Abstract：
AIM:To evaluate the diagnostic accuracy of electrocardiographic inferior Q waves persistence during inspiration and echocardiographic segmental wall motion abnormalities for the detection of previously unsuspected silent myocardial infarction, by using cardiac magnetic resonance as the gold standard. METHODS:We prospectively enrolled 50 apparently healthy subjects with inferior Q waves on routine electrocardiogram and high atherosclerotic risk profile. Patients underwent electrocardiogram during deep inspiration, standard transthoracic echocardiography, and cardiac magnetic resonance. RESULTS:Inferior Q waves during deep inspiration persisted in 10 subjects (20%) and cardiac magnetic resonance was positive in 10 (20%). Between the 10 positive cardiac magnetic resonance subjects 8 showed persistence of inferior Q waves, giving a sensitivity of 80% (95%;CI 44.4-97.5%) and a specificity of 95% (95%;CI 83.1-99.4%). Segmental wall motion abnormalities were present overall in 10 subjects (20%), but only in 5 of the 10 positive cardiac magnetic resonance subjects, giving a sensitivity of 87.5% (95% CI 73.2-95.8) and specificity of 50% (95% CI 18.7-81.3). CONCLUSIONS:Electrocardiographic inferior Q waves persistence during deep inspiration is a simple test with a high accuracy for diagnosis of silent myocardial infarction. Standard echocardiography resulted less accurate.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Nanni S,Lovato L,Vagnarelli F,Ghetti G,Ferlito M,Pasquale F,Russo V,Zompatori M,Bacchi Reggiani L,Semprini F,Taglieri N,Melandri G,Rapezzi Cdoi
10.1016/j.jelectrocard.2015.08.026subject
Has Abstractpub_date
2016-01-01 00:00:00pages
46-54issue
1eissn
0022-0736issn
1532-8430pii
S0022-0736(15)00275-7journal_volume
49pub_type
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