当前位置： SCI文献检索 > NEUROSCIENCE期刊下所有文献 > Stress axis plasticity during vestibular compensation in the adult cat.

Stress axis plasticity during vestibular compensation in the adult cat.

Abstract：

:The postural, ocular motor, perceptive and neurovegetative syndromes resulting from unilateral vestibular neurectomy (UVN) symptoms could generate a stress and thereby activate the hypothalamo-pituitary-adrenal (HPA) axis. This study was aimed at determining whether UVN causes changes in the activity of the HPA axis, and if so, evaluating the time course of changes associated with UVN syndrome. At the cellular level, corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) immunoreactivity (Ir) were analyzed and quantified in the paraventricular nucleus (PVN) and the vestibular nuclei (VN) complex of cats killed early (1 and 7 days) or late (30 and 90 days) after UVN. Dopamine-beta-hydroxylase (DbetaH), the enzyme synthesizing noradrenaline was examined in the locus coeruleus (LC) in these same cats. At the behavioral level, the time course of recovery of the postural and locomotor functions was quantified at the same postoperative delays in another group of UVN cats. Results showed a significant bilateral increase in the number of both AVP-Ir and CRF-Ir neurons in the PVN and an increase of DbetaH-Ir neurons in the LC at 1, 7 and 30 days after UVN. This increased number of neurons was no longer observed at 90 days. Conversely, a significant bilateral decrease of CRF-Ir neurons was observed in the VN at these same postlesion times, with a similar return to control values at 90 days. Our behavioral observations showed strong posturo-locomotor functional deficits early after UVN (1 and 7 days), which had recovered partially at 30 days and completely by 90 days postlesion. We demonstrate a long-lasting activation of the HPA axis, which likely reflects a chronic stress, experienced by the animals, which corresponds to the time course of full vestibular compensation, and which is no longer present when the animals are completely free of posturo-locomotor symptoms at 90 days.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Tighilet B,Manrique C,Lacour M

doi

10.1016/j.neuroscience.2009.02.070

subject

Has Abstract

pub_date

2009-06-02 00:00:00

pages

716-30

issue

4

eissn

0306-4522

issn

1873-7544

pii

S0306-4522(09)00278-4

journal_volume

160

pub_type

杂志文章

相关文献

NEUROSCIENCE文献大全
  • Delayed axonal degeneration in slow Wallerian degeneration mutant mice detected using diffusion tensor imaging.

    abstract：:Previous studies have shown the feasibility of using diffusion tensor imaging (DTI) as a noninvasive imaging modality to evaluate neurodegeneration in humans and animals. The axial and radial diffusivities derived from DTI were demonstrated to be sensitive markers for axonal and myelin damage, respectively. This study...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.09.042

    authors： Xie M,Wang Q,Wu TH,Song SK,Sun SW

    更新日期：2011-12-01 00:00:00

  • Cyclic AMP reduces adhesion of isolated neuronal growth cones from developing rat forebrain to an astrocytic cell line from embryonic mouse striatum.

    abstract：:We have recently shown that isolated neuronal growth cones from developing rat forebrain possess an appreciable activity of adenylate cyclase, producing cyclic adenosine monophosphate, which can be stimulated by various neurotransmitter receptor agonists and by forskolin [Lockerbie R. O., Hervé D., Blanc G., Tassin J....

