Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG.

abstract：:By immunoaffinity column chromatography, we have purified two RNA polymerase complexes, the transcriptase and replicase, from vesicular stomatitis virus-infected baby hamster kidney cells. The transcriptase is a multiprotein complex, containing the virus-encoded RNA polymerase L and P proteins, and two cellular protei...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Qanungo KR,Shaji D,Mathur M,Banerjee AK

更新日期：2004-04-20 00:00:00

abstract：:Global demand for agricultural products such as food, feed, and fuel is now a major driver of cropland and pasture expansion across much of the developing world. Whether these new agricultural lands replace forests, degraded forests, or grasslands greatly influences the environmental consequences of expansion. Althoug...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gibbs HK,Ruesch AS,Achard F,Clayton MK,Holmgren P,Ramankutty N,Foley JA

更新日期：2010-09-21 00:00:00

abstract：:In order to study the mutagenic effects of site-specific, covalent modifications of biologically active DNA, we need host cells that are permissive for any type of mutation that might be produced in vivo from the modified DNA. Specifically, we require a general, in vivo complementation system for the bacteriophage phi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Humayun MZ,Chambers RW

更新日期：1978-02-01 00:00:00

abstract：:The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate the molecular organization of the adult mammalian brain, we have built a gene expression-based brain map. We measured gene expression patterns for 24 neural ti...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zapala MA,Hovatta I,Ellison JA,Wodicka L,Del Rio JA,Tennant R,Tynan W,Broide RS,Helton R,Stoveken BS,Winrow C,Lockhart DJ,Reilly JF,Young WG,Bloom FE,Lockhart DJ,Barlow C

更新日期：2005-07-19 00:00:00

abstract：:Highly purified RNA polymerase II was found to be able to weakly recognize the initiator (Inr) present in the adenovirus IVa2 and major late promoters. The association of RNA polymerase II with the Inr was enhanced by the general transcription factors. The Inr was capable of directing the formation of a DNA-protein co...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Carcamo J,Buckbinder L,Reinberg D

更新日期：1991-09-15 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1), released from gut endocrine L cells in response to glucose, regulates appetite, insulin secretion, and gut motility. How glucose given orally, but not systemically, induces GLP-1 secretion is unknown. We show that human duodenal L cells express sweet taste receptors, the taste G protei...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jang HJ,Kokrashvili Z,Theodorakis MJ,Carlson OD,Kim BJ,Zhou J,Kim HH,Xu X,Chan SL,Juhaszova M,Bernier M,Mosinger B,Margolskee RF,Egan JM

更新日期：2007-09-18 00:00:00

abstract：:During reverse transcription of retroviral RNA, synthesis of (-) strand DNA is primed by a cellular tRNA that anneals to an 18-nt primer binding site within the 5' long terminal repeat. For (+) strand synthesis using a (-) strand DNA template linked to the tRNA primer, only the first 18 nt of tRNA are replicated to re...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Burnett BP,McHenry CS

更新日期：1997-07-08 00:00:00

abstract：:URF13 is a mitochondrially encoded, integral membrane protein found only in maize carrying the cms-T cytoplasm. URF13 is associated with cytoplasmic male sterility, Texas type, and causes susceptibility to the fungal pathogens Bipolaris maydis race T and Phyllosticta maydis. URF13 is predicted to contain three transme...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Rhoads DM,Kaspi CI,Levings CS 3rd,Siedow JN

更新日期：1994-08-16 00:00:00

abstract：:Formamide is one of the important compounds from which prebiotic molecules can be synthesized, provided that its concentration is sufficiently high. For nucleotides and short DNA strands, it has been shown that a high degree of accumulation in hydrothermal pores occurs, so that temperature gradients might play a role ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Niether D,Afanasenkau D,Dhont JK,Wiegand S

更新日期：2016-04-19 00:00:00

abstract：:Chromatin insulators or boundaries are proposed to structure the chromatin fiber into functionally independent domains by promoting the formation of chromatin loops. These elements can block the communication between an enhancer and a gene when placed between them. Interestingly, it has been previously observed that t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Melnikova L,Juge F,Gruzdeva N,Mazur A,Cavalli G,Georgiev P

