Transdermal oxygen delivery to diabetic wounds: a report of 6 cases.

Abstract:

OBJECTIVE:To evaluate the use of a transdermal sustained oxygen delivery system to promote the healing of chronic lower extremity wounds in patients with diabetes. METHODS:Six patients (5 men, 1 woman; age range, 32-77 years) with diabetes and chronic lower extremity wounds unresponsive to previous multimodal therapy were treated with transdermal sustained oxygen. The transdermal sustained oxygen delivery device (EpiFLO; Ogenix Corp, Cleveland, Ohio) delivered 100% oxygen at 3 mL/h with ambient humidity, 24 h/day, directly to the wound site, which was covered by an occlusive dressing. RESULTS:Despite chronicity of wounds (aged 4 months to >15 years) and nonresponsiveness to previous treatments, all wounds in this case series treated with transdermal sustained oxygen therapy improved within 2 to 20 weeks, within which time 5 of the 6 wounds had healed completely. In 2 cases, scheduled amputations were prevented. CONCLUSION:The results of the 6 cases reported here strongly support the use of transdermal sustained oxygen therapy in promoting the healing of diabetic foot and leg ulcers refractory to previous treatments. In addition, amputation was prevented in 2 cases, thus reducing prolonged costly patient care.

journal_name

Adv Skin Wound Care

authors

Hirsh F,Berlin SJ,Holtz A

doi

10.1097/01.ASW.0000343722.22943.40

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

20-4

issue

1

eissn

1527-7941

issn

1538-8654

pii

00129334-200901000-00008

journal_volume

22

pub_type

杂志文章,评审
  • Care of the laparoscopic colectomy patient.

    abstract::Laparoscopic bowel surgery has demonstrated patient care benefits of decreased duration of hospital stay, smaller incisions, lower risk of cardiopulmonary complications, and reduced risk of small-bowel obstruction. Resection of complicated diverticular disease and inflammatory bowel disease can be technically challeng...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/00129334-200211000-00009

    authors: Senagore AJ,Erwin-Toth P

    更新日期:2002-11-01 00:00:00

  • The relationship between hemoglobin A(1c) values and healing time for lower extremity ulcers in individuals with diabetes.

    abstract:PROBLEM:The diabetic population is at an increased risk, up to 15% over a lifetime, to develop leg and foot ulcers due to such factors as neuropathy, ischemia, and infection. The tight control of glucose levels as possible is necessary to prevent the diabetic complications by preventing microvascular changes that predi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000358639.45784.cd

    authors: Markuson M,Hanson D,Anderson J,Langemo D,Hunter S,Thompson P,Paulson R,Rustvang D

    更新日期:2009-08-01 00:00:00

  • Proxy study on minimizing risk of sacral pressure ulcers while complying with ventilator-associated pneumonia risk reduction guidelines.

    abstract::Bed positioning poses a subtle, yet important, tradeoff in the competing needs of hospitalized patients, particularly those susceptible to lower respiratory tract infections and/or pressure ulcers. Although it is widely held that a minimum 30° incline is necessary to mitigate risk of ventilator-acquired pneumonia, it ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000471877.19459.85

    authors: Crane BA,Wininger M,Kunsman M

    更新日期:2015-12-01 00:00:00

  • Epidermal micrografts produced via an automated and minimally invasive tool form at the dermal/epidermal junction and contain proliferative cells that secrete wound healing growth factors.

    abstract:OBJECTIVE:The aim of this scientific study was to assess epidermal micrografts for formation at the dermal-epidermal (DE) junction, cellular outgrowth, and growth factor secretion. Epidermal harvesting is an autologous option that removes only the superficial epidermal layer of the skin, considerably limiting donor sit...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000470024.81711.b8

    authors: Osborne SN,Schmidt MA,Derrick K,Harper JR

    更新日期:2015-09-01 00:00:00

  • High-Voltage Electrical Stimulation Versus Ultrasound in the Treatment of Pressure Ulcers.

    abstract:OBJECTIVE:The aim of this study was to assess and compare the efficacy of high-voltage electrical stimulation (HVES) with ultrasound (US) in treating Stage II through Stage IV pressure ulcers (PrUs)* of hospitalized patients. DESIGN:This study was designed as a prospective, controlled trial in which patients were rand...

    journal_title:Advances in skin & wound care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000526606.72489.99

    authors: Bora Karsli P,Gurcay E,Karaahmet OZ,Cakci A

    更新日期:2017-12-01 00:00:00

  • The 1999 National Pressure Ulcer Prevalence Survey: a benchmarking approach.

