Wound Healing Studies Using Punica granatum Peel: An Animal Experimental Study.

Abstract:

OBJECTIVE:The goal of the present study was to evaluate the effects of hydroalcoholic extract-based carboxy methyl cellulose (CMC) gel of Punica granatum peel (PCMC) and CMC on healing of full-thickness skin wounds. MATERIALS AND METHODS:Forty-two rats were studied. Each rat had 3 wounds that were treated topically with PCMC as the case, CMC as the positive control, and sterile saline as the negative control. All 3 wounds of each rat were photographed during the wound healing period at days 0 (onset of wound surgery), 3, 6, 9, and 12.The wound area was calculated using Adobe Photoshop CS (version 5) software (Adobe Systems Inc, San Jose, California). Electrocardiogram paper was used for reference scale. RESULTS:The results of this study show that macroscopic and microscopic wound healing took a significantly longer time in wounds treated with normal saline than those treated with PCMC (grossly) and CMC gel (grossly and significantly). CONCLUSIONS:The authors' findings show that anti-inflammatory, antihemorrhagic, and antinecrotic effects of CMC lead to early healing of skin wounds.

journal_name

Adv Skin Wound Care

authors

Zekavat O,Amanat A,Karami M,Paydar S,Gramizadeh B,Zareian-Jahromi M

doi

10.1097/01.ASW.0000481116.16998.55

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

217-25

issue

5

eissn

1527-7941

issn

1538-8654

pii

00129334-201605000-00006

journal_volume

29

pub_type

杂志文章
  • Effectiveness of Arginine Supplementation on Wound Healing in Older Adults in Acute and Chronic Settings: A Systematic Review.

    abstract:OBJECTIVE:To examine the effect of arginine supplementation on wound healing, as measured by wound size and healing rate, in older adults in acute and long-term care (LTC) settings. DATA SOURCES:PubMed, CINAHL Plus, Google Scholar, and OpenGrey databases. STUDY SELECTION:Randomized clinical trials and clinical studie...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000579700.20404.56

    authors: Schneider KL,Yahia N

    更新日期:2019-10-01 00:00:00

  • Development of a Nutrition Screening Tool for an Outpatient Wound Center.

    abstract:OBJECTIVE:To construct a quickly and easily administered nutrition screening tool using variables believed to be predictive of malnutrition risk in the wound patient population. DESIGN:A prospective pilot study assessed patients on a list of suspected variables, as well as the Scored Patient-Generated Subjective Globa...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000479803.09658.cb

    authors: Fulton J,Evans B,Miller S,Blasiole KN,Leone R,Beinlich N,Meehan A,Loose C

    更新日期:2016-03-01 00:00:00

  • Stereologic study of the effects of prostaglandin E2 on the induction of angiogenesis in full-thickness skin autografts.

    abstract:OBJECTIVE:To determine whether prostaglandin E2 improves angiogenesis in full-thickness skin grafts. DESIGN:Randomized study SUBJECTS:20 male rabbits, divided into 2 experimental and 2 control groups. METHODOLOGY:Prostaglandin E2 (experimental groups) or prostaglandin E2 vehicle (control groups) was injected locally...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/00129334-200405000-00020

    authors: Khozani TT,Noorafshan A,Nikeghbalian S,Panjeh-Shahin MR,Dehghani F,Azizi M,Tanideh N

    更新日期:2004-05-01 00:00:00

  • Utilization of living bilayered cell therapy (Apligraf) for heel ulcers.

    abstract::Among lower extremity chronic wounds, heel ulcers present one of the greatest challenges to the wound care provider. The potential for these ulcers to progress to osteomyelitis of the calcaneus is well known. The concept of "what to take off the wound" is a known clinical axiom; however, extensive debridement or surgi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000323504.68401.d6

    authors: Karr J

    更新日期:2008-06-01 00:00:00

  • Optimizing the Moisture Management Tightrope with Wound Bed Preparation 2015©.

    abstract:PURPOSE:To provide an overview of moisture management and its importance in wound care. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able t...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000470851.27030.98

    authors: Sibbald RG,Elliott JA,Ayello EA,Somayaji R

    更新日期:2015-10-01 00:00:00

  • Evaluating the Effects of a Pressure Injury Prevention Algorithm.

