Abstract:
INTRODUCTION:Urinary Bladder Matrix (UBM) is an extracellular matrix (ECM) scaffold. It is now used in wound care management of partial and full-thickness wounds where conventional methods for wound care usually fail to give satisfactory results. OBJECTIVE:In this study, the authors are comparing the healing of full-thickness excisional wounds in New Zealand rabbits using either UBM scaffolds alone or in combination with cultured keratinocytes. The wounds were compared grossly and histologically. MATERIALS AND METHODS:It is a comparative controlled study including 40 full-thickness wounds in 2 groups. Group (A) wounds: treated with UBM scaffolds, Group (B) wounds: treated with UBM scaffolds with cultured keratinocytes. The wounds were examined grossly after 1, 2, and 3 weeks, and were examined histologically at the end of the 3rd week using ordinary hematoxylin-eosin staining techniques. RESULTS:All the wounds healed completely by the end of the 3rd week. Early wound contraction was significantly less in group B. More angiogenic response was evident in all specimens of group B. CONCLUSION:This study shows that adding cultured keratinocytes to the rough surface of the UBM scaffold may be beneficial in reducing early wound contraction and improving wound vascularity in treatment of full-thickness wounds.
journal_name
Adv Skin Wound Carejournal_title
Advances in skin & wound careauthors
Eweida A,Saad M,Gabr E,Marei M,Khalil MRdoi
10.1097/01.ASW.0000398665.51283.44subject
Has Abstractpub_date
2011-06-01 00:00:00pages
268-73issue
6eissn
1527-7941issn
1538-8654pii
00129334-201106000-00007journal_volume
24pub_type
杂志文章abstract:PURPOSE:To provide information about initiating interdisciplinary research related to microbiomes and their role in human immunity, disease, and metabolic processes. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After parti...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000489561.52393.0e
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To provide an overview of moisture management and its importance in wound care. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able t...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000470851.27030.98
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:This study was conducted to: (1) determine the clinical effectiveness of a low-air-loss surface, VersaCare P500, in the prevention of pressure ulcers in surgical patients; (2) determine differences in the adjusted Braden scores between those using VersaCare and VersaCare P500 mattress surfaces; and (3) explor...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000396303.13582.70
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Patients with Crohn disease-related anal fistulas are treated with debridement of fistulous tracts and the placement of noncutting setons (NCSs). However, to reduce the high recurrence rate, there is still a need to develop more effective treatment methods. OBJECTIVE:To compare NCS with vacuum-assisted clos...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000547411.16017.58
更新日期:2019-01-01 00:00:00
abstract::Darier disease is an autosomal dominant skin disorder characterized by keratotic papules. After their appearance, these lesions tend to grow over time, producing large and exudative plaques that compromise the general condition of the affected patient's skin. The authors report the clinical case of a patient affected ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000694144.13825.59
更新日期:2020-10-01 00:00:00
abstract:GENERAL PURPOSE:The purpose of this learning activity is to provide information about the Healthy Foot Screen, a new tool for assessment of common foot abnormalities. TARGET AUDIENCE:This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000530686.16243.d5
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical role of a novel, noncontact, low-intensity, low-frequency ultrasound therapy (MIST Therapy) in the treatment of nonhealing leg and foot ulcers associated with chronic critical limb ischemia. DESIGN:Prospective, parallel-group, randomized, controlled trial. SETTING:A multidisciplinar...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000266660.88900.38
更新日期:2007-04-01 00:00:00
abstract::Among lower extremity chronic wounds, heel ulcers present one of the greatest challenges to the wound care provider. The potential for these ulcers to progress to osteomyelitis of the calcaneus is well known. The concept of "what to take off the wound" is a known clinical axiom; however, extensive debridement or surgi...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000323504.68401.d6
更新日期:2008-06-01 00:00:00
abstract::Wound care professionals should consider all this attention to the key word documentation as your 2015 "heads-up." You should conduct a self-audit and request an external audit of your own documentation against all the regulations, LCDs, Policy Articles, newsletters, and educational programs that CMS and your MACs are...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000459113.03360.09
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To review the etiology, anatomy, pathophysiology, differential diagnosis, and treatment of compartment syndrome. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in wound care. OBJECTIVES:After reading this article and taking this test, the reader shoul...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000294758.82178.45
更新日期:2007-10-01 00:00:00
abstract::Wound care professionals should carefully inspect and audit their coding and billing practices in light of (1) the OIG's 2014 Semiannual Report to Congress and (2) the 2015 OIG Work Plan.You can read the details of both documents by following the Internet links provided earlier in this article. Conducting those self-a...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000459891.21303.0f
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Lymphedema is a condition of localized protein-rich swelling from damaged or malfunctioning lymphatics. Because the immune system is compromised, there is a high risk of infection. Infection in patients with lymphedema may present in a variety of ways. OBJECTIVE:The goals of this review were to standardize ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000520501.23702.82
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To describe the care of pediatric patients who had a gastrostomy and developed peristomal lesions and received a systematic single adapted crusting technique in a pediatric ICU in a tertiary Brazilian hospital. METHODS:An analysis of six cases presenting traumatic, noninfectious peristomal lesions with ostiu...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000661788.68292.81