更新日期：2004-10-12 00:00:00

abstract：:Ischemia and reperfusion both contribute to tissue damage after myocardial infarction. Although many drugs have been shown to reduce infarct size when administered before ischemia, few have been shown to be effective when administered at reperfusion. Moreover, although it is generally accepted that a burst of reactive...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Granville DJ,Tashakkor B,Takeuchi C,Gustafsson AB,Huang C,Sayen MR,Wentworth P Jr,Yeager M,Gottlieb RA

更新日期：2004-02-03 00:00:00

abstract：:Drosophila ovo/svb (dovo) is required for epidermal cuticle/denticle differentiation and is genetically downstream of the wg signaling pathway. Similarly, a mouse homolog of dovo, movo1, is required for the proper formation of hair, a mammalian epidermal appendage. Here, we provide biochemical evidence that movo1 enco...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Li B,Mackay DR,Dai Q,Li TW,Nair M,Fallahi M,Schonbaum CP,Fantes J,Mahowald AP,Waterman ML,Fuchs E,Dai X

更新日期：2002-04-30 00:00:00

abstract：:The immune response is normally controlled by regulatory T cells (Tregs). However, Treg deficits are found in autoimmune diseases, and therefore the induction of functional Tregs is considered a potential therapeutic approach for autoimmune disorders. The activation of the ligand-activated transcription factor aryl hy...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yeste A,Nadeau M,Burns EJ,Weiner HL,Quintana FJ

更新日期：2012-07-10 00:00:00

abstract：:The amino-terminal 20 amino acids are required for microinjected ribonuclease A (RNase A) to be taken up by lysosomes and degraded at an enhanced rate during serum withdrawal. We used water-soluble carbodiimides to covalently attach the RNase S-peptide (residues 1-20) to [3H]RNase S-protein (residues 21-124) at unspec...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Backer JM,Dice JF

更新日期：1986-08-01 00:00:00

abstract：:We image macroscopic transient pores in mechanically stretched giant vesicles. Holes open above a critical radius r(c1), grow up to a radius r(c2), and close. We interpret the upper limit r(c2) by a relaxation of the membrane tension as the holes expand. The closing of the holes is caused by a further relaxation of th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sandre O,Moreaux L,Brochard-Wyart F

更新日期：1999-09-14 00:00:00

abstract：:We resolve the 3D trajectory and the orientation of individual cells for extended times, using a digital tracking technique combined with 3D reconstructions. We have used this technique to study the motility of the uniflagellated bacterium Caulobacter crescentus and have found that each cell displays two distinct mode...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu B,Gulino M,Morse M,Tang JX,Powers TR,Breuer KS

更新日期：2014-08-05 00:00:00

abstract：:Phagocytes are a critical component of the innate immune response in humans and eliminate invading microorganisms through a process known as phagocytosis. Two distinct receptor-linked phagocytic pathways, one with Ab receptors (FcRs; FcR, Fc receptor) and the other complement receptors (CRs), mediate binding and inges...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kobayashi SD,Voyich JM,Buhl CL,Stahl RM,DeLeo FR

更新日期：2002-05-14 00:00:00

abstract：:Accurate calculations of force generated and of ATP flux, in steady isotonic contractions, are made on a simple, two-state muscle model of the sliding filament type. The objective is to illustrate the proper formulation and use of a complete and self-consistent molecular model of muscle. Otherwise, the model is not me...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chen YD,Hill TL

更新日期：1974-05-01 00:00:00

abstract：:Golgi-associated cytoplasmic proteins, such as the coatomer protein complex, are required for vesicle budding and trafficking. We have previously described a cytoplasmic phosphoprotein, p200, which binds dynamically and specifically to Golgi membranes. The p200 protein is dissociated from Golgi membranes in the presen...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Narula N,Stow JL

更新日期：1995-03-28 00:00:00

abstract：:Initial attempts to correlate the distribution of gene density (number of gene loci per unit length on the linkage map) with the distribution of lengths of coding sequences have led to the observation that 46% of approximately 1000 sampled proteins in Escherichia coli have molecular masses of n X 14,000 +/- 2500 dalto...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Savageau MA