    abstract:OBJECTIVE:To evaluate the effect of a pressure injury prevention algorithm on pressure injury prevention. DESIGN, SETTING, AND PARTICIPANTS:This intervention study was conducted in the anesthesiology and reanimation ICU (ARICU) of a university hospital. The study included two sample groups (nurses and patients). All p...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000553597.18658.6b

    authors: Yilmazer T,Bulut H

    更新日期:2019-06-01 00:00:00

  • Construction and Validation of an Instrument for Assessing the Feet of Persons with Diabetes.

    abstract:OBJECTIVE:To construct and validate an assessment instrument to evaluate the feet of people with diabetes mellitus in Brazil. METHODS:Methodological research developed in three stages: construction of the Assessment Instrument for the Feet of People with Diabetes Mellitus, validation of face and content validity, and ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000658588.28614.96

    authors: da Costa SP,Chavaglia SRR,Ohl RIB,Costa BY,Barbosa MH,Woo K,Gamba MA

    更新日期:2020-05-01 00:00:00

  • Proxy study on minimizing risk of sacral pressure ulcers while complying with ventilator-associated pneumonia risk reduction guidelines.

    abstract::Bed positioning poses a subtle, yet important, tradeoff in the competing needs of hospitalized patients, particularly those susceptible to lower respiratory tract infections and/or pressure ulcers. Although it is widely held that a minimum 30° incline is necessary to mitigate risk of ventilator-acquired pneumonia, it ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000471877.19459.85

    authors: Crane BA,Wininger M,Kunsman M

    更新日期:2015-12-01 00:00:00

  • Diagnosing and treating moisture-associated skin damage.

    abstract::Certain types of moisture can cause debilitating damage to the skin. Terms such as perineal dermatitis, diaper rash, incontinence-associated dermatitis, or moisture-associated skin damage describe some of the conditions caused by moisture from wound drainage, fecal and/or urinary incontinence, and perspiration. It is ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000414707.33267.92

    authors: Zulkowski K

    更新日期:2012-05-01 00:00:00

  • The relationship between hemoglobin A(1c) values and healing time for lower extremity ulcers in individuals with diabetes.

    abstract:PROBLEM:The diabetic population is at an increased risk, up to 15% over a lifetime, to develop leg and foot ulcers due to such factors as neuropathy, ischemia, and infection. The tight control of glucose levels as possible is necessary to prevent the diabetic complications by preventing microvascular changes that predi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000358639.45784.cd

    authors: Markuson M,Hanson D,Anderson J,Langemo D,Hunter S,Thompson P,Paulson R,Rustvang D

    更新日期:2009-08-01 00:00:00

  • Cultured keratinocytes on urinary bladder matrix scaffolds increase angiogenesis and help in rapid healing of wounds.

    abstract:INTRODUCTION:Urinary Bladder Matrix (UBM) is an extracellular matrix (ECM) scaffold. It is now used in wound care management of partial and full-thickness wounds where conventional methods for wound care usually fail to give satisfactory results. OBJECTIVE:In this study, the authors are comparing the healing of full-t...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000398665.51283.44

    authors: Eweida A,Saad M,Gabr E,Marei M,Khalil MR

    更新日期:2011-06-01 00:00:00

  • A Quantitative Analysis of Microcirculation in Skin Defects Covered with Topical Wound Dressings or a Newly Developed Collagen Matrix.

    abstract:OBJECTIVE:Innovative skin substitutes and temporary wound dressings are frequently used in the treatment of superficial and partial-thickness wounds. The aim of this study was to compare 2 commonly used temporary skin dressings with a newly developed collagen matrix to determine changes in microcirculation as measured ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000525848.21221.b8

    authors: Held M,Medved F,Petersen W,Tolzmann DS,Rahmanian-Schwarz A,Schaller HE,Rothenberger J

    更新日期:2017-11-01 00:00:00

  • Transdermal oxygen delivery to diabetic wounds: a report of 6 cases.

    abstract:OBJECTIVE:To evaluate the use of a transdermal sustained oxygen delivery system to promote the healing of chronic lower extremity wounds in patients with diabetes. METHODS:Six patients (5 men, 1 woman; age range, 32-77 years) with diabetes and chronic lower extremity wounds unresponsive to previous multimodal therapy ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000343722.22943.40

    authors: Hirsh F,Berlin SJ,Holtz A

    更新日期:2009-01-01 00:00:00

  • The Effect of Warm Compress Bistage Intervention on the Rate of Episiotomy, Perineal Trauma, and Postpartum Pain Intensity in Primiparous Women with Delayed Valsalva Maneuver Referring to the Selected Hospitals of Shiraz University of Medical Sciences in

    abstract:BACKGROUND:Genital trauma during vaginal delivery may result from episiotomy, spontaneous perineal tears (perineum, vagina), or both. In 2012, this study aimed to investigate the effect of warm compress bistage intervention on the rate of episiotomy, perineal trauma, and postpartum pain intensity in the primiparous wom...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000476073.96442.91

    authors: Akbarzadeh M,Vaziri F,Farahmand M,Masoudi Z,Amooee S,Zare N

    更新日期:2016-02-01 00:00:00

  • A Comparison of Three Dressing Methods for Pilonidal Sinus Surgery Wound Healing.

