A two-site, population-based study of barriers to cataract surgery in rural china.

Abstract:

PURPOSE:China has among the lowest cataract surgical rates in Asia. This study was conducted to identify barriers to cataract surgery in rural China. METHODS:All subjects having undergone cataract surgery and persons with presenting visual acuity or=1 eye due to nonsurgically treated cataract were identified in two population-based studies in southern (Yangjiang) and northern (Handan) China. The subjects were administered a questionnaire assessing attitudes in four areas constituting potential barriers to surgery: knowledge about cataract, perceptions of local surgical quality, transportation and cost, and available resources. RESULTS:Interviews were completed on 71% to 86% of eligible subjects in both sites. Interviewed subjects did not differ significantly from nonrespondents with regard to age, sex, and presenting acuity in the better-seeing eye. A total of 214 (80.4%) nonsurgical and 131 (76.6%) surgical participants were interviewed, with a mean age of 71.8 +/- 8.0 and 73.7 +/- 7.4 years, respectively (P > 0.1). Among the nonsurgical subjects, 67.8% were blind (presenting vision, or=1 eye due to cataract, whereas among the surgical participants, 25.2% remained blind in the eye that had undergone surgical removal of the cataract. In a multivariate analysis adjusted for age, sex, and site, increased knowledge and higher estimates of the quality of surgery were associated with having had surgery, whereas cost and transportation scores were not. CONCLUSIONS:Lack of knowledge about cataract and concerns about the quality of local services appear to be the principal barriers to cataract surgery in rural China.

authors

Yin Q,Hu A,Liang Y,Zhang J,He M,Lam DS,Ge J,Wang N,Friedman DS,Zhao J,Congdon N

doi

10.1167/iovs.08-2783

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

1069-75

issue

3

eissn

0146-0404

issn

1552-5783

pii

iovs.08-2783

journal_volume

50

pub_type

杂志文章,多中心研究
  • Analysis of retinal vasodilation after flicker light stimulation in relation to vasospastic propensity.

    abstract:PURPOSE:To explore the maximum retinal vasodilation in response to repeated flicker light stimulation in relation to vasospastic propensity in healthy subjects. METHODS:Twenty-four young healthy women were grouped as vasospastic and nonvasospastic, based on their history of cold extremities and on the results of nailf...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-0351

    authors: Gugleta K,Zawinka C,Rickenbacher I,Kochkorov A,Katamay R,Flammer J,Orgul S

    更新日期:2006-09-01 00:00:00

  • Macular choroidal thickness in unilateral amblyopic children.

    abstract:PURPOSE:To investigate the choroidal thickness (CT) in children with amblyopia through spectral-domain optical coherence tomography (SD-OCT). METHODS:Thirty-seven children with unilateral amblyopia and 22 children with normal vision participated in the study. Cross-sectional images of the choroid of evaluated eyes wer...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.14-14439

    authors: Xu J,Zheng J,Yu S,Sun Z,Zheng W,Qu P,Chen Y,Chen W,Yu X

    更新日期:2014-10-14 00:00:00

  • Enhancing Rose Bengal-Photosensitized Protein Crosslinking in the Cornea.

    abstract:Purpose:Rose bengal (RB)-photosensitized protein crosslinking has been proposed for several applications in the eye. This study identifies oxygen-dependent and oxygen-independent mechanistic pathways in cornea for RB-photosensitized crosslinking to enhance its efficiency for ocular treatments. Methods:Rabbit corneas e...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.19-26604

    authors: Wertheimer CM,Elhardt C,Kaminsky SM,Pham L,Pei Q,Mendes B,Afshar S,Kochevar IE

    更新日期:2019-05-01 00:00:00

  • Intracellular pH regulation in fresh and cultured bovine corneal endothelium. I. Na+/H+ exchange in the absence and presence of HCO3-.

    abstract::A detailed comparison of intracellular pH (pHi) regulatory mechanisms was made between fresh (FBCE) and cultured (CBCE) bovine corneal endothelium to: (1) identify the ion transport mechanisms that could directly or indirectly affect transendothelial HCO3- transport; and (2) determine if cultured cells could serve as ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Bonanno JA,Giasson C

    更新日期:1992-10-01 00:00:00

  • Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo.

    abstract:PURPOSE:To determine the impact of repetitive nonlethal oxidant injury with hydroquinone (HQ) on regulation of cell membrane blebbing and molecules, which are essential in extracellular matrix turnover (ECM) maintenance, especially matrix metalloproteinase (MMP)-2, tissue inhibitor of MMP (TIMP)-2, and type IV collagen...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-1230

    authors: Marin-Castaño ME,Striker GE,Alcazar O,Catanuto P,Espinosa-Heidmann DG,Cousins SW