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(89)90191-7

    authors： Lockerbie RO,Autillo-Touati A,Araud D,Seite R,Chneiweiss H,Glowinski J,Prochiantz A

    更新日期：1989-01-01 00:00:00

  • Evidence of GABA-immunopositive neurons in the dorsal part of the lateral geniculate nucleus of reptiles: morphological correlates with interneurons.

    abstract：:The distribution and staining pattern of gamma-aminobutyric acid immunoreactivity have been examined by both light and electron microscopy in the dorsal part of the lateral geniculate nucleus of three reptilian species: the turtle Chinemys reevesi, the lizard Ophisaurus apodus and the snake Vipera aspis. After perfusi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(92)90254-y

    authors： Rio JP,Reperant J,Ward R,Miceli D,Medina M

    更新日期：1992-01-01 00:00:00

  • Evidence that integrins contribute to multiple stages in the consolidation of long term potentiation in rat hippocampus.

    abstract：:Three structurally distinct groups of antagonists were used to test the hypothesis that integrin adhesion receptors play an essential role in consolidating (stabilizing) long term potentiation of the Schaffer collaterals in rat hippocampus. Comparisons were made of percent potentiation at antagonist-treated versus con...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(01)00173-7

    authors： Chun D,Gall CM,Bi X,Lynch G

    更新日期：2001-01-01 00:00:00

  • Er81 is expressed in a subpopulation of layer 5 neurons in rodent and primate neocortices.

    abstract：:Laminar organization is a fundamental cytoarchitecture in mammalian CNS and a striking feature of the neocortex. ER81, a transcription factor, has recently been utilized as a marker of cells in the layer 5 of the neocortex. We further pursued the distribution of ER81 to investigate the identity of the ER81-expressing ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2005.08.075

    authors： Yoneshima H,Yamasaki S,Voelker CC,Molnár Z,Christophe E,Audinat E,Takemoto M,Nishiwaki M,Tsuji S,Fujita I,Yamamoto N

    更新日期：2006-01-01 00:00:00

  • Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein.

    abstract：:Synucleinopathies including Parkinson's disease (PD) are characterized by the accumulation of alpha-synuclein (α-syn) within neural cell bodies and their processes. Transgenic mice overexpressing human wild-type or mutant forms of α-syn under the control of different promoters were developed to analyse the underlying ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2012.07.001

    authors： May VE,Nuber S,Marxreiter F,Riess O,Winner B,Winkler J

    更新日期：2012-10-11 00:00:00

  • Serotonin-induced in vitro long-term facilitation exhibits differential pattern sensitivity in cervical and thoracic inspiratory motor output.

    abstract：:Intermittent hypoxia induces 5-HT-dependent, pattern-sensitive long-term facilitation (LTF) of spinal respiratory motor output. We used a split-bath in vitro neonatal rat brainstem-spinal cord preparation to test whether: 1) intermittent spinal 5-HT exposure (without hypoxia) is sufficient to induce LTF in phrenic and...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2006.06.036

    authors： Lovett-Barr MR,Mitchell GS,Satriotomo I,Johnson SM

    更新日期：2006-10-27 00:00:00

  • Expression of PAC 1, an epitope associated with two synapse-enriched glycoproteins and a neuronal cytoskeleton-associated polypeptide in developing forebrain neurons.

    abstract：:The monoclonal antibody PAC 1 (postsynaptic density and cytoskeleton enriched) recognizes an epitope present on two postsynaptic density-enriched glycoproteins of 130,000 (postsynaptic density-enriched glycoprotein 130) and 117,000 mol. wt (postsynaptic density-enriched glycoprotein 117), and a cytoskeleton-enriched p...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)90159-7

    authors： Willmott T,Williamson TL,Mummery R,Hawkes RB,Can A,Gurd JW,Gordon-Weeks PR,Beesley PW

    更新日期：1994-01-01 00:00:00

  • Increased expression of the N-methyl-D-aspartate receptor subunit, NR1, in immunohistochemically identified magnocellular hypothalamic neurons during dehydration.

    abstract：:N-Methyl-D-aspartate receptors are thought to be involved in synaptic signaling within the hypothalamo-neurohypophysial system, but the extent and nature of their involvement has not been determined. In this study, in the rat, we evaluated the effect of hyperosmotic stimulation on the N-methyl-D-aspartate receptor sub...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(96)00544-1

    authors： Decavel C,Curras MC

    更新日期：1997-05-01 00:00:00

  • GDNF-secreting mesenchymal stem cells provide localized neuroprotection in an inflammation-driven rat model of Parkinson's disease.