    abstract:OBJECTIVE:Health care professionals are faced with the ongoing challenge of improving performance. From physicians and nurses to process improvement experts, health care professionals are discovering new approaches to increasing the overall effectiveness of procedures used in clinical areas. One way to collect data use...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/00129334-200111000-00012

    authors: Amlung SR,Miller WL,Bosley LM

    更新日期:2001-11-01 00:00:00

  • Health-related quality of life in venous leg ulcer patients successfully treated with Apligraf: a pilot study.

    abstract::Apligraf (Graftskin) is a bilayered, living human skin construct that is indicated for use with standard therapeutic compression for the treatment of noninfected partial- and full-thickness skin ulcers due to venous insufficiency of greater than 1-month duration that have not adequately responded to conventional ulcer...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:

    authors: Mathias SD,Prebil LA,Boyko WL,Fastenau J

    更新日期:2000-03-01 00:00:00

  • Optimizing the Moisture Management Tightrope with Wound Bed Preparation 2015©.

    abstract:PURPOSE:To provide an overview of moisture management and its importance in wound care. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able t...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000470851.27030.98

    authors: Sibbald RG,Elliott JA,Ayello EA,Somayaji R

    更新日期:2015-10-01 00:00:00

  • Wound Healing Studies Using Punica granatum Peel: An Animal Experimental Study.

    abstract:OBJECTIVE:The goal of the present study was to evaluate the effects of hydroalcoholic extract-based carboxy methyl cellulose (CMC) gel of Punica granatum peel (PCMC) and CMC on healing of full-thickness skin wounds. MATERIALS AND METHODS:Forty-two rats were studied. Each rat had 3 wounds that were treated topically wi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000481116.16998.55

    authors: Zekavat O,Amanat A,Karami M,Paydar S,Gramizadeh B,Zareian-Jahromi M

    更新日期:2016-05-01 00:00:00

  • What is the best method for assessing the rate of wound healing? A comparison of 3 mathematical formulas.

    abstract:OBJECTIVE:To identify and evaluate current mathematical formulas used to assess the rate of wound healing. DATA SOURCES:MEDLINE, CINAHL, and Cochrane Systematic Review databases, from 1965 to 2004. STUDY SELECTION:Papers selected for the study met the following inclusion criteria: (1) participants had chronic venous,...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/00129334-200604000-00009

    authors: Jessup RL

    更新日期:2006-04-01 00:00:00

  • Treatment options for venous leg ulcers: effectiveness of vascular surgery, bioengineered tissue, and electrical stimulation.

    abstract:OBJECTIVE:To evaluate the peer-reviewed literature that compares advanced venous leg ulcer therapies to standard of care with compression dressings. METHODS:A MEDLINE search for venous ulcer treatment with electrical stimulation, surgical vein correction, and bioengineered tissues was conducted. Randomized clinical tr...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000462328.60670.c3

    authors: Thakral G,La Fontaine J,Kim P,Najafi B,Nichols A,Lavery LA

    更新日期:2015-04-01 00:00:00

  • Construction and Validation of an Instrument for Assessing the Feet of Persons with Diabetes.

    abstract:OBJECTIVE:To construct and validate an assessment instrument to evaluate the feet of people with diabetes mellitus in Brazil. METHODS:Methodological research developed in three stages: construction of the Assessment Instrument for the Feet of People with Diabetes Mellitus, validation of face and content validity, and ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000658588.28614.96

    authors: da Costa SP,Chavaglia SRR,Ohl RIB,Costa BY,Barbosa MH,Woo K,Gamba MA

    更新日期:2020-05-01 00:00:00

  • Development of a Nutrition Screening Tool for an Outpatient Wound Center.

    abstract:OBJECTIVE:To construct a quickly and easily administered nutrition screening tool using variables believed to be predictive of malnutrition risk in the wound patient population. DESIGN:A prospective pilot study assessed patients on a list of suspected variables, as well as the Scored Patient-Generated Subjective Globa...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000479803.09658.cb

    authors: Fulton J,Evans B,Miller S,Blasiole KN,Leone R,Beinlich N,Meehan A,Loose C

    更新日期:2016-03-01 00:00:00

  • The cost of illness of pressure ulcers in The Netherlands.

