Molecular dynamics study of the interaction between fatty acid binding proteins with palmitate mini-micelles.

abstract：:We examined the Hepatitis C virus (HCV) genome in the myocardium and liver obtained at autopsy from seven patients with HCV-positive liver cirrhosis and hepatocellular carcinoma (HCC) by in situ hybridization and histopathological studies. The HCV virus genome was detected in the myocardium of one patient as well as i...

journal_title：Molecular and cellular biochemistry

authors： Takeda A,Sakata A,Takeda N

更新日期：1999-05-01 00:00:00

abstract：:Hydrogen sulfide (H2S) has been investigated widely in recent years. H2S plays a variety of roles in different biological systems, including cardiovascular system. It is the final product of amino acids metabolism, which contains sulfur-cysteine and homocysteine (Hcy). In human plasma, there are several various forms ...

journal_title：Molecular and cellular biochemistry

authors： Olas B,Kontek B

更新日期：2015-06-01 00:00:00

abstract：:β-Adrenergic receptor (β-AR) stimulation induces cardiac myocyte apoptosis and plays an important role in myocardial remodeling. Here we investigated expression of various apoptosis-related genes affected by β-AR stimulation, and examined first time the role of ataxia telangiectasia mutated kinase (ATM) in cardiac myo...

journal_title：Molecular and cellular biochemistry

authors： Foster CR,Singh M,Subramanian V,Singh K

更新日期：2011-07-01 00:00:00

abstract：:Cyclophosphamide (CP), an alkylating agent widely used in cancer chemotherapy causes cardiac membrane damage. Lupeol, a pentacyclic triterpene, isolated from Crataeva nurvala stem bark and its ester, lupeol linoleate possess a wide range of medicinal properties. The effect of lupeol and its ester was evaluated in CP i...

journal_title：Molecular and cellular biochemistry

authors： Sudharsan PT,Mythili Y,Selvakumar E,Varalakshmi P

更新日期：2006-11-01 00:00:00

abstract：:Pancreatic islet cytosol contains a calcium-calmodulin dependent protein kinase that can mediate the phosphorylation of an endogenous protein that has an Mr of 57 000, as well as exogenous muscle pyruvate kinase (subunit Mr, 57 000). EGTA and trifluoperazine decreased the phosphorylation. Alkaline inactivation of pyru...

journal_title：Molecular and cellular biochemistry

authors： MacDonald MJ,Kowluru A

更新日期：1985-10-01 00:00:00

abstract：:The collagen metabolism alterations triggered by reactive oxygen species are involved in the development of various connective tissue diseases and skin aging. This study was designed to examine whether (E)-anethole possesses a protective effect on H2O2-induced alterations in collagen metabolism as well as whether it c...

journal_title：Molecular and cellular biochemistry

authors： Galicka A,Krętowski R,Nazaruk J,Cechowska-Pasko M

更新日期：2014-09-01 00:00:00

abstract：:Prolonged ischemia-reperfusion results in various damages in skeletal muscle. Following reperfusion, although the damaged muscles undergo regeneration, the precise process and mechanism of regeneration have not yet been fully understood. Here, we show the altered levels of plasma biochemical markers of muscle damage, ...

journal_title：Molecular and cellular biochemistry

authors： Itoh M,Shimokawa N,Tajika Y,Murakami T,Aotsuka N,Lesmana R,Farenia R,Iwasaki T,Okda J,Yorifuji H,Koibuchi N

更新日期：2013-01-01 00:00:00

abstract：:Apoptosis-inducing agents have been reported to cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1) in endothelial cells (EC). Oxidized LDL (oxLDL) has also been known to induce apoptosis of EC and to inhibit proliferation of EC. In the present study, we show that oxLDL also causes shedding of TNFR1 in EC...

journal_title：Molecular and cellular biochemistry

authors： Sugano M,Tsuchida K,Makino N

更新日期：2004-03-01 00:00:00

abstract：:Obesity-induced low-grade inflammation (metaflammation) impairs insulin receptor signaling. This has been implicated in the development of insulin resistance. Insulin signaling in the target tissues is mediated by stress kinases such as p38 mitogen-activated protein kinase, c-Jun NH2-terminal kinase, inhibitor of NF-k...

journal_title：Molecular and cellular biochemistry

authors： Nandipati KC,Subramanian S,Agrawal DK

更新日期：2017-02-01 00:00:00

abstract：:Muscle injury is a common result of muscle exertion caused by overload and over-activity. In this presentation, an attempt was made to discuss models of muscle injury which involve exertion but not excessive strain, although most functional activities of the extremities require some eccentric muscle actions. Muscle in...

