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Estimates of repolarization and its dispersion from electrocardiographic measurements: direct epicardial assessment in the canine heart.

Abstract：

:This study investigates a technique to estimate dispersion based on the root mean square (RMS) signal of multiple electrocardiographic leads. Activation and recovery times were measured from 64 sites on the epicardium of canine hearts using acute in situ or Langendorff perfused isolated heart preparations. Repolarization and its dispersion were altered by varying cycle length, myocardial temperature, or ventricular pacing site. Mean and dispersion of activation and recovery times, and activation-recovery interval (ARI) were calculated for each beat. The waveform was then calculated from all leads. Estimates of mean and dispersion of activation and recovery times and mean ARI were derived using only inflection points from the RMS waveform. QT intervals were also measured and QT dispersion was determined. Estimates determined from the RMS waveform provided accurate estimates of repolarization and were, in particular, a better measure of repolarization dispersion than QT dispersion.

journal_name

J Electrocardiol

journal_title

Journal of electrocardiology

authors

Fuller MS,Sándor G,Punske B,Taccardi B,MacLeod RS,Ershler PR,Green LS,Lux RL

doi

10.1016/s0022-0736(00)80073-4

keywords:

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

171-80

issue

2

eissn

0022-0736

issn

1532-8430

pii

S0022073600000182

journal_volume

33

pub_type

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