    abstract：:Constraints involving the delivery method of glial cell line-derived neurotrophic factor (GDNF) have hampered its efficacy as a neuroprotectant in Parkinson's disease. Ex vivo gene therapy, in which suitable cells, such as bone marrow-derived mesenchymal stem cells (MSCs), are genetically engineered to overexpress GDN...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.07.014

    authors： Hoban DB,Howard L,Dowd E

    更新日期：2015-09-10 00:00:00

  • Angiotensin II induces a complex activation of transcription factors in the rat brain: expression of Fos, Jun and Krox proteins.

    abstract：:We investigated the effects of intracerebroventricular injection of angiotensin II on neuronal immediate early gene-encoded protein synthesis in the brain of conscious rats. The expression of seven immediate early gene-encoded transcription factors (c-Fos, FosB, c-Jun, JunB, JunD, Krox-20 (Egr-2) and Krox-24 (NGFI-A, ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)00482-k

    authors： Lebrun CJ,Blume A,Herdegen T,Seifert K,Bravo R,Unger T

    更新日期：1995-03-01 00:00:00

  • Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring.

    abstract：:The Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD) exhibits cognitive impairment and degeneration of basal forebrain cholinergic neurons (BFCNs). Our prior studies demonstrated that maternal choline supplementation (MCS) improves attention and spatial cognition in Ts65Dn offspring, normalizes hi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2016.11.001

    authors： Powers BE,Kelley CM,Velazquez R,Ash JA,Strawderman MS,Alldred MJ,Ginsberg SD,Mufson EJ,Strupp BJ

    更新日期：2017-01-06 00:00:00

  • Muscarinic cholinergic and glutamatergic reciprocal regulation of expression of hippocampal cholinergic neurostimulating peptide precursor protein gene in rat hippocampus.

    abstract：:Hippocampal cholinergic neurostimulating peptide, an undecapeptide originally isolated from the hippocampus of young rats, enhances acetylcholine synthesis in rat medial septal nucleus in vitro. Hippocampal cholinergic neurostimulating peptide is derived from the N-terminal region of its 21-kmol.wt precursor protein. ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(00)00495-4

    authors： Iwase T,Ojika K,Matsukawa N,Nishino H,Yamamoto T,Okada H,Fujimori O,Ueda R

    更新日期：2001-01-01 00:00:00

  • Chitinase1 contributed to a potential protection via microglia polarization and Aβ oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments.

    abstract：:Chitinase activity is increased in Alzheimer's disease (AD). However, the role of chitinase1 in AD is unknown. We investigated the effects of chitinase1 on Alzheimer's pathology and microglia function. Artificial chitinase1 and chitinase inhibitor (chitinase-IN-2) were used to determine the effects of chitinase1 on in...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.04.050

    authors： Xiao Q,Yu W,Tian Q,Fu X,Wang X,Gu M,Lü Y

    更新日期：2017-07-04 00:00:00

  • Evidence for presynaptic 5-hydroxytryptamine3 recognition sites on vagal afferent terminals in the brainstem of the ferret.

    abstract：:Antagonists acting at the 5-hydroxytryptamine3 receptor are potent anti-emetic agents in cases of cytotoxic- and radiation-induced vomiting, and binding sites for these compounds have been described in brainstem areas known to be involved in mediation of nausea and vomiting. We have used autoradiography to examine the...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(90)90060-h

    authors： Leslie RA,Reynolds DJ,Andrews PL,Grahame-Smith DG,Davis CJ,Harvey JM

    更新日期：1990-01-01 00:00:00

  • Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation.