更新日期：1986-03-01 00:00:00

abstract：:Little is known about the molecular mechanisms by which the embryo proper and suspensor of plant embryos activate specific gene sets shortly after fertilization. We analyzed the upstream region of the scarlet runner bean (Phaseolus coccineus) G564 gene to understand how genes are activated specifically within the susp...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kawashima T,Wang X,Henry KF,Bi Y,Weterings K,Goldberg RB

更新日期：2009-03-03 00:00:00

abstract：:The recently discovered potato tuber (Solanum tuberosum) alpha-glucan, water dikinase (GWD) (formerly known as R1) catalyzes the phosphorylation of starch by a dikinase-type reaction mechanism in which the beta-phosphate of ATP is transferred to either the C-6 or the C-3 position of the glucosyl residue of starch. In ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mikkelsen R,Mutenda KE,Mant A,Schürmann P,Blennow A

更新日期：2005-02-01 00:00:00

abstract：:In normal vision, shifts of attention are usually followed by saccadic eye movements. Neurons in extrastriate area V4 are modulated by focal attention when eye movements are withheld, but they also respond in advance of visually guided saccadic eye movements. We have examined the visual selectivity of saccade-related ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moore T,Tolias AS,Schiller PH

更新日期：1998-07-21 00:00:00

abstract：:BALB/c mice immunized with syngeneic methylcholanthrene-induced fibrosarcomas did not have antibodies against the unique tumor-specific transplantation antigens, even though they were capable of rejecting a lethal dose of tumor cells. Endogenous murine leukemia virus antigens expressed by certain of the tumors did, ho...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Brown JP,Klitzman JM,Hellström I,Nowinski RC,Hellström KE

更新日期：1978-02-01 00:00:00

abstract：:Ca2+/calmodulin-dependent protein kinase enriched in cerebellar granule cells (CaM kinase Gr) is a neuronal calmodulin-dependent protein kinase whose purification and partial cloning from rat brain has been described. A combination of the polymerase chain reaction and cDNA library screening was used to determine the D...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ohmstede CA,Bland MM,Merrill BM,Sahyoun N

更新日期：1991-07-01 00:00:00

abstract：:Homeodomain-interacting protein kinase-2 (HIPK2) is a serine/threonine kinase involved in transcriptional regulation and apoptosis. The transcriptional corepressor CtBP (carboxyl-terminal binding protein) also plays a fundamental role in these processes. Our previous studies indicate that HIPK2 participates in a pathw...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zhang Q,Nottke A,Goodman RH

更新日期：2005-02-22 00:00:00

abstract：:Two operators, spatially separated from each other and from the promoters, repress the gal operon when bound to Gal repressor. Conversion of either gal operator to a lac operator results in derepression, although both Gal and Lac repressors are present, suggesting that mere occupation of operator sites is not sufficie...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Haber R,Adhya S

更新日期：1988-12-01 00:00:00

abstract：:Loss-of-function DJ-1 mutations can cause early-onset Parkinson's disease. The function of DJ-1 is unknown, but an acidic isoform accumulates after oxidative stress, leading to the suggestion that DJ-1 is protective under these conditions. We addressed whether this represents a posttranslational modification at cystei...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Canet-Avilés RM,Wilson MA,Miller DW,Ahmad R,McLendon C,Bandyopadhyay S,Baptista MJ,Ringe D,Petsko GA,Cookson MR

更新日期：2004-06-15 00:00:00

abstract：:The present investigation studied the influence of the blastocyst's state of activity on the "window" of implantation in the receptive uterus in the mouse. The receptive state of the uterus is defined as the limited time when the uterine milieu is favorable to blastocyst acceptance and implantation. In the mouse, impl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Paria BC,Huet-Hudson YM,Dey SK

更新日期：1993-11-01 00:00:00

abstract：:Facilitation of social attraction and bonding by the evolutionarily conserved neuropeptide oxytocin is well-established in female mammals. However, accumulating behavioral evidence suggests that oxytocin may have evolved sex-specific functional roles in the domain of human social cognition. A critical question is how ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gao S,Becker B,Luo L,Geng Y,Zhao W,Yin Y,Hu J,Gao Z,Gong Q,Hurlemann R,Yao D,Kendrick KM

更新日期：2016-07-05 00:00:00