Abstract：
:This study examined the neural basis of auditory selective attention using functional magnetic resonance imaging. The main hypothesis stated that attending to a particular sound frequency would significantly enhance the neural response within those tonotopic regions of the auditory cortex sensitive to that frequency. To test this prediction, low- and high-frequency sound sequences were interleaved to produce two concurrent auditory streams. Six normally hearing participants either performed a task which required them to attend to one or the other stream or listened passively to the sounds while functional images were acquired using a high-resolution (1.5 mm x 1.5 mm x 2.5 mm) sequence. Two statistical comparisons identified the attention-specific and general effects of enhancement. The first controlled for task-related processes, while the second did not. Results demonstrated frequency-specific, attention-specific enhancement in the response to the attended frequency, but no response suppression for the unattended frequency. Instead, a general effect of suppression was found in several posterior sites, possibly related to resting-state processes. Furthermore, there was widespread general enhancement across auditory cortex when performing the task compared to passive listening. This enhancement did include frequency-sensitive regions, but was not restricted to them. In conclusion, our results show partial support for frequency-specific enhancement.
journal_name
Hear Resjournal_title
Hearing researchauthors
Paltoglou AE,Sumner CJ,Hall DAdoi
10.1016/j.heares.2009.08.007subject
Has Abstractpub_date
2009-11-01 00:00:00pages
106-18issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(09)00201-9journal_volume
257pub_type
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