    abstract:OBJECTIVE:To evaluate the effect of different dressing methods on the wound healing process after pilonidal sinus surgery. METHODS:In this clinical trial, 60 patients undergoing pilonidal sinus surgery were randomly assigned to one of three groups. In the first group, hydrogel or alginate and hydrocolloid compounds we...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000558268.59745.d2

    authors: Sadati L,Froozesh R,Beyrami A,Khaneghah ZN,Elahi SA,Asl MF,Salehi T

    更新日期:2019-07-01 00:00:00

  • An Introduction to Skin as an Interface: Implications for Interprofessional Collaboration and Whole-Person Care.

    abstract:GENERAL PURPOSE:To increase health care professionals' awareness and perceptions of the skin as one of the largest body organs with multidimensional aspects and significant implications for interprofessional collaboration in whole-person care. TARGET AUDIENCE:This continuing education activity is intended for physicia...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000557830.01516.6b

    authors: Sherman DW,Kamel G

    更新日期:2019-06-01 00:00:00

  • Successful Fat Grafting in a Patient With Thromboangiitis Obliterans.

    abstract::Thromboangiitis obliterans, or Buerger disease, is a rare nonatherosclerotic segmental inflammatory vasculitis that generally affects young tobacco smokers. Although no surgical treatment is available, the most effective way to halt the disease's progress is smoking cessation. In this case report, a 29-year-old smoker...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000604192.77577.6f

    authors: D'Alessio I,Settembrini AM,Romagnoli S,Di Luca G,Domanin M,Gabrielli L

    更新日期:2019-12-01 00:00:00

  • Efficacy of Monitoring Devices in Support of Prevention of Pressure Injuries: Systematic Review and Meta-analysis.

    abstract:GENERAL PURPOSE:To present a systematic review of the literature assessing the efficacy of monitoring devices for reducing the risk of developing pressure injuries. TARGET AUDIENCE:This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in s...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/01.ASW.0000504579.83707.f6

    authors: Walia GS,Wong AL,Lo AY,Mackert GA,Carl HM,Pedreira RA,Bello R,Aquino CS,Padula WV,Sacks JM

    更新日期:2016-12-01 00:00:00

  • The cost of illness of pressure ulcers in The Netherlands.

    abstract:OBJECTIVE:To conduct a cost-of-illness study of pressure ulcers in the Netherlands for different care settings, including home care, nursing homes, general hospitals, and university hospitals. DESIGN:A cost-of-illness study was conducted based on prevalence figures and expert opinion. A differential cost study approac...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/00129334-200203000-00008

    authors: Severens JL,Habraken JM,Duivenvoorden S,Frederiks CM

    更新日期:2002-03-01 00:00:00

  • A comparison between the use of intravenous bags and the Heelift suspension boot to prevent pressure ulcers in orthopedic patients.

    abstract::The heel is the second most common area where patients develop pressure ulcers (PrUs). Some of the interventions commonly used today to prevent PrUs have not been empirically tested, whereas other interventions have been studied and shown to prevent heel PrUs. Currently, there are no specific studies comparing a press...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000412909.81452.b6

    authors: Bales I

    更新日期:2012-03-01 00:00:00

  • Evaluation of a new silicone adhesive tape among clinicians caring for patients with fragile or at-risk skin.

    abstract:OBJECTIVE:To evaluate performance of a new silicone tape among clinicians caring for patients with fragile skin. DESIGN:An international, multisite, 2-week-use evaluation. PARTICIPANTS AND SETTINGS:Caregivers (n = 217) from acute care hospitals in the United States, United Kingdom, and France who regularly use tapes ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.ASW.0000444646.43044.df

    authors: Manriquez S,Loperfido B,Smith G

    更新日期:2014-04-01 00:00:00

  • Incorporating Cutaneous and Wound Bacterial Bioburden Biomarkers into Clinical Research: A Review of Best Practices.

