Polymorphism of CYP1A1*2C, GSTM1*0, and GSTT1*0 in a Mexican Mestizo population: a similitude analysis.

abstract：:Involvement of genetic factors in determining bone mineral density (BMD) is doubtless. However, the exact nature of the genes governing BMD variation and sources for genetic determination of BMD of different parts of bone (compact and cancellous) have not been completely studied. The results of the complex segregation...

journal_title：Human biology

authors： Livshits G,Karasik D,Pavlovsky O,Kobyliansky E

更新日期：1999-04-01 00:00:00

abstract：:It is generally accepted that the relationship between human genes and language is very complex and multifaceted. This has its roots in the “regular” complexity governing the interplay among genes and between genes and environment for most phenotypes, but with the added layer of supraontogenetic and supra-individual p...

journal_title：Human biology

authors： Dediu D

更新日期：2011-04-01 00:00:00

abstract：:Relatives may tend to die of the same cause. A model is proposed specifying the degree of this association, simultaneously allowing for misclassification of cause of death. These mistakes usually degrade any existing correlation structure, the effects being marked when error rates reach between 20% to 30%. It is then ...

journal_title：Human biology

authors： Tallis GM

更新日期：2002-02-01 00:00:00

abstract：:We analyze the possible effect of gene flow on the genetic structure of present-day Mexicans. For this purpose we reviewed previous admixture estimates for various Indian and Mestizo groups. Several facts seem clear: (1) There are no pure Indian groups in Mexico, because all Indian groups show variable degrees of admi...

journal_title：Human biology

authors： Lisker R,Ramírez E,Babinsky V

更新日期：1996-06-01 00:00:00

abstract：:The present study reports the genetic variation observed among five anthropologically distinct population groups of India, using four highly polymorphic minisatellite loci (D1S80, D17S5, D19S20, and APOB 3' VNTR) in order to examine the effect of geographical and linguistic affiliations on the genetic affinities among...

journal_title：Human biology

authors： Das B,Ghosh A,Chauhan PS,Seshadri M

更新日期：2002-06-01 00:00:00

abstract：:The main goal of the present study is to elucidate the extent to which primary characteristics of bone aging are determined by major gene effects. We report the results of a complex segregation analysis of bone mineral density (BMD) and osseographic score (OS) carried out on an array of pedigrees from rural Turkmenia....

journal_title：Human biology

authors： Livshits G,Pavlovsky O,Kobyliansky E

更新日期：1996-08-01 00:00:00

abstract：:Mutations in the GJB2 gene are a major cause of congenital deafness. One specific mutation, the 35delG mutation, has accounted for most of the GJB2 mutations detected in European populations and is one of the most frequent disease mutations identified so far. We evaluated the frequency of the 35delG mutation in DNA sa...

journal_title：Human biology

authors： Oliveira CA,Alexandrino F,Abe-Sandes K,Silva WA Jr,Maciel-Guerra AT,Magna LA,Sartorato EL

更新日期：2004-04-01 00:00:00

abstract：:The 657del5 mutation of the NBS1 gene has been demonstrated in most patients with Nijmegen breakage syndrome (NBS). We identified four Turkish families in which probands were diagnosed as having NBS and found to be homozygous for the 657del5 mutation. The 657del5 allele in the four Turkish families had a single origin...

journal_title：Human biology

authors： Tekin M,Akcayoz D,Ucar C,Gulen H,Akar N

更新日期：2005-06-01 00:00:00

abstract：:A random sample of death records of adult males from the period 1967 to 1970 was chosen from the South Australian Registry of Births, Deaths, and Marriages. The natural parents of these individuals were identified by cross-referencing to birth certificates, and an extensive search was made of the death records for the...

journal_title：Human biology

authors： Tallis GM,Leppard P

更新日期：1997-12-01 00:00:00

abstract：:In one of the truly classic works in anthropological genetics, Frank Livingstone established the interrelationships between agriculture, mosquito ecology, malaria, and, consequently, the frequencies of sickle cell hemoglobin in West Africa. A major inference from Livingstone's study was the recency of malaria as a sel...