    abstract:OBJECTIVE:To conduct a cost-of-illness study of pressure ulcers in the Netherlands for different care settings, including home care, nursing homes, general hospitals, and university hospitals. DESIGN:A cost-of-illness study was conducted based on prevalence figures and expert opinion. A differential cost study approac...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/00129334-200203000-00008

    authors: Severens JL,Habraken JM,Duivenvoorden S,Frederiks CM

    更新日期:2002-03-01 00:00:00

  • An Introduction to Skin as an Interface: Implications for Interprofessional Collaboration and Whole-Person Care.

    abstract:GENERAL PURPOSE:To increase health care professionals' awareness and perceptions of the skin as one of the largest body organs with multidimensional aspects and significant implications for interprofessional collaboration in whole-person care. TARGET AUDIENCE:This continuing education activity is intended for physicia...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000557830.01516.6b

    authors: Sherman DW,Kamel G

    更新日期:2019-06-01 00:00:00

  • Cultured keratinocytes on urinary bladder matrix scaffolds increase angiogenesis and help in rapid healing of wounds.

    abstract:INTRODUCTION:Urinary Bladder Matrix (UBM) is an extracellular matrix (ECM) scaffold. It is now used in wound care management of partial and full-thickness wounds where conventional methods for wound care usually fail to give satisfactory results. OBJECTIVE:In this study, the authors are comparing the healing of full-t...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000398665.51283.44

    authors: Eweida A,Saad M,Gabr E,Marei M,Khalil MR

    更新日期:2011-06-01 00:00:00

  • Role of Vacuum-Assisted Closure in the Management of Crohn Anal Fistulas.

    abstract:BACKGROUND:Patients with Crohn disease-related anal fistulas are treated with debridement of fistulous tracts and the placement of noncutting setons (NCSs). However, to reduce the high recurrence rate, there is still a need to develop more effective treatment methods. OBJECTIVE:To compare NCS with vacuum-assisted clos...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000547411.16017.58

    authors: Hermann J,Banasiewicz T,Kołodziejczak B

    更新日期:2019-01-01 00:00:00

  • Adapted Crusting Technique in Children with Peristomal Lesions: A Case Series.

    abstract:OBJECTIVE:To describe the care of pediatric patients who had a gastrostomy and developed peristomal lesions and received a systematic single adapted crusting technique in a pediatric ICU in a tertiary Brazilian hospital. METHODS:An analysis of six cases presenting traumatic, noninfectious peristomal lesions with ostiu...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000661788.68292.81

    authors: Santos Monteiro AC,Barbosa Maia Dos Santos ML,Souza MA,Caires de Oliveira Achili Ferreira J

    更新日期:2020-06-01 00:00:00

  • Smoking Is a Risk Factor for Wound Complications after Direct Anterior Hip Arthroplasty with Mesh Tape Closure.

    abstract:OBJECTIVE:To determine what factors increase the risk of early wound complications in patients undergoing direct anterior total hip arthroplasty whose wounds were closed with 2-octyl cyanoacrylate with mesh. METHODS:This study was a retrospective review of 75 consecutive patients who underwent direct anterior total hi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000613544.11947.8b

    authors: Pachter CS,Garfinkel JH,Cochrane NH,Romness DW,Gladnick BP

    更新日期:2020-01-01 00:00:00

  • Utilization of living bilayered cell therapy (Apligraf) for heel ulcers.

    abstract::Among lower extremity chronic wounds, heel ulcers present one of the greatest challenges to the wound care provider. The potential for these ulcers to progress to osteomyelitis of the calcaneus is well known. The concept of "what to take off the wound" is a known clinical axiom; however, extensive debridement or surgi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000323504.68401.d6

    authors: Karr J

    更新日期:2008-06-01 00:00:00

  • Gene Expression of Angiotensin-Converting Enzyme 2 Receptor in Skin and the Implications for COVID-19.

    abstract:BACKGROUND:Binding to the angiotensin-converting enzyme 2 (ACE2) receptor is a critical step for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter target cells. This enzyme is expressed in many human tissues including the lungs, but no research has demonstrated that SARS-CoV-2 can infect human skin ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000722748.73437.7d

    authors: Al-Benna S

    更新日期:2021-01-01 00:00:00

  • Incidence and risk factors associated with pressure ulcers among patients with HIV infection.

    abstract:OBJECTIVE:To assess the incidence of and risk factors for pressure ulcers among patients with advanced human immunodeficiency virus type 1 (HIV-1) infection. DESIGN:Multicenter trial that included 1258 consecutive patients infected with HIV-1 who had 1815 admissions to 16 acute care infectious disease units in Italy. ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00129334-200406000-00011

    authors: Nicastri E,Viale P,Lyder CH,Cristini F,Martini L,Preziosi G,Dodi F,Irato L,Pan A,Petrosillo N,Gruppo HIV ed Infezioni Ospedaliere.

