Serum and pleural fluid procalcitonin in predicting bacterial infection in patients with parapneumonic effusion.

Abstract:

:This study evaluated the value of procalcitonin (PCT) levels in pleural effusion to differentiate the etiology of parapneumonic effusion (PPE). Forty-one consecutive PPE patients were enrolled and were divided into bacterial and non-bacterial PPE. Blood and pleural effusion samples were collected for PCT measurement on admission and analyzed for diagnostic evaluation. PCT of pleural fluid was significantly increased in the bacterial PPE group (0.24 ng/mL) compared to the non-bacterial PPE group (0.09 ng/mL), but there was no significant difference for serum PCT. A PCT concentration of pleural fluid >0.174 ng/mL (best cut-off value) was considered positive for a diagnosis of bacterial PPE (sensitivity, 80%; specificity, 76%; AUC, 0.84). Pleural effusion PCT in the bacterial PPE is significantly different from those of the non-bacterial PPE and control groups, so the diagnostic use of PCT still warrants further investigation.

journal_name

J Korean Med Sci

authors

Ko YC,Wu WP,Hsu CS,Dai MP,Ou CC,Kao CH

doi

10.3346/jkms.2009.24.3.398

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

398-402

issue

3

eissn

1011-8934

issn

1598-6357

journal_volume

24

pub_type

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