journal_title：Molecular and cellular biochemistry

authors： Stauber WT,Smith CA

更新日期：1998-02-01 00:00:00

abstract：:In order to compare the role of the Ca(2+)-receptive protein (troponin), in the characteristic myofibrillar contractile response of chicken fast and slow skeletal muscles, the troponin in both kinds of myofibrils were partially exchanged, under slightly acidic conditions. The Ca(2+)- or Sr(2+)-activation of the ATPase...

journal_title：Molecular and cellular biochemistry

authors： Kawashima A,Shiraishi F,Ohtsuki I,Yamamoto K

更新日期：1994-03-30 00:00:00

abstract：:Logistic complexities of heart transplantation embossed the necessity of utilizing novel methods, which enable heart regeneration. Human cardiosphere-derived cells (hCDCs) are taken into consideration as a promising cell resource in cell therapy in recent years. In this study, we designed an electrochemical stimulatio...

journal_title：Molecular and cellular biochemistry

authors： Nazari H,Kehtari M,Rad I,Ashtari B,Joghataei MT

更新日期：2020-07-01 00:00:00

abstract：:A method for non-invasive, quantitative 31P NMR spectroscopic investigation of mitochondrial function in human skeletal muscle in situ is described. High time resolution 31P NMR measurements of phosphocreatine, inorganic phosphate and ATP resonances were conducted on human forearm flexor muscle during involuntary twit...

journal_title：Molecular and cellular biochemistry

authors： Jeneson JA,Wiseman RW,Kushmerick MJ

更新日期：1997-09-01 00:00:00

abstract：:The results of our previous studies demonstrated that acute streptozotocin-induced diabetes in rats evoked a decrease in skin collagen content with little effect on glycosaminoglycans (GAG) content. In our present study we employed the model of chronic diabetes in order to check its effect on skin GAG content. It was ...

journal_title：Molecular and cellular biochemistry

authors： Cechowska-Pasko M,Pałka J,Bańkowski E

更新日期：1996-01-12 00:00:00

abstract：:A sialic acid binding lectin, AchatininH, was purified in single step from the hemolymph of the land snail, Achatina fulica, by the affinity chromatography on sheep submaxillary mucin coupled to Sepharose 4B. The yield of the lectin was found to be 3 mg from 100 ml of hemolymph. The homogeneity of the lectin was estab...

journal_title：Molecular and cellular biochemistry

authors： Basu S,Sarkar M,Mandal C

更新日期：1986-08-01 00:00:00

abstract：:A number of quite specific and fairly potent inhibitors of protein kinase CK2, belonging to the classes of condensed polyphenolic compounds, tetrabromobenzimidazole/triazole derivatives and indoloquinazolines are available to date. The structural basis for their selectivity is provided by a hydrophobic pocket adjacent...

journal_title：Molecular and cellular biochemistry

authors： Sarno S,Ruzzene M,Frascella P,Pagano MA,Meggio F,Zambon A,Mazzorana M,Di Maira G,Lucchini V,Pinna LA

更新日期：2005-06-01 00:00:00

abstract：:Resveratrol (trans-3,5,4'-trihydroxystilbene), a compound found largely in the skins of red grapes and wines, possesses anti-cancer and anti-angiogenic properties and protects the cardiovascular system. However, the molecular mechanisms by which resveratrol inhibits angiogenesis are currently subjects of intense inves...

journal_title：Molecular and cellular biochemistry

authors： Srivastava RK,Unterman TG,Shankar S

更新日期：2010-04-01 00:00:00

abstract：:We have focused on the roles of PARP and poly(ADP-ribosyl)ation early in apoptosis, as well as during the early stages of differentiation-linked DNA replication. In both nuclear processes, a transient burst of PAR synthesis and PARP expression occurs early, prior to internucleosomal DNA cleavage before commitment to a...

journal_title：Molecular and cellular biochemistry

authors： Simbulan-Rosenthal CM,Rosenthal DS,Iyer S,Boulares H,Smulson ME

更新日期：1999-03-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is one of the rare cancers in western countries but predominant in Southeast Asian countries including Thailand. One major cause for failure of NPC chemotherapeutic treatments is reportedly correlated with the elevation of cancer stem cell (CSC) fractions. Thus, this present study aims t...

journal_title：Molecular and cellular biochemistry

authors： Sinnung S,Janvilisri T,Kiatwuthinon P

更新日期：2021-01-09 00:00:00

abstract：:The objective of the present study was to compare energy substrate fluxes through metabolic pathways leading to mitochondrial citrate synthesis and release in normal and diseased rat hearts using 13C-substrates and mass isotopomer analysis by gas chromatography-mass spectrometry (GCMS). This study was prompted by our ...