    abstract:PURPOSE:To provide information about initiating interdisciplinary research related to microbiomes and their role in human immunity, disease, and metabolic processes. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After parti...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000489561.52393.0e

    authors: Honaker J,Ammons C,Kelechi T

    更新日期:2016-09-01 00:00:00

  • Reverse Sural Adipofascial Flaps with Acellular Dermal Matrix and Negative-Pressure Wound Therapy.

    abstract::The reverse sural adipofascial flap (RSAF) is used to reconstruct challenging wounds of the foot and ankle. It offers several advantages over the traditional reverse sural flap, including less venous congestion. To complete the reconstruction, split-thickness skin grafting (STSG) may be done immediately or in a delaye...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000527290.81581.af

    authors: Pontell ME,Saad N,Winters BS,Daniel JN,Saad A

    更新日期:2018-01-01 00:00:00

  • Epidermal micrografts produced via an automated and minimally invasive tool form at the dermal/epidermal junction and contain proliferative cells that secrete wound healing growth factors.

    abstract:OBJECTIVE:The aim of this scientific study was to assess epidermal micrografts for formation at the dermal-epidermal (DE) junction, cellular outgrowth, and growth factor secretion. Epidermal harvesting is an autologous option that removes only the superficial epidermal layer of the skin, considerably limiting donor sit...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000470024.81711.b8

    authors: Osborne SN,Schmidt MA,Derrick K,Harper JR

    更新日期:2015-09-01 00:00:00

  • Physical assessment of the diabetic foot.

    abstract:PURPOSE:To provide physicians and nurses with an overview of diabetic foot assessment. TARGET AUDIENCE:This continuing-education activity is intended for physicians and nurses with an interest in learning about proper diabetic foot assessment. OBJECTIVES:After reading the article and taking the test, the participant ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/00129334-200303000-00007

    authors: Kravitz SR,McGuire J,Shanahan SD

    更新日期:2003-03-01 00:00:00

  • Evaluation of the incidence of pressure ulcers using hill-rom versacare surfaces.

    abstract:OBJECTIVE:This study was conducted to: (1) determine the clinical effectiveness of a low-air-loss surface, VersaCare P500, in the prevention of pressure ulcers in surgical patients; (2) determine differences in the adjusted Braden scores between those using VersaCare and VersaCare P500 mattress surfaces; and (3) explor...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000396303.13582.70

    authors: Korniewicz DM,Siegel J,Fajardo V,El-Masri M

    更新日期:2011-04-01 00:00:00

  • Outcomes in Patients Treated with a Novel, Simple Method for Hemostasis of Dermal Avulsion Injuries.

    abstract:OBJECTIVE:A recently described technique proposes a simple method to achieve permanent hemostasis of distal fingertip dermal avulsion injuries. It is simple to learn and easy to perform with readily available materials found in most emergency departments. However, long-term outcomes for patients treated with this techn...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000521049.72160.37

    authors: Dowling ST,Lin BW

    更新日期:2017-10-01 00:00:00

  • The Use of a Novel Canister-free Negative-Pressure Device in Chronic Wounds: A Retrospective Analysis.

    abstract:OBJECTIVE:Negative-pressure wound therapy (NPWT) is a mainstay in the treatment of acute and chronic wounds. Following the success of the Vacuum-Assisted Closure system (Kinetic Concepts Inc [KCI], an Acelity Company, San Antonio, Texas), many similar systems were developed with minor variations. However, these systems...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000481188.31032.52

    authors: Serena TE,Buan JS

    更新日期:2016-04-01 00:00:00

  • Comparison of the cytotoxicities and wound healing effects of hyaluronan, carbomer, and alginate on skin cells in vitro.

    abstract:OBJECTIVE:To compare the cytotoxicities and efficacy of hyaluronan (HA), carbomer, and sodium alginate on repairing thermal-injured cells and promoting cell migration. DESIGN:The 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetra-zoliumromide method was used to evaluate the cytotoxicities of HA, carbomer, and sodium a...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000467303.39079.59

    authors: Guo X,Huang S,Sun J,Wang F

    更新日期:2015-09-01 00:00:00

  • Common nail disorders and fungal infections.

    abstract:PURPOSE:To provide the practitioner with current information on the most common nail disorders. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in wound care and related disorders. OBJECTIVES:After reading this article and taking this test, the reader should b...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000276409.53632.42

    authors: Alavi A,Woo K,Sibbald RG

    更新日期:2007-06-01 00:00:00