Abstract：
BACKGROUND:Periodic repolarization dynamics (PRD) refers to low-frequency oscillations of cardiac repolarization, most likely related to phasic sympathetic activation. Increased PRD is a validated predictor of mortality after myocardial infarction and in ischemic heart disease, but has not been tested in aortic valve stenosis (AS). Here, we assessed PRD in patients with AS and tested its correlation with clinical and hemodynamic parameters as well as markers of heart rate variability (HRV). MATERIALS AND METHODS:We prospectively enrolled 139 consecutive patients with moderate to severe AS in sinus rhythm. In all patients we performed a 24-h Holter ECG in Frank-leads configuration. We assessed PRD according to previously published technologies from the nocturnal hours (0am-6am) and dichotomized PRD at the established cut-off value of ≥5.75deg2. In addition to clinical and hemodynamic markers, we also assessed deceleration capacity (DC) of heart rate, heart rate turbulence and standard HRV parameters. RESULTS:In the patients studied, PRD was 6.55±3.96deg2. Seventy-three patients (52.5%) had increased PRD. Among them, 36 (49.9%) patients were classified as being asymptomatic. There was no association between increased PRD and clinical or hemodynamic markers, including presence of symptoms, NYHA-classification, aortic valve area, and left-ventricular ejection fraction. Thirty-three of the 73 (45.2%) patients with PRD ≥5.75deg2 also suffered from decreased vagal tonic activity by means of abnormal DC (≤2.5ms) indicating severe autonomic dysfunction. CONCLUSION:Prevalence of increased PRD is high among patients with moderate to severe AS. Patients with increased PRD cannot be identified by clinical or hemodynamic markers Future studies should test the prognostic value of PRD in patients with AS.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Rizas KD,Zuern CS,Bauer Adoi
10.1016/j.jelectrocard.2017.08.004subject
Has Abstractpub_date
2017-01-01 00:00:00pages
802-807issue
6eissn
0022-0736issn
1532-8430pii
S0022-0736(17)30244-3journal_volume
50pub_type
杂志文章abstract：:Two cases of transient hemiblock occurring during the course of acute myocardial infarction are reported. The transient manifestation permits the accurate evaluation of the diagnostic features of the hemiblocks as modified by acute infarction. One case reflects the development of left bundle branch block due to bilate...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(78)80109-5
更新日期：1978-04-01 00:00:00
abstract：:A 65-year old male originally presented with repetitive ventricular bigeminal sequences demonstrating progressive prolongation of successive coupling intervals suggesting Wenckeback-type exit block. An even number distribution of conducted beats always intervened between bigeminal sequences. Subsequent analysis proved...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(78)80146-0
更新日期：1978-10-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(82)80007-1
更新日期：1982-04-01 00:00:00
abstract：:Extensive experience has been obtained with Medtronic pacemakers, in Glasgow where over 400 patients have received their primary implant. In this review, which covers a period of seven and a half years ending December 31, 1973, the technical reliability of electrode-leads is considered in terms of failed implant lifet...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(75)80030-6
更新日期：1975-01-01 00:00:00
abstract：:The authors present an original method for the discrimination of patients prone to ventricular tachycardia. The wavelet transform, which is a new time-scale technique suitable for transient signal detection, was applied to bipolar unfiltered X, Y, Z signal-averaged electrocardiograms in 20 postinfarction patients with...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(93)90052-f
更新日期：1993-10-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Descriptions of the significance of ST segment or QRS abnormalities in myocarditis are limited because documentation of the diagnosis has previously required myocardial biopsy. Late gadolinium enhancement (LGE) and T2 weighted imaging in the midventricular wall on cardiac magnetic resonance imagi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2014.07.018
更新日期：2014-11-01 00:00:00
abstract：:VPC morphology was studied in the surface 12-leads ECGs (resting) in one hundred and thirty-six patients over a none-month period (January-September, 1978). Seventy four (54%) of these had coronary artery disease proven by cardiac catheterization (61) or by evidence of acute transmural myocardial infarction (13) diagn...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(80)80083-5
更新日期：1980-10-01 00:00:00
