Abstract:
BACKGROUND:Cardiovascular complications are considered a significant problem in patients with chronic kidney disease (CKD). Body surface potential mapping (BSPM) is a noninvasive method that is useful in detecting early changes involving the heart. The aim of the study was to evaluate possible abnormalities within the cardiac intraventricular conduction system in young patients with CKD using the BSPM method. METHODS:Based on the BSPM registrations, the QRS-T isointegral maps were created in 42 young patients with CKD (on hemodialysis, subgroup Ia; on peritoneal dialysis, subgroup Ib; on conservative treatment, group II) and in 26 healthy subjects. Serum levels of electrolytes, urea, and creatinine were also assessed in the entire study population. RESULTS:In the healthy subjects, the maximums of the group mean QRS-T isointegral map were located in the left lower anterior part of the thorax, whereas in the Ia patients, the maximums were focused at the medial sternum line. The QRS-T maps, both for Ib and II groups, showed the positive integrals covering the left part of the anterior thorax. In all the patients with CKD, standard 12-lead electrocardiogram (ECG) and echocardiography findings were within the reference range. CONCLUSIONS:In the hemodialyzed patients with CKD, the group-mean QRS-T isointegral map distribution suggested a significant delay of excitation propagation in the left bundle branch, although no abnormalities were found with standard ECG. In the patients with CKD treated with peritoneal dialysis or conservatively, the group-mean QRS-T isointegral maps were characteristic for the early phase of conduction disturbances within the left bundle branch, which again was not observed on the standard ECG recordings.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Polak-Jonkisz D,Laszki-Szczachor K,Purzyc L,Zwolińska D,Musiał K,Pilecki W,Rusiecki L,Janocha A,Kałka D,Sobieszczańska Mdoi
10.1016/j.jelectrocard.2008.09.007subject
Has Abstractpub_date
2009-03-01 00:00:00pages
165-71issue
2eissn
0022-0736issn
1532-8430pii
S0022-0736(08)00365-8journal_volume
42pub_type
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journal_title:Journal of electrocardiology
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pub_type: 临床试验,杂志文章
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2001.22028
更新日期:2001-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2012.02.004
更新日期:2012-05-01 00:00:00
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2005.06.036
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pub_type: 杂志文章,评审
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journal_title:Journal of electrocardiology
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更新日期:2017-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.10.005
更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章
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