Lung volume reduction surgery for the management of refractory dyspnea in chronic obstructive pulmonary disease.

abstract：PURPOSE OF REVIEW:To understand the mechanisms of muscle wasting and how inhibiting myostatin signaling affects them. RECENT FINDINGS:Myostatin signaling is critical for the understanding of the pathogenesis of muscle wasting as blocking signaling mitigates muscle losses in rodent models of catabolic diseases includin...

journal_title：Current opinion in supportive and palliative care

authors： Han HQ,Mitch WE

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite a limited understanding of the exact mechanism, corticosteroids are commonly employed for pain control in patients with bone metastases. The aim of this review was to evaluate the efficacy of corticosteroid-mediated pain control in patients with bone metastases associated with solid cancers. ...

journal_title：Current opinion in supportive and palliative care

authors： Lim FMY,Bobrowski A,Agarwal A,Silva MF

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This mixed-method, rapid review of published research from 2014 to 2019 aims to explore the experiences of pre and postbereaved carers, and the information that they receive in the acute hospital setting. The quality of articles was evaluated using a standardized quality matrix. The techniques of conc...

journal_title：Current opinion in supportive and palliative care

authors： Jackson B,McPeake J,Johnston B

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the status of guidelines and recommendations for communication between patients with cancer and healthcare providers (HCPs) concerning fertility issues. RECENT FINDINGS:The timing, the type of information provided, and the openness of HCPs can all affect how patients with cancer ...

journal_title：Current opinion in supportive and palliative care

authors： Shen S,Zelkowitz P,Rosberger Z

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The review is based on a Medline literature search using key words relating to male urogenital/pelvic pain for the years 2009-2011. RECENT FINDINGS:The review covers those studies relating to cause, ongoing mechanisms and treatments. SUMMARY:The review highlights that the patients are often polysymp...

journal_title：Current opinion in supportive and palliative care

authors： Baranowski AP

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:International bodies acknowledge that palliative care principles and access to palliative care services should be offered to persons living with and dying from advanced illness such as heart failure. Without an appropriately trained workforce, however, appropriate goals of care and associated reductio...

journal_title：Current opinion in supportive and palliative care

authors： Millerick Y,Armstrong I

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Determining which palliative interventions are appropriate within and between groups remains difficult because of the lack of prospective studies and heterogeneity in dyspnoea context, assessment and reporting. This review presents an evolution of dyspnoea theories, summarizes literature published dur...

journal_title：Current opinion in supportive and palliative care

authors： Williams M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients' autonomy is seen as a major issue in modern medicine but requires the ability to understand and rate an issue without being influenced by others. However, near the end of life, patients often decide considering the consequences for their relatives. RECENT FINDINGS:Our study results and rece...

journal_title：Current opinion in supportive and palliative care

authors： Marx G,Owusu Boakye S,Jung A,Nauck F

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Right-sided heart failure, which is often present in the setting of advanced heart failure, is associated with cardiac cachexia, the cardiorenal syndrome, and adverse outcomes. Improved understanding of venous congestion of the splanchnic circulation, which may play a key role in the pathogenesis of r...

journal_title：Current opinion in supportive and palliative care

authors： Polsinelli VB,Marteau L,Shah SJ

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Overall survival of patients with pancreatic cancer is strongly conditioned by tumor biology and the incidence of malnutrition and metabolic disorders. In this landscape, the assessment of body composition is crucial to properly manage the clinical implications of muscle wasting. The pathogenesis of t...

journal_title：Current opinion in supportive and palliative care

authors： Basile D,Corvaja C,Caccialanza R,Aprile G

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteoarthritis is a complex and often painful disease that is inadequately controlled with current analgesics. This review discusses emerging targets and therapeutic approaches that may lead to the development of better analgesics. RECENT FINDINGS:Aberrant excitability in peripheral and central pain ...

journal_title：Current opinion in supportive and palliative care

authors： Rahman W,Dickenson AH

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Care near the end of life is expensive and frequently not aligned with the expressed preferences of decedents, creating an opportunity to improve value, or increase quality while lowering cost. This review examines publications from 2017 and 2018 on interventions and policies associated with high-valu...

journal_title：Current opinion in supportive and palliative care

authors： Ankuda CK,Meier DE

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF THE REVIEW:The purpose of review is to critically present the evidence supporting the use of olanzapine, an atypical antipsychotic, as an antiemetic for cancer and chemotherapy-induced nausea and vomiting (CINV). RECENT FINDINGS:Two phase III clinical studies demonstrated superior efficacy of olanzapine in ...

journal_title：Current opinion in supportive and palliative care

authors： Bosnjak SM,Dimitrijevic J,Djordjevic F

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Agents used for systemic chemotherapy can alter normal bone homeostasis through mechanisms that affect both osteoblast and osteoclast function. The identification of those agents that influence maintenance of the bone-remodeling compartment is an important component of the drug development and testing...

