors： Sridharan S,Layek R,Datta A,Venkatraj J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Despite recent work to characterize gene expression changes associated with larval development in oysters, the mechanism by which the larval shell is first formed is still largely unknown. In Crassostrea gigas, this shell forms within the first 24 h post fertilization, and it has been demonstrated that chang...

journal_title：BMC genomics

authors： De Wit P,Durland E,Ventura A,Langdon CJ

更新日期：2018-02-22 00:00:00

abstract：BACKGROUND:Missing data is an inevitable phenomenon in gene expression microarray experiments due to instrument failure or human error. It has a negative impact on performance of downstream analysis. Technically, most existing approaches suffer from this prevalent problem. Imputation is one of the frequently used metho...

journal_title：BMC genomics

authors： Li H,Zhao C,Shao F,Li GZ,Wang X

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Lysophosphatidic acid acyltransferase (LPAAT) encoded by a multigene family is a rate-limiting enzyme in the Kennedy pathway in higher plants. Cotton is the most important natural fiber crop and one of the most important oilseed crops. However, little is known on genes coding for LPAATs involved in oil biosy...

journal_title：BMC genomics

authors： Wang N,Ma J,Pei W,Wu M,Li H,Li X,Yu S,Zhang J,Yu J

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Monotonic Feature Selector (MFSelector) based on a concept of total discriminating error (DEtotal) to i...

journal_title：BMC genomics

authors： Wang HW,Sun HJ,Chang TY,Lo HH,Cheng WC,Tseng GC,Lin CT,Chang SJ,Pal N,Chung IF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Fasting induces specific molecular and metabolic adaptions in most organisms. In biomedical research fasting is used in metabolic studies to synchronize nutritional states of study subjects. Because there is a lack of standardization for this procedure, we need a deeper understanding of the dynamics and the ...

journal_title：BMC genomics

authors： Schupp M,Chen F,Briggs ER,Rao S,Pelzmann HJ,Pessentheiner AR,Bogner-Strauss JG,Lazar MA,Baldwin D,Prokesch A

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders such as the Williams-B...

journal_title：BMC genomics

authors： Ebert G,Steininger A,Weißmann R,Boldt V,Lind-Thomsen A,Grune J,Badelt S,Heßler M,Peiser M,Hitzler M,Jensen LR,Müller I,Hu H,Arndt PF,Kuss AW,Tebel K,Ullmann R

更新日期：2014-06-29 00:00:00