当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH期刊下所有文献 > Association of Carbon Monoxide exposure with blood pressure among pregnant women in rural Ghana: Evidence from GRAPHS.

Association of Carbon Monoxide exposure with blood pressure among pregnant women in rural Ghana: Evidence from GRAPHS.

Abstract：

BACKGROUND AND OBJECTIVE:The Ghana Randomized Air Pollution and Health Study (GRAPHS) is a community-level randomized-controlled trial of cookstove interventions for pregnant women and their newborns in rural Ghana. Given that household air pollution from biomass burning may be implicated in adverse cardiovascular outcomes, we sought to determine whether exposure to carbon monoxide (CO) from woodsmoke was associated with blood pressure (BP) among 817 adult women. METHODS:Multivariate linear regression models were used to evaluate the association between CO exposure, determined with 72 hour personal monitoring at study enrollment, and BP, also measured at study enrollment. At the time of these assessments, women were in the first or second trimester of pregnancy. RESULTS:A significant positive association was found between CO exposure and diastolic blood pressure (DBP): on average, each 1 ppm increase in exposure to CO was associated with 0.43 mmHg higher DBP [0.01, 0.86]. A non-significant positive trend was also observed for systolic blood pressure (SBP). CONCLUSION:This study is one of very few to have examined the relationship between household air pollution and blood pressure among pregnant women, who are at particular risk for hypertensive complications. The results of this cross-sectional study suggest that household air pollution from wood-burning fires is associated with higher blood pressure, particularly DBP, in pregnant women at early to mid-gestation. The clinical implications of the observed association toward the eventual development of chronic hypertension and/or hypertensive complications of pregnancy remain uncertain, as few of the women were overtly hypertensive at this point in their pregnancies.

journal_name

Int J Hyg Environ Health

journal_title

International journal of hygiene and environmental health

authors

Quinn AK,Ae-Ngibise KA,Jack DW,Boamah EA,Enuameh Y,Mujtaba MN,Chillrud SN,Wylie BJ,Owusu-Agyei S,Kinney PL,Asante KP

doi

10.1016/j.ijheh.2015.10.004

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

176-83

issue

eissn

1438-4639

issn

1618-131X

pii

S1438-4639(15)00138-8

journal_volume

219

pub_type

杂志文章,随机对照试验

在线工具

Association of Carbon Monoxide exposure with blood pressure among pregnant women in rural Ghana: Evidence from GRAPHS.