abstract：BACKGROUND:As technology infiltrates more of our personal and professional lives, user expectations for intuitive design have driven many consumer products, while medical equipment continues to have high training requirements. Not much is known about the usability and user experience associated with hospital monitoring...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.08.032
更新日期：2015-11-01 00:00:00
abstract：:A prolonged QT interval is an important prognostic indicator for cardiac arrhythmias and sudden death. The conventional QT interval measurement, however, includes in its measure the cardiac depolarization (QRS) as well as the cardiac repolarization (JT) intervals. To evaluate the relative contribution of the depolariz...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/0022-0736(90)90150-z
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Brugada syndrome (BrS) is an inherited ion channelopathy that may predispose affected individuals to atrial cardiomyopathy. We tested the hypothesis that BrS patients have higher degrees of atrial electrophysiological abnormalities compared to controls, and these can be reflected by changes in P-wave paramet...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.05.005
更新日期：2019-01-01 00:00:00
abstract：:Five male patients with chronic stable ventricular arrhythmias underwent a placebo controlled ascending dose study with oral cibenzoline, a new type 1 antiarrhythmic drug. Ambulatory ECG (Holter) recordings and electrophysiologic studies were done while on placebo and on the maximum dose of cibenzoline. Drug toxicity,...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0022-0736(84)80020-5
更新日期：1984-01-01 00:00:00
abstract：:No prior studies have evaluated the relationship between the site of right ventricular stimulation, the site of prior infarction, and the inducibility of ventricular tachycardia (VT). This study was performed to determine if the location of pathologic Q waves influences the inducibility of VT at various right ventricu...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(98)90012-7
更新日期：1998-10-01 00:00:00
abstract：:The electrocardiogram (ECG) is a relatively insensitive tool for the detection of right ventricular hypertrophy (RVH), but some criteria have high specificity. The recommended ECG screening criteria for RVH are not sufficiently sensitive or specific for screening for mild RVH in adults without clinical cardiovascular ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2017.09.004
更新日期：2018-01-01 00:00:00
abstract：:Electrocardiograms and His bundle electrograms were presented from a patient with a rare combination of intermittent bilateral bundle branch block. Critical analyses of R-R intervals and evolution of bundle branch block patterns revealed both tachycardia dependent right bundle branch block and bradycardia dependent le...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(81)80057-x
更新日期：1981-01-01 00:00:00
abstract：:In eighteen patients with atrioventricular conduction disturbance, His bundle electrograms were studied via the arm vein. A 6F Berkovits-Castellanos USCI hexapolar electrode catheter was introduced into the right atrium and looped across the tricuspid valve in a "golf club" shape. The main aim was to leave the two dis...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(81)80046-5
更新日期：1981-01-01 00:00:00
abstract：:A 63 year old man with angina pectoris was found to have frequent extrasystoles separated by odd as well as even numbers of conducted sinus beats. Analysis of 935 conducted sinus beats showed that premature ventricular beats without interpolation were separated by odd numbers of conducted sinus beats in 117 sequences ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(82)80033-2
更新日期：1982-01-01 00:00:00
abstract：:The Brugada syndrome (BS) accounts for approximately 20% of cases of sudden cardiac death in patients with structurally normal hearts. The electrophysiologic basis for ST-segment elevation in the precordial electrocardiogram (ECG) leads that characterize the Brugada phenotype and its strong linkage to ventricular tach...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.07.008
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:"Cardiac memory" (CM) refers to a change in repolarization induced by an altered pathway of activation, manifested after resumption of spontaneous ventricular activation (SVA). AIMS:To investigate for the first time in humans the effects of left ventricular (LV) pacing on CM development through vectorcard...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.05.007
更新日期：2015-07-01 00:00:00
abstract：:Ventricular fibrillation (VF) is the most common arrhythmia leading to sudden cardiac death, but in rare cases VF can manifest as a syncope, provided that it will self-terminate. We present a case of a 45-year old female with a history of unexplained syncopal episodes despite exhaustive diagnostics. Implantable loop r...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2018.04.006