journal_title：Molecular and cellular biochemistry

authors： Vincent G,Khairallah M,Bouchard B,Des Rosiers C

更新日期：2003-01-01 00:00:00

abstract：:Atherosclerosis is the leading cause of death in North America. It is characterized by thickening of the coronary artery wall by the formation of plaques, resulting in reduced blood flow. Plaque rupture and the consequent thrombosis may lead to sudden blockage of arteries and causing stroke and heart attack. In the la...

journal_title：Molecular and cellular biochemistry

authors： Choy PC,Mymin D,Zhu Q,Dakshinamurti K,O K

更新日期：2000-04-01 00:00:00

abstract：:Our interest in the role of sulfhydryl groups (SH) in regulating or altering transport across biological membranes has focused on the significance of a critical SH group associated with the Ca2+-release protein from skeletal muscle sarcoplasmic reticulum (SR). We have shown that binding of heavy metals to this group o...

journal_title：Molecular and cellular biochemistry

authors： Abramson JJ,Salama G

更新日期：1988-07-01 00:00:00

abstract：:The homeodomain-containing Msx3 gene, the newest member of the Msx family, encodes two mRNAs, with an unknown relationship to each other. To elucidate how Msx3 gene generates the two transcripts, we cloned their corresponding cDNAs from an E10.5 mouse embryo cDNA library. The alignment of sequences of the two Msx3-spe...

journal_title：Molecular and cellular biochemistry

authors： Matsui H,Takahashi T,Raghow R

更新日期：2004-12-01 00:00:00

abstract：:A crude preparation of heavy sarcoplasmic reticulum (HSR) was isolated using 1 gram of muscle obtained from swine susceptible to malignant hyperthermia (MH) and from control swine. The caffeine and ATP concentration-dependency of Ca-release was determined using suction filtration with radioisotopic 45Ca as a tracer. R...

journal_title：Molecular and cellular biochemistry

authors： O'Brien PJ

更新日期：1990-03-05 00:00:00

abstract：:Elevated levels of triglycerides and very low density lipoproteins (VLDL) are biochemical markers of metabolic syndrome and diabetes. VLDL from hypertriglyceridemic or diabetic patients increased the generation of plasminogen activator inhibitor-1 (PAI-1) from cultured vascular endothelial cells (EC). Susceptibility o...

journal_title：Molecular and cellular biochemistry

authors： Zhao R,Ma X,Shen GX

更新日期：2008-10-01 00:00:00

abstract：:MicroRNAs play critical roles in the development and progression of non-small cell lung cancer (NSCLC). miR-96 acts as an oncogene in some malignancies, while its role in NSCLC is unclear. Here, we validated that miR-96 was significantly increased in both human NSCLC tissues and cell lines. Inhibition of miR-96 expres...

journal_title：Molecular and cellular biochemistry

authors： Guo H,Li Q,Li W,Zheng T,Zhao S,Liu Z

更新日期：2014-05-01 00:00:00

abstract：:Syndecan-4 (S4) is a cell membrane heparan sulfate proteoglycan that plays a role in satellite cell mediated myogenesis. S4 modulates the proliferation of myogenic satellite cells, but the mechanism of how S4 functions during myogenesis is not well understood. In other cell systems, S4 has been shown to form oligomers...

journal_title：Molecular and cellular biochemistry

authors： Shin J,Song Y,McFarland DC,Velleman SG

更新日期：2012-04-01 00:00:00

abstract：:Glycosphingolipid biosynthesis was examined using [3H]-galactose as a precursor as rat L6 myoblasts fused to form multinucleated myotubes. Incorporation of label into neutral glycolipids decreased steadily as the population of myotubes increased, so that final biosynthesis was one-half that observed with myoblasts (p ...

journal_title：Molecular and cellular biochemistry

authors： Leskawa KC,Erwin RE,Buse PE,Hogan EL

更新日期：1988-09-01 00:00:00

abstract：:Oxidation of semiquinone by O2 in the Q cycle is known to be one of the sources of superoxide anion (O2.-) in aerobic cells. In this paper, such a phenomenon was analyzed using the chemical kinetics model of electron transfer from succinate to cytochrome c, including coenzyme Q, the complex III non-heme iron protein F...

journal_title：Molecular and cellular biochemistry

authors： Demin OV,Kholodenko BN,Skulachev VP

更新日期：1998-07-01 00:00:00

abstract：:Development and repair of the skeletal system and other organs are highly dependent on precise regulation of the bone morphogenetic protein (BMP) pathway. The use of BMPs clinically to induce bone formation has been limited in part by the requirement of much higher doses of recombinant proteins in primates than were n...

journal_title：Molecular and cellular biochemistry

authors： Sangadala S,Yoshioka K,Enyo Y,Liu Y,Titus L,Boden SD

更新日期：2014-01-01 00:00:00