Abstract：
:An academic 12-lead electrocardiogram (ECG) core laboratory aims to provide the highest possible quality ECG recording, measurement, and storage to aid clinicians in research into important cardiovascular outcomes and to maximize the credibility of scientific results based solely, or in part, on ECG data. This position paper presents a guide for the structure and function of an academic ECG core laboratory. The key functional aspects are: 1) Data collection, 2) Staff composition, 3) Diagnostic measurement and definition standards, 4) Data management, 5) Academic considerations, 6) Economic consideration, and 7) Accreditation. An ECG Core Laboratory has the responsibility for rapid and accurate analysis and responsible management of the electrocardiographic data in multicenter clinical trials. Academic Laboratories, in addition, provide leadership in research protocol generation and production of research manuscripts for submission to the appropriate peer-review journals.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Anderson ST,Pahlm O,Bacharova L,Barbagelata A,Chaitman BR,Clemmensen P,Goodman S,Hedén B,Klootwijk PJ,Lauer M,MacFarlane PW,Rautaharju P,Reddy S,Selvester RH,Sgarbossa EB,Underwood D,Warner RA,Wagner GSdoi
10.1054/jelc.2001.22028keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
41-7issue
1eissn
0022-0736issn
1532-8430pii
S002207360124179Xjournal_volume
34pub_type
杂志文章abstract：:Cardiac gap junctions are responsible for normal conduction properties of the ventricles. Alteration in gap junction distribution (remodeling) in ischemic heart disease is likely to be an important cause of life threatening ventricular arrhythmias. ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2001.28834
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:No direct comparison of current electrocardiogram (ECG) interpretation programs exists. OBJECTIVE:Assess the accuracy of ECG interpretation programs in detecting abnormal rhythms and flagging for priority review records with alterations secondary to acute coronary syndrome (ACS). METHODS:More than 2,000 di...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.11.043
更新日期：2020-01-01 00:00:00
abstract：AIM:To evaluate the diagnostic accuracy of electrocardiographic inferior Q waves persistence during inspiration and echocardiographic segmental wall motion abnormalities for the detection of previously unsuspected silent myocardial infarction, by using cardiac magnetic resonance as the gold standard. METHODS:We prospe...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.08.026
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:In a minority of the patients presenting with ST-segment elevation (STE) myocardial infarction (MI), electrocardiogram (ECG) may show a balanced STE in both anterior and inferior lead groups and may cause diagnostic confusion about involved myocardial territory. In this study, we sought ECG clues which may f...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2018.09.006
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Interatrial block (IAB; P waves >/= 110 milliseconds), the conduction delay between the right (RA) and left atrium (LA), is depicted on the electrocardiogram (ECG) as prolonged, often bifid ("notched"), P waves with distinguishable RA and LA components. Although electrophysiologic (EP) studies give some insi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2005.11.002
更新日期：2006-10-01 00:00:00
abstract：:Junctional ectopic tachycardia(JET) is a rare childhood arrhythmia originating from the area adjacent to the atrioventricular(AV) node. It often occurs after surgical procedures like repair of Tetralogy of Fallot, atrioventricular septal defect and ventricular septal defect, which are all performed in that area. While...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.01.015
更新日期：2017-01-01 00:00:00
abstract：:In 19 pentobarbital anesthetized dogs subjected to right thoracotomy, plunge wire and catheter electrodes were positioned to record and pace from the high right atrium, coronary sinus os, aortic root (for His bundle electrograms), and the right ventricular outflow tract and apex. A deflectable-tip catheter electrode w...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Syncope is a risk factor for sudden cardiac death (SCD) in many conditions associated with structural heart disease as well as inherited heart disease. The ECG in patients with syncope should be examined carefully for signs of structural heart disease, such as myocardial infarction or cardiomyopathy; signs of conducti...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2013.07.008
更新日期：2013-11-01 00:00:00
abstract：:High-resolution (HI-RES) ECG analysis software and a new front end have been designed for a standard 12-lead ECG cart, MAC-12. The front end acquires orthogonal ECG at 1,000 samples/sec and 1.2 microV/bit and transmits to the cart. The HI-RES software delineates QRS complexes and correlates them with a template in fre...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(88)90062-3
更新日期：1988-01-01 00:00:00
abstract：:Bidirectional tachycardia was observed on Holter tracings recorded from a dog three days after the production of a small freeze lesion on the wall of the left ventricle. A bigeminal rhythm with fixed coupling of ventricular premature contractions was interrupted by a burst of ventricular tachycardia of different morph...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(79)80046-1
更新日期：1979-01-01 00:00:00
abstract：:The dominant T wave (DTW) reflects the derivative of the repolarization phase of the transmembrane potential of myocytes. T-wave alternans (TWA) is defined as an alteration of this repolarization that repeats every other beat. We investigate if the DTW can offer new insight on TWA. We first proved that the DTW estimat...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.11.017
更新日期：2011-03-01 00:00:00
abstract：AIM:LBBB in heart failure patients has prognostic significance. Subtypes of LBBB (concordant and discordant) have not been considered when considering management. The aim of this study is to explore the clinical difference between the two subtypes. METHODS:216 patients with LBBB were included and categorized into conc...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.08.031
更新日期：2016-01-01 00:00:00
abstract：:A 52-year-old woman exhibited Mobitz type II atrioventricular block with right bundle branch block and 1:1 atrioventricular conduction at or slower than 80 beats/min. Electrophysiologic study revealed transient HV interval block followed by recovery from the block at shorter coupling intervals without prolongation of ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(98)90009-7
更新日期：1998-01-01 00:00:00