    abstract：:Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that can be released or activated in a neuronal activity dependent manner. Although pathologically elevated levels of MMPs may be synaptotoxic, physiologically appropriate levels of MMPs may instead enhance synaptic transmission. MMP inhibi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.12.061

    authors： Conant K,Wang Y,Szklarczyk A,Dudak A,Mattson MP,Lim ST

    更新日期：2010-03-17 00:00:00

  • Operating in a Multisensory Context: Assessing the Interplay Between Multisensory Reaction Time Facilitation and Inter-sensory Task-switching Effects.

    abstract：:Individuals respond faster to presentations of bisensory stimuli (e.g. audio-visual targets) than to presentations of either unisensory constituent in isolation (i.e. to the auditory-alone or visual-alone components of an audio-visual stimulus). This well-established multisensory speeding effect, termed the redundant ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2020.04.013

    authors： Shaw LH,Freedman EG,Crosse MJ,Nicholas E,Chen AM,Braiman MS,Molholm S,Foxe JJ

    更新日期：2020-06-01 00:00:00

  • Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.

    abstract：:The distribution of neuropeptide Y immunoreactive cell bodies in relation to various types of catecholamine-containing cell bodies in the rat brain was analyzed immunohistochemically using antisera to tyrosine hydroxylase, dopamine beta-hydroxylase and phenylethanolamine N-methyltransferase. Coexistence of the peptide...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(84)90036-8

    authors： Everitt BJ,Hökfelt T,Terenius L,Tatemoto K,Mutt V,Goldstein M

    更新日期：1984-02-01 00:00:00

  • An autoradiographic analysis of ascending projections from the medullary reticular formation in the rat.

    abstract：:Ascending projections from the several nuclei of the medullary reticular formation were examined using the autoradiographic method. The majority of fibers labeled after injections of [3H]leucine into nucleus gigantocellularis ascended within Forel's tractus fasciculorum tegmenti which is located ventrolateral to the m...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(86)90305-2

    authors： Vertes RP,Martin GF,Waltzer R

    更新日期：1986-11-01 00:00:00

  • Whole transcriptome expression of trigeminal ganglia compared to dorsal root ganglia in Rattus Norvegicus.

    abstract：:The trigeminal ganglia (TG) subserving the head and the dorsal root ganglia (DRG) subserving the rest of the body are homologous handling sensory neurons. Differences exist, as a number of signaling substances cause headache but no pain in the rest of the body. To date, very few genes involved in this difference have ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.03.027

    authors： Kogelman LJA,Christensen RE,Pedersen SH,Bertalan M,Hansen TF,Jansen-Olesen I,Olesen J

    更新日期：2017-05-14 00:00:00

  • Functional GABA(B) receptors are expressed at the cone photoreceptor terminals in bullfrog retina.

    abstract：:GABA(B) receptors at the cone terminals in bullfrog retina were characterized by immunocytochemical and whole-cell patch clamp techniques in retinal slice preparations. Somata, axons and synaptic terminals (pedicles) of cones were both GABA(B) receptor (GABA(B)R) 1 and GABA(B)R2 immunoreactive. Physiologically, barium...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2004.12.024

    authors： Liu J,Zhao JW,Du JL,Yang XL

    更新日期：2005-01-01 00:00:00

  • Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells.

    abstract：:Insulin plays diverse roles, including learning and memory, in the central nervous system. SIRT1 has been reported to be involved in the processes of normal learning, memory, and synaptic plasticity. However, whether insulin is directly involved in regulating SIRT1 expression in neurons or whether it affects synapses ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.01.034

    authors： Liu Y,Yao Z,Zhang L,Zhu H,Deng W,Qin C

    更新日期：2013-05-15 00:00:00

  • Projections from the rostral parvocellular reticular formation to pontine and medullary nuclei in the rat: involvement in autonomic regulation and orofacial motor control.