更新日期：2018-01-01 00:00:00
abstract：:Severe bradyarrythmias remain as an important cause for hospital urgent admission and these patients can suffer potentially lethal complications (such as ventricular fibrillation [VF] and torsades de pointes [TdP]) between hospital admission and final therapy. Incidence and predictors of these tachyarrhythmias have no...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2003.10.003
更新日期：2004-01-01 00:00:00
abstract：:Junctional ectopic tachycardia(JET) is a rare childhood arrhythmia originating from the area adjacent to the atrioventricular(AV) node. It often occurs after surgical procedures like repair of Tetralogy of Fallot, atrioventricular septal defect and ventricular septal defect, which are all performed in that area. While...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.01.015
更新日期：2017-01-01 00:00:00
abstract：UNLABELLED:Cardiac function management devices, including implantable pacemakers and implantable defibrillators, include at least 1 cardiac lead having an electrode for making contact with a portion of the heart. It has been previously shown that the braided multifilament wire electrodes have a high failure rate both f...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.07.019
更新日期：2009-11-01 00:00:00
abstract：:A 58-year-old woman with a history of multi-origin atrial tachycardia and limb-girdle muscular dystrophy was treated for presyncope caused by pauses in atrial rhythm. A dual-chamber pacemaker was implanted. The low-voltage area extended broadly, but 10-V pacing could not capture the large right atrium, including the r...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2020.05.003
更新日期：2020-01-01 00:00:00
abstract：:We have analyzed the Wilson ventricular gradient in terms of body surface potential maps and of the reduction of such surface patterns to equivalent dipoles or vectors. While the ventricular gradient traditionally was treated as first a scalar, then a vector concept, we found that the three entities (QRS area, T area,...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(81)81013-8
更新日期：1981-10-01 00:00:00
abstract：:The Brugada syndrome is characterized by ST-segment elevation in the right precordial leads (V1 through V3) and an episode of ventricular fibrillation in the absence of structural heart disease. SCN5A, the gene encoding the alpha subunit of the sodium channel, is the only gene thus far linked to the Brugada syndrome b...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2005.06.005
更新日期：2005-10-01 00:00:00
abstract：:The addition of propranolol to mexiletine may reduce the adverse effects of mexiletine and possibly increase its efficacy. We compared the cellular electrophysiologic effects of this combination with mexiletine and propranolol alone, over concentration ranges of 3.2 to 100 microM mexiletine and 0.80 to 25.0 microM pro...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(87)80080-8
更新日期：1987-11-01 00:00:00
abstract：:Placement of the precordial electrodes for recording a 12-lead electrocardiogram (ECG) is subject to variation. Previous research has shown that displacement, especially in the longitudinal direction, can lead to changes in diagnosis. In practice, both the displacement and the effects of displacement on an individual ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(96)80002-1
更新日期：1996-01-01 00:00:00
abstract：:Time course evolution of R, Q, T and ST components of the electrocardiogram during the first 12 hours of an acute myocardial infarction was studied. A comparison between anterior-extensive and anteroseptal wall infarctions (anterior group), and inferior-extensive and inferior wall infarction (inferior group) showed ap...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(87)80098-5
更新日期：1987-04-01 00:00:00
abstract：:Sources of error in averaging for late ventricular potentials include variations in the magnitude and timing of late potentials as well as variability in the temporal alignment of successive cardiac cycles during averaging. Since these errors can both attenuate high frequency signals and add artifactual components to ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:The electrophysiologic actions of epinephrine (10(-9) M, 10(-8) M, and 10(-7) M) were evaluated in canine Purkinje fibers pretreated with the class III antiarrhythmic drugs clofilium (10(-7) M) or d,l-sotalol (10(-6) M). Clofilium and d,l-sotalol prolonged action potential duration at 50% and 90% of repolarization wit...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(97)80007-6
更新日期：1997-07-01 00:00:00