journal_title：Current opinion in supportive and palliative care

authors： Silbermann R,Roodman GD

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on chemotherapy in the management of patients with advanced urothelial cancer, with a look towards the future and the next generation of clinical trials. RECENT FINDINGS:The recognition that the maximum benefit from conventional combination chemotherapy has been achieved has led t...

journal_title：Current opinion in supportive and palliative care

authors： Calabrò F,Sternberg CN

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Effective communication in cancer care requires complex communication skills of healthcare professionals (HCPs), which can be advanced by communication skills training (CST). The number of empirical studies on CST has grown steadily over the last decade. However, controversies on CST abound. The aim o...

journal_title：Current opinion in supportive and palliative care

authors： Bos-van den Hoek DW,Visser LNC,Brown RF,Smets EMA,Henselmans I

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Good communication is the cornerstone of interprofessional care teams providing optimized quality patient care. Over the last decade, advances in technology have provided tools to improve communication; however, opportunities still exist for innovation and implementation. RECENT FINDINGS:The literatu...

journal_title：Current opinion in supportive and palliative care

authors： D'Alimonte L,McLaney E,Di Prospero L

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:RANK ligand (RANKL) plays a central role in the cancer-induced bone destruction that results from bone metastasis. The RANKL inhibitor denosumab was recently approved for the prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumors. This review summarizes recent ...

journal_title：Current opinion in supportive and palliative care

authors： Lipton A,Jacobs I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the palliative management of gastrointestinal symptoms experienced by advanced cancer patients and provides a framework for detailing that encompasses education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment opti...

journal_title：Current opinion in supportive and palliative care

authors： Abernethy AP,Wheeler JL,Zafar SY

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:It is difficult to hold an organized view of psychological research related to chronic pain. There are many different theories and variables and the volume of literature is vast. The purpose of this review is to highlight some key trends in this research in 2010. RECENT FINDINGS:We conducted a search...

journal_title：Current opinion in supportive and palliative care

authors： McCracken LM,Thompson M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Sequential anthracycline/taxane regimens are routinely used as neoadjuvant therapy (NAT) for locally advanced breast cancer. Unfortunately, the majority of patients do not achieve a pathological complete response (pCR). Efforts to improve pCR rates include the addition of novel targeted agents. The pu...

journal_title：Current opinion in supportive and palliative care

authors： Wilson S,Chia S

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiation therapy-induced nausea and vomiting (RINV) are common and troublesome symptoms among patients receiving radiation therapy for gastrointestinal cancers. Their impact on function, quality of life and, ultimately, cancer control warrant a review of their incidence, underlying mechanisms, treatm...

journal_title：Current opinion in supportive and palliative care

authors： Dennis K,Poon M,Chow E

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize current knowledge on promising immunotherapeutic agents and to provide a brief outline of current use of immunotherapeutic agents in patients with locally advanced or metastatic renal cell carcinoma (RCC). RECENT FINDINGS:Immunotherapy with mAbs directed against programed death cell prot...

journal_title：Current opinion in supportive and palliative care

authors： Nazzani S,Bazinet A,Karakiewicz PI

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The palliative care needs of people with interstitial lung disease (ILD) have recently been highlighted by the National Institute for Health and Care Excellence. All people with progressive ILD should receive best supportive care to improve symptom control and quality of life and where possible this s...

journal_title：Current opinion in supportive and palliative care

authors： Bajwah S,Yorke J

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:There are increasing numbers of adults with congenital heart disease (CHD) and these patients remain at long-term risk of complications and premature death. This review focuses on the changing picture of adult CHD with more complex patients surviving, the challenges of balancing life-prolonging interv...

journal_title：Current opinion in supportive and palliative care

authors： Bowater SE,Speakman JK,Thorne SA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article describes the role of the PD-1 axis and reviews current data and future directions inhibiting PD-1 and PD-L1 in breast cancer. RECENT FINDINGS:Four phase I monotherapy expansion trials in patients with metastatic breast cancer have demonstrated low but durable single agent responses to P...

journal_title：Current opinion in supportive and palliative care

authors： Dawood S,Rugo HS

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. RECENT FINDINGS:This review discusses the process required to conduct trials of ...

journal_title：Current opinion in supportive and palliative care

authors： Davis MP,Mitchell GK

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cancer cachexia remains understudied and there are no standard treatments available despite the publication of an international consensus definition and the completion of several large phase III intervention trials in the past 6 years. In September 2015, The University of Rochester Cancer Center NCORP...

journal_title：Current opinion in supportive and palliative care

authors： Dunne RF,Mustian KM,Garcia JM,Dale W,Hayward R,Roussel B,Buschmann MM,Caan BJ,Cole CL,Fleming FJ,Chakkalakal JV,Linehan DC,Hezel AF,Mohile SG

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the psychosocial support of people affected by cancer anorexia, drawing on recent publications. RECENT FINDINGS:Recent studies describe the problem of distress in response to cancer anorexia. There are propositions of appropriate support and calls for the development of psychosocial interv...

journal_title：Current opinion in supportive and palliative care

authors： Hopkinson JB

更新日期：2010-12-01 00:00:00