Abstract:
:Microbeam facilities provide a unique opportunity to investigate the effects of ionising radiation on living biological cells with a precise control of the delivered dose. This paper describes dosimetry calculations performed at the single-cell level in the microbeam irradiation facility available at the Centre d'Etudes Nucléaires de Bordeaux-Gradignan in France, using the object-oriented Geant4 Monte Carlo simulation toolkit. The cell geometry model is based on high-resolution three-dimensional voxelised phantoms of a human keratinocyte (HaCaT) cell line. Such phantoms are built from confocal microscopy imaging and from ion beam chemical elemental analysis. Results are presented for single-cell irradiation with 3 MeV incident alpha particles.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Incerti S,Seznec H,Simon M,Barberet P,Habchi C,Moretto Pdoi
10.1093/rpd/ncp003subject
Has Abstractpub_date
2009-01-01 00:00:00pages
2-11issue
1eissn
0144-8420issn
1742-3406pii
ncp003journal_volume
133pub_type
杂志文章abstract::Fluorescent in situ hybridisation analysis of stable translocations was performed for 26 residents living along the Techa River (Russia), who were predominantly (95%) exposed to ingested strontium radioisotopes ((89)Sr and (90)Sr) resulting in exposure of their red bone marrow (RBM). Analysis was conducted at the Ural...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncu131
更新日期:2014-06-01 00:00:00
abstract::A water-filled tissue equivalent phantom with a diameter of 35 cm was developed at the Institute for Biomedical Problems. Moscow. Russia. It contains four channels perpendicular to each other, where dosemeters can be exposed at different depths. Between May 1997 and February 1999 the phantom was installed at three dif...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a005923
更新日期:2002-01-01 00:00:00
abstract::To measure dose distribution for X- and gamma rays simply and accurately, a tissue-equivalent thermoluminescent (TL) sheet-type dosemeter and reader system were developed. The TL sheet is composed of LiF:Mg,Cu,P and ETFE polymer, and the thickness is 0.2 mm. For the TL reading, a square heating plate, 20 cm on each si...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci571
更新日期:2006-01-01 00:00:00
abstract::The material for this study comprised control protocols from 248 mammography screening facilities, prepared by physicists employed at 16 Regional Coordinating Centres and the results from the clinical evaluation of mammographic images in 248 facilities in Poland. All mammograms were evaluated independently by three ex...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,多中心研究
doi:10.1093/rpd/ncr321
更新日期:2011-09-01 00:00:00
abstract::The frequencies and effective doses for the most common X-ray diagnostic examinations in Ukraine were assessed in the frame of the European Commission (EC) Study on European Population Doses from Medical Exposure (Dose Datamed 2). The average effective doses for all radiographic procedures were estimated using the ODS...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv121
更新日期:2015-07-01 00:00:00
abstract::Electron paramagnetic resonance spectra and dose-response curves are presented for a variety of wallboard samples obtained from different manufacturing facilities, as well as for source gypsum and anhydrite. The intensity of the CO(3)(-) paramagnetic centre (G2) is enhanced with gamma radiation. Isothermal decay curve...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq581
更新日期:2011-11-01 00:00:00
abstract::This paper describes the design and construction of a new performance testing programme that was implemented in Canada in 2008. The Canadian Regulator (Canadian Nuclear Safety Commission) had determined that their licensees, in addition to participating in the existing in vivo and in vitro performance tests, needed to...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp088
更新日期:2009-06-01 00:00:00
abstract::At a high-energy, high-intensity proton accelerator facility, the accelerator components inside the beam-line tunnel and the concrete wall of the tunnel are activated due to beam loss during operation. During maintenance work inside the tunnel, radiation emitted from these activated materials can cause exposure to rad...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl475
更新日期:2007-01-01 00:00:00
abstract::Lignite burning is one of the sources of technologically enhanced exposure to humans from natural radionuclides. In the preliminary study, part of the survey, the activity concentrations of (226)Ra, (232)Th and (40)K in 112 samples of feed lignites from seven lignite-fired power plants in Western Anatolia (Seyitömer, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq210
更新日期:2010-12-01 00:00:00
abstract::In radiotherapy, radiochromic films can be used for verification of delivery of dose distributions calculated by treatment planning systems. The main objective of this work was to compare three different techniques for evaluation of dose distributions for prostate cancer treatment plans using radiochromic EBT3 films. ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz231
更新日期:2019-12-31 00:00:00
abstract::Virtual models of real phantoms used with Monte Carlo methods facilitate the calibration and other studies associated with whole-body and partial-body counting systems. In this investigation, a voxel model of an LLNL torso phantom, available physically in the in vivo laboratory at KIT, was created from computed tomogr...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp030
更新日期:2009-02-01 00:00:00
abstract::The reliability of equivalent-dose determinations on quartz made with the single-aliquot regenerative-dose (SAR) protocol is examined using a suite of sedimentary samples for which the equivalent dose is expected to be >200 Gy. Experiments on one sample were used to evaluate the precision obtained using the standard m...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006004
更新日期:2002-01-01 00:00:00
abstract::Amongst the dosemeters offered by the Health Protection Agency (HPA) Personal Dosimetry Service are finger rings, which use the Harshaw™ DXTRAD element. This paper describes restricted-type testing carried out by HPA on the previously untried combination of the LiF:Mg,Cu,P material and a thicker filter (42 mg cm(-2))....