journal_title：Human biology

authors： Fix AG

更新日期：2003-08-01 00:00:00

abstract：:The blood glucose levels of pregnant women with insulin-dependent diabetes mellitus and the blood glucose levels of newborns during the first few hours of life show an association with maternal Rh genotype. Distortions of joint maternal-fetal Rh phenotype distribution have also been observed. Because a cluster of gene...

journal_title：Human biology

authors： Gloria-Bottini F,Gerlini G,Amante A,Pascone R,Bottini E

更新日期：1992-02-01 00:00:00

abstract：:While discriminant function analysis is an inherently Bayesian method, researchers attempting to estimate ancestry in human skeletal samples often follow discriminant function analysis with the calculation of frequentist-based typicalities for assigning group membership. Such an approach is problematic because it fail...

journal_title：Human biology

authors： Konigsberg LW,Frankenberg SR

更新日期：2018-01-01 00:00:00

abstract：:The primary purpose of this research is to collate, compare, and discuss the presently available data for head and face dimensions among Korean and Japanese ethnic groups. Classification of Korean male and female head and face types is simpler than classification of Japanese subjects. Male groups have more statistical...

journal_title：Human biology

authors： Lee HJ,Park SJ

更新日期：2008-06-01 00:00:00

abstract：:A central problem in research on twins is the estimation of the rates of monozygotic and dizygotic twin maternities. The estimation usually follows Weinberg's differential rule. According to this rule, the rate of dizygotic twinning is twice the rate of twin maternities in which the twins are of opposite sex. The mono...

journal_title：Human biology

authors： Fellman J,Eriksson AW

更新日期：2006-06-01 00:00:00

abstract：:Genetic diversity among ethnic groups is studied by comparing the genetic fingerprint of the examined groups. This index is constructed by aggregating the differential frequencies of various marker characteristics. Recent advances in the study of human biological rhythms may provide new indexes that will complement th...

journal_title：Human biology

authors： Ticher A,Zoossmann-Diskin A,Haus E,Sackett-Lundeen L,Ashkenazi IE

更新日期：1995-10-01 00:00:00

abstract：:Several studies have shown evidence of an association between the *4 allele of apolipoprotein E (APOE) and coronary heart disease (CHD) in different populations. We determined the APOE genotype and total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDLC) values in 189 patients with a...

journal_title：Human biology

authors： Bañares VG,Peterson G,Aguilar D,Gulayin R,Sisu E,Wyszynski DF,Pivetta OH,Tavella MJ

更新日期：2005-04-01 00:00:00

abstract：:HLA-DQB1*0302 allele frequency is increased in liver graft recipients with acute rejection. We investigated polymorphism in the upstream regulatory regions (URRs) of the DQB1 gene to determine whether polymorphism in the DQB1 promoter region influences liver graft acceptance. A combination of typing protocols based on...

journal_title：Human biology

authors： Muro M,Herrero N,Marin L,Torío A,Minguela A,Sánchez-Bueno F,García-Alonso AM,Alvarez-López MR

更新日期：2001-12-01 00:00:00

abstract：:Models that examine genetic differences between populations alongside a genotype-phenotype map can provide insight about phenotypic variation among groups. We generalize a simple model of a completely heritable, additive, selectively neutral quantitative trait to examine the relationship between single-locus genetic d...

journal_title：Human biology

authors： Edge MD,Rosenberg NA

更新日期：2015-10-01 00:00:00

abstract：:Anthropoid phylogeny has been characterized by dramatic increases in relative brain size. Given the importance of genetic mechanisms in evolution, quantitative genetic analyses of the biological concomitants of relative brain size variation should greatly augment our understanding of this phylogenetic phenomenon. In h...

journal_title：Human biology

authors： Mahaney MC,Williams-Blangero S,Blangero J,Leland MM

更新日期：1993-12-01 00:00:00

abstract：:This article examines the utility of the ischium-pubic index (IPI), a sexing technique that compares the lengths of pubis and ischium. The ratio was adapted by Washburn from a primate index devised by Schultz and was tested by Washburn on documented remains from the Hamann-Todd Human Osteological Collection. The IPI i...