abstract：:From 81,000 ECGs we collected 83 cases that fulfilled the criteria of Interatrial Conduction Disturbances with Left Atrial Retrograde Activation (IACD-LARA) (P +/- in II, III and VF with P width greater than or equal to 120 msec.). We present the detailed study of 35 cases with surface ECG and VCG and 29 cases with or...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(85)80029-7
更新日期：1985-01-01 00:00:00
abstract：:The left ventricle (LV) plays a central role in the maintenance of health of children and adults due to its role as the major pump of the heart. In cases of LV dysfunction, a significant percentage of affected individuals develop signs and symptoms of congestive heart failure, leading to the need for therapeutic inter...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1054/jelc.2001.28859
更新日期：2001-01-01 00:00:00
abstract：:The electrocardiographic criteria for isolated left anterior fascicular block are reviewed and illustrated. Left anterior fascicular block decreases the voltage in the chest leads and increases the voltage in the limb leads. The usual voltage criteria of left ventricular hypertrophy must be modified appropriately. Cha...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(83)80024-7
更新日期：1983-04-01 00:00:00
abstract：:This article concerns a currently reported hypothesis explaining the alternations of conduction time during intra atrioventricular (AV) nodal reentrant tachycardia (AVNRT). This hypothesis supposes simple mutual influence of sequences of intranodal conduction during reentry tachycardia that use the same circuit in dif...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(89)90024-1
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVE:The clinical benefit of percutaneous coronary intervention (PCI) is controversial in ST-segment elevation myocardial infarction (STEMI) patients presenting 12-72 hours after symptom onset. Several studies suggested this conflicting result was associated with myocardial area at risk (MaR) of enrolled patients....
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.01.004
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:As technology infiltrates more of our personal and professional lives, user expectations for intuitive design have driven many consumer products, while medical equipment continues to have high training requirements. Not much is known about the usability and user experience associated with hospital monitoring...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.08.032
更新日期：2015-11-01 00:00:00
abstract：:Left ventricular systolic function, determined mainly by final infarct size, has a major influence on prognosis after acute myocardial infarction (MI). It was found that infarct size and left ventricular ejection fraction can be predicted using the Selvester QRS-score in patients not receiving reperfusion therapy. We ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.200.20345
更新日期：2000-01-01 00:00:00
abstract：:A comparison was made of the electrophysiological properties of the fibers between the previously reported conduction pathways from the left atrium to the right atrium and to the ventricle (left A-V ring pathways) and the ordinary atrial muscle, using perfused isolated rabbit hearts. Each fiber within these pathways s...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(80)80006-9
更新日期：1980-01-01 00:00:00
abstract：:Reliable cardiovascular (CV) risk assessment by a noninvasive tool would be of great value for CV event prevention. The present study consists of 187 coronary artery disease patients with 8 years of follow-up. Eight vectorcardiographic parameters characterizing different aspects of ventricular repolarization were anal...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.05.004
更新日期：2010-07-01 00:00:00
abstract：:We present an example of sudden modification in QRS morphology during ventricular pacing inside a scar-related isthmus. This is explained by a "concealed" sudden block in both the orthodromic and antidromic wavefront directions, allowing then the activation to proceed through a now overt antidromic conduction. ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2016.07.035
更新日期：2016-01-01 00:00:00
abstract：:Direct Wenckebach periods in the left bundle branch with periods of 4:3 and 5:4 conduction alternating with 2:1 left bundle branch block (LBBB) were observed in a patient who was admitted because of congestive heart failure. There was no previous documented LBBB and serial electrocardiographic (ECG) mainfestations aft...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(80)80034-3
更新日期：1980-01-01 00:00:00
abstract：:One of the most important components of mechanoelectric coupling is stretch-activated channels, sarcolemmal channels that open upon mechanical stimuli. Uncovering the mechanisms by which stretch-activated channels contribute to ventricular arrhythmogenesis under a variety of pathologic conditions is hampered by the la...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2010.05.014
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Accurate measurement of QRS complex duration (QRSd) remains crucial for the selection of patients for cardiac resynchronization therapy (CRT). However, assessment of QRSd on conventional surface electrocardiograms (ECG), especially when performed without computer assistance, may be challenging due to the lim...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.08.011
更新日期：2019-01-01 00:00:00
abstract：:His bundle electrograms of 40 patients developing Wenckebach block during atrial pacing and four with spontaneous Wenckebach block above the His were reviewed to determine the frequency of classical Wenckebach periodicity. Thirty patients had 143 Wenckebach cycles that were suitable for analysis. Cycles were evaluated...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(75)80003-3
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation occurs in 20% to 40% of patients post cardiac surgery. Prophylactic amiodarone decreases the incidence of atrial fibrillation, especially in those not taking β-blockers. Studies, however, vary in dosage, duration of treatment, and route of administration. Limited studies evaluating short ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jelectrocard.2012.07.005
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation (AF) and ventricular arrhythmias (VAs) are associated with increased morbidity and mortality. However, data are lacking concerning the association of AF and VAs. This study aimed to clarify the association between AF and VAs and to investigate the effect of amiodarone on the incidence of ...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.jelectrocard.2018.10.083
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE:We investigated the correlation between the presence of hump sign during exercise tes...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.09.001
更新日期：2010-03-01 00:00:00