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq564
更新日期:2011-03-01 00:00:00
abstract::A secondary standard ionisation chamber for photon radiation for measuring an ionisation current, which is directly proportional to the conventionally true value of the ambient dose equivalent, H*(10), was optimised. The chamber was developed in the Austrian Research Centers Seibersdorf and is used successfully worldw...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci334
更新日期:2006-01-01 00:00:00
abstract::The focus of nuclear emergency planning in Austria has been so far on mitigating effects of widespread contamination (e.g. after NPP accidents); however, these plans did not contain provisions on the medical management of an acute radiation syndrome. To close this gap, a 'Medical Radiation Emergency Plan' was created ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw210
更新日期:2016-09-01 00:00:00
abstract::Various radionuclides are used in nuclear medicine in different diagnostic and therapeutic procedures. Recently, interest has grown in therapeutic agents for some interesting applications in nuclear medicine. Internal dose models and methods in use for many years are well established, and can give radiation doses to s...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,评审
doi:10.1093/oxfordjournals.rpd.a006306
更新日期:2003-01-01 00:00:00
abstract::Ionising radiation exposure of cells might induce the perturbation of cell functions and, in particular, the activation or inhibition of several important pathways. This perturbation can cause the deregulation of both intra- and extra-cellular signalling cascades (such as the inflammatory pathway) and alter not only t...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv132
更新日期:2015-09-01 00:00:00
abstract::Neutron emission rate measurements have been carried out at the Korea Research Institute of Standards and Science using a manganese sulphate bath system for (252)Cf and (241)Am-Be sources since 2004. The relative measurement method was chosen in 2012, and the neutron emission rates agreed with those by the absolute me...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct327
更新日期:2014-10-01 00:00:00
abstract::Regarding in vivo L-band dosimetry with human teeth, a number of preliminary experiments were carried out that were linked to the resonators response and the relative contribution of enamel to the EPR signal intensity of irradiated whole teeth. The sensitivity of the extended loop resonator varies in the antenna plane...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006036
更新日期:2002-01-01 00:00:00
abstract::The rigorous characterisation of the behaviour of a radiobase antenna for wireless communication systems is a hot topic both for antenna or communication system design and for radioprotection-hazard reasons. Such a characterisation deserves a numerical solution, and the use of a finite-difference time-domain (FD-TD) a...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006699
更新日期:2001-01-01 00:00:00
abstract::This paper describes the findings of the radiation situation analysis on-site near Sysoeva and Razbojnik Bays. The results of radiation monitoring performed by radiological laboratory of DalRAO and studies performed by the experts from the Burnasyan Federal Medical Biophysical Centre have been used in the course of an...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr135
更新日期:2011-07-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch432
更新日期:2005-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章,多中心研究
doi:10.1093/rpd/ncy123
更新日期:2019-05-01 00:00:00
abstract::In this study, radioactivity levels of 35 different samples of 11 commonly used building materials in Samsun were measured by using a gamma spectrometry system. The analysis carried out with the high purity Germanium gamma spectrometry system. Radioactivity concentrations of (226)Ra, (232)Th and (40)K range from 6 to ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct047
更新日期:2013-01-01 00:00:00
abstract::In 2008, the German Childhood Cancer Registry published the results of the Kinderkrebs in der Umgebung von Kernkraftwerken (KiKK) study of childhood cancer and leukaemia around German nuclear power stations. The positive findings appeared to conflict with the results of a recent British analysis carried out by the Com...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,评审
doi:10.1093/rpd/ncn254
更新日期:2008-01-01 00:00:00
abstract::Results of field tests with explosive dispersal of a radioactive substance (RaS) are presented. The paper deals with tests exploiting artificial obstacles as a continuation and expansion of the tests used in this study performed in free area described previously. The essential goal of the tests was to estimate the dis...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncs209
更新日期:2013-04-01 00:00:00
abstract::In this article, an approach to compute the dose conversion coefficients (DCCs) is described for the computational voxel phantom 'High-Definition Reference Korean-Man' (HDRK-Man) using artificial neural networks (ANN). For this purpose, the voxel phantom was implemented into the Monte Carlo (MC) transport toolkit GEAN...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv436
更新日期:2016-12-01 00:00:00
abstract::A small, specialised amplifier using commercial integrated circuits (ICs) was developed to measure radiation dose and quality in real time using a microdosimetric ion chamber and the variance method. The charges from a microdosimetric ion chamber, operated in the current mode, were repeatedly collected for a fixed per...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm231
更新日期:2008-01-01 00:00:00
abstract::Computed tomography dose index w and dose length product were recorded for the purpose of developing diagnostic reference levels (DRLs) for radiation dose optimisation. The study was conducted in three radiology departments with CT centres in Northern Nigeria. Data were collected from 54 consenting adult participants ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,多中心研究
doi:10.1093/rpd/ncv188
更新日期:2015-07-01 00:00:00
abstract::A sample is provided of the radiological safety issues particular to low energy proton accelerators. 'Low' energy in this context is taken to mean proton energies of less than about 1 GeV. Many of the radiation issues are common to all particle accelerators. Here, those issues are addressed that may require perhaps no...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,评审
doi:10.1093/oxfordjournals.rpd.a006619
更新日期:2001-01-01 00:00:00