    更新日期:2004-06-01 00:00:00

  • Bitter Melon Extract Promotes Granulation Tissue Growth and Angiogenesis in the Diabetic Wound.

    abstract:OBJECTIVE:Bitter melon is a plant fruit that has been shown to exert a hypoglycemic effect when used systemically in patients with diabetes. This study was designed to investigate the topical effect of bitter melon on diabetic wounds using the wound chamber model in rats. DESIGN:Two bilateral wound chambers were impla...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000504758.86737.76

    authors: Singh R,Garcia-Gomez I,Gudehithlu KP,Singh AK

    更新日期:2017-01-01 00:00:00

  • In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria.

    abstract:OBJECTIVE:The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms. DESIGN:The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermid...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000363557.45726.41

    authors: Karau MJ,Piper KE,Steckelberg JM,Kavros SJ,Patel R

    更新日期:2010-07-01 00:00:00

  • Common nail disorders and fungal infections.

    abstract:PURPOSE:To provide the practitioner with current information on the most common nail disorders. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in wound care and related disorders. OBJECTIVES:After reading this article and taking this test, the reader should b...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000276409.53632.42

    authors: Alavi A,Woo K,Sibbald RG

    更新日期:2007-06-01 00:00:00

  • Don't let your revenue be part of the $4.9 billion returned to taxpayers!

    abstract::Wound care professionals should carefully inspect and audit their coding and billing practices in light of (1) the OIG's 2014 Semiannual Report to Congress and (2) the 2015 OIG Work Plan.You can read the details of both documents by following the Internet links provided earlier in this article. Conducting those self-a...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000459891.21303.0f

    authors: Schaum KD

    更新日期:2015-02-01 00:00:00

  • The Use of a Novel Canister-free Negative-Pressure Device in Chronic Wounds: A Retrospective Analysis.

    abstract:OBJECTIVE:Negative-pressure wound therapy (NPWT) is a mainstay in the treatment of acute and chronic wounds. Following the success of the Vacuum-Assisted Closure system (Kinetic Concepts Inc [KCI], an Acelity Company, San Antonio, Texas), many similar systems were developed with minor variations. However, these systems...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000481188.31032.52

    authors: Serena TE,Buan JS

    更新日期:2016-04-01 00:00:00

  • Treatment of ischemic wounds with noncontact, low-frequency ultrasound: the Mayo clinic experience, 2004-2006.

    abstract:OBJECTIVE:To evaluate the clinical role of a novel, noncontact, low-intensity, low-frequency ultrasound therapy (MIST Therapy) in the treatment of nonhealing leg and foot ulcers associated with chronic critical limb ischemia. DESIGN:Prospective, parallel-group, randomized, controlled trial. SETTING:A multidisciplinar...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000266660.88900.38

    authors: Kavros SJ,Miller JL,Hanna SW

    更新日期:2007-04-01 00:00:00

  • Results of Laboratory Testing for Immersion, Envelopment, and Horizontal Stiffness on Turn and Position Devices to Manage Pressure Injury.

    abstract:BACKGROUND:A continuing complication, pressure injuries are due to sustained mechanical loading and tissue deformations, which can then be exacerbated by additional intrinsic and extrinsic risk factors. Although support surfaces are designed to mitigate risk factors for pressure injuries, the presence of a turn and pos...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000696412.04000.98

    authors: Call E,Tanner L,Cheney A,Rappl L,Santamaria N,Gefen A,Oberg C

    更新日期:2020-10-01 00:00:00

  • Improvement of periulcer skin condition in venous leg ulcer patients: prospective, randomized, controlled, single-blinded clinical trial comparing a biosynthetic cellulose dressing with a foam dressing.

    abstract:OBJECTIVES:The aim of this study was to investigate the influence of a biosynthetic cellulose wound dressing (BWD) to stimulate wound healing in patients with a venous leg ulcer on periulcer skin condition when compared with standard care using a foam dressing. METHODS:Each patient with a venous ulcer received compres...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000431237.22658.15

    authors: Dini V,Romanelli M,Andriessen A,Barbanera S,Bertone MS,Brilli C,Abel M

    更新日期:2013-08-01 00:00:00