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To construct a quickly and easily administered nutrition screening tool using variables believed to be predictive of malnutrition risk in the wound patient population. DESIGN:A prospective pilot study assessed patients on a list of suspected variables, as well as the Scored Patient-Generated Subjective Globa...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000479803.09658.cb
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the use of a transdermal sustained oxygen delivery system to promote the healing of chronic lower extremity wounds in patients with diabetes. METHODS:Six patients (5 men, 1 woman; age range, 32-77 years) with diabetes and chronic lower extremity wounds unresponsive to previous multimodal therapy ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000343722.22943.40
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Fasciotomy incision closure is often performed with skin grafts that can lead to cosmetic and functional complications after surgical intervention. Because fasciotomy incisions do not result in skin loss, the authors hypothesized that better closure can be achieved by reducing tissue edema with negative-pres...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000672492.38463.58
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:A recently described technique proposes a simple method to achieve permanent hemostasis of distal fingertip dermal avulsion injuries. It is simple to learn and easy to perform with readily available materials found in most emergency departments. However, long-term outcomes for patients treated with this techn...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000521049.72160.37
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To enhance the learner's competence with knowledge of the results of research examining suspected deep tissue injury profiles. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational ac...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000443267.25288.87
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To conduct a cost-of-illness study of pressure ulcers in the Netherlands for different care settings, including home care, nursing homes, general hospitals, and university hospitals. DESIGN:A cost-of-illness study was conducted based on prevalence figures and expert opinion. A differential cost study approac...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/00129334-200203000-00008
更新日期:2002-03-01 00:00:00
abstract:GENERAL PURPOSE:To present an evaluation of a surfactant-containing polymeric membrane foam wound dressing for use on patients with chronic pilonidal sinus disease. TARGET AUDIENCE:This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in s...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000534702.34915.90
更新日期:2018-07-01 00:00:00
abstract::The heel is the second most common area where patients develop pressure ulcers (PrUs). Some of the interventions commonly used today to prevent PrUs have not been empirically tested, whereas other interventions have been studied and shown to prevent heel PrUs. Currently, there are no specific studies comparing a press...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000412909.81452.b6
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of different dressing methods on the wound healing process after pilonidal sinus surgery. METHODS:In this clinical trial, 60 patients undergoing pilonidal sinus surgery were randomly assigned to one of three groups. In the first group, hydrogel or alginate and hydrocolloid compounds we...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000558268.59745.d2
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Lucilia sericata maggots are applied to chronic wounds to aid healing when conventional treatments have failed. After their application into a necrotic wound, they potentially influence wound healing with a combination of specific proteinases that are involved in the remodeling of extracellular matrix. These...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000461260.03630.a0
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to test the efficacy of a wound support network model between the primary home care service and the hospital. The impact on wound healing rate, cost benefit, and transfer of knowledge was investigated. INTERVENTION:The intervention group was exposed to a wound support network (n = 3...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000499714.97688.4b
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the peer-reviewed literature that compares advanced venous leg ulcer therapies to standard of care with compression dressings. METHODS:A MEDLINE search for venous ulcer treatment with electrical stimulation, surgical vein correction, and bioengineered tissues was conducted. Randomized clinical tr...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000462328.60670.c3
更新日期:2015-04-01 00:00:00
abstract:GENERAL PURPOSE:To increase health care professionals' awareness and perceptions of the skin as one of the largest body organs with multidimensional aspects and significant implications for interprofessional collaboration in whole-person care. TARGET AUDIENCE:This continuing education activity is intended for physicia...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000557830.01516.6b
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To provide physicians and nurses with an overview of diabetic foot assessment. TARGET AUDIENCE:This continuing-education activity is intended for physicians and nurses with an interest in learning about proper diabetic foot assessment. OBJECTIVES:After reading the article and taking the test, the participant ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/00129334-200303000-00007
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To assess the incidence of and risk factors for pressure ulcers among patients with advanced human immunodeficiency virus type 1 (HIV-1) infection. DESIGN:Multicenter trial that included 1258 consecutive patients infected with HIV-1 who had 1815 admissions to 16 acute care infectious disease units in Italy. ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,多中心研究
doi:10.1097/00129334-200406000-00011
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:: The purpose of this study was to assess Inlow's 60-Second Diabetic Foot Screen Tool to ascertain consistency of risk recognition for development of ulceration independent of specific assessor and practice setting. Screening tools that assist clinicians in identifying risk require validation. The objectives ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000415343.45178.91
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To enhance the learner's competence with knowledge of the effectiveness of shear-reducing insoles for prevention of foot ulceration in patients with high-risk diabetes. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000422625.17407.93
更新日期:2012-11-01 00:00:00