    更新日期:2006-09-01 00:00:00

  • Ocular dominance, laterality, and refraction in Singaporean children.

    abstract:PURPOSE:To explore the effect of dominance and laterality on refractive error and axial length. METHODS:Ocular dominance was assessed with the hole-in-the-card test in 543 children during their 2006 follow-up visits for the Singapore Cohort study Of the Risk factors for Myopia (SCORM). Data were compared to cycloplegi...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-1489

    authors: Chia A,Jaurigue A,Gazzard G,Wang Y,Tan D,Stone RA,Saw SM

    更新日期:2007-08-01 00:00:00

  • Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats.

    abstract::PURPOSE. To investigate the anti-inflammatory effect of aminoimidazole carboxamide ribonucleotide (AICAR), an analog of adenosine monophosphate (AMP), in endotoxin-induced uveitis (EIU). METHODS. EIU was induced by subcutaneous injection of lipopolysaccharide (LPS) (200 μg) in Lewis rats. AICAR (50 mg/kg, intraperiton...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-7331

    authors: Suzuki J,Manola A,Murakami Y,Morizane Y,Takeuchi K,Kayama M,Miller JW,Sobrin L,Vavvas DG

    更新日期:2011-08-22 00:00:00

  • Innervation of the superior tarsal (Müller's) muscle in the cynomolgus monkey: a retrograde tracing study.

    abstract:PURPOSE:The retrograde transport of wheat germ agglutinin-horseradish peroxidase (WGA/HRP) was used to study the localization of the neurons that innervate the superior tarsal muscle in the cynomolgus monkey. METHODS:A 5-10% WGA-HRP solution was applied to the medial part of the superior tarsal muscle. Seventy-two hou...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: van der Werf F,Baljet B,Prins M,Timmerman A,Otto JA

    更新日期:1993-06-01 00:00:00

  • Activation of protein tyrosine phosphorylation after retinal branch vein occlusion in cats.

    abstract:PURPOSE:The authors examine the effect of retinal branch vein occlusion (BVO), a common retinal vascular disorder, on protein tyrosine phosphorylation, production of angiogenic growth factors, and activation of signal proteins in the tyrosine kinase pathways in the retina. METHODS:Retinal branch vein occlusion was ind...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Hayashi A,Imai K,Kim HC,de Juan E Jr

    更新日期:1997-02-01 00:00:00

  • Anti-Inflammatory and Antioxidative Effects of Camellia japonica on Human Corneal Epithelial Cells and Experimental Dry Eye: In Vivo and In Vitro Study.

    abstract:Purpose:To analyze the anti-inflammatory and antioxidative effects of Camellia japonica (CJ) on human corneal epithelial (HCE) cells and its therapeutic effects in a mouse model of experimental dry eye (EDE). Methods:Camellia japonica extracts of varying concentrations (0.001%, 0.01%, and 0.1%) were used to treat HCE ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.16-20634

    authors: Lee HS,Choi JH,Cui L,Li Y,Yang JM,Yun JJ,Jung JE,Choi W,Yoon KC

    更新日期:2017-02-01 00:00:00

  • Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina.

    abstract:PURPOSE:Activation of complement has been implicated as one of the major causes of age-related macular degeneration (AMD). Evidence is accumulating for a role of complement in other retinal diseases, such as diabetic retinopathy and proliferative vitreoretinopathy. Because of the paucity of animal models that directly ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.10-6002

    authors: Cashman SM,Desai A,Ramo K,Kumar-Singh R

    更新日期:2011-05-18 00:00:00

  • Molecular cloning, membrane topology, and localization of bovine rom-1 in rod and cone photoreceptor cells.

    abstract:PURPOSE:To characterize the molecular properties, cellular distribution, and subcellular distribution of bovine rom-1 and its interaction with peripherin/rds in photoreceptor cells as an important step toward elucidating the role of rom-1 in photoreceptor outer segment structure-function relationships and in inherited ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Moritz OL,Molday RS

    更新日期:1996-02-01 00:00:00

  • Normal square wave jerks.

    abstract::Fixation stability of the saccadic system was investigated by infrared reflection oculography in 29 normal subjects, young and elderly. Square wave jerks consisting of spontaneous horizontal saccadic excursions of 0.5 degree and over, followed some 200 msec later by corrective saccades, were recorded in 24% of subject...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Herishanu YO,Sharpe JA

    更新日期:1981-02-01 00:00:00

  • Ceramide-1-phosphate, a new mediator of development and survival in retina photoreceptors.

