Abstract:
:Ribonuclease P (RNase P) is a ribonucleoprotein comprised of a catalytic RNA subunit and one or several protein subunits. RNase P is best known for its role in 5'-processing of tRNA precursors. RNase P enzymes from almost all forms of life, including protein-synthesizing organelles, contain an RNase P with a conserved, homologous RNA. Five distinct structure classes of RNase P RNAs have been identified in bacteria and archaea; eukaryotic RNase P RNAs are not yet sufficiently well surveyed for structure classes to be defined. Here we will examine the structure variations in RNase P RNAs in bacteria, archaea, eukaryotes, plastids and mitochondria with special emphasis on the functional roles these unique secondary structures perform.
journal_name
RNA Bioljournal_title
RNA biologyauthors
Ellis JC,Brown JWdoi
10.4161/rna.6.4.9241subject
Has Abstractpub_date
2009-09-01 00:00:00pages
362-9issue
4eissn
1547-6286issn
1555-8584pii
9241journal_volume
6pub_type
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