Abstract:
PURPOSE:A scientific review panel for the US Food and Drug Administration (FDA) recently identified the need for more data on the health risk of mercury exposure from dental amalgam among susceptible populations. We evaluated impacts of low-level mercury exposure on renal function and neurobehavioral and neuropsychological performance among children. METHODS:Dental histories for 403 children aged 7-11 years in five schools from Xuhui, Shanghai were checked by dentists. Of them, 198 with confirmed amalgam fillings were recruited (exposure group). Reference children (N=205) were those who never had dental amalgam treatment. In May 2004, each child provided a urine sample for measurements of total mercury, N-acetyl-beta-D-glucosaminidase activity, microalbumin, and creatinine (Cr). The Child Behavior Checklist, Eysenck Personality Questionnaire, and an intelligence screening test were administered. RESULTS:The geometric mean urinary mercury concentration was 1.6 microg/g Cr for children with and 1.4 microg/g Cr for children without amalgam fillings. No differences were found between children with and without fillings for either renal function biomarker, or on neurobehavioral, neuropsychological, or intelligence tests. CONCLUSIONS:Although urinary mercury concentration was slightly elevated among children with amalgam fillings, we found no evidence of adverse effects on the outcomes evaluated. These results agree with those from recent trials in developed countries.
journal_name
Int J Hyg Environ Healthauthors
Ye X,Qian H,Xu P,Zhu L,Longnecker MP,Fu Hdoi
10.1016/j.ijheh.2008.09.004subject
Has Abstractpub_date
2009-07-01 00:00:00pages
378-86issue
4eissn
1438-4639issn
1618-131Xpii
S1438-4639(08)00080-1journal_volume
212pub_type
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journal_title:International journal of hygiene and environmental health
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更新日期:2019-03-01 00:00:00
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
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abstract::Phenols and parabens are used in a multitude of consumer products resulting in ubiquitous human exposure. Animal and in vitro studies suggest that exposure to these compounds may be related to a number of adverse health outcomes, as well as potential mediators such as oxidative stress and inflammation. We examined uri...
journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2009.03.003
更新日期:2009-09-01 00:00:00
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journal_title:International journal of hygiene and environmental health
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2008.01.001
更新日期:2009-01-01 00:00:00
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更新日期:2021-01-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2019.113419
更新日期:2020-03-01 00:00:00
abstract::This paper provides the first baseline information on a national scale regarding lead exposure in the Spanish adult population. Blood lead levels were measured in a representative sample of the Spanish working population (1880 subjects aged 18-65 years) in order to help establish reference levels, follow temporal tren...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2013.09.001
更新日期:2014-04-01 00:00:00
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journal_title:International journal of hygiene and environmental health
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doi:10.1016/j.ijheh.2016.07.007
更新日期:2016-10-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.04.007
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journal_title:International journal of hygiene and environmental health
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更新日期:2015-08-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2010.09.005
更新日期:2010-11-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2005.01.009
更新日期:2005-01-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.03.015
更新日期:2017-08-01 00:00:00
abstract::A national survey was conducted to determine polychlorinated dibenzo-p-dioxins and dibenofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in human milk samples collected from 16 provinces in China to assess current exposure and temporal trends in China. The arithmetic mean concentration of total TE...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.07.013
更新日期:2016-11-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.12.010
更新日期:2017-04-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 历史文章,杂志文章
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更新日期:2007-05-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.11.004
更新日期:2018-03-01 00:00:00
abstract::Ultimately, the health and quality of life of all human beings depend upon the environment and ecosystems to which we are directly and indirectly connected. The papers in this special edition address a number of the critical environmental health issues on which U.S. government agencies and their collaborating partners...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00221
更新日期:2003-08-01 00:00:00