    abstract::PURPOSE. Simple sphingolipids control crucial cellular processes in several cell types. Previous work demonstrated that sphingolipids, such as ceramide, sphingosine, and sphingosine-1-phosphate, are key mediators in the regulation of survival, differentiation, and proliferation of retina photoreceptors. Ceramide-1-pho...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.10-7065

    authors: Miranda GE,Abrahan CE,Agnolazza DL,Politi LE,Rotstein NP

    更新日期:2011-08-22 00:00:00

  • Disruption of the retinal parafoveal capillary network in type 2 diabetes before the onset of diabetic retinopathy.

    abstract:PURPOSE:To establish, using adaptive optics scanning laser ophthalmoscopy (AOSLO), that the retinal parafoveal capillary network is altered before the onset of diabetic retinopathy in adult patients with type 2 diabetes. METHODS:AOSLO videos were acquired in the parafoveal region of one eye from control subjects and f...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-8481

    authors: Tam J,Dhamdhere KP,Tiruveedhula P,Manzanera S,Barez S,Bearse MA Jr,Adams AJ,Roorda A

    更新日期:2011-11-29 00:00:00

  • Laser scanning in vivo confocal microscopy reveals reduced innervation and reduction in cell density in all layers of the keratoconic cornea.

    abstract:PURPOSE:The exact pathophysiological processes underlying keratoconus remain an enigma. In this study, laser scanning in vivo confocal microscopy (IVCM) was used to define further the microstructural abnormalities in the keratoconic cornea and to establish the relationship with disease severity. METHODS:This was a pro...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.07-0968

    authors: Niederer RL,Perumal D,Sherwin T,McGhee CN

    更新日期:2008-07-01 00:00:00

  • The Urokinase Receptor-Derived Peptide UPARANT Recovers Dysfunctional Electroretinogram and Blood-Retinal Barrier Leakage in a Rat Model of Diabetes.

    abstract:Purpose:The activation of the urokinase-type plasminogen activator and its receptor system is associated with retinal diseases. Among peptide inhibitors of this system, UPARANT acts by preventing the onset of pathologic signs of neovascular ocular diseases. We investigated whether systemic UPARANT may act in a therapeu...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.17-21593

    authors: Cammalleri M,Locri F,Marsili S,Dal Monte M,Pisano C,Mancinelli A,Lista L,Rusciano D,De Rosa M,Pavone V,Bagnoli P

    更新日期:2017-06-01 00:00:00

  • Staining characteristics and antiviral activity of sulforhodamine B and lissamine green B.

    abstract:PURPOSE:Fluorescein and rose bengal are dyes used routinely in the examination of the ocular surface. As part of an ongoing search for a superior ophthalmic dye with optimal specificity and sensitivity and a lack of interference with subsequent viral cultures, and as part of studies that use chemical dyes to understand...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Chodosh J,Dix RD,Howell RC,Stroop WG,Tseng SC

    更新日期:1994-03-01 00:00:00

  • Enhanced induction of a 72 kDa heat shock protein in cultured retroocular fibroblasts.

    abstract::Fibroblasts in the retroocular connective tissue appear to play a central role in the pathogenesis of Graves' ophthalmopathy (GO). We hypothesize that specific attributes, differentiating normal from GO retroocular fibroblasts, may render the latter more vulnerable to the ongoing immunopathological process in GO. We i...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Heufelder AE,Wenzel BE,Bahn RS

    更新日期:1992-02-01 00:00:00

  • Role of swarming migration in the pathogenesis of bacillus endophthalmitis.

    abstract:PURPOSE:Bacillus cereus causes one of the most rapidly blinding forms of bacterial endophthalmitis. Migration of B. cereus throughout the eye during endophthalmitis is a unique aspect of this disease that may contribute to intraocular virulence. This study was conducted to analyze the contribution of swarming and intra...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-0301

    authors: Callegan MC,Novosad BD,Ramirez R,Ghelardi E,Senesi S

    更新日期:2006-10-01 00:00:00

  • The effects of short-term experimental strabismus on the visual system in Macaca mulatta.

    abstract::Experimental esotropia was produced surgically in infant rhesus monkeys (Macaca mulatta) for brief periods of time. Electrophysiological studies of the visual cortex showed that esotropia of only 2 weeks duration in an infant monkey is sufficient to cause a marked shift of dominance in favor of the fixating eye and to...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Crawford ML,von Noorden GK

    更新日期:1979-05-01 00:00:00

  • Genotype-phenotype correlation of mouse pde6b mutations.