journal_title：Human biology

authors： Drew R

更新日期：2013-08-01 00:00:00

abstract：:When sampling locations are known, the association between genetic and geographic distances can be tested by spatial autocorrelation or regression methods. These tests give some clues to the possible shape of the genetic landscape. Nevertheless, correlation analyses fail when attempting to identify where genetic barri...

journal_title：Human biology

authors： Manni F,Guérard E,Heyer E

更新日期：2004-04-01 00:00:00

abstract：:Recent cloning of RH genes has elucidated their structure, suggesting that RH proteins are part of an oligomeric complex with transport function in the erythrocyte. This observation prompted us to investigate a possible relationship between the RH system and the glycosylated hemoglobin level (Hb A(1c)) in diabetes. Th...

journal_title：Human biology

authors： Gloria-Bottini F,Antonacci E,Bottini N,Ogana A,Borgiani P,De Santis G,Lucarini N

更新日期：2000-04-01 00:00:00

abstract：:The method of isonymy, developed by Crow and Mange for estimating inbreeding from surname frequencies, requires an assumption that has not been appreciated: It is necessary to assume that all males in some ancestral generation, the founding stock, had unique surnames. Because this assumption is seldom justified in rea...

journal_title：Human biology

authors： Rogers AR

更新日期：1991-10-01 00:00:00

abstract：:Recent studies have expanded and refined the founding haplogroups of the Americas using whole mitochondrial (mtDNA) genome analysis. In addition to pan-American lineages, specific variants have been identified in a number of studies that show higher frequencies in restricted geographical areas. To further characterize...

journal_title：Human biology

authors： Lee EJ,Merriwether DA

更新日期：2015-01-01 00:00:00

abstract：:The knowledge of a population structure may constitute a powerful tool for mapping genes underlying susceptibility to Mendelian and complex diseases. To obtain a better understanding of the population structure of São Miguel Island (Azorean Archipelago, Portugal), we carried out a surname survey using the surnames lis...

journal_title：Human biology

authors： Branco CC,Mota-Vieira L

更新日期：2003-12-01 00:00:00

abstract：:The use of ancient DNA techniques in human studies has been hampered by problems of contamination with modern human DNA. The main problem has been that the object of study belongs to the same species as the observer, and the complete elimination of the contamination risk is seemingly unlikely. Contamination has even b...

journal_title：Human biology

authors： Montiel R,Malgosa A,Francalacci P

更新日期：2001-10-01 00:00:00

abstract：:The polymorphism of human mitochondrial DNA (mtDNA) was studied in 118 unrelated Greeks (from northern Greece) using total blood cell DNA and the restriction enzymes HpaI, BamHI, HaeII, MspI, AvaII, and HincII. One new morph was identified for MspI (named MspI morph 18Gr) and is the result of a mutation in a previousl...

journal_title：Human biology

authors： Astrinidis A,Kouvatsi A

更新日期：1994-08-01 00:00:00

abstract：:Cross-cultural studies of sex-specific mortality indicate that, whereas males experience their greatest mortality in industrialized societies, females experience their greatest mortality in populations with low life expectancy. The higher mortality of females in low-life-expectancy communities has been interpreted as ...

journal_title：Human biology

authors： Madrigal L

更新日期：1992-04-01 00:00:00

abstract：:The relation between TaqI restriction fragment length polymorphisms (RFLPs) of the cholesteryl ester transfer protein (CETP) gene and plasma lipid and lipoprotein phenotypes was investigated in a sample of Italian and Greek migrants of both sexes, age 40-69 years. Italians display significantly higher mean triglycerid...

journal_title：Human biology

authors： Mitchell RJ,Earl L,Williams J,Bisucci T,Gasiamis H

更新日期：1994-02-01 00:00:00

abstract：:Although much attention has been given to statistical genetic methods for the initial localization and fine mapping of quantitative trait loci (QTLs), little methodological work has been done to date on the problem of statistically identifying the most likely functional polymorphisms using sequence data. In this paper...

journal_title：Human biology

authors： Blangero J,Goring HH,Kent JW Jr,Williams JT,Peterson CP,Almasy L,Dyer TD

更新日期：2005-10-01 00:00:00