    abstract：:The efferent connections of the rostral parvocellular reticular formation to pontine and medullary nuclei in the rat were studied with anterogradely transported Phaseolus vulgaris leucoagglutinin. Dense innervations from the rostral parvocellular reticular formation were found in the mesencephalic trigeminal nucleus, ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(91)90009-d

    authors： Ter Horst GJ,Copray JC,Liem RS,Van Willigen JD

    更新日期：1991-01-01 00:00:00

  • Electrophysiological characteristics of inhibitory neurons of the prepositus hypoglossi nucleus as analyzed in Venus-expressing transgenic rats.

    abstract：:The identification and characterization of excitatory and inhibitory neurons are significant steps in understanding neural network functions. In this study, we investigated the intrinsic electrophysiological properties of neurons in the prepositus hypoglossi nucleus (PHN), a brainstem structure that is involved in gaz...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.09.017

    authors： Shino M,Kaneko R,Yanagawa Y,Kawaguchi Y,Saito Y

    更新日期：2011-12-01 00:00:00

  • Cloning and serotonergic regulation of RING finger protein38 (rnf38) in the brain of medaka (Oryzias latipes).

    abstract：:Serotonin (5-HT) is a key regulator of mood and sexual behaviors. 5-HT reuptake inhibitors have been used as antidepressants. Really interesting new gene (RING) finger proteins have been associated with 5-HT regulation but their role remains largely unknown. Some RING finger proteins are involved in the serotonergic s...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.03.012

    authors： Moriya S,Khel NB,Parhar IS

    更新日期：2015-05-21 00:00:00

  • Facilitated induction of hippocampal long-term potentiation in slices perfused with low concentrations of magnesium.

    abstract：:The generation of long-term potentiation of synaptic transmission in area CA1 of hippocampal slices of the guinea-pig has been examined in solutions containing low concentrations of magnesium ions. It was found that the induction of long-term potentiation is greatly facilitated in slices perfused with 0.1 mM magnesium...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(87)90193-x

    authors： Huang YY,Wigström H,Gustafsson B

    更新日期：1987-07-01 00:00:00

  • Expression of a developmentally regulated, phosphorylated isoform of microtubule-associated protein 1B in regenerating axons of the sciatic nerve.

    abstract：:Monoclonal antibodies SMI-31 and 150 recognize phosphorylation epitopes on microtubule-associated protein 1B that have been shown to be developmentally down-regulated in the nervous system. We have used these antibodies to establish changes in the pattern of expression of their epitopes on microtubule-associated prote...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(96)00078-4

    authors： Bush MS,Tonge DA,Woolf C,Gordon-Weeks PR

    更新日期：1996-07-01 00:00:00

  • Ectopic sympathetic preganglionic neurons maintain proper connectivity in the reeler mutant mouse.

    abstract：:The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal. Instead of their normal location in the intermediolateral column, the majority of SPN in the reeler cluster around the central canal. To determine whether ectopically located SPN in the reeler form approp...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(02)00945-4

    authors： Yip YP,Rinaman L,Capriotti C,Yip JW

    更新日期：2003-01-01 00:00:00

  • P2X7-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms.

    abstract：:Recent studies demonstrate that P2X7 receptor subunits (P2X7RS) are present at central and peripheral synapses and suggest that P2X7RS can regulate transmitter release. In brainstem slices from 15 to 26 day old pentobarbitone-anesthetized mice, we examined the effect of P2X7RS activation on excitatory postsynaptic cur...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2004.06.014

    authors： Ireland MF,Noakes PG,Bellingham MC

    更新日期：2004-01-01 00:00:00

  • Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: their projections in the guinea-pig small intestine.

    abstract：:Changes in the distribution of 5-hydroxytryptamine-like immunoreactivity have been examined in enteric neurons at various times after microsurgical lesions of the enteric plexuses. In the myenteric plexus, varicose immunoreactive nerve fibres disappeared or were reduced in number in ganglia anal to an interruption of ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(82)90271-8

    authors： Furness JB,Costa M

    更新日期：1982-02-01 00:00:00