    abstract:PURPOSE:To identify the underlying molecular defects causing retinal degeneration in seven N-ethyl-N-nitrosourea (ENU) induced mutant alleles of the Pde6b gene and to analyze the timescale of retinal degeneration in these new models of retinitis pigmentosa. METHODS:Conformation sensitive capillary electrophoresis and ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-0254

    authors: Hart AW,McKie L,Morgan JE,Gautier P,West K,Jackson IJ,Cross SH

    更新日期:2005-09-01 00:00:00

  • Confirmation of the validity of the psychophysical light scattering factor.

    abstract:PURPOSE:To reevaluate the validity of the light scatter factor (LSF) formula of Paulsson and Sjöstrand, LSF = L/E (M2/M1-1), where L is the target luminance, E is the illuminance of the glare source at the eye, and M2 and M1 are modulation contrast thresholds measured with and without the glare source, respectively. Th...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Whitaker D,Elliott DB,Steen R

    更新日期:1994-01-01 00:00:00

  • Integrin alphavbeta5 participates in the binding of photoreceptor rod outer segments during phagocytosis by cultured human retinal pigment epithelium.

    abstract:PURPOSE:To examine the expression of integrin vitronectin receptors (integrins alphavbeta3 and alphavbeta5) in native human fetal retinal pigment epithelium (RPE) and cultured hunman fetal RPE and to examine the role of RPE VnRs in the phagocytosis of photoreceptor rod outer segments (ROS). METHODS:Monoclonal antibodi...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Lin H,Clegg DO

    更新日期:1998-08-01 00:00:00

  • Characterization of cholinesterase activities in primary cultures of retinal pigment epithelium.

    abstract::This report presents a comparative description of the acetylcholinesterase and butyrylcholinesterase activities and their molecular forms in primary cultures of retinal pigment epithelium (RPE). Acetylcholinesterase activity increases during differentiation of the cells. Sucrose sedimentation analysis of acetylcholine...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Salceda R,Sánchez G,León-Cázares JM

    更新日期:1992-04-01 00:00:00

  • Anion channels in the apical membrane of mammalian corneal epithelium primary cultures.

    abstract::Chloride ion (Cl-) secretion by the rabbit corneal epithelium involves a catecholamine-stimulated Cl- conductance at the apical membrane, but the characteristics of the ion channel(s) responsible are unknown. A primary cell culture system was developed that induces stratified epithelial differentiation of rat and rabb...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Marshall WS,Hanrahan JW

    更新日期:1991-04-01 00:00:00

  • IPSC-Derived Corneal Endothelial-like Cells Act as an Appropriate Model System to Assess the Impact of SLC4A11 Variants on Pre-mRNA Splicing.

    abstract:Purpose:To report molecular genetic findings in six probands with congenital hereditary endothelial dystrophy (CHED) variably associated with hearing loss (also known as Harboyan syndrome). Furthermore, we developed a cellular model to determine if disease-associated variants induce aberrant SLC4A11 pre-mRNA splicing. ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.19-26930

    authors: Brejchova K,Dudakova L,Skalicka P,Dobrovolny R,Masek P,Putzova M,Moosajee M,Tuft SJ,Davidson AE,Liskova P

    更新日期:2019-07-01 00:00:00

  • Stretch to see: lateral tension strongly determines cell survival in long-term cultures of adult porcine retina.

    abstract:PURPOSE:To explore the effect of lateral tension as a survival factor for retinal explants in vitro. The central nervous system (CNS) resides in a highly mechanical milieu. However, the importance of biomechanical homeostasis for normal CNS function has not been extensively explored. Diseases in which normal mechanical...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.12-11420

    authors: Taylor L,Moran D,Arnér K,Warrant E,Ghosh F

    更新日期:2013-03-13 00:00:00

  • Th1 versus Th2 immune responses in autoimmune lacrimal gland disease in MRL/Mp mice.

    abstract:PURPOSE:In MRL/Mp-lpr/lpr (MRL/lpr) and MRL/Mp-+/+ (MRL/+) mice, a T-cell-driven lacrimal gland inflammation spontaneously develops that is a model for Sjögren's syndrome. The lacrimal gland lesions in these mice were evaluated by immunohistochemistry for the relative contributions of T-helper (Th)1 versus Th2 immune r...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Jabs DA,Lee B,Whittum-Hudson JA,Prendergast RA

    更新日期:2000-03-01 00:00:00

  • The Stiles-Crawford effect in retinitis pigmentosa.

    abstract::Stiles-Crawford functions were obtained from the maculas of 22 patients with different genetic types of retinitis pigmentosa and visual acuity of 20/40 or better. Reduced cone directional sensitivity was seen in the fovea with both focal cone electroretinographic testing and psychophysical testing. Functions from the ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Birch DG,Sandberg MA,Berson EL

    更新日期:1982-02-01 00:00:00