Histological classification of schistosomal egg induced polyps of colon and their clinical significance. An analysis of 272 cases.

Abstract:

:272 cases of schistosomal egg induced polyps collected from mass-screening for colorectal carcinoma in Jiashan County were divided into 3 types: fibrous type (FT), mixed type (MT) and epithelial proliferative type (ET). The ET was characterized by crypt elongation, hypertrophy, variation in size, disorderly arrangement, as well as the high percentage of atypical hyperplasia (64.9%). The coexistence and transition between inflammatory reactive hyperplastic and neoplastic crypts were noticed. By HID/AB staining, sialomucins were increased in ET, CEA and PNA receptors detected by the ABC method were present in 18/20 and 6/18 of ET respectively. The mucin expression of ET was similar to that of adenomas. It is likely that a spectrum of ET, atypical hyperplasia and adenoma may exist. We suggest that the patients with ET, especially those with atypical hyperplasia, should be regarded as "risk group", and close follow-up is needed.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Yu XR,Chen PH,Xu JY,Xiao S,Shan ZJ,Zhu SJ

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

64-70

issue

1

eissn

0366-6999

issn

2542-5641

journal_volume

104

pub_type

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